{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T02:25:52Z","timestamp":1794018352836,"version":"4.8.0"},"reference-count":33,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"\n OBJECTIVE<\/jats:title>\n The objective of this study was to propose a new skull outline\u2013based method to objectively quantify complex 3D skull shapes and frontal and supraorbital retrusion in metopic craniosynostosis using 3D photogrammetry.<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n \n A standard section from 3D photogrammetry, which represents the trigonocephalic shape, was used in this study. From the midpoint of the area of this section, half diagonals were calculated to the skull outline at 5\u00b0 increments in the anterior half of the head. These half diagonals were used to create a sinusoidal curve, and the area under the sinusoidal curve (AUC) was used to represent the mathematical expression of the trigonocephalic head shape. The AUC from 0\u00b0 to 180\u00b0 (90\u00b0 from the midline to each side) was calculated and is referred to as AUC\n 0\u2192180<\/jats:sub>\n . The AUC from 60\u00b0 to 120\u00b0 (30\u00b0 from the midline to each side) was also calculated and is referred to as AUC\n 60\u2192120<\/jats:sub>\n . A total of 24 patients who underwent endoscopic strip craniectomy and 13 age- and sex-matched controls were included in the study. The AUC values obtained in patients at different time points and controls were analyzed.\n <\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n \n The mean preoperative AUC\n 60\u2192120<\/jats:sub>\n and AUC\n 0\u2192180<\/jats:sub>\n in the patients were significantly lower than those in control individuals. The increase in both AUC\n 60\u2192120<\/jats:sub>\n and AUC\n 0\u2192180<\/jats:sub>\n values is statistically significant at the discontinuation of helmet therapy and at final follow-up. Receiver operating characteristic curve analysis indicated that AUC\n 60\u2192120<\/jats:sub>\n is a more accurate classifier than AUC\n 0\u2192180<\/jats:sub>\n .\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n The proposed method objectively quantifies complex head shape and frontal retrusion in patients with metopic craniosynostosis and provides a quantitative measure for follow-up after surgical treatment. It avoids ionizing radiation exposure.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2022.1.peds21553","type":"journal-article","created":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T03:22:35Z","timestamp":1646968955000},"page":"650-658","source":"Crossref","is-referenced-by-count":5,"title":["A new method for quantification of frontal retrusion and complex skull shape in metopic craniosynostosis: a pilot study of a new outcome measure for endoscopic strip craniectomy"],"prefix":"10.3171","volume":"29","author":[{"given":"Mustafa","family":"Sakar","sequence":"first","affiliation":[{"name":"Marmara University, School of Medicine, Department of Neurosurgery, Istanbul, Turkey;"},{"name":"Marmara University, Institute of Neurological Sciences, Istanbul, Turkey;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Haidar","sequence":"additional","affiliation":[{"name":"Marmara University, School of Medicine, Istanbul, Turkey; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zcan","family":"S\u00f6nmez","sequence":"additional","affiliation":[{"name":"Marmara University, School of Medicine, Department of Neurosurgery, Istanbul, Turkey;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onur","family":"Erdo\u011fan","sequence":"additional","affiliation":[{"name":"Marmara University, School of Medicine, Department of Neurosurgery, Istanbul, Turkey;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00fclent","family":"Sa\u00e7ak","sequence":"additional","affiliation":[{"name":"Marmara University, School of Medicine, Plastic and Reconstructive Surgery, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya\u015far","family":"Bayri","sequence":"additional","affiliation":[{"name":"Marmara University, School of Medicine, Department of Neurosurgery, Istanbul, Turkey;"},{"name":"Marmara University, Institute of Neurological Sciences, Istanbul, Turkey;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Da\u011f\u00e7\u0131nar","sequence":"additional","affiliation":[{"name":"Marmara University, School of Medicine, Department of Neurosurgery, Istanbul, Turkey;"},{"name":"Marmara University, Institute of Neurological Sciences, Istanbul, Turkey;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"1","key":"b1","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"21","DOI":"10.3171\/2009.3.PEDS08355","article-title":"Evolution in the frequency of nonsyndromic craniosynostosis","volume":"4","author":"Di Rocco F","year":"2009","unstructured":"Di Rocco F, Arnaud E, Renier D. 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