{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:19:41Z","timestamp":1759936781958},"reference-count":40,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,1]]},"abstract":"\nOBJECTIVE<\/jats:title>\nMaximal safe ablation of target structures during magnetic resonance\u2013guided laser interstitial thermal therapy (MRgLiTT) is critical to achieving good seizure outcome in patients with mesial temporal lobe epilepsy (mTLE). The authors sought to determine whether intraoperative physiological variables are associated with ablation volume during MRgLiTT.<\/jats:p>\n<\/jats:sec>\n\nMETHODS<\/jats:title>\nPatients with mTLE who underwent MRgLiTT at our institution from 2014 to 2019 were retrospectively analyzed. Ablation volume was determined with volumetric analysis of intraoperative postablation MR images. Physiological parameters (systolic blood pressure [SBP], diastolic blood pressure [DBP], mean arterial pressure [MAP], end-tidal carbon dioxide [ETCO2<\/jats:sub>]) measured 40 minutes prior to ablation were analyzed. Univariate and multivariate regression analyses were performed to determine independent predictors of ablation volume.<\/jats:p>\n<\/jats:sec>\n\nRESULTS<\/jats:title>\nForty-four patients met the inclusion criteria. The median (interquartile range) ablation volume was 4.27 (2.92\u20135.89) cm3<\/jats:sup>, and median ablation energy was 7216 (6402\u20138784) J. The median MAP, SBP, DBP, and ETCO2<\/jats:sub> values measured during the 40-minute period leading up to ablation were 72.8 (66.2\u201381.5) mm Hg, 104.4 (96.4\u2013114.4) mm Hg, 62.4 (54.1\u201369.8) mm Hg, and 34.1 (32.0\u201336.2) mm Hg, respectively. In univariate analysis, only total laser energy (r = 0.464, p = 0.003) and 40-minute average ETCO2<\/jats:sub> (r = \u22120.388, p = 0.012) were significantly associated with ablation volume. In multivariate analysis, only ETCO2<\/jats:sub> \u2264 33 mm Hg (p = 0.001) was significantly associated with ablation volume.<\/jats:p>\n<\/jats:sec>\n\nCONCLUSIONS<\/jats:title>\nTotal ablation energy and ETCO2<\/jats:sub>, but not blood pressure, may significantly affect ablation volume in mTLE patients undergoing MRgLiTT. Mild hypocapnia was associated with increased extent of ablation. Intraoperative monitoring and modulation of ETCO2<\/jats:sub> may help improve extent of ablation, prediction of ablation volume, and potentially seizure outcome.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2021.9.jns211554","type":"journal-article","created":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T07:50:33Z","timestamp":1640937033000},"page":"427-433","source":"Crossref","is-referenced-by-count":3,"title":["Association of intraoperative end-tidal carbon dioxide level with ablation volume during magnetic resonance\u2013guided laser interstitial thermal therapy for mesial temporal lobe epilepsy"],"prefix":"10.3171","volume":"137","author":[{"given":"Brian Y.","family":"Hwang","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Eremiev","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adhith","family":"Palla","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Mampre","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serban","family":"Negoita","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohannes K.","family":"Tsehay","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Jae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"},{"name":"Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Coogan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joon Y.","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William S.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"4","key":"b1","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"E366","DOI":"10.1093\/neuros\/nyz556","article-title":"Magnetic resonance imaging-guided laser interstitial thermal therapy for epilepsy: systematic review of technique, indications, and outcomes","volume":"86","author":"Youngerman BE","year":"2020","unstructured":"Youngerman BE, Save AV, McKhann GM. Magnetic resonance imaging-guided laser interstitial thermal therapy for epilepsy: systematic review of technique, indications, and outcomes. Neurosurgery. 2020;86(4):E366\u2013E382.3198083110.1093\/neuros\/nyz556"},{"issue":"6","key":"b2","series-title":"Epilepsia","first-page":"1171","article-title":"Effects of surgical targeting in laser interstitial thermal therapy for mesial temporal lobe epilepsy: a multicenter study of 234 patients","volume":"60","author":"Wu C","year":"2019","unstructured":"Wu C, Jermakowicz WJ, Chakravorti S, Cajigas I, Sharan AD, Jagid JR, Effects of surgical targeting in laser interstitial thermal therapy for mesial temporal lobe epilepsy: a multicenter study of 234 patients. Epilepsia. 2019;60(6):1171\u20131183.31112302"},{"issue":"1","key":"b3","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1111\/epi.12860","article-title":"Better object recognition and naming outcome with MRI-guided stereotactic laser amygdalohippocampotomy for temporal lobe epilepsy","volume":"56","author":"Drane DL","year":"2015","unstructured":"Drane DL, Loring DW, Voets NL, Price M, Ojemann JG, Willie JT, Better object recognition and naming outcome with MRI-guided stereotactic laser amygdalohippocampotomy for temporal lobe epilepsy. Epilepsia. 2015;56(1):101\u2013113.2548963010.1111\/epi.12860"},{"issue":"5","key":"b4","series-title":"Oper Neurosurg (Hagerstown)","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1093\/ons\/opx029","article-title":"Visual deficit from laser interstitial thermal therapy for temporal lobe epilepsy: anatomical considerations","volume":"13","author":"Jermakowicz WJ","year":"2017","unstructured":"Jermakowicz WJ, Ivan ME, Cajigas I, Ribot R, Jusue-Torres I, Desai MB, Visual deficit from laser interstitial thermal therapy for temporal lobe epilepsy: anatomical considerations. Oper Neurosurg (Hagerstown). 2017;13(5):627\u2013633.10.1093\/ons\/opx029"},{"issue":"1","key":"b5","series-title":"Oper Neurosurg (Hagerstown)","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1093\/ons\/opaa264","article-title":"Laser interstitial thermal therapy case series: choosing the correct number of fibers depending on lesion size","volume":"20","author":"O\u2019Connor KP","year":"2020","unstructured":"O\u2019Connor KP, Palejwala AH, Milton CK, Lu VM, Glenn CA, Sughrue ME, Conner AK. Laser interstitial thermal therapy case series: choosing the correct number of fibers depending on lesion size. Oper Neurosurg (Hagerstown). 2020;20(1):18\u201323.10.1093\/ons\/opaa264"},{"key":"b6","series-title":"Seizure","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.seizure.2017.04.002","article-title":"Laser interstitial thermotherapy (LiTT) in epilepsy surgery","volume":"48","author":"Hoppe C","year":"2017","unstructured":"Hoppe C, Witt JA, Helmstaedter C, Gasser T, Vatter H, Elger CE. Laser interstitial thermotherapy (LiTT) in epilepsy surgery. Seizure. 2017;48:45\u201352.2841141410.1016\/j.seizure.2017.04.002"},{"issue":"7","key":"b7","series-title":"PLoS One","doi-asserted-by":"publisher","first-page":"e0199190","DOI":"10.1371\/journal.pone.0199190","article-title":"Ablation dynamics during laser interstitial thermal therapy for mesiotemporal epilepsy","volume":"13","author":"Jermakowicz WJ","year":"2018","unstructured":"Jermakowicz WJ, Cajigas I, Dan L, Guerra S, Sur S, D\u2019Haese PF, Ablation dynamics during laser interstitial thermal therapy for mesiotemporal epilepsy. PLoS One. 2018;13(7):e0199190.2997971710.1371\/journal.pone.0199190"},{"issue":"7","key":"b8","series-title":"Laser Phys","doi-asserted-by":"publisher","first-page":"075205","DOI":"10.1088\/1555-6611\/ab183b","article-title":"Prediction of laser-induced thermal damage with artificial neural networks","volume":"29","author":"Yildiz F","year":"2019","unstructured":"Yildiz F, \u00d6zdemir AT. Prediction of laser-induced thermal damage with artificial neural networks. Laser Phys. 2019;29(7):075205.10.1088\/1555-6611\/ab183b"},{"issue":"1","key":"b9","series-title":"Neurotherapeutics","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1007\/s13311-018-00693-1","article-title":"Optimizing trajectories for cranial laser interstitial thermal therapy using computer-assisted planning: a machine learning approach","volume":"16","author":"Li K","year":"2019","unstructured":"Li K, Vakharia VN, Sparks R, Fran\u00e7a LGS, Granados A, McEvoy AW, Optimizing trajectories for cranial laser interstitial thermal therapy using computer-assisted planning: a machine learning approach. Neurotherapeutics. 2019;16(1):182\u2013191.3052000310.1007\/s13311-018-00693-1"},{"issue":"7","key":"b10","series-title":"Int J Hyperthermia","doi-asserted-by":"publisher","first-page":"705","DOI":"10.3109\/02656736.2015.1055831","article-title":"A model evaluation study for treatment planning of laser-induced thermal therapy","volume":"31","author":"Fahrenholtz SJ","year":"2015","unstructured":"Fahrenholtz SJ, Moon TY, Franco M, Medina D, Danish S, Gowda A, A model evaluation study for treatment planning of laser-induced thermal therapy. Int J Hyperthermia. 2015;31(7):705\u2013714.10.3109\/02656736.2015.1055831"},{"key":"b11","series-title":"Front Oncol","doi-asserted-by":"publisher","first-page":"499","DOI":"10.3389\/fonc.2018.00499","article-title":"Management of intracranial metastatic disease with laser interstitial thermal therapy","volume":"8","author":"Salehi A","year":"2018","unstructured":"Salehi A, Kamath AA, Leuthardt EC, Kim AH. Management of intracranial metastatic disease with laser interstitial thermal therapy. Front Oncol. 2018;8:499.3043008310.3389\/fonc.2018.00499"},{"issue":"1","key":"b12","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1227\/NEU.0000000000000732","article-title":"Tissue ablation dynamics during magnetic resonance-guided, laser-induced thermal therapy","volume":"77","author":"Sun XR","year":"2015","unstructured":"Sun XR, Patel NV, Danish SF. Tissue ablation dynamics during magnetic resonance-guided, laser-induced thermal therapy. Neurosurgery. 2015;77(1):51\u201358.2608690810.1227\/NEU.0000000000000732"},{"issue":"6","key":"b13","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1227\/NEU.0000000000000343","article-title":"Real-time magnetic resonance-guided stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy","volume":"74","author":"Willie JT","year":"2014","unstructured":"Willie JT, Laxpati NG, Drane DL, Gowda A, Appin C, Hao C, Real-time magnetic resonance-guided stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy. Neurosurgery. 2014;74(6):569\u2013585.2461879710.1227\/NEU.0000000000000343"},{"issue":"4","key":"b14","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.3171\/2016.3.JNS152147","article-title":"Complication avoidance in laser interstitial thermal therapy: lessons learned","volume":"126","author":"Pruitt R","year":"2017","unstructured":"Pruitt R, Gamble A, Black K, Schulder M, Mehta AD. Complication avoidance in laser interstitial thermal therapy: lessons learned. J Neurosurg. 2017;126(4):1238\u20131245.2725783910.3171\/2016.3.JNS152147"},{"issue":"5","key":"b15","series-title":"Eur J Surg Oncol","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.ejso.2007.02.028","article-title":"Improving laser-induced thermotherapy of liver metastases\u2014effects of arterial microembolization and complete blood flow occlusion","volume":"33","author":"Ritz JP","year":"2007","unstructured":"Ritz JP, Lehmann KS, Zurbuchen U, Wacker F, Brehm F, Isbert C, Improving laser-induced thermotherapy of liver metastases\u2014effects of arterial microembolization and complete blood flow occlusion. Eur J Surg Oncol. 2007;33(5):608\u2013615.1740042110.1016\/j.ejso.2007.02.028"},{"issue":"1","key":"b16","series-title":"J Math Ind","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s13362-020-00085-1","article-title":"Identification of the blood perfusion rate for laser-induced thermotherapy in the liver","volume":"10","author":"Andres M","year":"2020","unstructured":"Andres M, Blauth S, Leith\u00e4user C, Siedow N. Identification of the blood perfusion rate for laser-induced thermotherapy in the liver. J Math Ind. 2020;10(1):17.10.1186\/s13362-020-00085-1"},{"key":"b17","series-title":"J Therm Biol","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.jtherbio.2018.10.021","article-title":"Computational study of photo-thermal ablation of large blood vessel embedded tumor using localized injection of gold nanoshells","volume":"78","author":"Paul A","year":"2018","unstructured":"Paul A, Paul A. Computational study of photo-thermal ablation of large blood vessel embedded tumor using localized injection of gold nanoshells. J Therm Biol. 2018;78:329\u2013342.3050965510.1016\/j.jtherbio.2018.10.021"},{"issue":"2","key":"b18","series-title":"Anesth Analg","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1213\/01.ane.0000295804.41688.8a","article-title":"Does hyperventilation improve operating condition during supratentorial craniotomy? A multicenter randomized crossover trial","volume":"106","author":"Gelb AW","year":"2008","unstructured":"Gelb AW, Craen RA, Rao GSU, Reddy KR, Megyesi J, Mohanty B, Does hyperventilation improve operating condition during supratentorial craniotomy? A multicenter randomized crossover trial. Anesth Analg. 2008;106(2):585\u2013594.1822732010.1213\/01.ane.0000295804.41688.8a"},{"issue":"4","key":"b19","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.3171\/2017.1.JNS162046","article-title":"Improved operative efficiency using a real-time MRI-guided stereotactic platform for laser amygdalohippocampotomy","volume":"128","author":"Ho AL","year":"2018","unstructured":"Ho AL, Sussman ES, Pendharkar AV, Le S, Mantovani A, Keebaugh AC, Improved operative efficiency using a real-time MRI-guided stereotactic platform for laser amygdalohippocampotomy. J Neurosurg. 2018;128(4):1165\u20131172.2866524910.3171\/2017.1.JNS162046"},{"issue":"3","key":"b20","series-title":"Ann Neurol","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1002\/ana.25180","article-title":"Stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy","volume":"83","author":"Gross RE","year":"2018","unstructured":"Gross RE, Stern MA, Willie JT, Fasano RE, Saindane AM, Soares BP, Stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy. Ann Neurol. 2018;83(3):575\u2013587.2942084010.1002\/ana.25180"},{"issue":"3","key":"b21","series-title":"Neuroimage","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1016\/j.neuroimage.2006.01.015","article-title":"User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability","volume":"31","author":"Yushkevich PA","year":"2006","unstructured":"Yushkevich PA, Piven J, Hazlett HC, Smith RG, Ho S, Gee JC, Gerig G. User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability. Neuroimage. 2006;31(3):1116\u20131128.1654596510.1016\/j.neuroimage.2006.01.015"},{"issue":"suppl 2","key":"b22","series-title":"Neurosurgery","first-page":"345","article-title":"The effects of anatomic variations on stereotactic laser amygdalohippocampectomy and a proposed protocol for trajectory planning","volume":"11","author":"Wu C","year":"2015","unstructured":"Wu C, Boorman DW, Gorniak RJ, Farrell CJ, Evans JJ, Sharan AD. The effects of anatomic variations on stereotactic laser amygdalohippocampectomy and a proposed protocol for trajectory planning. Neurosurgery. 2015;11(suppl 2):345\u2013357."},{"issue":"2","key":"b23","series-title":"Neuroimage","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1006\/nimg.1998.0395","article-title":"Cortical surface-based analysis. I. Segmentation and surface reconstruction","volume":"9","author":"Dale AM","year":"1999","unstructured":"Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage. 1999;9(2):179\u2013194.993126810.1006\/nimg.1998.0395"},{"key":"b24","series-title":"Front Surg","doi-asserted-by":"publisher","first-page":"64","DOI":"10.3389\/fsurg.2016.00064","article-title":"Stereotactic laser ablation for medically intractable epilepsy: the next generation of minimally invasive epilepsy surgery","volume":"3","author":"LaRiviere MJ","year":"2016","unstructured":"LaRiviere MJ, Gross RE. Stereotactic laser ablation for medically intractable epilepsy: the next generation of minimally invasive epilepsy surgery. Front Surg. 2016;3:64.2799512710.3389\/fsurg.2016.00064"},{"issue":"6","key":"b25","series-title":"J Cereb Blood Flow Metab","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1097\/01.WCB.0000067721.64998.F5","article-title":"Changes in human cerebral blood flow and cerebral blood volume during hypercapnia and hypocapnia measured by positron emission tomography","volume":"23","author":"Ito H","year":"2003","unstructured":"Ito H, Kanno I, Ibaraki M, Hatazawa J, Miura S. Changes in human cerebral blood flow and cerebral blood volume during hypercapnia and hypocapnia measured by positron emission tomography. J Cereb Blood Flow Metab. 2003;23(6):665\u2013670.1279671410.1097\/01.WCB.0000067721.64998.F5"},{"issue":"5","key":"b26","series-title":"Curr Opin Anaesthesiol","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1097\/ACO.0000000000000764","article-title":"Hyperventilation in neurological patients: from physiology to outcome evidence","volume":"32","author":"Zhang Z","year":"2019","unstructured":"Zhang Z, Guo Q, Wang E. Hyperventilation in neurological patients: from physiology to outcome evidence. Curr Opin Anaesthesiol. 2019;32(5):568\u2013573.3121171910.1097\/ACO.0000000000000764"},{"issue":"1","key":"b27","series-title":"Magn Reson Med","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1002\/mrm.22611","article-title":"Hippocampal blood flow in normal aging measured with arterial spin labeling at 3T","volume":"65","author":"Rusinek H","year":"2011","unstructured":"Rusinek H, Brys M, Glodzik L, Switalski R, Tsui WH, Haas F, Hippocampal blood flow in normal aging measured with arterial spin labeling at 3T. Magn Reson Med. 2011;65(1):128\u2013137.2093909410.1002\/mrm.22611"},{"issue":"6","key":"b28","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1111\/epi.13377","article-title":"Determinants of brain metabolism changes in mesial temporal lobe epilepsy","volume":"57","author":"Chassoux F","year":"2016","unstructured":"Chassoux F, Artiges E, Semah F, Desarnaud S, Laurent A, Landre E, Determinants of brain metabolism changes in mesial temporal lobe epilepsy. Epilepsia. 2016;57(6):907\u2013919.2706189610.1111\/epi.13377"},{"issue":"2","key":"b29","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1136\/jnnp.65.2.170","article-title":"Interictal regional slow activity in temporal lobe epilepsy correlates with lateral temporal hypometabolism as imaged with 18FDG PET: neurophysiological and metabolic implications","volume":"65","author":"Koutroumanidis M","year":"1998","unstructured":"Koutroumanidis M, Binnie CD, Elwes RDC, Polkey CE, Seed P, Alarcon G, Interictal regional slow activity in temporal lobe epilepsy correlates with lateral temporal hypometabolism as imaged with 18FDG PET: neurophysiological and metabolic implications. J Neurol Neurosurg Psychiatry. 1998;65(2):170\u2013176.970316610.1136\/jnnp.65.2.170"},{"issue":"6","key":"b30","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1001\/archneur.1993.00540060022011","article-title":"Interictal metabolic anatomy of mesial temporal lobe epilepsy","volume":"50","author":"Henry TR","year":"1993","unstructured":"Henry TR, Mazziotta JC, Engel J Jr. Interictal metabolic anatomy of mesial temporal lobe epilepsy. Arch Neurol. 1993;50(6):582\u2013589.850379410.1001\/archneur.1993.00540060022011"},{"issue":"7","key":"b31","series-title":"AJNR Am J Neuroradiol","first-page":"1334","article-title":"Detection of mesial temporal lobe hypoperfusion in patients with temporal lobe epilepsy by use of arterial spin labeled perfusion MR imaging","volume":"22","author":"Wolf RL","year":"2001","unstructured":"Wolf RL, Alsop DC, Levy-Reis I, Meyer PT, Maldjian JA, Gonzalez-Atavales J, Detection of mesial temporal lobe hypoperfusion in patients with temporal lobe epilepsy by use of arterial spin labeled perfusion MR imaging. AJNR Am J Neuroradiol. 2001;22(7):1334\u20131341.11498422"},{"issue":"6","key":"b32","series-title":"Semin Ultrasound CT MR","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1053\/j.sult.2007.09.005","article-title":"MR imaging of temporal lobe epilepsy","volume":"28","author":"Camacho DLA","year":"2007","unstructured":"Camacho DLA, Castillo M. MR imaging of temporal lobe epilepsy. Semin Ultrasound CT MR. 2007;28(6):424\u2013436.1807499910.1053\/j.sult.2007.09.005"},{"issue":"2","key":"b33","series-title":"Brain","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1093\/brain\/awx341","article-title":"Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study","volume":"141","author":"Whelan CD","year":"2018","unstructured":"Whelan CD, Altmann A, Bot\u00eda JA, Jahanshad N, Hibar DP, Absil J, Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study. Brain. 2018;141(2):391\u2013408.10.1093\/brain\/awx341"},{"issue":"5","key":"b34","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1161\/01.STR.3.5.566","article-title":"Hyperventilation and cerebral blood flow","volume":"3","author":"Raichle ME","year":"1972","unstructured":"Raichle ME, Plum F. Hyperventilation and cerebral blood flow. Stroke. 1972;3(5):566\u2013575.456913810.1161\/01.STR.3.5.566"},{"issue":"5","key":"b35","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1111\/epi.13715","article-title":"Laser thermal ablation for mesiotemporal epilepsy: analysis of ablation volumes and trajectories","volume":"58","author":"Jermakowicz WJ","year":"2017","unstructured":"Jermakowicz WJ, Kanner AM, Sur S, Bermudez C, D\u2019Haese PF, Kolcun JPG, Laser thermal ablation for mesiotemporal epilepsy: analysis of ablation volumes and trajectories. Epilepsia. 2017;58(5):801\u2013810.2824459010.1111\/epi.13715"},{"key":"b36","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.wneu.2020.07.194","article-title":"Surgical outcomes of laser interstitial thermal therapy for temporal lobe epilepsy: systematic review and meta-analysis","volume":"143","author":"Kerezoudis P","year":"2020","unstructured":"Kerezoudis P, Parisi V, Marsh WR, Kaufman TJ, Lehman VT, Worrell GA, Surgical outcomes of laser interstitial thermal therapy for temporal lobe epilepsy: systematic review and meta-analysis. World Neurosurg. 2020;143:527\u2013536.e3.3275051110.1016\/j.wneu.2020.07.194"},{"issue":"2","key":"b37","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1111\/epi.13284","article-title":"Laser interstitial thermal therapy for medically intractable mesial temporal lobe epilepsy","volume":"57","author":"Kang JY","year":"2016","unstructured":"Kang JY, Wu C, Tracy J, Lorenzo M, Evans J, Nei M, Laser interstitial thermal therapy for medically intractable mesial temporal lobe epilepsy. Epilepsia. 2016;57(2):325\u2013334.2669796910.1111\/epi.13284"},{"issue":"6","key":"b38","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"2055","DOI":"10.3171\/2018.2.JNS171873","article-title":"Laser ablation for mesial temporal epilepsy: a multi-site, single institutional series","volume":"130","author":"Grewal SS","year":"2018","unstructured":"Grewal SS, Zimmerman RS, Worrell G, Brinkmann BH, Tatum WO, Crepeau AZ, Laser ablation for mesial temporal epilepsy: a multi-site, single institutional series. J Neurosurg. 2018;130(6):2055\u20132062.10.3171\/2018.2.JNS171873"},{"issue":"4","key":"b39","series-title":"Stereotact Funct Neurosurg","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1159\/000502701","article-title":"Mechanisms and risk factors contributing to visual field deficits following stereotactic laser amygdalohippocampotomy","volume":"97","author":"Voets NL","year":"2019","unstructured":"Voets NL, Alvarez I, Qiu D, Leatherday C, Willie JT, Sotiropoulos S, Mechanisms and risk factors contributing to visual field deficits following stereotactic laser amygdalohippocampotomy. Stereotact Funct Neurosurg. 2019;97(4):255\u2013265.3161874910.1159\/000502701"},{"issue":"3","key":"b40","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1007\/s00381-019-04051-0","article-title":"Magnetic resonance-guided laser interstitial thermal therapy for the treatment of non-lesional insular epilepsy in pediatric patients: thermal dynamic and volumetric factors influencing seizure outcomes","volume":"35","author":"Alexander H","year":"2019","unstructured":"Alexander H, Cobourn K, Fayed I, Depositario-Cabacar D, Keating RF, Gaillard WD, Oluigbo CO. Magnetic resonance-guided laser interstitial thermal therapy for the treatment of non-lesional insular epilepsy in pediatric patients: thermal dynamic and volumetric factors influencing seizure outcomes. Childs Nerv Syst. 2019;35(3):453\u2013461.3062777110.1007\/s00381-019-04051-0"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/137\/2\/article-p427.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/137\/2\/article-p427.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/137\/2\/article-p427.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T11:04:56Z","timestamp":1716030296000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/137\/2\/article-p427.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,1]]},"references-count":40,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3171\/2021.9.jns211554","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,1]]}}}