{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T10:57:22Z","timestamp":1780829842567,"version":"3.54.1"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>It has not been well-elucidated whether there are advantages to preserving bone flaps in abdominal subcutaneous (SQ) tissue after decompressive hemicraniectomy (DHC), compared to discarding bone flaps. The authors aimed to compare perioperative outcomes and costs for patients undergoing autologous cranioplasty (AC) after DHC with the bone flap preserved in abdominal SQ tissue, and for patients undergoing synthetic cranioplasty (SC).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>A retrospective review was performed of all patients undergoing DHC procedures between January 2017 and July 2021 at two tertiary care institutions. Patients were divided into two groups: those with flaps preserved in SQ tissue (SQ group), and those with the flap discarded (discarded group). Additional analysis was performed between patients undergoing AC versus SC. Primary end points included postoperative and surgical site complications. Secondary endpoints included operative costs, length of stay, and blood loss.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>A total of 248 patients who underwent DHC were included in the study, with 155 patients (62.5%) in the SQ group and 93 (37.5%) in the discarded group. Patients in the discarded group were more likely to have a diagnosis of severe TBI (57.0%), while the most prevalent diagnosis in the SQ group was malignant stroke (35.5%, p &lt; 0.05). There were 8 (5.2%) abdominal surgical site infections and 9 (5.8%) abdominal hematomas. The AC group had a significantly higher reoperation rate (23.2% vs 12.9%, p = 0.046), with 11% attributable to abdominal reoperations. The average cost of a reoperation for an abdominal complication was $40,408.75 \u00b1 $2273. When comparing the AC group to the SC group after cranioplasty, there were no significant differences in complications or surgical site infections. There were 6 cases of significant bone resorption requiring cement supplementation or discarding of the bone flap. Increased mean operative charges were found for the SC group compared to the AC group ($72,362 vs $59,726, p &lt; 0.001).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>Autologous bone flaps may offer a cost-effective option compared to synthetic flaps. However, when preserved in abdominal SQ tissue, they pose the risk of resorption over time as well as abdominal surgical site complications with increased reoperation rates. Further studies and methodologies such as cryopreservation of the bone flap may be beneficial to reduce costs and eliminate complications associated with abdominal SQ storage.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2022.3.jns212637","type":"journal-article","created":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T08:18:44Z","timestamp":1651825124000},"page":"1831-1838","source":"Crossref","is-referenced-by-count":18,"title":["Decompressive hemicraniectomy and cranioplasty using subcutaneously preserved autologous bone flaps versus synthetic implants: perioperative outcomes and cost analysis"],"prefix":"10.3171","volume":"137","author":[{"given":"Ehsan","family":"Dowlati","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, MedStar Georgetown University Hospital, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kory B. Dylan","family":"Pasko","sequence":"additional","affiliation":[{"name":"Georgetown University School of Medicine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esteban A.","family":"Molina","sequence":"additional","affiliation":[{"name":"Georgetown University School of Medicine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel R.","family":"Felbaum","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, MedStar Georgetown University Hospital, and"},{"name":"Department of Neurosurgery, MedStar Washington Hospital Center, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Bryan","family":"Mason","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, MedStar Washington Hospital Center, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey C.","family":"Mai","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, MedStar Georgetown University Hospital, and"},{"name":"Department of Neurosurgery, MedStar Washington Hospital Center, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Nathan","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, MedStar Georgetown University Hospital, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward F.","family":"Aulisi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, MedStar Washington Hospital Center, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocco A.","family":"Armonda","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, MedStar Georgetown University Hospital, and"},{"name":"Department of Neurosurgery, MedStar Washington Hospital Center, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"6","key":"b1","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E7","DOI":"10.3171\/2009.4.FOCUS0965","article-title":"Complications of decompressive craniectomy for traumatic brain injury","volume":"26","author":"Stiver SI","year":"2009","unstructured":"Stiver SI. Complications of decompressive craniectomy for traumatic brain injury. Neurosurg Focus. 2009;26(6):E7.1948572010.3171\/2009.4.FOCUS0965"},{"key":"b2","series-title":"Front Neurol","doi-asserted-by":"publisher","first-page":"977","DOI":"10.3389\/fneur.2018.00977","article-title":"Complications of decompressive craniectomy","volume":"9","author":"Gopalakrishnan MS","year":"2018","unstructured":"Gopalakrishnan MS, Shanbhag NC, Shukla DP, Konar SK, Bhat DI, Devi BI. Complications of decompressive craniectomy. Front Neurol. 2018;9:977.3052435910.3389\/fneur.2018.00977"},{"issue":"12","key":"b3","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1056\/NEJMoa1605215","article-title":"Trial of decompressive craniectomy for traumatic intracranial hypertension","volume":"375","author":"Hutchinson PJ","year":"2016","unstructured":"Hutchinson PJ, Kolias AG, Timofeev IS,  Trial of decompressive craniectomy for traumatic intracranial hypertension. N Engl J Med. 2016;375(12):1119\u20131130.2760250710.1056\/NEJMoa1605215"},{"issue":"2","key":"b4","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1093\/neuros\/nyx054","article-title":"Effects of cranioplasty on cerebral blood flow following decompressive craniectomy: a systematic review of the literature","volume":"81","author":"Halani SH","year":"2017","unstructured":"Halani SH, Chu JK, Malcolm JG,  Effects of cranioplasty on cerebral blood flow following decompressive craniectomy: a systematic review of the literature. Neurosurgery. 2017;81(2):204\u2013216.2836850510.1093\/neuros\/nyx054"},{"issue":"4","key":"b5","series-title":"Clin Imaging","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.clinimag.2010.07.008","article-title":"Multimodal imaging of recovery of functional networks associated with reversal of paradoxical herniation after cranioplasty","volume":"35","author":"Voss HU","year":"2011","unstructured":"Voss HU, Heier LA, Schiff ND. Multimodal imaging of recovery of functional networks associated with reversal of paradoxical herniation after cranioplasty. Clin Imaging. 2011;35(4):253\u2013258.2172411610.1016\/j.clinimag.2010.07.008"},{"issue":"1","key":"b6","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3171\/2016.10.JNS16678","article-title":"The effect of cranioplasty following decompressive craniectomy on cerebral blood perfusion, neurological, and cognitive outcome","volume":"128","author":"Shahid AH","year":"2018","unstructured":"Shahid AH, Mohanty M, Singla N, Mittal BR, Gupta SK. The effect of cranioplasty following decompressive craniectomy on cerebral blood perfusion, neurological, and cognitive outcome. J Neurosurg. 2018;128(1):229\u2013235.2829804210.3171\/2016.10.JNS16678"},{"key":"b7","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.jocn.2017.04.005","article-title":"Clinical and radiological assessment of cerebral hemodynamics after cranioplasty for decompressive craniectomy\u2014a clinical study","volume":"42","author":"Parichay PJ","year":"2017","unstructured":"Parichay PJ, Khanapure K, Joshi KC, Aniruddha TJ, Sandhya M, Hegde AS. Clinical and radiological assessment of cerebral hemodynamics after cranioplasty for decompressive craniectomy\u2014a clinical study. J Clin Neurosci. 2017;42:97\u2013101.10.1016\/j.jocn.2017.04.005"},{"issue":"3","key":"b8","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1093\/neuros\/nyx182","article-title":"Early cranioplasty is associated with greater neurological improvement: a systematic review and meta-analysis","volume":"82","author":"Malcolm JG","year":"2018","unstructured":"Malcolm JG, Rindler RS, Chu JK,  Early cranioplasty is associated with greater neurological improvement: a systematic review and meta-analysis. Neurosurgery. 2018;82(3):278\u2013288.2841935810.1093\/neuros\/nyx182"},{"issue":"4","key":"b9","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1227\/NEU.0000000000001366","article-title":"Syndrome of the trephined: a systematic review","volume":"79","author":"Ashayeri K","year":"2016","unstructured":"Ashayeri K, Jackson EM, Huang J, Brem H, Gordon CR. Syndrome of the trephined: a systematic review. Neurosurgery. 2016;79(4):525\u2013534.2748916610.1227\/NEU.0000000000001366"},{"issue":"5","key":"b10","series-title":"Br J Neurosurg","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1080\/02688697.2016.1187259","article-title":"Cranioplasty: morbidity and failure","volume":"30","author":"Honeybul S","year":"2016","unstructured":"Honeybul S, Ho KM. Cranioplasty: morbidity and failure. Br J Neurosurg. 2016;30(5):523\u2013528.2721593910.1080\/02688697.2016.1187259"},{"key":"b11","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.wneu.2017.12.061","article-title":"Massive brain swelling and death after cranioplasty: a systematic review","volume":"111","author":"Robles LA","year":"2018","unstructured":"Robles LA, Cuevas-Sol\u00f3rzano A. Massive brain swelling and death after cranioplasty: a systematic review. World Neurosurg. 2018;111:99\u2013108.2926906910.1016\/j.wneu.2017.12.061"},{"key":"b12","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.jocn.2016.04.017","article-title":"Complications following cranioplasty and relationship to timing: a systematic review and meta-analysis","volume":"33","author":"Malcolm JG","year":"2016","unstructured":"Malcolm JG, Rindler RS, Chu JK, Grossberg JA, Pradilla G, Ahmad FU. Complications following cranioplasty and relationship to timing: a systematic review and meta-analysis. J Clin Neurosci. 2016;33:39\u201351.2749912210.1016\/j.jocn.2016.04.017"},{"issue":"8","key":"b13","series-title":"Clin Neurol Neurosurg","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1016\/j.clineuro.2012.12.002","article-title":"Cranioplasty after decompressive hemicraniectomy: underestimated surgery-associated complications?","volume":"115","author":"Wachter D","year":"2013","unstructured":"Wachter D, Reineke K, Behm T, Rohde V. Cranioplasty after decompressive hemicraniectomy: underestimated surgery-associated complications?. Clin Neurol Neurosurg. 2013;115(8):1293\u20131297.2327338410.1016\/j.clineuro.2012.12.002"},{"key":"b14","first-page":"21","article-title":"Flow-diversion panacea or poison? Front Neurol","volume":"5","author":"Zanaty M","year":"2014","unstructured":"Zanaty M, Chalouhi N, Tjoumakaris SI, Rosenwasser RH, Gonzalez LF, Jabbour P. Flow-diversion panacea or poison? Front Neurol. 2014;5:21."},{"key":"b15","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.wneu.2017.03.022","article-title":"Cranioplasty complications and costs: a national population-level analysis using the MarketScan longitudinal database","volume":"102","author":"Li A","year":"2017","unstructured":"Li A, Azad TD, Veeravagu A,  Cranioplasty complications and costs: a national population-level analysis using the MarketScan longitudinal database. World Neurosurg. 2017;102:209\u2013220.2831580310.1016\/j.wneu.2017.03.022"},{"issue":"3","key":"b16","series-title":"Neurosurg Rev","doi-asserted-by":"publisher","first-page":"1755","DOI":"10.1007\/s10143-020-01374-4","article-title":"Long-term complications and implant survival rates after cranioplastic surgery: a single-center study of 392 patients","volume":"44","author":"Giese H","year":"2021","unstructured":"Giese H, Meyer J, Unterberg A, Beynon C. Long-term complications and implant survival rates after cranioplastic surgery: a single-center study of 392 patients. Neurosurg Rev. 2021;44(3):1755\u20131763.3284424910.1007\/s10143-020-01374-4"},{"issue":"4","key":"b17","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E19","DOI":"10.3171\/2014.2.FOCUS13561","article-title":"Materials used in cranioplasty: a history and analysis","volume":"36","author":"Shah AM","year":"2014","unstructured":"Shah AM, Jung H, Skirboll S. Materials used in cranioplasty: a history and analysis. Neurosurg Focus. 2014;36(4):E19.2468433110.3171\/2014.2.FOCUS13561"},{"issue":"3","key":"b18","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1093\/neuros\/nyab180","article-title":"Complications of cranioplasty in relation to material: systematic review, network meta-analysis and meta-regression","volume":"89","author":"Henry J","year":"2021","unstructured":"Henry J, Amoo M, Taylor J, O\u2019Brien DP. Complications of cranioplasty in relation to material: systematic review, network meta-analysis and meta-regression. Neurosurgery. 2021;89(3):383\u2013394.3410053510.1093\/neuros\/nyab180"},{"key":"b19","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1016\/j.wneu.2016.09.025","article-title":"Complications after in vivo and ex vivo autologous bone flap storage for cranioplasty: a comparative analysis of the literature","volume":"96","author":"Corliss B","year":"2016","unstructured":"Corliss B, Gooldy T, Vaziri S, Kubilis P, Murad G, Fargen K. Complications after in vivo and ex vivo autologous bone flap storage for cranioplasty: a comparative analysis of the literature. World Neurosurg. 2016;96:510\u2013515.2764703810.1016\/j.wneu.2016.09.025"},{"key":"b20","series-title":"Clin Neurol Neurosurg","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.clineuro.2014.06.029","article-title":"Cryopreservation versus subcutaneous preservation of autologous bone flaps for cranioplasty: comparison of the surgical site infection and bone resorption rates","volume":"124","author":"Cheng CH","year":"2014","unstructured":"Cheng CH, Lee HC, Chen CC, Cho DY, Lin HL. Cryopreservation versus subcutaneous preservation of autologous bone flaps for cranioplasty: comparison of the surgical site infection and bone resorption rates. Clin Neurol Neurosurg. 2014;124:85\u201389.2501945710.1016\/j.clineuro.2014.06.029"},{"issue":"6","key":"b21","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.3171\/2017.6.JNS17943","article-title":"Subcutaneous bone flap storage after emergency craniectomy: cost-effectiveness and rate of resorption","volume":"129","author":"Ernst G","year":"2018","unstructured":"Ernst G, Qeadan F, Carlson AP. Subcutaneous bone flap storage after emergency craniectomy: cost-effectiveness and rate of resorption. J Neurosurg. 2018;129(6):1604\u20131610.2930345010.3171\/2017.6.JNS17943"},{"issue":"5","key":"b22","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/j.wneu.2010.02.018","article-title":"Effectiveness and safety of subcutaneous abdominal preservation of autologous bone flap after decompressive craniectomy: a prospective pilot study","volume":"73","author":"Baldo S","year":"2010","unstructured":"Baldo S, Tacconi L. Effectiveness and safety of subcutaneous abdominal preservation of autologous bone flap after decompressive craniectomy: a prospective pilot study. World Neurosurg. 2010;73(5):552\u2013556.2092094110.1016\/j.wneu.2010.02.018"},{"key":"b23","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.wneu.2018.05.009","article-title":"Autologous cranioplasty is associated with increased reoperation rate: a systematic review and meta-analysis","volume":"116","author":"Malcolm JG","year":"2018","unstructured":"Malcolm JG, Mahmooth Z, Rindler RS,  Autologous cranioplasty is associated with increased reoperation rate: a systematic review and meta-analysis. World Neurosurg. 2018;116:60\u201368.10.1016\/j.wneu.2018.05.009"},{"key":"b24","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/j.wneu.2018.05.193","article-title":"Autologous bone is inferior to alloplastic cranioplasties: safety of autograft and allograft materials for cranioplasties, a systematic review","volume":"117","author":"van de Vijfeijken SECM","year":"2018","unstructured":"van de Vijfeijken SECM, M\u00fcnker TJAG, Spijker R,  Autologous bone is inferior to alloplastic cranioplasties: safety of autograft and allograft materials for cranioplasties, a systematic review. World Neurosurg. 2018;117:443\u2013452.e8.10.1016\/j.wneu.2018.05.193"},{"issue":"4","key":"b25","series-title":"Br J Neurosurg","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1080\/02688697.2020.1742291","article-title":"Comparison of complications in cranioplasty with various materials: a systematic review and meta-analysis","volume":"34","author":"Liu L","year":"2020","unstructured":"Liu L, Lu ST, Liu AH,  Comparison of complications in cranioplasty with various materials: a systematic review and meta-analysis. Br J Neurosurg. 2020;34(4):388\u2013396.3223381010.1080\/02688697.2020.1742291"},{"issue":"2","key":"b26","series-title":"Korean J Neurotrauma","doi-asserted-by":"publisher","first-page":"91","DOI":"10.13004\/kjnt.2021.17.e25","article-title":"Efficacy of 3D-printed titanium mesh-type patient-specific implant for cranioplasty","volume":"17","author":"Yoon HG","year":"2021","unstructured":"Yoon HG, Ko Y, Kim YS,  Efficacy of 3D-printed titanium mesh-type patient-specific implant for cranioplasty. Korean J Neurotrauma. 2021;17(2):91\u201399.3476081910.13004\/kjnt.2021.17.e25"},{"key":"b27","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.wneu.2021.02.104","article-title":"Cranioplasty using customized 3-dimensional-printed titanium implants: an international collaboration effort to improve neurosurgical care","volume":"149","author":"Nguyen B","year":"2021","unstructured":"Nguyen B, Ashraf O, Richards R, Tra H, Huynh T. Cranioplasty using customized 3-dimensional-printed titanium implants: an international collaboration effort to improve neurosurgical care. World Neurosurg. 2021;149:174\u2013180.3364749410.1016\/j.wneu.2021.02.104"},{"issue":"5","key":"b28","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1721","DOI":"10.3171\/2017.12.JNS172574","article-title":"Cranioplasty with a low-cost customized polymethylmethacrylate implant using a desktop 3D printer","volume":"130","author":"Morales-G\u00f3mez JA","year":"2019","unstructured":"Morales-G\u00f3mez JA, Garcia-Estrada E, Leos-Bortoni JE,  Cranioplasty with a low-cost customized polymethylmethacrylate implant using a desktop 3D printer. J Neurosurg. 2019;130(5):1721\u20131727.10.3171\/2017.12.JNS172574"},{"key":"b29","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.jocn.2021.06.042","article-title":"Comparison of subcutaneous pocket with cryopreservation method for storing autologous bone flaps in developing surgical wound infection after cranioplasty: a randomized clinical trial","volume":"91","author":"Shafiei M","year":"2021","unstructured":"Shafiei M, Sourani A, Saboori M, Aminmansour B, Mahram S. Comparison of subcutaneous pocket with cryopreservation method for storing autologous bone flaps in developing surgical wound infection after cranioplasty: a randomized clinical trial. J Clin Neurosci. 2021;91:136\u2013143.3437301910.1016\/j.jocn.2021.06.042"},{"key":"b30","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"e627","DOI":"10.1016\/j.wneu.2019.09.120","article-title":"Predictors of surgical site infection in autologous cranioplasty: a retrospective analysis of subcutaneously preserved bone flaps in abdominal pockets","volume":"133","author":"Alkhaibary A","year":"2020","unstructured":"Alkhaibary A, Alharbi A, Abbas M,  Predictors of surgical site infection in autologous cranioplasty: a retrospective analysis of subcutaneously preserved bone flaps in abdominal pockets. World Neurosurg. 2020;133:e627\u2013e632.3156891610.1016\/j.wneu.2019.09.120"},{"issue":"3","key":"b31","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1227\/01.NEU.0000350870.69891.86","article-title":"Long-term outcome of subcutaneously preserved autologous cranioplasty","volume":"65","author":"Shoakazemi A","year":"2009","unstructured":"Shoakazemi A, Flannery T, McConnell RS. Long-term outcome of subcutaneously preserved autologous cranioplasty. Neurosurgery. 2009;65(3):505\u2013510.1968769610.1227\/01.NEU.0000350870.69891.86"},{"issue":"3","key":"b32","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"710","DOI":"10.3171\/2015.4.JNS159","article-title":"Cranioplasty after decompressive craniectomy: is there a rationale for an initial artificial bone-substitute implant? A single-center experience after 631 procedures","volume":"124","author":"Schwarz F","year":"2016","unstructured":"Schwarz F, D\u00fcnisch P, Walter J, Sakr Y, Kalff R, Ewald C. Cranioplasty after decompressive craniectomy: is there a rationale for an initial artificial bone-substitute implant? A single-center experience after 631 procedures. J Neurosurg. 2016;124(3):710\u2013715.10.3171\/2015.4.JNS159"},{"issue":"3","key":"b33","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1007\/s00701-015-2679-y","article-title":"Long-term follow-up of cryopreservation with glycerol of autologous bone flaps for cranioplasty after decompressive craniectomy","volume":"158","author":"Takeuchi H","year":"2016","unstructured":"Takeuchi H, Higashino Y, Hosoda T,  Long-term follow-up of cryopreservation with glycerol of autologous bone flaps for cranioplasty after decompressive craniectomy. Acta Neurochir (Wien). 2016;158(3):571\u2013575.2673312910.1007\/s00701-015-2679-y"},{"issue":"1","key":"b34","series-title":"Plast Surg (Oakv)","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1177\/2292550319880922","article-title":"Comparative cost-effectiveness of cranioplasty implants","volume":"28","author":"Binhammer A","year":"2020","unstructured":"Binhammer A, Jakubowski J, Antonyshyn O, Binhammer P. Comparative cost-effectiveness of cranioplasty implants. Plast Surg (Oakv). 2020;28(1):29\u201339.3211064310.1177\/2292550319880922"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/137\/6\/article-p1831.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/137\/6\/article-p1831.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/137\/6\/article-p1831.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T11:04:36Z","timestamp":1716030276000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/137\/6\/article-p1831.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":34,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/2022.3.jns212637","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,1]]}}}