{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T21:25:56Z","timestamp":1794000356033,"version":"4.8.0"},"reference-count":33,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>The authors compared the Contour Neurovascular System (Contour) with the Woven EndoBridge (WEB) device for the treatment of wide-necked cerebral aneurysms at a bifurcation or sidewall.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>Prospective clinical and radiological data were collected for all patients treated with either the Contour or WEB at a tertiary university hospital from May 2018 to June 2022.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>In patients who had at least 3 months of follow-up data available (median patient age 60.0 [IQR 51.8\u201367.0] years, male\/female ratio 1:1.4), the authors compared 40 aneurysms in 34 patients treated with the Contour and 30 aneurysms in 30 patients treated with the WEB. Overall, 26 middle cerebral artery, 24 anterior communicating artery, 9 basilar artery tip, 4 posterior communicating artery, 4 internal carotid artery, 1 anterior cerebral artery, 1 posterior inferior cerebellar artery, and 1 superior cerebellar artery aneurysm were treated. In the Contour cohort, complete occlusion at last follow-up was achieved for 30 aneurysms (75%) and a small neck remnant was seen in 6 aneurysms (15%), summing up to an adequate occlusion rate of 90%. One aneurysm (2.5%) had to be retreated, and 1 symptomatic thromboembolic event (2.5%) was observed with complete remission at discharge. Three adjunctive stents (10%) had to be used due to branch occlusion. In the WEB cohort, adequate occlusion was also seen in 90% of aneurysms (complete occlusion in 19 [63.3%] and remnant neck in 8 [26.7%], with a retreatment rate of 20%). Four WEBs (13.3%) needed additional stent placement due to device protrusion into a branch, 2 asymptomatic thromboembolic events (6.7%) were noted, and 1 major ischemic event (3.3%) due to M2 occlusion was noted. One patient treated with the WEB died between follow-ups of causes unrelated to the aneurysm, treatment, or device. Time from first measurement to deployment and thus total treatment time was significantly shorter in the Contour group (p = 0.004), regardless of whether a prior angiogram was available for aneurysm measurement and device sizing.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>Results for the Contour were promising, although longer follow-up is necessary to draw more solid conclusions on the utility and risk profile of this new device compared with the already widely used WEB device. Adequate occlusion at last follow-up was the same for both devices, whereas the probability of complete occlusion at last follow-up was significantly higher for the Contour, and the WEB showed a significantly higher retreatment rate. Median deployment times were significantly shorter with the Contour than the WEB.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2022.12.jns222268","type":"journal-article","created":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T15:39:31Z","timestamp":1674833971000},"page":"563-572","source":"Crossref","is-referenced-by-count":25,"title":["Comparison of the Contour Neurovascular System and Woven EndoBridge device for treatment of wide-necked cerebral aneurysms at a bifurcation or sidewall"],"prefix":"10.3171","volume":"139","author":[{"given":"Constantin","family":"Hecker","sequence":"first","affiliation":[{"name":"Institute of Neurointervention, Paracelsus Medical University, Salzburg; and"},{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erasmia","family":"Broussalis","sequence":"additional","affiliation":[{"name":"Institute of Neurointervention, Paracelsus Medical University, Salzburg; and"},{"name":"Neurology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes A. 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J Neurointerv Surg. 2017;9(12):1191\u20131196.28096478"},{"issue":"5","key":"b2","series-title":"J Neurointerv Surg","first-page":"443","article-title":"Woven EndoBridge (WEB) device in the treatment of ruptured aneurysms","volume":"13","author":"Youssef PP","year":"2021","unstructured":"Youssef PP, Dornbos D III, Peterson J,  Woven EndoBridge (WEB) device in the treatment of ruptured aneurysms. J Neurointerv Surg. 2021;13(5):443\u2013446.32719167"},{"issue":"4","key":"b3","series-title":"J Neurointerv Surg","first-page":"363","article-title":"Aneurysm treatment with WEB in the cumulative population of two prospective, multicenter series: 3-year follow-up","volume":"13","author":"Pierot L","year":"2021","unstructured":"Pierot L, Szikora I, Barreau X,  Aneurysm treatment with WEB in the cumulative population of two prospective, multicenter series: 3-year follow-up. 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Stroke. 2001;32(9):1998\u20132004.11546888"},{"issue":"9","key":"b6","series-title":"J Neurointerv Surg","first-page":"927","article-title":"Validation of the Modified Raymond\u2013Roy classification for intracranial aneurysms treated with coil embolization","volume":"8","author":"Stapleton CJ","year":"2016","unstructured":"Stapleton CJ, Torok CM, Rabinov JD,  Validation of the Modified Raymond\u2013Roy classification for intracranial aneurysms treated with coil embolization. J Neurointerv Surg. 2016;8(9):927\u2013933.26438554"},{"issue":"7","key":"b7","series-title":"J Neurointerv Surg","first-page":"484","article-title":"Angiographic outcome of intracranial aneurysms with neck remnant following coil embolization","volume":"7","author":"Mascitelli JR","year":"2015","unstructured":"Mascitelli JR, Oermann EK, De Leacy RA, Moyle H, Patel AB. Angiographic outcome of intracranial aneurysms with neck remnant following coil embolization. J Neurointerv Surg. 2015;7(7):484\u2013489.24792578"},{"key":"b8","series-title":"R Foundation for Statistical Computing;","article-title":"R: a language and environment for statistical computing","author":"R Core Team","year":"2018","unstructured":"R Core Team. R: a language and environment for statistical computing. R Foundation for Statistical Computing; 2018.Accessed December 12, 2022.https:\/\/www.R-project.org"},{"issue":"12","key":"b9","series-title":"J Neurointerv Surg","first-page":"1197","article-title":"How safe and effective are existing treatments for wide-necked bifurcation aneurysms? Literature-based objective performance criteria for safety and effectiveness","volume":"9","author":"Fiorella D","year":"2017","unstructured":"Fiorella D, Arthur AS, Chiacchierini R, Emery E, Molyneux A, Pierot L. How safe and effective are existing treatments for wide-necked bifurcation aneurysms? Literature-based objective performance criteria for safety and effectiveness. 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