{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T01:25:28Z","timestamp":1794014728143,"version":"4.8.0"},"reference-count":20,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Ischemic events within the territory of the choroidal artery are an important cause of morbidity after temporal lobe epilepsy (TLE) surgery. The aim of the present study was to evaluate the rate of these ischemic events, their clinical presentation, and impact on patients\u2019 health-related quality of life (HRQoL) after TLE surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Four hundred twenty-two consecutive patients undergoing temporal resections for drug-resistant TLE were retrospectively analyzed. All patients underwent presurgical multidisciplinary assessment using a standard protocol comprising clinical, neuroradiological, neuropsychological, and EEG data. Postoperative complications with corresponding imaging, neurological deficits, and disease-specific HRQoL questionnaires were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      The overall complication rate was 7.8% (n = 33). Fourteen patients (3.3%) suffered from ischemic events causing 6 permanent motor deficits, 3 with permanent aphasias, and 6 visual field defects that exceeded quadrantanopia. In 8 patients with anterior choroidal artery infarction, accounting for 57% of all ischemic events, infarction volume correlated positively with the occurrence of new permanent neurological deficits (8666 vs 1692 mm\n                      <jats:sup>3<\/jats:sup>\n                      , p = 0.032). Despite the occurrence of ischemic events, HRQoL improved in 71% of patients. However, infarction volume showed a negative correlation trend with HRQoL (Pearson\u2019s r = \u22120.390, p = 0.094). There was a trend toward increased risk for ischemic events in patients who underwent selective amygdalohippocampectomy compared to patients who underwent anterior temporal lobectomy or temporal lesionectomy (RR 0.96, 95% CI 0.93\u20130.99, p = 0.08).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Choroidal artery infarctions are rare but relevant complications after TLE surgery, presenting with variable clinical courses ranging from devastating neurological deterioration to complete recovery. Despite the occurrence of postoperative infarction, most patients report improvement of HRQoL after TLE surgery. This study showed that the type of surgery appears to modulate the risk for these ischemic events.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2021.1.jns203092","type":"journal-article","created":{"date-parts":[[2021,9,10]],"date-time":"2021-09-10T04:02:51Z","timestamp":1631246571000},"page":"536-542","source":"Crossref","is-referenced-by-count":7,"title":["Choroidal artery ischemic events after temporal lobe epilepsy surgery: clinical outcome, quality of life, and surgical pitfalls"],"prefix":"10.3171","volume":"136","author":[{"given":"Daniel","family":"Delev","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, RWTH University Aachen, University Medical Center, Aachen, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karlijn","family":"Hakvoort","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, RWTH University Aachen, University Medical Center, Aachen, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Therese","family":"Kr\u00fcger","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Cantonal Hospital St. Gallen, Switzerland; and"},{"name":"Department of Neurosurgery, Medical Center\u2013University of Freiburg, Faculty of Medicine, University of Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Blume","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, RWTH University Aachen, University Medical Center, Aachen, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Clusmann","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, RWTH University Aachen, University Medical Center, Aachen, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Neuloh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, RWTH University Aachen, University Medical Center, Aachen, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"Pt 11","key":"r1","series-title":"Brain","doi-asserted-by":"publisher","first-page":"2427","DOI":"10.1093\/brain\/awh267","article-title":"Life expectancy in people with newly diagnosed epilepsy","volume":"127","author":"Gaitatzis A","year":"2004","unstructured":"Gaitatzis A, Johnson AL, Chadwick DW,  Life expectancy in people with newly diagnosed epilepsy. 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