{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T13:57:46Z","timestamp":1793800666565,"version":"4.6.1"},"reference-count":52,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>The goal of microsurgical resection of vestibular schwannoma (VS) is gross-total resection (GTR) to provide oncological cure. However, a popular strategy is to halt the resection if the surgical team feels the risk of cranial nerve injury is imminent, achieving a maximally safe subtotal resection (STR) instead. The tumor remnant can then be treated with stereotactic radiosurgery (SRS) once the patient has recovered from the immediate postoperative period, or it can be followed with serial imaging and treated with SRS in a delayed fashion if residual tumor growth is seen. In this study, the authors evaluated the efficacy of this multimodality approach, particularly the influence of timing and dose of SRS on radiological tumor control, need for salvage treatment, and cranial nerve function.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>VS patients treated with initial microsurgery and subsequent radiosurgery were retrospectively included from two tertiary treatment centers and dichotomized depending on whether SRS was given upfront (defined as before 12 months) or later. Radiological tumor control was defined as less than 20% tumor volume expansion and oncological tumor control as an absence of salvage treatment. Facial and cochlear nerve functions were assessed after surgery, at the time of SRS, and at last follow-up. Finally, a systematic literature review was conducted according to PRISMA guidelines.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>A total of 110 VS patients underwent SRS following microsurgical resection, with a mean preradiosurgical tumor volume of 2.2 cm<jats:sup>3<\/jats:sup> (SD 2.5 cm<jats:sup>3<\/jats:sup>) and mean post-SRS follow-up time of 5.8 years (SD 4.1 years). The overall radiological tumor control and oncological tumor control were 77.3% and 90.9%, respectively. Thirty-five patients (31.8%) received upfront SRS, while 75 patients (68.2%) were observed for a minimum of 12 months prior to SRS. The timing of SRS did not influence the radiological tumor control (p = 0.869), the oncological tumor control (p = 0.560), or facial nerve (p = 0.413) or cochlear nerve (p = 0.954) function. An escalated marginal dose (&gt; 12 Gy) was associated with greater tumor shrinkage (p = 0.020) and superior radiological tumor control (p = 0.020), but it did not influence the risk of salvage treatment (p = 0.904) or facial (p = 0.351) or cochlear (p = 0.601) nerve deterioration.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>Delayed SRS after close observation of residuals following STR is a safe alternative to upfront SRS regarding tumor control and cranial nerve preservation in selected patients.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2022.5.jns22249","type":"journal-article","created":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T13:07:25Z","timestamp":1659704845000},"page":"420-429","source":"Crossref","is-referenced-by-count":18,"title":["Salvage radiosurgery following subtotal resection of vestibular schwannomas: does timing influence tumor control?"],"prefix":"10.3171","volume":"138","author":[{"given":"Dhanushan","family":"Dhayalan","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway;"},{"name":"Department of Clinical Medicine, University of Bergen, Norway; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avital","family":"Perry","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher S.","family":"Graffeo","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d8ystein Vesterli","family":"Tveiten","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Mu\u00f1oz Casabella","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce E.","family":"Pollock","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin L. W.","family":"Driscoll","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota;"},{"name":"Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew L.","family":"Carlson","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota;"},{"name":"Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Link","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota;"},{"name":"Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Lund-Johansen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway;"},{"name":"Department of Clinical Medicine, University of Bergen, Norway; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"14","key":"b1","series-title":"N Engl J Med","first-page":"1335","article-title":"Vestibular schwannomas","volume":"384","author":"Carlson ML","year":"2021","unstructured":"Carlson ML, Link MJ. Vestibular schwannomas. N Engl J Med. 2021;384(14):1335\u20131348.33826821"},{"issue":"4","key":"b2","series-title":"Neurol Med Chir (Tokyo)","first-page":"176","article-title":"Optimal extent of resection in vestibular schwannoma surgery: relationship to recurrence and facial nerve preservation","volume":"46","author":"Seol HJ","year":"2006","unstructured":"Seol HJ, Kim CH, Park CK,  Optimal extent of resection in vestibular schwannoma surgery: relationship to recurrence and facial nerve preservation. Neurol Med Chir (Tokyo). 2006;46(4):176\u2013181.16636507"},{"issue":"5","key":"b3","series-title":"Neurosurgery","first-page":"785","article-title":"Translabyrinthine removal of large acoustic neuromas","volume":"34","author":"Briggs RJ","year":"1994","unstructured":"Briggs RJ, Luxford WM, Atkins JS Jr, Hitselberger WE. Translabyrinthine removal of large acoustic neuromas. Neurosurgery. 1994;34(5):785\u2013791.8052375"},{"issue":"4","key":"b4","series-title":"J Neurosurg","first-page":"617","article-title":"Report of 190 consecutive cases of large acoustic tumors (vestibular schwannoma) removed via the translabyrinthine approach","volume":"90","author":"Lanman TH","year":"1999","unstructured":"Lanman TH, Brackmann DE, Hitselberger WE, Subin B. Report of 190 consecutive cases of large acoustic tumors (vestibular schwannoma) removed via the translabyrinthine approach. J Neurosurg. 1999;90(4):617\u2013623.10193604"},{"issue":"2","key":"b5","series-title":"Otol Neurotol","first-page":"224","article-title":"Translabyrinthine approach for the management of large and giant vestibular schwannomas","volume":"23","author":"Mamikoglu B","year":"2002","unstructured":"Mamikoglu B, Wiet RJ, Esquivel CR. Translabyrinthine approach for the management of large and giant vestibular schwannomas. 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N Engl J Med. 2021;385(4):381\u2013382.34289290"},{"issue":"2","key":"b46","series-title":"Laryngoscope","first-page":"378","article-title":"Magnetic resonance imaging surveillance following vestibular schwannoma resection","volume":"122","author":"Carlson ML","year":"2012","unstructured":"Carlson ML, van Abel KM, Driscoll CL,  Magnetic resonance imaging surveillance following vestibular schwannoma resection. Laryngoscope. 2012;122(2):378\u2013388.22252688"},{"issue":"4","key":"b47","series-title":"Neurosurgery","first-page":"654","article-title":"Vestibular schwannoma: surgery or gamma knife radiosurgery? A prospective, nonrandomized study","volume":"64","author":"Myrseth E","year":"2009","unstructured":"Myrseth E, M\u00f8ller P, Pedersen PH, Lund-Johansen M. Vestibular schwannoma: surgery or gamma knife radiosurgery? A prospective, nonrandomized study. Neurosurgery. 2009;64(4):654\u2013663."},{"issue":"8","key":"b48","series-title":"Laryngoscope","first-page":"1877","article-title":"Volumetric analysis of tumor control following subtotal and near-total resection of vestibular schwannoma","volume":"126","author":"Jacob JT","year":"2016","unstructured":"Jacob JT, Carlson ML, Driscoll CL, Link MJ. Volumetric analysis of tumor control following subtotal and near-total resection of vestibular schwannoma. Laryngoscope. 2016;126(8):1877\u20131882.27426941"},{"issue":"4","key":"b49","series-title":"J Neurosurg","first-page":"1052","article-title":"Long-term risk of recurrence and regrowth after gross-total and subtotal resection of sporadic vestibular schwannoma","volume":"133","author":"Nakatomi H","year":"2020","unstructured":"Nakatomi H, Jacob JT, Carlson ML,  Long-term risk of recurrence and regrowth after gross-total and subtotal resection of sporadic vestibular schwannoma. J Neurosurg. 2020;133(4):1052\u20131058."},{"issue":"7","key":"b50","series-title":"Laryngoscope","first-page":"1703","article-title":"Near total extirpation of vestibular schwannoma with salvage radiosurgery","volume":"125","author":"Jeltema HR","year":"2015","unstructured":"Jeltema HR, Bakker NA, Bijl HP, Wagemakers M, Metzemaekers JD, van Dijk JM. Near total extirpation of vestibular schwannoma with salvage radiosurgery. Laryngoscope. 2015;125(7):1703\u20131707.25583352"},{"issue":"8","key":"b51","series-title":"Otol Neurotol","first-page":"1456","article-title":"Evaluation of the increased use of partial resection of large vestibular schwanommas: facial nerve outcomes and recurrence\/regrowth rates","volume":"34","author":"Schwartz MS","year":"2013","unstructured":"Schwartz MS, Kari E, Strickland BM,  Evaluation of the increased use of partial resection of large vestibular schwanommas: facial nerve outcomes and recurrence\/regrowth rates. 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