{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:47Z","timestamp":1782864047560,"version":"3.54.5"},"reference-count":10,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>The surgical treatment of moyamoya disease is heavily reliant upon a real-time understanding of cerebral hemodynamics. The application of FLOW 800 allows the surgeon to semiquantify the degree of perfusion to the cerebral cortex following extracranial-to-intracranial (EC-IC) bypass surgery. The authors present three illustrative cases demonstrating common intraoperative findings prior to and following anastomosis using FLOW 800. All patients were diagnosed by catheter angiogram with moyamoya disease and noninvasive imaging demonstrating hemispheric hypoperfusion. Superficial temporal artery (STA)\u2013to\u2013middle cerebral artery (MCA or M4) bypasses were performed to augment intracranial perfusion. The patients tolerated the procedures well and were discharged without event in stable neurological condition.<\/jats:p>\n                  <jats:p>\n                    The video can be found here:\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/stream.cadmore.media\/r10.3171\/2021.10.FOCVID21191\">https:\/\/stream.cadmore.media\/r10.3171\/2021.10.FOCVID21191<\/jats:ext-link>\n                  <\/jats:p>","DOI":"10.3171\/2021.10.focvid21191","type":"journal-article","created":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T10:23:00Z","timestamp":1641032580000},"page":"V16","source":"Crossref","is-referenced-by-count":3,"title":["Application of FLOW 800 in extracranial-to-intracranial bypass surgery for moyamoya disease"],"prefix":"10.3171","volume":"6","author":[{"given":"Benjamin","family":"Yim","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Gauden","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary K.","family":"Steinberg","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"r1","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"e186","DOI":"10.1016\/j.wneu.2018.09.195","article-title":"The application of FLOW 800 ICG videoangiography color maps for neurovascular surgery and intraoperative decision making","volume":"122","author":"Shah KJ","year":"2019","unstructured":"Shah KJ, Cohen-Gadol AA. The application of FLOW 800 ICG videoangiography color maps for neurovascular surgery and intraoperative decision making. World Neurosurg. 2019;122:e186\u2013e197.3029266810.1016\/j.wneu.2018.09.195"},{"issue":"1","key":"r2","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E8","DOI":"10.3171\/2018.4.FOCUS18207","article-title":"Editorial. The use of ICG videoangiography and FLOW 800 analysis","volume":"45","author":"Morcos JJ","year":"2018","unstructured":"Morcos JJ, Munich SA. Editorial. The use of ICG videoangiography and FLOW 800 analysis. Neurosurg Focus. 2018;45(1):E8.10.3171\/2018.4.FOCUS1820729961389"},{"issue":"5","key":"r3","series-title":"Oper Neurosurg (Hagerstown)","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1093\/ons\/opy154","article-title":"Intraoperative assessment of cortical perfusion after intracranial-to-intracranial and extracranial-to-intracranial bypass for complex cerebral aneurysms using Flow 800","volume":"16","author":"Rennert RC","year":"2019","unstructured":"Rennert RC, Strickland BA, Ravina K,  Intraoperative assessment of cortical perfusion after intracranial-to-intracranial and extracranial-to-intracranial bypass for complex cerebral aneurysms using Flow 800. Oper Neurosurg (Hagerstown). 2019;16(5):583\u2013592.10.1093\/ons\/opy154"},{"key":"r4","series-title":"Oxid Med Cell Longev","first-page":"8561609","article-title":"Evaluation of hemodynamic change by indocyanine green-FLOW 800 videoangiography mapping: prediction of hyperperfusion syndrome in patients with moyamoya disease","volume":"2020","author":"Zhang X","year":"2020","unstructured":"Zhang X, Ni W, Feng R,  Evaluation of hemodynamic change by indocyanine green-FLOW 800 videoangiography mapping: prediction of hyperperfusion syndrome in patients with moyamoya disease. Oxid Med Cell Longev. 2020;2020:8561609.32850003"},{"key":"r5","series-title":"Front Surg","doi-asserted-by":"publisher","first-page":"70","DOI":"10.3389\/fsurg.2019.00070","article-title":"Application of indocyanine green during arteriovenous malformation surgery: evidence, techniques, and practical pearls","volume":"6","author":"Foster CH","year":"2019","unstructured":"Foster CH, Morone PJ, Tomlinson SB, Cohen-Gadol AA. Application of indocyanine green during arteriovenous malformation surgery: evidence, techniques, and practical pearls. Front Surg. 2019;6:70.10.3389\/fsurg.2019.0007031921884"},{"key":"r1","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"e186","DOI":"10.1016\/j.wneu.2018.09.195","article-title":"The application of FLOW 800 ICG videoangiography color maps for neurovascular surgery and intraoperative decision making","volume":"122","author":"Shah KJ","year":"2019","unstructured":"Shah KJ, Cohen-Gadol AA. The application of FLOW 800 ICG videoangiography color maps for neurovascular surgery and intraoperative decision making. World Neurosurg. 2019;122:e186\u2013e197.3029266810.1016\/j.wneu.2018.09.195"},{"issue":"1","key":"r2","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E8","DOI":"10.3171\/2018.4.FOCUS18207","article-title":"Editorial. The use of ICG videoangiography and FLOW 800 analysis","volume":"45","author":"Morcos JJ","year":"2018","unstructured":"Morcos JJ, Munich SA. Editorial. The use of ICG videoangiography and FLOW 800 analysis. Neurosurg Focus. 2018;45(1):E8.10.3171\/2018.4.FOCUS1820729961389"},{"issue":"5","key":"r3","series-title":"Oper Neurosurg (Hagerstown)","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1093\/ons\/opy154","article-title":"Intraoperative assessment of cortical perfusion after intracranial-to-intracranial and extracranial-to-intracranial bypass for complex cerebral aneurysms using Flow 800","volume":"16","author":"Rennert RC","year":"2019","unstructured":"Rennert RC, Strickland BA, Ravina K,  Intraoperative assessment of cortical perfusion after intracranial-to-intracranial and extracranial-to-intracranial bypass for complex cerebral aneurysms using Flow 800. Oper Neurosurg (Hagerstown). 2019;16(5):583\u2013592.10.1093\/ons\/opy154"},{"key":"r4","series-title":"Oxid Med Cell Longev","first-page":"8561609","article-title":"Evaluation of hemodynamic change by indocyanine green-FLOW 800 videoangiography mapping: prediction of hyperperfusion syndrome in patients with moyamoya disease","volume":"2020","author":"Zhang X","year":"2020","unstructured":"Zhang X, Ni W, Feng R,  Evaluation of hemodynamic change by indocyanine green-FLOW 800 videoangiography mapping: prediction of hyperperfusion syndrome in patients with moyamoya disease. Oxid Med Cell Longev. 2020;2020:8561609.32850003"},{"key":"r5","series-title":"Front Surg","doi-asserted-by":"publisher","first-page":"70","DOI":"10.3389\/fsurg.2019.00070","article-title":"Application of indocyanine green during arteriovenous malformation surgery: evidence, techniques, and practical pearls","volume":"6","author":"Foster CH","year":"2019","unstructured":"Foster CH, Morone PJ, Tomlinson SB, Cohen-Gadol AA. Application of indocyanine green during arteriovenous malformation surgery: evidence, techniques, and practical pearls. Front Surg. 2019;6:70.10.3389\/fsurg.2019.0007031921884"}],"container-title":["Neurosurgical Focus: Video"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/neurosurg-focus-video\/6\/1\/article-pV16.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/neurosurg-focus-video\/6\/1\/article-pV16.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/neurosurg-focus-video\/6\/1\/article-pV16.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T23:22:27Z","timestamp":1782861747000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/neurosurg-focus-video\/6\/1\/article-pV16.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":10,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/2021.10.focvid21191","relation":{},"ISSN":["2643-5217"],"issn-type":[{"value":"2643-5217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]}}}