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Follow-up serial ultrasound showed resolving intraventricular hemorrhage and progressive bilateral hydrocephalus. At 5 weeks, the ductus was ligated with the goal of improving hemodynamic stability prior to CSF diversion. However, neurosurgical intervention was not required due to improvement of ventriculomegaly occurring immediately after PDA ligation. No further ventricular dilation was observed at the 6-month follow-up.<\/jats:p><jats:p>Systemic venous flow disruption and abnormal patterns of cerebral blood circulation have been previously associated with hsPDA. Systemic hemodynamic change has been reported to follow hsPDA ligation, although association with ventricular normalization has not. This case suggests that the unstable hemodynamic environment due to left-to-right shunting may also impede CSF outflow and contribute to ventriculomegaly. The authors review the literature surrounding pressure transmission between a PDA and the cerebral vessels and present a mechanism by which PDA may contribute to posthemorrhagic ventricular dilation.<\/jats:p>","DOI":"10.3171\/2020.3.peds19694","type":"journal-article","created":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T07:06:56Z","timestamp":1590131216000},"page":"255-261","source":"Crossref","is-referenced-by-count":2,"title":["Resolution of neonatal posthemorrhagic ventricular dilation coincident with patent ductus arteriosus ligation: case report"],"prefix":"10.3171","volume":"26","author":[{"given":"Erik B.","family":"Vanstrum","sequence":"first","affiliation":[{"name":"Keck School of Medicine of University of Southern California, Los Angeles; and Divisions of"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew T.","family":"Borzage","sequence":"additional","affiliation":[{"name":"Neonatology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason K.","family":"Chu","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of University of Southern California, Los Angeles; and Divisions of"},{"name":"Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuo","family":"Wang","sequence":"additional","affiliation":[{"name":"Cardiology, Children\u2019s Hospital Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nolan","family":"Rea","sequence":"additional","affiliation":[{"name":"Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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