{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T02:25:35Z","timestamp":1794018335609,"version":"4.8.0"},"reference-count":39,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8]]},"abstract":"\n OBJECTIVE<\/jats:title>\n Scoliosis is common in patients with Chiari malformation type I (CM-I)\u2013associated syringomyelia. While it is known that treatment with posterior fossa decompression (PFD) may reduce the progression of scoliosis, it is unknown if decompression with duraplasty is superior to extradural decompression.<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n A large multicenter retrospective and prospective registry of 1257 pediatric patients with CM-I (tonsils \u2265 5 mm below the foramen magnum) and syrinx (\u2265 3 mm in axial width) was reviewed for patients with scoliosis who underwent PFD with or without duraplasty.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n In total, 422 patients who underwent PFD had a clinical diagnosis of scoliosis. Of these patients, 346 underwent duraplasty, 51 received extradural decompression alone, and 25 were excluded because no data were available on the type of PFD. The mean clinical follow-up was 2.6 years. Overall, there was no difference in subsequent occurrence of fusion or proportion of patients with curve progression between those with and those without a duraplasty. However, after controlling for age, sex, preoperative curve magnitude, syrinx length, syrinx width, and holocord syrinx, extradural decompression was associated with curve progression > 10\u00b0, but not increased occurrence of fusion. Older age at PFD and larger preoperative curve magnitude were independently associated with subsequent occurrence of fusion. Greater syrinx reduction after PFD of either type was associated with decreased occurrence of fusion.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n In patients with CM-I, syrinx, and scoliosis undergoing PFD, there was no difference in subsequent occurrence of surgical correction of scoliosis between those receiving a duraplasty and those with an extradural decompression. However, after controlling for preoperative factors including age, syrinx characteristics, and curve magnitude, patients treated with duraplasty were less likely to have curve progression than patients treated with extradural decompression. Further study is needed to evaluate the role of duraplasty in curve stabilization after PFD.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2020.12.peds20552","type":"journal-article","created":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T03:10:26Z","timestamp":1623985826000},"page":"167-175","source":"Crossref","is-referenced-by-count":11,"title":["Extradural decompression versus duraplasty in Chiari malformation type I with syrinx: outcomes on scoliosis from the Park-Reeves Syringomyelia Research Consortium"],"prefix":"10.3171","volume":"28","author":[{"given":"Brooke","family":"Sadler","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Washington University in St. Louis, MO;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Skidmore","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Gewirtz","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard C. 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