{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T02:05:12Z","timestamp":1783217112607,"version":"3.54.6"},"reference-count":35,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>Endoscopic strip craniectomy for metopic craniosynostosis relies on rapid growth and postoperative helmeting for correction. Endoscopic repair is generally performed before patients reach 4 months of age, and outcomes in older patients have yet to be quantified. Here, the authors examined a cohort of patients treated with endoscopic repair before or after 4 months of age to determine aesthetic outcomes of delayed repairs.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>Data from eligible patients were retrospectively assessed and aggregated in a dedicated metopic synostosis database. Inclusion criteria were radiographically confirmed metopic synostosis and endoscopic treatment. Patients were dichotomized into two groups: those younger than 4 months and those 4 months or older at the time of repair. The frontal width and interfrontal divergence angle (IFDA) were measured on reconstructed CT images. These measurements, alongside operative time, estimated blood loss, and transfusion rates, were compared between groups using the Student t-test or chi-square test.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>The study population comprised 28 patients treated before 4 months of age and 8 patients treated at 4\u20136 months of age. Patient sex and perioperative complications did not differ by age group. Older age at repair was not significantly associated with 1-year postoperative IFDA (140\u00b0 \u00b1 4.2\u00b0 vs 142\u00b0 \u00b1 5.0\u00b0, p = 0.28) or frontal width (84 \u00b1 5.2 vs 83 \u00b1 4.4 mm, p = 0.47).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>One-year postoperative IFDA and frontal width do not differ significantly between patients treated before and after 4 months of age. Further study with longer follow-up is necessary to confirm the longevity of these results at skeletal maturity.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2022.8.peds22214","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T12:08:56Z","timestamp":1664539736000},"page":"595-601","source":"Crossref","is-referenced-by-count":3,"title":["Impact of age at endoscopic metopic synostosis repair on anthropometric outcomes"],"prefix":"10.3171","volume":"30","author":[{"given":"Sarah N.","family":"Chiang","sequence":"first","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Department of Surgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin C.","family":"Peterson","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Department of Surgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Lauzier","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery; and"},{"name":"Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean D.","family":"McEvoy","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary B.","family":"Skolnick","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Department of Surgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sybill D.","family":"Naidoo","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Department of Surgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew D.","family":"Smyth","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamlesh B.","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Department of Surgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"1","key":"b1","series-title":"Plast Reconstr Surg","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/PRS.0000000000001938","article-title":"What\u2019s in a name? 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