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Case 2 was an infant girl referred for evaluation of a holohemispheric malignant neoplasm. Case 3 was an infant girl referred for evaluation of an intracranial mass believed to be a subdural empyema or possible sarcoma. In each case the lesion was resected and found to be a WHO grade I DIG. Each child has had a benign postoperative course. DIG can be mistaken for other serious neurological conditions including malignant neoplasm, cerebral infarction, and infection. It is prudent to consider this rare, low-grade resectable tumor in the differential diagnosis of atypical intracranial masses of childhood, as the impact on prognosis can be profound. The author discusses management strategies for DIG, including a role for molecular sequencing.<\/jats:p>","DOI":"10.3171\/2019.5.peds19151","type":"journal-article","created":{"date-parts":[[2019,7,5]],"date-time":"2019-07-05T21:53:42Z","timestamp":1562363622000},"page":"258-266","source":"Crossref","is-referenced-by-count":5,"title":["The great neurosurgical masquerader: 3 cases of desmoplastic infantile ganglioglioma"],"prefix":"10.3171","volume":"24","author":[{"given":"Alan R.","family":"Cohen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1159\/000149913","article-title":"Desmoplastic infantile ganglioglioma: a report of 2 cases and a review of the literature","volume":"44","author":"Alexiou GA","year":"2008","unstructured":"Alexiou GA, Stefanaki K, Sfakianos G, Prodromou N: Desmoplastic infantile ganglioglioma: a report of 2 cases and a review of the literature. 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