{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T02:45:53Z","timestamp":1782787553184,"version":"3.54.5"},"reference-count":33,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>The purpose of this study was to determine the incidence, mechanism, and potential protective strategies for pelvic fixation failure (PFF) within 2 years after adult spinal deformity (ASD) surgery.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>Data for ASD patients (age \u2265 18 years, minimum of six instrumented levels) with pelvic fixation (S2-alar-iliac [S2AI] and\/or iliac screws) with a minimum 2-year follow-up were consecutively collected (2015\u20132019). Patients with prior pelvic fixation were excluded. PFF was defined as any revision to pelvic screws, which may include broken rods across the lumbosacral junction requiring revision to pelvic screws, pseudarthrosis across the lumbosacral junction requiring revision to pelvic screws, a broken or loose pelvic screw, or sacral\/iliac fracture. Patient information including demographic data and health history (age, sex, BMI, smoking status, American Society of Anesthesiologists score, osteoporosis), operative (total instrumented levels [TIL], three-column osteotomy [3CO], interbody fusion), screw (iliac, S2AI, length, diameter), rod (diameter, kickstand), rod pattern (number crossing lumbopelvic junction, lowest instrumented vertebra [LIV] of accessory rod[s], lateral connectors, dual-headed screws), and pre- and postradiographic (lumbar lordosis, pelvic incidence, pelvic tilt, major Cobb angle, lumbosacral fractional curve, C7 coronal vertical axis [CVA], T1 pelvic angle, C7 sagittal vertical axis) parameters was collected. All rods across the lumbosacral junction were cobalt-chrome. All iliac and S2AI screws were closed-headed tulips. Both univariate and multivariate analyses were performed to determine risk factors for PFF.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Of 253 patients (mean age 58.9 years, mean TIL 13.6, 3CO 15.8%, L5\u2013S1 interbody 74.7%, mean pelvic screw diameter\/length 8.6\/87 mm), the 2-year failure rate was 4.3% (n = 11). The mechanisms of failure included broken rods across the lumbosacral junction (n = 4), pseudarthrosis across the lumbosacral junction requiring revision to pelvic screws (n = 3), broken pelvic screw (n = 1), loose pelvic screw (n = 1), sacral\/iliac fracture (n = 1), and painful\/prominent pelvic screw (n = 1). A higher number of rods crossing the lumbopelvic junction (mean 3.8 no failure vs 2.9 failure, p = 0.009) and accessory rod LIV to S2\/ilium (no failure 54.2% vs failure 18.2%, p = 0.003) were protective for failure. Multivariate analysis demonstrated that accessory rod LIV to S2\/ilium versus S1 (OR 0.2, p = 0.004) and number of rods crossing the lumbar to pelvis (OR 0.15, p = 0.002) were protective, while worse postoperative CVA (OR 1.5, p = 0.028) was an independent risk factor for failure.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>The 2-year PFF rate was low relative to what is reported in the literature, despite patients undergoing long fusion constructs for ASD. The number of rods crossing the lumbopelvic junction and accessory rod LIV to S2\/ilium relative to S1 alone likely increase construct stiffness. Residual postoperative coronal malalignment should be avoided to reduce PFF.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2022.8.spine22755","type":"journal-article","created":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T08:49:54Z","timestamp":1665737394000},"page":"208-216","source":"Crossref","is-referenced-by-count":29,"title":["Incidence, mechanism, and protective strategies for 2-year pelvic fixation failure after adult spinal deformity surgery with a minimum six-level fusion"],"prefix":"10.3171","volume":"38","author":[{"given":"Nathan J.","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Marciano","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varun","family":"Puvanesarajah","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William E.","family":"Clifton","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Kwan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cole R.","family":"Morrissette","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaques L.","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Fields","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fthimnir M.","family":"Hassan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter D.","family":"Angevine","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher E.","family":"Mandigo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M.","family":"Lombardi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeeshan M.","family":"Sardar","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald A.","family":"Lehman","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence G.","family":"Lenke","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at NewYork-Presbyterian, New York, New 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Reduced occurrence of primary rod fracture after adult spinal deformity surgery with accessory supplemental rods: retrospective analysis of 114 patients with minimum 2-year follow-up. J Neurosurg Spine. 2021;35(4):504\u2013515.34298503"},{"issue":"2","key":"b32","series-title":"Neurospine","first-page":"466","article-title":"Dual S2 alar-iliac screw technique with a multirod construct across the lumbosacral junction: obtaining adequate stability at the lumbosacral junction in spinal deformity surgery","volume":"17","author":"Park PJ","year":"2020","unstructured":"Park PJ, Lin JD, Makhni MC, Cerpa M, Lehman RA, Lenke LG. Dual S2 alar-iliac screw technique with a multirod construct across the lumbosacral junction: obtaining adequate stability at the lumbosacral junction in spinal deformity surgery. 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