{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:41:41Z","timestamp":1792806101974,"version":"4.5.0"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To test the hypothesis that intraplaque hemorrhage is a predictor of restenosis after carotid artery stenting (CAS), the association between intraplaque high-intensity signal (HIS) on time-of-flight MR angiography (TOF-MRA), as a marker of intraplaque hemorrhage, and restenosis after CAS was assessed in the present observational study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Consecutive patients who underwent initial CAS for atherosclerotic stenosis in the cervical internal carotid artery in the authors\u2019 department were enrolled. Of these, patients without preprocedural cervical TOF-MRA were excluded. Outcome measures were \u2265 50% restenosis, defined as a peak systolic velocity of &gt; 1.3 m\/sec; or occlusion and \u2265 70% restenosis, defined as a peak systolic velocity of &gt; 2.1 m\/sec; or occlusion on carotid duplex ultrasound.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Of 230 consecutive patients who underwent initial CAS, 22 without preprocedural cervical TOF-MRA were excluded. Of the remaining 208 patients (mean age 73 years; 33 women), 46 had intraplaque HIS. Ultrasound follow-up was not performed in 4 patients. The median follow-up duration was 3.2 years (interquartile range 1.7\u20135.1 years). During the follow-up period, 102 patients had \u2265 50% restenosis and 36 had \u2265 70% restenosis. Intraplaque HIS was significantly associated with increased risk of \u2265 50% restenosis (adjusted hazard ratio 2.18; 95% CI 1.28\u20133.68) and \u2265 70% restenosis (adjusted hazard ratio 3.12; 95% CI 1.32\u20137.52).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Intraplaque HIS on TOF-MRA was associated with increased risk of restenosis after CAS. The present results indicate that intraplaque hemorrhage is a predictor of restenosis after CAS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2021.4.jns21546","type":"journal-article","created":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T20:57:41Z","timestamp":1632517061000},"page":"1029-1034","source":"Crossref","is-referenced-by-count":7,"title":["Intraplaque high-intensity signal on time-of-flight magnetic resonance angiography and restenosis after carotid artery stenting"],"prefix":"10.3171","volume":"136","author":[{"given":"Keisuke","family":"Tokunaga","sequence":"first","affiliation":[{"name":"Department of Neuroendovascular Surgery, Clinical Research Institute, National Hospital Organization Kyushu Medical Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So","family":"Tokunaga","sequence":"additional","affiliation":[{"name":"Department of Neuroendovascular Surgery, Clinical Research Institute, National Hospital Organization Kyushu Medical Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenta","family":"Hara","sequence":"additional","affiliation":[{"name":"Department of Neuroendovascular Surgery, Clinical Research Institute, National Hospital Organization Kyushu Medical Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Yasaka","sequence":"additional","affiliation":[{"name":"Department of Cerebrovascular Medicine and Neurology, Clinical Research Institute, National Hospital Organization Kyushu Medical Center; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Cerebrovascular Medicine and Neurology, Clinical Research Institute, National Hospital Organization Kyushu Medical Center; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takanari","family":"Kitazono","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Tsumoto","sequence":"additional","affiliation":[{"name":"Department of Neuroendovascular Surgery, Clinical Research Institute, National Hospital Organization Kyushu Medical Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"15","key":"b1","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1056\/NEJMoa040127","article-title":"Protected carotid-artery stenting versus endarterectomy in high-risk patients","volume":"351","author":"Yadav JS","year":"2004","unstructured":"Yadav JS, Wholey MH, Kuntz RE,  Protected carotid-artery stenting versus endarterectomy in high-risk patients. N Engl J Med. 2004;351(15):1493\u20131501.1547021210.1056\/NEJMoa040127"},{"issue":"1","key":"b2","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1056\/NEJMoa0912321","article-title":"Stenting versus endarterectomy for treatment of carotid-artery stenosis","volume":"363","author":"Brott TG","year":"2010","unstructured":"Brott TG, Hobson RW II, Howard G,  Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med. 2010;363(1):11\u201323.10.1056\/NEJMoa091232120505173"},{"issue":"7","key":"b3","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1056\/NEJM199108153250701","article-title":"Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis","volume":"325","author":"North American Symptomatic Carotid Endarterectomy Trial Collaborators","year":"1991","unstructured":"North American Symptomatic Carotid Endarterectomy Trial Collaborators; Barnett HJM, Taylor DW, Haynes RB,  Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med. 1991;325(7):445\u2013453.10.1056\/NEJM1991081532507011852179"},{"issue":"18","key":"b4","series-title":"JAMA","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1001\/jama.1995.03520420037035","article-title":"Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study","volume":"273","author":"Walker MD","year":"1995","unstructured":"Walker MD, Marler JR, Goldstein M,  Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA. 1995;273(18):1421\u20131428.10.1001\/jama.1995.03520420037035"},{"issue":"9113","key":"b5","series-title":"Lancet","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1016\/S0140-6736(97)09292-1","article-title":"Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST)","volume":"351","author":"European Carotid Surgery Trialists\u2019 Collaborative Group","year":"1998","unstructured":"European Carotid Surgery Trialists\u2019 Collaborative Group. Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST). Lancet. 1998;351(9113):1379\u20131387.959340710.1016\/S0140-6736(97)09292-1"},{"issue":"20","key":"b6","series-title":"North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med","first-page":"1415","article-title":"Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis","volume":"339","author":"Barnett HJ","year":"1998","unstructured":"Barnett HJ, Taylor DW, Eliasziw M,  Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med. 1998;339(20):1415\u20131425."},{"issue":"9420","key":"b7","series-title":"Lancet","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1016\/S0140-6736(04)16146-1","article-title":"Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial","volume":"363","author":"Halliday A","year":"2004","unstructured":"Halliday A, Mansfield A, Marro J,  Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial. Lancet. 2004;363(9420):1491\u20131502.10.1016\/S0140-6736(04)16146-115135594"},{"issue":"10","key":"b8","series-title":"Lancet Neurol","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1016\/S1474-4422(08)70196-0","article-title":"Results of the Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) study to treat symptomatic stenoses at 2 years: a multinational, prospective, randomised trial","volume":"7","author":"Eckstein HH","year":"2008","unstructured":"Eckstein HH, Ringleb P, Allenberg JR,  Results of the Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) study to treat symptomatic stenoses at 2 years: a multinational, prospective, randomised trial. Lancet Neurol. 2008;7(10):893\u2013902.1877474610.1016\/S1474-4422(08)70196-0"},{"issue":"10","key":"b9","series-title":"Lancet Neurol","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/S1474-4422(09)70227-3","article-title":"Long-term risk of carotid restenosis in patients randomly assigned to endovascular treatment or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial","volume":"8","author":"Bonati LH","year":"2009","unstructured":"Bonati LH, Ederle J, McCabe DJ,  Long-term risk of carotid restenosis in patients randomly assigned to endovascular treatment or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial. Lancet Neurol. 2009;8(10):908\u2013917.10.1016\/S1474-4422(09)70227-3"},{"issue":"7","key":"b10","series-title":"Am J Cardiol","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/S0002-9149(03)00912-3","article-title":"Predictors of restenosis after successful carotid artery stenting","volume":"92","author":"Khan MA","year":"2003","unstructured":"Khan MA, Liu MW, Chio FL,  Predictors of restenosis after successful carotid artery stenting. Am J Cardiol. 2003;92(7):895\u2013897.10.1016\/S0002-9149(03)00912-314516904"},{"issue":"2","key":"b11","series-title":"Eur J Neurol","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1111\/j.1468-1331.2007.02026.x","article-title":"Postprocedural high-density lipoprotein cholesterol predicts carotid stent patency at 1 year","volume":"15","author":"Topakian R","year":"2008","unstructured":"Topakian R, Sonnberger M, Nussbaumer K,  Postprocedural high-density lipoprotein cholesterol predicts carotid stent patency at 1 year. Eur J Neurol. 2008;15(2):179\u2013184.1821788610.1111\/j.1468-1331.2007.02026.x"},{"issue":"9","key":"b12","series-title":"Lancet Neurol","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/S1474-4422(12)70159-X","article-title":"Restenosis after carotid artery stenting and endarterectomy: a secondary analysis of CREST, a randomised controlled trial","volume":"11","author":"Lal BK","year":"2012","unstructured":"Lal BK, Beach KW, Roubin GS,  Restenosis after carotid artery stenting and endarterectomy: a secondary analysis of CREST, a randomised controlled trial. Lancet Neurol. 2012;11(9):755\u2013763.10.1016\/S1474-4422(12)70159-X22857850"},{"issue":"2","key":"b13","series-title":"J Endovasc Ther","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1177\/1526602815626558","article-title":"Outcomes of 1000 Carotid Wallstent implantations: single-center experience","volume":"23","author":"Ronchey S","year":"2016","unstructured":"Ronchey S, Praquin B, Orrico M,  Outcomes of 1000 Carotid Wallstent implantations: single-center experience. J Endovasc Ther. 2016;23(2):267\u2013274.2680261210.1177\/1526602815626558"},{"issue":"4","key":"b14","series-title":"Cardiovasc Intervent Radiol","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1007\/s00270-015-1211-3","article-title":"The Effect of stent cell geometry on carotid stenting outcomes","volume":"39","author":"Alparslan B","year":"2016","unstructured":"Alparslan B, Nas OF, Eritmen UT,  The Effect of stent cell geometry on carotid stenting outcomes. Cardiovasc Intervent Radiol. 2016;39(4):507\u2013513.10.1007\/s00270-015-1211-326493821"},{"issue":"8","key":"b15","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"2144","DOI":"10.1161\/STROKEAHA.116.012650","article-title":"Predictors of restenosis following carotid angioplasty and stenting","volume":"47","author":"Zapata-Arriaza E","year":"2016","unstructured":"Zapata-Arriaza E, Moniche F, Gonz\u00e1lez A,  Predictors of restenosis following carotid angioplasty and stenting. Stroke. 2016;47(8):2144\u20132147.2732870110.1161\/STROKEAHA.116.012650"},{"issue":"11","key":"b16","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"3013","DOI":"10.1161\/STROKEAHA.118.024076","article-title":"Stent design, restenosis and recurrent stroke after carotid artery stenting in the International Carotid Stenting Study","volume":"50","author":"M\u00fcller MD","year":"2019","unstructured":"M\u00fcller MD, Gregson J, McCabe DJH,  Stent design, restenosis and recurrent stroke after carotid artery stenting in the International Carotid Stenting Study. Stroke. 2019;50(11):3013\u20133020.3154779810.1161\/STROKEAHA.118.024076"},{"issue":"5","key":"b17","series-title":"J Magn Reson Imaging","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1002\/jmri.1880060505","article-title":"Atherosclerosis of the carotid artery: evaluation by magnetic resonance angiography","volume":"6","author":"Wildy KS","year":"1996","unstructured":"Wildy KS, Yuan C, Tsuruda JS,  Atherosclerosis of the carotid artery: evaluation by magnetic resonance angiography. J Magn Reson Imaging. 1996;6(5):726\u2013732.10.1002\/jmri.18800605058890010"},{"issue":"6","key":"b18","series-title":"J Magn Reson Imaging","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1002\/jmri.21284","article-title":"High signal intensity halo around the carotid artery on maximum intensity projection images of time-of-flight MR angiography: a new sign for intraplaque hemorrhage","volume":"27","author":"Yim YJ","year":"2008","unstructured":"Yim YJ, Choe YH, Ko Y,  High signal intensity halo around the carotid artery on maximum intensity projection images of time-of-flight MR angiography: a new sign for intraplaque hemorrhage. J Magn Reson Imaging. 2008;27(6):1341\u20131346.1850475310.1002\/jmri.21284"},{"issue":"5","key":"b19","series-title":"J Diabetes Investig","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1111\/j.2040-1124.2010.00074.x","article-title":"Report of the committee on the classification and diagnostic criteria of diabetes mellitus","volume":"1","author":"Committee of the Japan Diabetes Society on the Diagnostic Criteria of Diabetes Mellitus","year":"2010","unstructured":"Committee of the Japan Diabetes Society on the Diagnostic Criteria of Diabetes Mellitus; Seino Y, Nanjo K, Tajima N,  Report of the committee on the classification and diagnostic criteria of diabetes mellitus. J Diabetes Investig. 2010;1(5):212\u2013228.10.1111\/j.2040-1124.2010.00074.x"},{"issue":"2","key":"b20","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1161\/01.STR.0000152333.75932.fe","article-title":"Restenosis after carotid angioplasty, stenting, or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS)","volume":"36","author":"McCabe DJ","year":"2005","unstructured":"McCabe DJ, Pereira AC, Clifton A,  Restenosis after carotid angioplasty, stenting, or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS). Stroke. 2005;36(2):281\u2013286.10.1161\/01.STR.0000152333.75932.fe"},{"issue":"11","key":"b21","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"3132","DOI":"10.1161\/STROKEAHA.111.615708","article-title":"High-intensity signal on time-of-flight magnetic resonance angiography indicates carotid plaques at high risk for cerebral embolism during stenting","volume":"42","author":"Yoshimura S","year":"2011","unstructured":"Yoshimura S, Yamada K, Kawasaki M,  High-intensity signal on time-of-flight magnetic resonance angiography indicates carotid plaques at high risk for cerebral embolism during stenting. Stroke. 2011;42(11):3132\u20133137.2186872510.1161\/STROKEAHA.111.615708"},{"issue":"3","key":"b22","series-title":"AJNR Am J Neuroradiol","doi-asserted-by":"publisher","first-page":"557","DOI":"10.3174\/ajnr.A3732","article-title":"Intraplaque high-intensity signal on 3D time-of-flight MR angiography is strongly associated with symptomatic carotid artery stenosis","volume":"35","author":"Gupta A","year":"2014","unstructured":"Gupta A, Baradaran H, Kamel H,  Intraplaque high-intensity signal on 3D time-of-flight MR angiography is strongly associated with symptomatic carotid artery stenosis. AJNR Am J Neuroradiol. 2014;35(3):557\u2013561.2400817010.3174\/ajnr.A3732"},{"issue":"1-2","key":"b23","series-title":"Cerebrovasc Dis","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1159\/000441094","article-title":"High-intensity signal in carotid plaque on routine 3D-TOF-MRA is a risk factor of ischemic stroke","volume":"41","author":"Yamada K","year":"2016","unstructured":"Yamada K, Kawasaki M, Yoshimura S,  High-intensity signal in carotid plaque on routine 3D-TOF-MRA is a risk factor of ischemic stroke. Cerebrovasc Dis. 2016;41(1-2):13\u201318.2658066710.1159\/000441094"},{"key":"b24","series-title":"J Neurol Sci","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.jns.2017.12.023","article-title":"High intensity signal in the plaque on routine 3D-TOF MRA is associated with ischemic stroke in the patients with low-grade carotid stenosis","volume":"385","author":"Yamada K","year":"2018","unstructured":"Yamada K, Yoshimura S, Shirakawa M,  High intensity signal in the plaque on routine 3D-TOF MRA is associated with ischemic stroke in the patients with low-grade carotid stenosis. J Neurol Sci. 2018;385:164\u2013167.10.1016\/j.jns.2017.12.023"},{"key":"b25","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.jocn.2019.01.033","article-title":"Asymptomatic moderate carotid artery stenosis with intraplaque hemorrhage: progression of degree of stenosis and new ischemic stroke","volume":"63","author":"Yamada K","year":"2019","unstructured":"Yamada K, Yoshimura S, Shirakawa M,  Asymptomatic moderate carotid artery stenosis with intraplaque hemorrhage: progression of degree of stenosis and new ischemic stroke. J Clin Neurosci. 2019;63:95\u201399.3073298310.1016\/j.jocn.2019.01.033"},{"issue":"1","key":"b26","series-title":"J Neurointerv Surg","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1136\/neurintsurg-2016-012419","article-title":"Diabetes mellitus and carotid artery plaques exhibiting high-intensity signals on MR angiography are related to increased platelet reactivity after carotid artery stenting","volume":"9","author":"Tsujimoto M","year":"2017","unstructured":"Tsujimoto M, Enomoto Y, Kokuzawa J, Iwama T. Diabetes mellitus and carotid artery plaques exhibiting high-intensity signals on MR angiography are related to increased platelet reactivity after carotid artery stenting. J Neurointerv Surg. 2017;9(1):106\u2013110.10.1136\/neurintsurg-2016-01241927370776"},{"issue":"6","key":"b27","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1873","DOI":"10.3171\/2016.4.JNS16349","article-title":"Carotid artery stenosis with a high-intensity signal plaque on time-of-flight magnetic resonance angiography and association with evidence of intraplaque hypoxia","volume":"126","author":"Ogata A","year":"2017","unstructured":"Ogata A, Kawashima M, Wakamiya T,  Carotid artery stenosis with a high-intensity signal plaque on time-of-flight magnetic resonance angiography and association with evidence of intraplaque hypoxia. J Neurosurg. 2017;126(6):1873\u20131878.2736723610.3171\/2016.4.JNS16349"},{"issue":"6","key":"b28","series-title":"Vascular","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1177\/1708538117706273","article-title":"Restenosis after carotid artery stenting","volume":"25","author":"Dai Z","year":"2017","unstructured":"Dai Z, Xu G. Restenosis after carotid artery stenting. Vascular. 2017;25(6):576\u2013586.2843631510.1177\/1708538117706273"},{"key":"b29","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.wneu.2018.07.005","article-title":"Optical frequency domain imaging evaluation of progressive carotid plaque and in-stent restenosis lesion with multiple neovascularizations","volume":"119","author":"Miura M","year":"2018","unstructured":"Miura M, Yamada K, Shindo S,  Optical frequency domain imaging evaluation of progressive carotid plaque and in-stent restenosis lesion with multiple neovascularizations. World Neurosurg. 2018;119:54\u201357.3001776510.1016\/j.wneu.2018.07.005"},{"issue":"11","key":"b30","series-title":"Arterioscler Thromb Vasc Biol","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1161\/hq1101.098230","article-title":"Angiogenesis, vascular endothelial growth factor and platelet-derived growth factor-BB expression, iron deposition, and oxidation-specific epitopes in stented human coronary arteries","volume":"21","author":"Br\u00e4sen JH","year":"2001","unstructured":"Br\u00e4sen JH, Kivel\u00e4 A, R\u00f6ser K,  Angiogenesis, vascular endothelial growth factor and platelet-derived growth factor-BB expression, iron deposition, and oxidation-specific epitopes in stented human coronary arteries. Arterioscler Thromb Vasc Biol. 2001;21(11):1720\u20131726.1170145610.1161\/hq1101.098230"},{"issue":"25","key":"b31","series-title":"Circulation","doi-asserted-by":"publisher","first-page":"2974","DOI":"10.1161\/01.CIR.0000019071.72887.BD","article-title":"Morphological predictors of restenosis after coronary stenting in humans","volume":"105","author":"Farb A","year":"2002","unstructured":"Farb A, Weber DK, Kolodgie FD,  Morphological predictors of restenosis after coronary stenting in humans. Circulation. 2002;105(25):2974\u20132980.10.1161\/01.CIR.0000019071.72887.BD12081990"},{"issue":"24","key":"b32","series-title":"Circulation","doi-asserted-by":"publisher","first-page":"2557","DOI":"10.1161\/CIRCULATIONAHA.113.007189","article-title":"Vasa vasorum in normal and diseased arteries","volume":"129","author":"Mulligan-Kehoe MJ","year":"2014","unstructured":"Mulligan-Kehoe MJ, Simons M. Vasa vasorum in normal and diseased arteries. Circulation. 2014;129(24):2557\u20132566.2493446310.1161\/CIRCULATIONAHA.113.007189"},{"issue":"21","key":"b33","series-title":"Circulation","doi-asserted-by":"publisher","first-page":"2768","DOI":"10.1161\/CIRCULATIONAHA.104.504167","article-title":"Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques: a high-resolution magnetic resonance imaging study","volume":"111","author":"Takaya N","year":"2005","unstructured":"Takaya N, Yuan C, Chu B,  Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques: a high-resolution magnetic resonance imaging study. Circulation. 2005;111(21):2768\u20132775.1591169510.1161\/CIRCULATIONAHA.104.504167"},{"issue":"7","key":"b34","series-title":"Lancet Neurol","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/S1474-4422(18)30195-9","article-title":"Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial","volume":"17","author":"Bonati LH","year":"2018","unstructured":"Bonati LH, Gregson J, Dobson J,  Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial. Lancet Neurol. 2018;17(7):587\u2013596.2986113910.1016\/S1474-4422(18)30195-9"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/136\/4\/article-p1029.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/136\/4\/article-p1029.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/136\/4\/article-p1029.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:07:55Z","timestamp":1792804075000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/136\/4\/article-p1029.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,1]]},"references-count":34,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/2021.4.jns21546","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,1]]}}}