{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T14:52:18Z","timestamp":1793976738654,"version":"4.8.0"},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>Mechanical thrombectomy using a Solitaire stent retriever has been widely applied as a safe and effective method in adult acute ischemic stroke (AIS). However, due to the lack of data, the safety and effectiveness of mechanical thrombectomy using a Solitaire stent in pediatric AIS has not yet been verified. The purpose of this study was to explore the safety and effectiveness of mechanical thrombectomy using a Solitaire stent retriever for pediatric AIS.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Between January 2012 and December 2017, 7 cases of pediatric AIS were treated via mechanical thrombectomy using a Solitaire stent retriever. The clinical practice, imaging, and follow-up results were reviewed, and the data were summarized and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The ages of the 7 patients ranged from 7 to 14 years with an average age of 11.1 years. The preoperative National Institutes of Health Stroke Scale (NIHSS) scores ranged from 9 to 22 with an average of 15.4 points. A Solitaire stent retriever was used in all patients, averaging 1.7 applications of thrombectomy and combined balloon dilation in 2 cases. Grade 3 on the modified Thrombolysis In Cerebral Infarction scale of recanalization was achieved in 5 cases and grade 2b in 2 cases. Six patients improved and 1 patient died after thrombectomy. The average NIHSS score of the 6 cases was 3.67 at discharge. The average modified Rankin Scale score was 1 at the 3-month follow-up. Subarachnoid hemorrhage after thrombectomy occurred in 1 case and that patient died 3 days postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>This study shows that mechanical thrombectomy using a Solitaire stent retriever has a high recanalization rate and excellent clinical prognosis in pediatric AIS. The safety of mechanical thrombectomy in pediatric AIS requires more clinical trials for confirmation.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2018.9.peds18242","type":"journal-article","created":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T00:51:48Z","timestamp":1551228708000},"page":"363-368","source":"Crossref","is-referenced-by-count":17,"title":["Mechanical thrombectomy using a Solitaire stent retriever in the treatment of pediatric acute ischemic stroke"],"prefix":"10.3171","volume":"23","author":[{"given":"Bing","family":"Zhou","sequence":"first","affiliation":[{"name":"Departments of Interventional and Vascular Surgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Chuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou City, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Yi","family":"Xiang","sequence":"additional","affiliation":[{"name":"Departments of Interventional and Vascular Surgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Zhao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Departments of Interventional and Vascular Surgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Li","sequence":"additional","affiliation":[{"name":"Departments of Interventional and Vascular Surgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Bo","family":"Jiang","sequence":"additional","affiliation":[{"name":"Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou City, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Dong","family":"Lu","sequence":"additional","affiliation":[{"name":"Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou City, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Lancet Neurol","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S1474-4422(13)70290-4","article-title":"Childhood arterial ischaemic stroke incidence, presenting features, and risk factors: a prospective population-based study","volume":"13","author":"Mallick AA","year":"2014","unstructured":"Mallick AA, Ganesan V, Kirkham FJ, Fallon P, Hedderly T, McShane T, : Childhood arterial ischaemic stroke incidence, presenting features, and risk factors: a prospective population-based study. 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