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The chronic CSF leak led to acquired Chiari malformation (CM) with syringomyelia. After an epidural blood patch, her neurological status improved; however, after the complete arrest of the CSF leak from the thigh, she presented with severe nonpostural headache and progressive visual acuity loss with optic papilledema. A ventriculoperitoneal shunt was placed to treat intracranial hypertension (50 cm H<jats:sub>2<\/jats:sub>O). Headache improved and optic papilledema decreased after shunt surgery. This case shows that dynamic CSF abnormalities may lead to reversible CM in patients with GSD. Sealing a CSF leak rather than performing suboccipital decompression is recommended for acquired CM resulting from a CSF leak.<\/jats:p>","DOI":"10.3171\/2018.5.peds1859","type":"journal-article","created":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T13:55:56Z","timestamp":1533304556000},"page":"508-512","source":"Crossref","is-referenced-by-count":14,"title":["Intracranial hypotension and hypertension: reversible Chiari malformation due to dynamic cerebrospinal fluid abnormalities in Gorham-Stout disease. 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