{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:42:46Z","timestamp":1792806166361,"version":"4.5.0"},"reference-count":19,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"\n OBJECTIVE<\/jats:title>\n M\u00e9ni\u00e8re\u2019s disease is an inner ear disorder classically characterized by fluctuating hearing loss, tinnitus, and aural fullness accompanied by episodic vertigo. While the pathogenesis of M\u00e9ni\u00e8re\u2019s remains under debate, histopathological analyses implicate endolymphatic sac dysfunction with inner ear fluid homeostatic dysregulation. Little is known about whether external impingement of the endolymphatic sac by tumors may present with M\u00e9ni\u00e8re\u2019s-like symptoms. The authors present a case series of 7 patients with posterior fossa meningiomas that involved the endolymphatic sac and new onset of M\u00e9ni\u00e8re\u2019s-like symptoms and review the literature on this rare clinical entity.<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n A retrospective review of patients undergoing resection of a posterior petrous meningioma was performed at the authors\u2019 institution. Inclusion criteria were age older than 18 years; patients presenting with M\u00e9ni\u00e8re\u2019s-like symptoms, including episodic vertigo, aural fullness, tinnitus, and\/or hearing loss; and tumor location overlying the endolymphatic sac.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n There were 7 cases of posterior petrous face meningiomas involving the vestibular aperture presenting with M\u00e9ni\u00e8re\u2019s-like symptoms. Imaging and intraoperative examination confirmed no cranial nerve VIII compression or labyrinthine artery involvement accounting for audiovestibular symptoms. Of the 7 patients in the series, 6 experienced significant improvement or resolution of their vertigo, and all 7 had improvement or resolution of their tinnitus after resection. Of the 5 patients who had preoperative hearing loss, 2 experienced improvement or resolution of their ipsilateral preoperative hearing deficit, whereas the other 3 had unchanged hearing loss compared to preoperative evaluation.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n Petrous face meningiomas overlying the endolymphatic sac can present with a M\u00e9ni\u00e8re\u2019s syndrome. Early recognition and microsurgical excision of these tumors is critical for resolution of most symptoms and stabilization of hearing loss.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2021.2.jns203259","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T04:11:34Z","timestamp":1633061494000},"page":"441-448","source":"Crossref","is-referenced-by-count":3,"title":["Posterior petrous face meningiomas presenting with M\u00e9ni\u00e8re\u2019s-like syndrome: a case series and review of the literature"],"prefix":"10.3171","volume":"136","author":[{"given":"Ramin A.","family":"Morshed","sequence":"first","affiliation":[{"name":"Departments of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole T.","family":"Jiam","sequence":"additional","affiliation":[{"name":"Otolaryngology\u2013Head and Neck Surgery, University of California, San Francisco, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaina J.","family":"Wang","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen T.","family":"Magill","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata M.","family":"Knoll","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Harvard Medical School, Massachusetts Eye and Ear, Boston, Massachusetts; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elliott D.","family":"Kozin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Harvard Medical School, Massachusetts Eye and Ear, Boston, Massachusetts; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip V.","family":"Theodosopoulos","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven W.","family":"Cheung","sequence":"additional","affiliation":[{"name":"Otolaryngology\u2013Head and Neck Surgery, University of California, San Francisco, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey D.","family":"Sharon","sequence":"additional","affiliation":[{"name":"Otolaryngology\u2013Head and Neck Surgery, University of California, San Francisco, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael W.","family":"McDermott","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery and"},{"name":"Division of Neurosurgery, Miami Neuroscience Institute, Miami, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"r1","series-title":"Nat Rev Dis Primers","doi-asserted-by":"publisher","first-page":"16028","DOI":"10.1038\/nrdp.2016.28","article-title":"Meniere\u2019s disease","volume":"2","author":"Nakashima T","year":"2016","unstructured":"Nakashima T, Pyykk\u00f6 I, Arroll MA, Meniere\u2019s disease. 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