{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T10:51:15Z","timestamp":1789123875488,"version":"build-2803163510"},"reference-count":28,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Frailty has been recognized as a predictor of adverse surgical outcomes across multiple surgical disciplines, but until now the relationship between frailty and intracranial meningioma surgery has not been studied. The goal of the present study was to determine the relationship between increasing frailty (determined using the modified Frailty Index [mFI]) and intracranial meningioma resection outcomes (including hospital length of stay [LOS], discharge location, and reoperation and readmission rates).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>This is a single-center retrospective cohort study of patients who underwent intracranial meningioma resection between August 2012 and May 2018. Seventy-six patients met the inclusion criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Frailty was associated with increased hospital LOS (p = 0.0218), increased reoperation rate (p = 0.029), and discharge to a higher level of care: an inpatient rehabilitation facility or a skilled nursing facility (p = 0.0002). After multivariable analysis, frailty was determined to be an independent risk factor for increased LOS, worse discharge disposition, and subsequent readmission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Frailty is an independent risk factor for worse outcomes following intracranial meningioma resection, including increased LOS, reoperations, and worse discharge disposition. Frailty may help stratify preoperative surgical risk, and thus may provide important clinical information to help neurosurgeons and elderly patients weigh the risks and benefits of resection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2020.7.focus20324","type":"journal-article","created":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T07:15:57Z","timestamp":1601536557000},"page":"E16","source":"Crossref","is-referenced-by-count":45,"title":["Frailty predicts worse outcomes after intracranial meningioma surgery irrespective of existing prognostic factors"],"prefix":"10.3171","volume":"49","author":[{"given":"Brianna C.","family":"Theriault","sequence":"first","affiliation":[{"name":"School of Medicine, New York Medical College, Valhalla, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Pazniokas","sequence":"additional","affiliation":[{"name":"School of Medicine, New York Medical College, Valhalla, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anusha S.","family":"Adkoli","sequence":"additional","affiliation":[{"name":"School of Medicine, New York Medical College, Valhalla, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward K.","family":"Cho","sequence":"additional","affiliation":[{"name":"School of Medicine, New York Medical College, Valhalla, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naina","family":"Rao","sequence":"additional","affiliation":[{"name":"School of Medicine, New York Medical College, Valhalla, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meic","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of New Mexico, Albuquerque, New Mexico; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chad","family":"Cole","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Westchester Medical Center, Valhalla, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chirag","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Westchester Medical Center, Valhalla, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William T.","family":"Couldwell","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Utah, Salt Lake City, Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fawaz","family":"Al-Mufti","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Westchester Medical Center, Valhalla, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian A.","family":"Bowers","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of New Mexico, Albuquerque, New Mexico; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"2","key":"b1","series-title":"J Neurooncol","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/s11060-019-03104-3","article-title":"Incidental intracranial meningiomas: a systematic review and meta-analysis of prognostic factors and outcomes","volume":"142","author":"Islim AI","year":"2019","unstructured":"Islim AI, Mohan M, Moon RDC,  Incidental intracranial meningiomas: a systematic review and meta-analysis of prognostic factors and outcomes. 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