{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T04:45:51Z","timestamp":1778042751947,"version":"3.51.4"},"reference-count":27,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>Stereoelectroencephalography (SEEG) is designed to target distributed cortical networks responsible for electroclinical seizure syndrome and to enable localization of the site of seizure onset in patients with intractable epilepsy. When the preimplantation hypothesis invokes the bilateral mesial frontal lobes, sampling of several deep-seated cortical sites in both hemispheres is required. In this study, the authors have demonstrated the feasibility of sampling bihemispheric areas with intentional implantation of an SEEG electrode crossing the midline (SECM) for sampling the cortex on both sides of the interhemispheric fissure.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>An analysis of 231 consecutive SEEG procedures over 8 years was used to identify instances of bihemispheric sampling by using the transmidline SEEG technique.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>The authors identified 53 SEEG cases, with a total of 126 electrodes that crossed the interhemispheric fissure; all were in the frontal lobes. Eighty-three electrodes targeted the cingulate gyrus (18 rostral, 43 anterior, and 22 middle), 31 targeted the posterior orbitofrontal region, 8 sampled the medial prefrontal cortex, and 4 targeted nodular heterotopia around the frontal horns. The ictal onset zone was localized to the frontal lobe in 16 cases. SECM isolated interictal and ictal activity in the contralateral hemisphere in 6 cases and independent bihemispheric seizure activity in 2 cases. No hemorrhagic or infectious complications were noted in any of these cases.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>Based on this extensive experience of bihemispheric sampling, the authors concluded that this technique is safe and effective. In this series, SECM showed contralateral interictal and\/or ictal epileptiform activity in 8 (15%) cases, and 9 (16%) cases (with unilateral implantation) had sufficient data to discard contralateral involvement, contributing to support of the epileptogenic network. SECM may reduce the number of electrodes used to sample bilateral mesial frontal or orbitofrontal cortices, and such an approach may lower the risk of hemorrhage and costs.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2022.11.jns221144","type":"journal-article","created":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T10:37:11Z","timestamp":1672396631000},"page":"229-237","source":"Crossref","is-referenced-by-count":5,"title":["Safety and efficacy of bihemispheric sampling via transmidline stereoelectroencephalography"],"prefix":"10.3171","volume":"139","author":[{"given":"Carlos E.","family":"Restrepo","sequence":"first","affiliation":[{"name":"Vivian L. Smith Department of Neurosurgery, McGovern Medical School at University of Texas Health Science Center at Houston;"},{"name":"Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston;"},{"name":"Memorial Hermann Hospital, Texas Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Balaguera","sequence":"additional","affiliation":[{"name":"Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston;"},{"name":"Department of Neurology, McGovern Medical School at University of Texas Health Science Center at Houston; and"},{"name":"Memorial Hermann Hospital, Texas Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen A.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston;"},{"name":"Department of Neurology, McGovern Medical School at University of Texas Health Science Center at Houston; and"},{"name":"Memorial Hermann Hospital, Texas Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Johnson","sequence":"additional","affiliation":[{"name":"Vivian L. Smith Department of Neurosurgery, McGovern Medical School at University of Texas Health Science Center at Houston;"},{"name":"Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuria","family":"Lacuey","sequence":"additional","affiliation":[{"name":"Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston;"},{"name":"Department of Neurology, McGovern Medical School at University of Texas Health Science Center at Houston; and"},{"name":"Memorial Hermann Hospital, Texas Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandipan","family":"Pati","sequence":"additional","affiliation":[{"name":"Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston;"},{"name":"Department of Neurology, McGovern Medical School at University of Texas Health Science Center at Houston; and"},{"name":"Memorial Hermann Hospital, Texas Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Harris","sequence":"additional","affiliation":[{"name":"Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston;"},{"name":"Department of Neurology, McGovern Medical School at University of Texas Health Science Center at Houston; and"},{"name":"Memorial Hermann Hospital, Texas Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samden D.","family":"Lhatoo","sequence":"additional","affiliation":[{"name":"Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston;"},{"name":"Department of Neurology, McGovern Medical School at University of Texas Health Science Center at Houston; and"},{"name":"Memorial Hermann Hospital, Texas Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitin","family":"Tandon","sequence":"additional","affiliation":[{"name":"Vivian L. Smith Department of Neurosurgery, McGovern Medical School at University of Texas Health Science Center at Houston;"},{"name":"Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston;"},{"name":"Memorial Hermann Hospital, Texas Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"6","key":"b1","series-title":"JAMA Neurol","first-page":"672","article-title":"Analysis of morbidity and outcomes associated with use of subdural grids vs stereoelectroencephalography in patients with intractable epilepsy","volume":"76","author":"Tandon N","year":"2019","unstructured":"Tandon N, Tong BA, Friedman ER,  Analysis of morbidity and outcomes associated with use of subdural grids vs stereoelectroencephalography in patients with intractable epilepsy. JAMA Neurol. 2019;76(6):672\u2013681.30830149"},{"key":"b2","series-title":"World Neurosurg","first-page":"1","article-title":"SEEG, happy anniversary!","volume":"85","author":"Cardinale F","year":"2016","unstructured":"Cardinale F, Gonz\u00e1lez-Mart\u00ednez J, Lo Russo G. SEEG, happy anniversary!. World Neurosurg. 2016;85:1\u20132.26679262"},{"issue":"2","key":"b3","series-title":"Epilepsia","first-page":"323","article-title":"Stereoelectroencephalography in the \"difficult to localize\" refractory focal epilepsy: early experience from a North American epilepsy center","volume":"54","author":"Gonzalez-Martinez J","year":"2013","unstructured":"Gonzalez-Martinez J, Bulacio J, Alexopoulos A, Jehi L, Bingaman W, Najm I. Stereoelectroencephalography in the \"difficult to localize\" refractory focal epilepsy: early experience from a North American epilepsy center. Epilepsia. 2013;54(2):323\u2013330.23016576"},{"issue":"1","key":"b4","series-title":"Neurosurg Clin N Am","first-page":"97","article-title":"Stereo-encephalography versus subdural electrodes for seizure localization","volume":"27","author":"Podkorytova I","year":"2016","unstructured":"Podkorytova I, Hoes K, Lega B. Stereo-encephalography versus subdural electrodes for seizure localization. Neurosurg Clin N Am. 2016;27(1):97\u2013109.26615112"},{"issue":"4","key":"b5","series-title":"Electroencephalogr Clin Neurophysiol","first-page":"481","article-title":"The electroencephalogram in parasagittal lesions","volume":"4","author":"T\u00fckel K","year":"1952","unstructured":"T\u00fckel K, Jasper H. The electroencephalogram in parasagittal lesions. Electroencephalogr Clin Neurophysiol. 1952;4(4):481\u2013494.12998596"},{"issue":"6","key":"b6","series-title":"J Clin Neurophysiol","first-page":"483","article-title":"Stereo-EEG implantation strategy","volume":"33","author":"Kalamangalam GP","year":"2016","unstructured":"Kalamangalam GP, Tandon N. Stereo-EEG implantation strategy. J Clin Neurophysiol. 2016;33(6):483\u2013489.27918343"},{"key":"b7","series-title":"A Practical Approach to Stereo EEG.","first-page":"409","article-title":"Stereo EEG-guided resections: method and technique","author":"Gonzalez-Martinez JA","year":"2020","unstructured":"Gonzalez-Martinez JA, Gersey ZC. Stereo EEG-guided resections: method and technique. In: Schuele SU, ed.A Practical Approach to Stereo EEG.. Springer; 2020:409\u2013420."},{"issue":"3","key":"b8","series-title":"Epilepsia","first-page":"571","article-title":"Risk analysis of hemorrhage in stereo-electroencephalography procedures","volume":"60","author":"McGovern RA","year":"2019","unstructured":"McGovern RA, Ruggieri P, Bulacio J, Najm I, Bingaman WE, Gonzalez-Martinez JA. Risk analysis of hemorrhage in stereo-electroencephalography procedures. Epilepsia. 2019;60(3):571\u2013580.30746685"},{"issue":"4","key":"b9","series-title":"Epilepsia","first-page":"491","article-title":"Frontal lobe seizure propagation: scalp and subdural EEG studies","volume":"42","author":"Blume WT","year":"2001","unstructured":"Blume WT, Ociepa D, Kander V. Frontal lobe seizure propagation: scalp and subdural EEG studies. Epilepsia. 2001;42(4):491\u2013503.11440344"},{"issue":"5","key":"b10","series-title":"Epilepsia","first-page":"479","article-title":"Human hippocampal seizure spread studied by depth and subdural recording: the hippocampal commissure","volume":"28","author":"Spencer SS","year":"1987","unstructured":"Spencer SS, Williamson PD, Spencer DD, Mattson RH. Human hippocampal seizure spread studied by depth and subdural recording: the hippocampal commissure. Epilepsia. 1987;28(5):479\u2013489.3653050"},{"issue":"6","key":"b11","series-title":"Epilepsia","first-page":"822","article-title":"Role of the frontal lobes in the propagation of mesial temporal lobe seizures","volume":"32","author":"Lieb JP","year":"1991","unstructured":"Lieb JP, Dasheiff RM, Engel J Jr. Role of the frontal lobes in the propagation of mesial temporal lobe seizures. Epilepsia. 1991;32(6):822\u2013837.1743154"},{"issue":"1","key":"b12","series-title":"J Neurosurg","first-page":"245","article-title":"Oblique trajectory angles in robotic stereoelectroencephalography","volume":"135","author":"Rollo PS","year":"2021","unstructured":"Rollo PS, Rollo MJ, Zhu P, Woolnough O, Tandon N. Oblique trajectory angles in robotic stereoelectroencephalography. J Neurosurg. 2021;135(1):245\u2013254."},{"issue":"suppl 2","key":"b13","series-title":"Epileptic Disord","first-page":"S16","article-title":"The Bancaud and Talairach view on the epileptogenic zone: a working hypothesis","volume":"8","author":"Kahane P","year":"2006","unstructured":"Kahane P, Landr\u00e9 E, Minotti L, Francione S, Ryvlin P. The Bancaud and Talairach view on the epileptogenic zone: a working hypothesis. Epileptic Disord. 2006;8(suppl 2):S16\u2013S26."},{"key":"b14","series-title":"Prog Neurol Surg","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1159\/000394343","article-title":"Stereotaxic approach to epilepsy","volume":"5","author":"Talairach J","year":"1973","unstructured":"Talairach J, Bancaud J. Stereotaxic approach to epilepsy. Prog Neurol Surg. 1973;5:297\u2013354."},{"key":"b15","series-title":"Confin Neurol","first-page":"328","article-title":"Functional stereotaxic exploration of epilepsy","volume":"22","author":"Talairach J","year":"1962","unstructured":"Talairach J, Bancaud J, Bonis A, Szikla G, Tournoux P. Functional stereotaxic exploration of epilepsy. Confin Neurol. 1962;22:328\u2013331.13984743"},{"issue":"4","key":"b16","series-title":"J Neurosurg","first-page":"1147","article-title":"Indications, technique, and safety profile of insular stereoelectroencephalography electrode implantation in medically intractable epilepsy","volume":"128","author":"Alomar S","year":"2018","unstructured":"Alomar S, Mullin JP, Smithason S, Gonzalez-Martinez J. Indications, technique, and safety profile of insular stereoelectroencephalography electrode implantation in medically intractable epilepsy. J Neurosurg. 2018;128(4):1147\u20131157.28621621"},{"issue":"1","key":"b17","series-title":"Neurophysiol Clin","first-page":"25","article-title":"Planning and management of SEEG","volume":"48","author":"Chassoux F","year":"2018","unstructured":"Chassoux F, Navarro V, Catenoix H, Valton L, Vignal JP. Planning and management of SEEG. Neurophysiol Clin. 2018;48(1):25\u201337.29254835"},{"issue":"2","key":"b18","series-title":"Epilepsia","first-page":"264","article-title":"Frontal lobe seizures: from clinical semiology to localization","volume":"55","author":"Bonini F","year":"2014","unstructured":"Bonini F, McGonigal A, Tr\u00e9buchon A,  Frontal lobe seizures: from clinical semiology to localization. Epilepsia. 2014;55(2):264\u2013277.24372328"},{"issue":"1","key":"b19","series-title":"Epilepsia","first-page":"107","article-title":"Localization yield and seizure outcome in patients undergoing bilateral SEEG exploration","volume":"60","author":"Steriade C","year":"2019","unstructured":"Steriade C, Martins W, Bulacio J,  Localization yield and seizure outcome in patients undergoing bilateral SEEG exploration. Epilepsia. 2019;60(1):107\u2013120.30588603"},{"key":"b20","series-title":"Handb Clin Neurol","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/B978-0-12-804281-6.00006-9","article-title":"The anatomy of the human frontal lobe","volume":"163","author":"Catani M","year":"2019","unstructured":"Catani M. The anatomy of the human frontal lobe. Handb Clin Neurol. 2019;163:95\u2013122.31590750"},{"issue":"3","key":"b21","series-title":"Nat Neurosci","first-page":"272","article-title":"Humans and great apes share a large frontal cortex","volume":"5","author":"Semendeferi K","year":"2002","unstructured":"Semendeferi K, Lu A, Schenker N, Damasio H. Humans and great apes share a large frontal cortex. Nat Neurosci. 2002;5(3):272\u2013276."},{"issue":"5","key":"b22","series-title":"J Clin Neurosci","first-page":"593","article-title":"Frontal lobe epilepsy","volume":"18","author":"Beleza P","year":"2011","unstructured":"Beleza P, Pinho J. Frontal lobe epilepsy. J Clin Neurosci. 2011;18(5):593\u2013600.21349720"},{"issue":"4","key":"b23","series-title":"Epileptic Disord","first-page":"223","article-title":"Frontal lobe epilepsy","volume":"6","author":"Kellinghaus C","year":"2004","unstructured":"Kellinghaus C, L\u00fcders HO. Frontal lobe epilepsy. Epileptic Disord. 2004;6(4):223\u2013239.15634619"},{"issue":"2","key":"b24","series-title":"Cortex","first-page":"144","article-title":"Epilepsy and the frontal lobes","volume":"48","author":"O\u2019Muircheartaigh J","year":"2012","unstructured":"O\u2019Muircheartaigh J, Richardson MP. Epilepsy and the frontal lobes. Cortex. 2012;48(2):144\u2013155.22176870"},{"key":"b25","series-title":"Principles of Neuro-Oncology","article-title":"Microsurgical anatomy of the interhemispheric fissure complex: an anatomical-functional model in brain tumors","author":"Monroy-Sosa A","year":"2021","unstructured":"Monroy-Sosa A, Chakravarthi SS, Epping A, Santiago-Ramirez N, Ayala-Arcipreste A. Microsurgical anatomy of the interhemispheric fissure complex: an anatomical-functional model in brain tumors. In: Monroy-Sosa A, Chakravarthi SS, de la Garza-Salazar J, , eds.Principles of Neuro-Oncology. Springer; 2021."},{"issue":"3","key":"b26","series-title":"Epilepsia","first-page":"386","article-title":"Is SEEG safe? A systematic review and meta-analysis of stereo-electroencephalography-related complications","volume":"57","author":"Mullin JP","year":"2016","unstructured":"Mullin JP, Shriver M, Alomar S,  Is SEEG safe? A systematic review and meta-analysis of stereo-electroencephalography-related complications. Epilepsia. 2016;57(3):386\u2013401."},{"issue":"6","key":"b27","series-title":"Epilepsia","first-page":"921","article-title":"Accuracy of intracranial electrode placement for stereoencephalography: a systematic review and meta-analysis","volume":"58","author":"Vakharia VN","year":"2017","unstructured":"Vakharia VN, Sparks R, O\u2019Keeffe AG,  Accuracy of intracranial electrode placement for stereoencephalography: a systematic review and meta-analysis. Epilepsia. 2017;58(6):921\u2013932.28261785"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/139\/1\/article-p229.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/139\/1\/article-p229.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/139\/1\/article-p229.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T10:47:49Z","timestamp":1716029269000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/139\/1\/article-p229.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,1]]},"references-count":27,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/2022.11.jns221144","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,1]]}}}