{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T10:50:40Z","timestamp":1792234240654,"version":"4.4.0"},"reference-count":58,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10]]},"abstract":"\n OBJECTIVE<\/jats:title>\n The objective of this study was to analyze the risk factors associated with the outcome of acute subdural hematoma (ASDH) in elderly patients treated either surgically or nonsurgically.<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n The authors performed a retrospective multicentric analysis of clinical and radiological data on patients aged \u2265 70 years who had been consecutively admitted to the neurosurgical department of 5 Italian hospitals for the management of posttraumatic ASDH in a 3-year period. Outcome was measured according to the Glasgow Outcome Scale (GOS) at discharge and at 6 months\u2019 follow-up. A GOS score of 1\u20133 was defined as a poor outcome and a GOS score of 4\u20135 as a good outcome. Univariate and multivariate statistics were used to determine outcome predictors in the entire study population and in the surgical group.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n Overall, 213 patients were admitted during the 3-year study period. Outcome was poor in 135 (63%) patients, as 65 (31%) died during their admission, 33 (15%) were in a vegetative state, and 37 (17%) had severe disability at discharge. Surgical patients had worse clinical and radiological findings on arrival or during their admission than the patients undergoing conservative treatment. Surgery was performed in 147 (69%) patients, and 114 (78%) of them had a poor outcome. In stratifying patients by their Glasgow Coma Scale (GCS) score, the authors found that surgery reduced mortality but not the frequency of a poor outcome in the patients with a moderate to severe GCS score. The GCS score and midline shift were the most significant predictors of outcome. Antiplatelet drugs were associated with better outcomes; however, patients taking such medications had a better GCS score and better radiological findings, which could have influenced the former finding. Patients with fixed pupils never had a good outcome. Age and Charlson Comorbidity Index were not associated with outcome.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n Traumatic ASDH in the elderly is a severe condition, with the GCS score and midline shift the stronger outcome predictors, while age per se and comorbidities were not associated with outcome. Antithrombotic drugs do not seem to negatively influence pretreatment status or posttreatment outcome. Surgery was performed in patients with a worse clinical and radiological status, reducing the rate of death but not the frequency of a poor outcome.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2020.7.focus20437","type":"journal-article","created":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T07:15:57Z","timestamp":1601536557000},"page":"E21","source":"Crossref","is-referenced-by-count":54,"title":["Acute subdural hematoma in the elderly: outcome analysis in a retrospective multicentric series of 213 patients"],"prefix":"10.3171","volume":"49","author":[{"given":"Gianluca","family":"Trevisi","sequence":"first","affiliation":[{"name":"Neurosurgical Unit, Ospedale Santo Spirito, Pescara;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmelo Lucio","family":"Sturiale","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fondazione Policlinico Universitario A. 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