{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T01:40:44Z","timestamp":1792201244511,"version":"4.4.0"},"reference-count":15,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Perforator arteries, the absence of an aneurysm discrete neck, and the often-extensive nature of posterior circulation fusiform aneurysms present treatment challenges. There have been advances in microsurgical and endovascular approaches, including flow diversion, and the authors sought to review these treatments in a long-term series at their neurovascular referral center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The authors performed a retrospective chart review from 1990 to 2018. Primary outcomes were modified Rankin Scale (mRS) scores and Glasgow Outcome Scale (GOS) scores at follow-up. The authors also examined neurological complication rates. Using regression techniques, they reviewed independent and dependent variables, including presenting features, aneurysm location and size, surgical approach, and pretreatment and posttreatment thrombosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Eighty-four patients met the inclusion criteria. Their mean age was 53 years, and 49 (58%) were female. Forty-one (49%) patients presented with subarachnoid hemorrhage. Aneurysms were located on the vertebral artery (VA) or posterior inferior cerebellar artery (PICA) in 50 (60%) patients, basilar artery (BA) or vertebrobasilar junction (VBJ) in 22 (26%), and posterior cerebral artery (PCA) in 12 (14%). Thirty-one (37%) patients were treated with microsurgical and 53 (63%) with endovascular approaches. Six aneurysms were treated with endovascular flow diversion. The authors found moderate disability or better (mRS score \u2264 3) in 85% of the patients at a mean 14-month follow-up. The GOS score was \u2265 4 in 82% of the patients. The overall neurological complication rate was 12%. In the regression analysis, patients with VA or PICA aneurysms had better functional outcomes than the other groups (p &lt; 0.001). Endovascular strategies were associated with better outcomes for BA-VBJ aneurysms (p &lt; 0.01), but microsurgery was associated with better outcomes for VA-PICA and PCA aneurysms (p &lt; 0.05). There were no other significant associations between patient, aneurysm characteristics, or treatment features and neurological complications (p &gt; 0.05). Patients treated with flow diversion had more complications than those who underwent other endovascular and microsurgical strategies, but the difference was not significant in regression models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Posterior circulation fusiform aneurysms remain a challenging aneurysm subtype, but an interdisciplinary treatment approach can result in good outcomes. While flow diversion is a useful addition to the armamentarium, traditional endovascular and microsurgical techniques continue to offer effective options.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2020.4.jns192838","type":"journal-article","created":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T03:47:11Z","timestamp":1601610431000},"page":"1894-1900","source":"Crossref","is-referenced-by-count":26,"title":["Treatment of posterior circulation fusiform aneurysms"],"prefix":"10.3171","volume":"134","author":[{"given":"Ephraim W.","family":"Church","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark G.","family":"Bigder","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric S.","family":"Sussman","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santosh E.","family":"Gummidipundi","sequence":"additional","affiliation":[{"name":"Quantitative Sciences Unit, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Summer S.","family":"Han","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"},{"name":"Quantitative Sciences Unit, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy J.","family":"Heit","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"},{"name":"Radiology, and Stanford Stroke Center; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huy M.","family":"Do","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"},{"name":"Radiology, and Stanford Stroke Center; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Dodd","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"},{"name":"Radiology, and Stanford Stroke Center; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Marks","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"},{"name":"Radiology, and Stanford Stroke Center; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary K.","family":"Steinberg","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"1","key":"b1","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"82","DOI":"10.3171\/jns.2004.101.1.0082","article-title":"Prospective risk of hemorrhage in patients with vertebrobasilar nonsaccular intracranial aneurysm","volume":"101","author":"Flemming\n \nKD","year":"2004","unstructured":"Flemming\n \nKD\n\n, \n\nWiebers\n \nDO\n\n, \n\nBrown\n \nRD\n \nJr\n\n, \n\n\n \nProspective risk of hemorrhage in patients with vertebrobasilar nonsaccular intracranial aneurysm\n. \nJ Neurosurg\n. \n2004\n;\n101\n(\n1\n):\n82\n\u2013\n87\n.\n10.3171\/jns.2004.101.1.008215255255"},{"issue":"1","key":"b2","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"72","DOI":"10.3171\/jns.2005.102.1.0072","article-title":"Enlarging vertebrobasilar nonsaccular intracranial aneurysms: frequency, predictors, and clinical outcome of growth","volume":"102","author":"Mangrum\n \nWI","year":"2005","unstructured":"Mangrum\n \nWI\n\n, \n\nHuston\n \nJ\n \nIII\n\n, \n\nLink\n \nMJ\n\n, \n\n\n \nEnlarging vertebrobasilar nonsaccular intracranial aneurysms: frequency, predictors, and clinical outcome of growth\n. \nJ Neurosurg\n. \n2005\n;\n102\n(\n1\n):\n72\n\u2013\n79\n.\n1565809910.3171\/jns.2005.102.1.0072"},{"issue":"2","key":"b3","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"161","DOI":"10.3171\/jns.1993.79.2.0161","article-title":"Deliberate basilar or vertebral artery occlusion in the treatment of intracranial aneurysms. 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