{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:52:39Z","timestamp":1791417159079,"version":"4.3.3"},"reference-count":40,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>Hospital readmission is a key component in value-based healthcare models but there are limited data about the 30-day readmission rate after endonasal endoscopic transsphenoidal surgery (EETS) for pituitary adenoma. The objective of this study was to determine the incidence and identify factors associated with 30-day readmission after EETS for pituitary adenoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>The authors analyzed a prospectively acquired database of patients who underwent EETS for pituitary adenoma from 2005 to 2018 at NewYork-Presbyterian Hospital, Weill Cornell Medicine. Clinical, socioeconomic, and radiographic data were reviewed for cases of unplanned readmission within 30 days of surgery and, as a control group, for all other patients in the series who were not readmitted. Statistical significance was determined with an alpha &lt; 0.05 using Pearson\u2019s chi-square and Fisher\u2019s exact tests for categorical variables and the independent-samples t-test for continuous variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Of 584 patients undergoing EETS for pituitary adenoma, 27 (4.6%) had unplanned readmission within 30 days. Most readmissions occurred within the first week after surgery, with a mean time to readmission of 6.6 \u00b1 3.9 days. The majority of readmissions (59%) were for hyponatremia. These patients had a mean sodium level of 120.6 \u00b1 4.6 mEq\/L at presentation. Other causes of readmission were epistaxis (11%), spinal headache (11%), sellar hematoma (7.4%), CSF leak (3.7%), nonspecific headache (3.7%), and pulmonary embolism (3.7%). The postoperative length of stay was significantly shorter for patients who were readmitted than for the controls (2.7 \u00b1 1.0 days vs 3.9 \u00b1 3.2 days; p &lt; 0.05). Patients readmitted for hyponatremia had an initial length of stay of 2.6 \u00b1 0.9 days, the shortest of any cause for readmission. The mean BMI was significantly lower for readmitted patients than for the controls (26.4 \u00b1 3.9 kg\/m<jats:sup>2<\/jats:sup> vs 29.3 \u00b1 6.1 kg\/m<jats:sup>2<\/jats:sup>; p &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Readmission after EETS for pituitary adenoma is a relatively rare phenomenon, with delayed hyponatremia being the primary cause. The study results demonstrate that shorter postoperative length of stay and lower BMI were associated with 30-day readmission.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2019.7.jns191558","type":"journal-article","created":{"date-parts":[[2019,9,28]],"date-time":"2019-09-28T05:57:58Z","timestamp":1569650278000},"page":"1242-1247","source":"Crossref","is-referenced-by-count":30,"title":["Readmission after endoscopic transsphenoidal pituitary surgery: analysis of 584 consecutive cases"],"prefix":"10.3171","volume":"133","author":[{"given":"Iyan","family":"Younus","sequence":"first","affiliation":[{"name":"Weill Cornell Medical College, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina M.","family":"Gerges","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"},{"name":"Department of Neurosurgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgiana A.","family":"Dobri","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"},{"name":"Neuroscience, and"},{"name":"Endocrinology, Weill Cornell Medical College, NewYork-Presbyterian Hospital, New York, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan","family":"Ramakrishna","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore H.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"},{"name":"Otolaryngology,"},{"name":"Neuroscience, and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Semin Nephrol","first-page":"23","article-title":"Structural renal changes in obesity and diabetes","volume":"33","author":"Amann K","year":"2013","unstructured":"Amann K, Benz K: Structural renal changes in obesity and diabetes. 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