{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:38:12Z","timestamp":1792809492017,"version":"4.5.0"},"reference-count":14,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>Intractable epilepsy impacts many children. Surgically resective and palliative treatments have developed to increase seizure freedom or palliate the seizure burden in those with medically refractory epilepsy. However, surgical epilepsy treatment can confer significant morbidity and death. Endoscope-assisted surgical approaches may be helpful in reducing the morbidity related to traditional open surgical approaches while allowing for good visualization of surgical targets. Here, the authors report a case utilizing an endoscope-assisted keyhole approach to perform a posterior quadrantectomy and corpus callosotomy, achieving the surgical goals of disconnection and reducing the need for large craniotomy exposure. They present the case of a 17-year-old male with medically refractory epilepsy treated with endoscope-assisted posterior quadrantectomy and corpus callosotomy through two mini-craniotomies to achieve a functional disconnection. To the authors\u2019 knowledge, this is the first reported case of an endoscope-assisted approach for a posterior quadrantectomy for surgical epilepsy treatment in an adult or a pediatric patient. The case is reported to highlight the technical nuances and benefits of this approach in select patients as well as the expansion of applications of endoscope-assisted epilepsy surgery.<\/jats:p>","DOI":"10.3171\/2020.8.peds20432","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T02:09:32Z","timestamp":1610676572000},"page":"406-410","source":"Crossref","is-referenced-by-count":5,"title":["Endoscope-assisted posterior quadrant disconnection plus corpus callosotomy: case report"],"prefix":"10.3171","volume":"27","author":[{"given":"Melissa A.","family":"LoPresti","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Division of Pediatric Neurosurgery, Baylor College of Medicine, Texas Children\u2019s Hospital, Houston, Texas; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Division of Pediatric Neurosurgery, Baylor College of Medicine, Texas Children\u2019s Hospital, Houston, Texas; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandi","family":"Lam","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Division of Pediatric Neurosurgery, Northwestern University, Lurie Children\u2019s Hospital, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"31","key":"b1","series-title":"MMWR Morb Mortal Wkly Rep","doi-asserted-by":"publisher","first-page":"821","DOI":"10.15585\/mmwr.mm6631a1","article-title":"National and state estimates of the numbers of adults and children with active epilepsy\u2014United States, 2015","volume":"66","author":"Zack MM","year":"2017","unstructured":"Zack MM, \nKobau R\n. \nNational and state estimates of the numbers of adults and children with active epilepsy\u2014United States, 2015. MMWR Morb Mortal Wkly Rep. \n2017;\n66(\n31):\n821\u2013\n825.\n10.15585\/mmwr.mm6631a128796763"},{"issue":"1-2","key":"b2","series-title":"Epilepsy Res","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.eplepsyres.2011.03.009","article-title":"Incidence and classification of new-onset epilepsy and epilepsy syndromes in children in Olmsted County, Minnesota from 1980 to 2004: a population-based study","volume":"95","author":"Wirrell EC","year":"2011","unstructured":"Wirrell EC, \nGrossardt BR, \nWong-Kisiel LC, \nNickels KC\n. \nIncidence and classification of new-onset epilepsy and epilepsy syndromes in children in Olmsted County, Minnesota from 1980 to 2004: a population-based study. Epilepsy Res. \n2011;\n95(\n1-2):\n110\u2013\n118.\n2148207510.1016\/j.eplepsyres.2011.03.009"},{"issue":"1","key":"b3","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1111\/epi.12862","article-title":"The course of childhood-onset epilepsy over the first two decades: a prospective, longitudinal study","volume":"56","author":"Berg AT","year":"2015","unstructured":"Berg AT, \nRychlik K\n. \nThe course of childhood-onset epilepsy over the first two decades: a prospective, longitudinal study. Epilepsia. \n2015;\n56(\n1):\n40\u2013\n48.\n10.1111\/epi.1286225431231"},{"key":"b4","series-title":"Epilepsy Behav","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.yebeh.2014.05.031","article-title":"The consequences of refractory epilepsy and its treatment","volume":"37","author":"Laxer KD","year":"2014","unstructured":"Laxer KD, \nTrinka E, \nHirsch LJ, \n\n \nThe consequences of refractory epilepsy and its treatment. Epilepsy Behav. \n2014;\n37:\n59\u2013\n70.\n2498039010.1016\/j.yebeh.2014.05.031"},{"issue":"3","key":"b5","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1111\/epi.12912","article-title":"Increasing utilization of pediatric epilepsy surgery in the United States between 1997 and 2009","volume":"56","author":"Pestana Knight EM","year":"2015","unstructured":"Pestana Knight EM, \nSchiltz NK, \nBakaki PM, \n\n \nIncreasing utilization of pediatric epilepsy surgery in the United States between 1997 and 2009. Epilepsia. \n2015;\n56(\n3):\n375\u2013\n381.\n10.1111\/epi.1291225630252"},{"issue":"3","key":"b6","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"250","DOI":"10.3171\/2012.11.PEDS12359","article-title":"Sociodemographic changes over 25 years of pediatric epilepsy surgery at UCLA","volume":"11","author":"Hauptman JS","year":"2013","unstructured":"Hauptman JS, \nDadour A, \nOh T, \n\n \nSociodemographic changes over 25 years of pediatric epilepsy surgery at UCLA. J Neurosurg Pediatr. \n2013;\n11(\n3):\n250\u2013\n255.\n10.3171\/2012.11.PEDS1235923331214"},{"key":"b7","series-title":"Epilepsy Res","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.eplepsyres.2015.07.007","article-title":"Epilepsy surgery in the United States: analysis of data from the National Association of Epilepsy Centers","volume":"116","author":"Kaiboriboon K","year":"2015","unstructured":"Kaiboriboon K, \nMalkhachroum AM, \nZrik A, \n\n \nEpilepsy surgery in the United States: analysis of data from the National Association of Epilepsy Centers. Epilepsy Res. \n2015;\n116:\n105\u2013\n109.\n2631096910.1016\/j.eplepsyres.2015.07.007"},{"key":"b8","series-title":"Surg Neurol Int","doi-asserted-by":"publisher","first-page":"257","DOI":"10.25259\/SNI_417_2019","article-title":"An update on pediatric surgical epilepsy: part I","volume":"10","author":"Gadgil N","year":"2019","unstructured":"Gadgil N, \nLoPresti MA, \nMuir M, \n\n \nAn update on pediatric surgical epilepsy: part I. Surg Neurol Int. \n2019;\n10:\n257.\n10.25259\/SNI_417_201931893158"},{"issue":"3","key":"b9","series-title":"J Korean Neurosurg Soc","doi-asserted-by":"publisher","first-page":"336","DOI":"10.3340\/jkns.2019.0031","article-title":"From resection to disconnection for seizure control in pediatric epilepsy children","volume":"62","author":"Hwang JK","year":"2019","unstructured":"Hwang JK, \nKim D-S\n. \nFrom resection to disconnection for seizure control in pediatric epilepsy children. J Korean Neurosurg Soc. \n2019;\n62(\n3):\n336\u2013\n343.\n10.3340\/jkns.2019.003131085960"},{"issue":"8","key":"b10","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1111\/j.1528-1167.2007.01095.x","article-title":"Posterior quadrantic epilepsy surgery: technical variants, surgical anatomy, and case series","volume":"48","author":"Daniel RT","year":"2007","unstructured":"Daniel RT, \nMeagher-Villemure K, \nFarmer JP, \n\n \nPosterior quadrantic epilepsy surgery: technical variants, surgical anatomy, and case series. Epilepsia. \n2007;\n48(\n8):\n1429\u2013\n1437.\n1744199710.1111\/j.1528-1167.2007.01095.x"},{"issue":"2","key":"b11","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"178","DOI":"10.3171\/2018.8.PEDS18349","article-title":"Endoscope-assisted hemispherotomy: translation of technique from cadaveric anatomical feasibility study to clinical implementation","volume":"23","author":"Wagner K","year":"2018","unstructured":"Wagner K, \nVaz-Guimaraes F, \nCamstra K, \nLam S\n. \nEndoscope-assisted hemispherotomy: translation of technique from cadaveric anatomical feasibility study to clinical implementation. J Neurosurg Pediatr. \n2018;\n23(\n2):\n178\u2013\n186.\n10.3171\/2018.8.PEDS1834930497226"},{"issue":"suppl 1","key":"b12","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1111\/epi.13681","article-title":"Corpus callosotomy\u2014open and endoscopic surgical techniques","volume":"58","author":"Smyth MD","year":"2017","unstructured":"Smyth MD, \nVellimana AK, \nAsano E, \nSood S\n. \nCorpus callosotomy\u2014open and endoscopic surgical techniques. Epilepsia. \n2017;\n58(\nsuppl 1):\n73\u2013\n79.\n2838692310.1111\/epi.13681"},{"issue":"5","key":"b13","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1227\/NEU.0000000000001060","article-title":"Endoscopic-assisted (through a mini craniotomy) corpus callosotomy combined with anterior, hippocampal, and posterior commissurotomy in Lennox-Gastaut syndrome: a pilot study to establish its safety and efficacy","volume":"78","author":"Chandra SP","year":"2016","unstructured":"Chandra SP, \nKurwale NS, \nChibber SS, \n\n \nEndoscopic-assisted (through a mini craniotomy) corpus callosotomy combined with anterior, hippocampal, and posterior commissurotomy in Lennox-Gastaut syndrome: a pilot study to establish its safety and efficacy. 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Neurosurgery. \n2015;\n76(\n4):\n485\u2013\n495.\n2571010610.1227\/NEU.0000000000000675"}],"container-title":["Journal of Neurosurgery: Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/27\/4\/article-p406.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/27\/4\/article-p406.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/27\/4\/article-p406.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:55:23Z","timestamp":1792806923000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/27\/4\/article-p406.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":14,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/2020.8.peds20432","relation":{},"ISSN":["1933-0707","1933-0715"],"issn-type":[{"value":"1933-0707","type":"print"},{"value":"1933-0715","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}