{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T23:06:12Z","timestamp":1794006372110,"version":"4.8.0"},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>Several radiological parameters related to the aging spine have been reported as progression factors of early degenerative lumbar scoliosis (DLS). However, it has not been determined which factors are the most important. In this study the authors aimed to determine the risk factors associated with curve progression in early DLS.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>Fifty-one patients with early DLS and Cobb angles of 5\u00b0\u201315\u00b0 were investigated. In total, 7 men and 44 women (mean age 61.6 years) were observed for a mean period of 13.7 years. The subjects were divided into two groups according to Cobb angle progression (\u2265 15\u00b0 or &lt; 15\u00b0) at the final follow-up, and radiological parameters were compared. The direction of scoliosis, apical vertebral level and rotational grade, lateral subluxation, disc space difference, osteophyte difference, upper and lower disc wedging angles, and relationship between the intercrest line and L5 vertebra were evaluated.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>During the follow-up period, the mean curve progression increased from 8.8\u00b0 \u00b1 3.2\u00b0 to 19.4\u00b0 \u00b1 8.9\u00b0. The Cobb angle had progressed by \u2265 15\u00b0 in 17 patients (33.3%) at the final follow-up. In these patients the mean Cobb angle increased from 9.4\u00b0 \u00b1 3.4\u00b0 to 28.8\u00b0 \u00b1 7.5\u00b0, and in the 34 remaining patients it increased from 8.5\u00b0 \u00b1 3.1\u00b0 to 14.7\u00b0 \u00b1 4.8\u00b0. The baseline lateral subluxation, disc space difference, and upper and lower disc wedging angles significantly differed between the groups. In multivariate logistic regression analysis, only the upper and lower disc wedging angles were significantly correlated with curve progression (OR 1.55, p = 0.035, and OR 1.89, p = 0.004, respectively).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>Asymmetrical degenerative change in the lower apical vertebral disc, which leads to upper and lower disc wedging angles, is the most substantial factor in predicting early DLS progression.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2020.7.spine20266","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T07:20:31Z","timestamp":1610695231000},"page":"557-563","source":"Crossref","is-referenced-by-count":7,"title":["Radiologic prognostic factors of curve progression in early degenerative lumbar scoliosis"],"prefix":"10.3171","volume":"34","author":[{"given":"Jin-Sung","family":"Park","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se-Jun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong-Suh","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-hoon","family":"Yum","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo-Taek","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Korea University Ansan Hospital, Gyeonggi-do, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"10","key":"b1","series-title":"Eur Spine J","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1007\/s00586-005-1053-9","article-title":"The adult scoliosis","volume":"14","author":"Aebi \nM","year":"2005","unstructured":"Aebi \nM\n\n. \nThe adult scoliosis. \nEur Spine J. \n2005;\n14(\n10):\n925\u2013\n948.\n10.1007\/s00586-005-1053-916328223"},{"issue":"3","key":"b2","series-title":"Neurosurg Clin N Am","first-page":"299","article-title":"Degenerative lumbar scoliosis","volume":"17","author":"Oskouian \nRJ \nJr","year":"2006","unstructured":"Oskouian \nRJ \nJr\n, \n\nShaffrey \nCI\n\n. \nDegenerative lumbar scoliosis. \nNeurosurg Clin N Am. \n2006;\n17(\n3):\n299\u2013\n315, \nvii.\n16876030"},{"issue":"6","key":"b3","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1097\/00007632-199305000-00004","article-title":"Degenerative symptomatic lumbar scoliosis","volume":"18","author":"Pritchett \nJW","year":"1993","unstructured":"Pritchett \nJW\n, \n\nBortel \nDT\n\n. \nDegenerative symptomatic lumbar scoliosis. \nSpine (Phila Pa 1976). \n1993;\n18(\n6):\n700\u2013\n703.\n10.1097\/00007632-199305000-00004"},{"issue":"4","key":"b4","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1097\/00007632-198207000-00005","article-title":"Scoliosis in the elderly: a follow-up study","volume":"7","author":"Robin \nGC","year":"1982","unstructured":"Robin \nGC\n, \n\nSpan \nY\n, \n\nSteinberg \nR\n, \n\n \nScoliosis in the elderly: a follow-up study. \nSpine (Phila Pa 1976). \n1982;\n7(\n4):\n355\u2013\n359.\n10.1097\/00007632-198207000-00005"},{"issue":"14","key":"b5","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.1097\/01.brs.0000170293.81234.f0","article-title":"A lumbar classification of scoliosis in the adult patient: preliminary approach","volume":"30","author":"Schwab \nF","year":"2005","unstructured":"Schwab \nF\n, \n\nel-Fegoun \nAB\n, \n\nGamez \nL\n, \n\n \nA lumbar classification of scoliosis in the adult patient: preliminary approach. \nSpine (Phila Pa 1976). \n2005;\n30(\n14):\n1670\u2013\n1673.\n10.1097\/01.brs.0000170293.81234.f0"},{"issue":"4","key":"b6","series-title":"J Bone Joint Surg Am","doi-asserted-by":"publisher","first-page":"447","DOI":"10.2106\/00004623-198365040-00004","article-title":"Curve progression in idiopathic scoliosis","volume":"65","author":"Weinstein \nSL","year":"1983","unstructured":"Weinstein \nSL\n, \n\nPonseti \nIV\n\n. \nCurve progression in idiopathic scoliosis. \nJ Bone Joint Surg Am. \n1983;\n65(\n4):\n447\u2013\n455.\n10.2106\/00004623-198365040-000046833318"},{"issue":"9","key":"b7","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1097\/01.brs.0000160842.43482.cd","article-title":"Adult scoliosis: prevalence, SF-36, and nutritional parameters in an elderly volunteer population","volume":"30","author":"Schwab \nF","year":"2005","unstructured":"Schwab \nF\n, \n\nDubey \nA\n, \n\nGamez \nL\n, \n\n \nAdult scoliosis: prevalence, SF-36, and nutritional parameters in an elderly volunteer population. \nSpine (Phila Pa 1976). \n2005;\n30(\n9):\n1082\u2013\n1085.\n10.1097\/01.brs.0000160842.43482.cd"},{"issue":"4","key":"b8","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1097\/00007632-200202150-00012","article-title":"Adult scoliosis: a quantitative radiographic and clinical analysis","volume":"27","author":"Schwab \nFJ","year":"2002","unstructured":"Schwab \nFJ\n, \n\nSmith \nVA\n, \n\nBiserni \nM\n, \n\n \nAdult scoliosis: a quantitative radiographic and clinical analysis. \nSpine (Phila Pa 1976). \n2002;\n27(\n4):\n387\u2013\n392.\n10.1097\/00007632-200202150-00012"},{"issue":"3","key":"b9","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E1","DOI":"10.3171\/2010.1.FOCUS09271","article-title":"Adult degenerative scoliosis: evaluation and management","volume":"28","author":"Silva \nFE","year":"2010","unstructured":"Silva \nFE\n, \n\nLenke \nLG\n\n. \nAdult degenerative scoliosis: evaluation and management. \nNeurosurg Focus. \n2010;\n28(\n3):\nE1.\n10.3171\/2010.1.FOCUS0927120192655"},{"issue":"6","key":"b10","series-title":"J Orthop Sci","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1007\/s00776-013-0444-8","article-title":"The differently expressed proteins in MSCs of degenerative scoliosis","volume":"18","author":"Han \nS","year":"2013","unstructured":"Han \nS\n, \n\nZhu \nY\n, \n\nWu \nZ\n, \n\n \nThe differently expressed proteins in MSCs of degenerative scoliosis. \nJ Orthop Sci. \n2013;\n18(\n6):\n885\u2013\n892.\n10.1007\/s00776-013-0444-823934146"},{"issue":"21","key":"b11","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.1097\/BRS.0b013e318221a65f","article-title":"Genetic predisposition in degenerative lumbar scoliosis due to the copy number variation","volume":"36","author":"Shin \nJH","year":"2011","unstructured":"Shin \nJH\n, \n\nHa \nKY\n, \n\nJung \nSH\n, \n\nChung \nYJ\n\n. \nGenetic predisposition in degenerative lumbar scoliosis due to the copy number variation. \nSpine (Phila Pa 1976). \n2011;\n36(\n21):\n1782\u2013\n1793.\n10.1097\/BRS.0b013e318221a65f"},{"issue":"8","key":"b12","series-title":"Am J Orthop","first-page":"404","article-title":"Risk of progression in de novo low-magnitude degenerative lumbar curves: natural history and literature review","volume":"38","author":"Chin \nKR","year":"2009","unstructured":"Chin \nKR\n, \n\nFurey \nC\n, \n\nBohlman \nHH\n\n. \nRisk of progression in de novo low-magnitude degenerative lumbar curves: natural history and literature review. \nAm J Orthop. \n2009;\n38(\n8):\n404\u2013\n409.\n19809605"},{"issue":"17","key":"b13","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"1926","DOI":"10.1097\/00007632-199409000-00012","article-title":"Adult idiopathic lumbar scoliosis. A formula for prediction of progression and review of the literature","volume":"19","author":"Korovessis \nP","year":"1994","unstructured":"Korovessis \nP\n, \n\nPiperos \nG\n, \n\nSidiropoulos \nP\n, \n\nDimas \nA\n\n. \nAdult idiopathic lumbar scoliosis. A formula for prediction of progression and review of the literature. \nSpine (Phila Pa 1976). \n1994;\n19(\n17):\n1926\u2013\n1932.\n10.1097\/00007632-199409000-00012"},{"issue":"5","key":"b14","series-title":"J Neurosurg Spine","doi-asserted-by":"publisher","first-page":"558","DOI":"10.3171\/2011.6.SPINE10929","article-title":"Risk of progression of degenerative lumbar scoliosis","volume":"15","author":"Seo \nJY","year":"2011","unstructured":"Seo \nJY\n, \n\nHa \nKY\n, \n\nHwang \nTH\n, \n\n \nRisk of progression of degenerative lumbar scoliosis. \nJ Neurosurg Spine. \n2011;\n15(\n5):\n558\u2013\n566.\n2178086110.3171\/2011.6.SPINE10929"},{"key":"b15","series-title":"Scoliosis","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/1748-7161-3-16","article-title":"Vertebral rotation measurement: a summary and comparison of common radiographic and CT methods","volume":"3","author":"Lam \nGC","year":"2008","unstructured":"Lam \nGC\n, \n\nHill \nDL\n, \n\nLe \nLH\n, \n\n \nVertebral rotation measurement: a summary and comparison of common radiographic and CT methods. \nScoliosis. \n2008;\n3:\n16.\n10.1186\/1748-7161-3-1618976498"},{"issue":"2","key":"b16","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1097\/01.brs.0000194777.87055.1b","article-title":"A prospective study of de novo scoliosis in a community based cohort","volume":"31","author":"Kobayashi \nT","year":"2006","unstructured":"Kobayashi \nT\n, \n\nAtsuta \nY\n, \n\nTakemitsu \nM\n, \n\n \nA prospective study of de novo scoliosis in a community based cohort. \nSpine (Phila Pa 1976). \n2006;\n31(\n2):\n178\u2013\n182.\n10.1097\/01.brs.0000194777.87055.1b"},{"issue":"2","key":"b17","series-title":"J Orthop Surg (Hong Kong)","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1177\/230949901101900202","article-title":"Factors predicting progression in early degenerative lumbar scoliosis","volume":"19","author":"Kohno \nS","year":"2011","unstructured":"Kohno \nS\n, \n\nIkeuchi \nM\n, \n\nTaniguchi \nS\n, \n\n \nFactors predicting progression in early degenerative lumbar scoliosis. \nJ Orthop Surg (Hong Kong). \n2011;\n19(\n2):\n141\u2013\n144.\n10.1177\/230949901101900202"},{"key":"b18","series-title":"Clin Orthop Relat Res","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1097\/00003086-198205000-00015","article-title":"Instability of the lumbar spine","volume":"165","author":"Kirkaldy-Willis \nWH","year":"1982","unstructured":"Kirkaldy-Willis \nWH\n, \n\nFarfan \nHF\n\n. \nInstability of the lumbar spine. \nClin Orthop Relat Res. \n1982;(\n165):\n110\u2013\n123.\n10.1097\/00003086-198205000-00015"},{"issue":"6","key":"b19","series-title":"Eur Spine J","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1007\/s00586-013-2678-8","article-title":"Degenerative lumbar scoliosis in Chinese Han population: prevalence and relationship to age, gender, bone mineral density, and body mass index","volume":"22","author":"Xu \nL","year":"2013","unstructured":"Xu \nL\n, \n\nSun \nX\n, \n\nHuang \nS\n, \n\n \nDegenerative lumbar scoliosis in Chinese Han population: prevalence and relationship to age, gender, bone mineral density, and body mass index. \nEur Spine J. \n2013;\n22(\n6):\n1326\u2013\n1331.\n10.1007\/s00586-013-2678-823361532"},{"issue":"6","key":"b20","series-title":"PLoS One","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0178697","article-title":"Sagittal spino-pelvic alignment in adults: the Wakayama Spine Study","volume":"12","author":"Asai \nY","year":"2017","unstructured":"Asai \nY\n, \n\nTsutsui \nS\n, \n\nOka \nH\n, \n\n \nSagittal spino-pelvic alignment in adults: the Wakayama Spine Study. \nPLoS One. \n2017;\n12(\n6):\ne0178697.\n10.1371\/journal.pone.017869728586366"},{"issue":"11","key":"b21","series-title":"Eur Spine J","doi-asserted-by":"publisher","first-page":"3675","DOI":"10.1007\/s00586-016-4702-2","article-title":"Normative values of spino-pelvic sagittal alignment, balance, age, and health-related quality of life in a cohort of healthy adult subjects","volume":"25","author":"Hasegawa \nK","year":"2016","unstructured":"Hasegawa \nK\n, \n\nOkamoto \nM\n, \n\nHatsushikano \nS\n, \n\n \nNormative values of spino-pelvic sagittal alignment, balance, age, and health-related quality of life in a cohort of healthy adult subjects. \nEur Spine J. \n2016;\n25(\n11):\n3675\u2013\n3686.\n10.1007\/s00586-016-4702-2"}],"container-title":["Journal of Neurosurgery: Spine"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/34\/4\/article-p557.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/34\/4\/article-p557.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/34\/4\/article-p557.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T01:00:47Z","timestamp":1751072447000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/34\/4\/article-p557.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":21,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/2020.7.spine20266","relation":{},"ISSN":["1547-5654"],"issn-type":[{"value":"1547-5654","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}