{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T09:03:12Z","timestamp":1780131792612,"version":"3.54.0"},"reference-count":62,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>In other specialties, malnutrition has been shown to be closely linked to postoperative complications. However, there is no research on the relationship between nutritional parameters and the complications of transsphenoidal pituitary surgery. This study was designed to identify the relationship between preoperative nutritional markers and postoperative complications in nonfunctioning pituitary adenomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>This observational study included 429 patients whose first transsphenoidal surgery was performed in Shandong Provincial Hospital between January 2015 and July 2020. Preoperative prealbumin, retinol-binding protein (RBP), the prognostic nutritional index, clinicopathological data, and postoperative complication data were collected to investigate outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>After multivariable adjustment, preoperative prealbumin and RBP were inversely associated with risk of complication (p value for trend = 0.006, 0.021). The increase of preoperative serum prealbumin and RBP concentration may decrease the risk of postoperative intracranial infection and hyponatremia (both OR per SD increment, &lt; 1; p &lt; 0.05). The increase of preoperative prealbumin may also decrease the risk of diabetes insipidus (OR per SD increment, 0.591; p = 0.001), but similar results were not obtained for the RBP (p &gt; 0.05). Prealbumin and RBP are both useful in predicting overall complications (area under the receiver operating characteristic curve [AUC] 0.749, 0.678), especially in intracranial infection (AUC 0.794, 0.738). However, the predictive value of prealbumin was better than that of RBP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Low preoperative prealbumin or RBP concentrations may be associated with higher surgical risk, especially for intracranial infection. This study emphasizes the suggestion that preoperative prealbumin and RBP concentrations may be vital factors in predicting operative complications of nonfunctioning pituitary adenomas.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2022.9.focus22211","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T13:03:09Z","timestamp":1669899789000},"page":"E6","source":"Crossref","is-referenced-by-count":11,"title":["Low preoperative serum prealbumin levels and risk of postoperative complications after transsphenoidal surgery in nonfunctioning pituitary adenoma"],"prefix":"10.3171","volume":"53","author":[{"given":"Shuaihua","family":"Song","sequence":"first","affiliation":[{"name":"Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoran","family":"Wang","sequence":"additional","affiliation":[{"name":"Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianjin","family":"Qi","sequence":"additional","affiliation":[{"name":"Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"4","key":"b1","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E19","DOI":"10.3171\/2020.7.FOCUS20524","article-title":"Clinical characteristics and outcomes in elderly patients undergoing transsphenoidal surgery for nonfunctioning pituitary adenoma","volume":"49","author":"Pereira MP","year":"2020","unstructured":"Pereira MP, Oh T, Joshi RS,  Clinical characteristics and outcomes in elderly patients undergoing transsphenoidal surgery for nonfunctioning pituitary adenoma. Neurosurg Focus. 2020;49(4):E19.10.3171\/2020.7.FOCUS2052411989633"},{"issue":"6","key":"b2","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E13","DOI":"10.3171\/2020.3.FOCUS20114","article-title":"Clinical characteristics and outcomes of null-cell versus silent gonadotroph adenomas in a series of 1166 pituitary adenomas from a single institution","volume":"48","author":"Haddad A","year":"2020","unstructured":"Haddad A, Young J, Oh T,  Clinical characteristics and outcomes of null-cell versus silent gonadotroph adenomas in a series of 1166 pituitary adenomas from a single institution. Neurosurg Focus. 2020;48(6):E13.10.3171\/2020.3.FOCUS2011430203747"},{"issue":"1","key":"b3","series-title":"Pituitary","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1007\/s11102-017-0839-1","article-title":"Preoperative risk factors for postoperative complications in endoscopic pituitary surgery: a systematic review","volume":"21","author":"Lobatto DJ","year":"2018","unstructured":"Lobatto DJ, de Vries F, Zamanipoor Najafabadi AH,  Preoperative risk factors for postoperative complications in endoscopic pituitary surgery: a systematic review. Pituitary. 2018;21(1):84\u201397.10.1007\/s11102-017-0839-132896169"},{"issue":"4","key":"b4","series-title":"Neurol India","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.4103\/0028-3886.266241","article-title":"Endoscopic versus microscopic pituitary adenoma surgery: a single-center study","volume":"67","author":"Pablo A","year":"2019","unstructured":"Pablo A, Sofia B, Maximiliano T,  Endoscopic versus microscopic pituitary adenoma surgery: a single-center study. Neurol India. 2019;67(4):1015\u20131021.10.4103\/0028-3886.2662419475481"},{"issue":"8","key":"b5","series-title":"Mayo Clin Proc","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1016\/j.mayocp.2021.06.017","article-title":"Surgery for pituitary adenoma: endoscope versus microscope: does it make a difference?","volume":"96","author":"Chicoine MR","year":"2021","unstructured":"Chicoine MR. Surgery for pituitary adenoma: endoscope versus microscope: does it make a difference? Mayo Clin Proc. 2021;96(8):2020\u20132021.10.1016\/j.mayocp.2021.06.01711989633"},{"issue":"1","key":"b6","series-title":"Sci Rep","doi-asserted-by":"publisher","first-page":"21942","DOI":"10.1038\/s41598-020-78823-z","article-title":"Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study","volume":"10","author":"M\u00f8ller MW","year":"2020","unstructured":"M\u00f8ller MW, Andersen MS, Glintborg D,  Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study. Sci Rep. 2020;10(1):21942.10.1038\/s41598-020-78823-z30203747"},{"issue":"5","key":"b7","series-title":"J Neurosurg Spine","doi-asserted-by":"publisher","first-page":"549","DOI":"10.3171\/2018.3.SPINE171183","article-title":"Low preoperative serum prealbumin levels and the postoperative surgical site infection risk in elective spine surgery: a consecutive series","volume":"29","author":"Salvetti DJ","year":"2018","unstructured":"Salvetti DJ, Tempel ZJ, Goldschmidt E,  Low preoperative serum prealbumin levels and the postoperative surgical site infection risk in elective spine surgery: a consecutive series. J Neurosurg Spine. 2018;29(5):549\u2013552.10.3171\/2018.3.SPINE17118332896169"},{"issue":"7","key":"b8","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1212\/WNL.0000000000001259","article-title":"Inflammation, negative nitrogen balance, and outcome after aneurysmal subarachnoid hemorrhage","volume":"84","author":"Badjatia N","year":"2015","unstructured":"Badjatia N, Monahan A, Carpenter A,  Inflammation, negative nitrogen balance, and outcome after aneurysmal subarachnoid hemorrhage. Neurology. 2015;84(7):680\u2013687.10.1212\/WNL.00000000000012599475481"},{"issue":"2","key":"b9","series-title":"Am J Surg","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.amjsurg.2010.06.021","article-title":"The C-reactive protein-to-prealbumin ratio predicts fistula closure","volume":"202","author":"Harriman S","year":"2011","unstructured":"Harriman S, Rodych N, Hayes P, Moser MAJ. The C-reactive protein-to-prealbumin ratio predicts fistula closure. Am J Surg. 2011;202(2):175\u2013178.10.1016\/j.amjsurg.2010.06.021"},{"issue":"4","key":"b10","series-title":"Surgery","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1067\/msy.1998.91365","article-title":"The C-reactive protein to prealbumin ratio correlates with the severity of multiple organ dysfunction","volume":"124","author":"Pinilla J","year":"1998","unstructured":"Pinilla J, Hayes P, Laverty W, Arnold C, Laxdal V. The C-reactive protein to prealbumin ratio correlates with the severity of multiple organ dysfunction. Surgery. 1998;124(4):799\u2013805.10.1067\/msy.1998.91365"},{"issue":"2","key":"b11","series-title":"Ann Surg Oncol","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1245\/s10434-016-5548-x","article-title":"Role of prealbumin as a powerful and simple index for predicting postoperative complications after gastric cancer surgery","volume":"24","author":"Zhou J","year":"2017","unstructured":"Zhou J, Hiki N, Mine S,  Role of prealbumin as a powerful and simple index for predicting postoperative complications after gastric cancer surgery. Ann Surg Oncol. 2017;24(2):510\u2013517.10.1245\/s10434-016-5548-x"},{"issue":"8","key":"b12","series-title":"Am Fam Physician","first-page":"1575","article-title":"Prealbumin: a marker for nutritional evaluation","volume":"65","author":"Beck FK","year":"2002","unstructured":"Beck FK, Rosenthal TC. Prealbumin: a marker for nutritional evaluation. Am Fam Physician. 2002;65(8):1575\u20131578."},{"issue":"12","key":"b13","series-title":"Clin Chem Lab Med","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1515\/CCLM.2002.232","article-title":"Transthyretin: its response to malnutrition and stress injury. clinical usefulness and economic implications","volume":"40","author":"Bernstein LH","year":"2002","unstructured":"Bernstein LH, Ingenbleek Y. Transthyretin: its response to malnutrition and stress injury. clinical usefulness and economic implications. Clin Chem Lab Med. 2002;40(12):1344\u20131348.10.1515\/CCLM.2002.232"},{"issue":"Suppl 3","key":"b14","series-title":"Intern Emerg Med","doi-asserted-by":"publisher","first-page":"S193","DOI":"10.1007\/s11739-012-0802-0","article-title":"Hypoalbuminemia","volume":"7","author":"Gatta A","year":"2012","unstructured":"Gatta A, Verardo A, Bolognesi MJ. Hypoalbuminemia. Intern Emerg Med. 2012;7Suppl 3:S193-S199.10.1007\/s11739-012-0802-0"},{"issue":"6","key":"b15","series-title":"J Clin Med","doi-asserted-by":"publisher","first-page":"775","DOI":"10.3390\/jcm8060775","article-title":"Nutritional laboratory markers in malnutrition","volume":"8","author":"Keller U","year":"2019","unstructured":"Keller U. Nutritional laboratory markers in malnutrition. J Clin Med. 2019;8(6):775.10.3390\/jcm8060775"},{"issue":"7","key":"b16","series-title":"JPEN J Parenter Enteral Nutr","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1177\/0148607114536735","article-title":"Impact of preoperative prealbumin on outcomes after cardiac surgery","volume":"39","author":"Yu P","year":"2015","unstructured":"Yu P, Cassiere H, Dellis S,  Impact of preoperative prealbumin on outcomes after cardiac surgery. JPEN J Parenter Enteral Nutr. 2015;39(7):870\u2013874.10.1177\/0148607114536735"},{"issue":"4 Special","key":"b17","series-title":"Pak J Pharm Sci","first-page":"1613","article-title":"Significance of retinol binding protein and prealbumin in neonatal nutritional evaluation","volume":"31","author":"Zhang Y","year":"2018","unstructured":"Zhang Y, Zhang M, Yang X,  Significance of retinol binding protein and prealbumin in neonatal nutritional evaluation. Pak J Pharm Sci. 2018;31(4 Special):1613\u20131616."},{"issue":"3","key":"b18","series-title":"Pituitary","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1007\/s11102-020-01112-5","article-title":"Pre-operative serum inflammation-based scores in patients with pituitary adenomas","volume":"24","author":"Marques P","year":"2021","unstructured":"Marques P, de Vries F, Dekkers OM,  Pre-operative serum inflammation-based scores in patients with pituitary adenomas. Pituitary. 2021;24(3):334\u2013350.10.1007\/s11102-020-01112-5"},{"issue":"3","key":"b19","series-title":"Endocrine","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1007\/s12020-020-02554-4","article-title":"Impact of age on postsurgical outcomes of nonfunctioning pituitary adenomas","volume":"72","author":"Biamonte E","year":"2021","unstructured":"Biamonte E, Betella N, Milani D,  Impact of age on postsurgical outcomes of nonfunctioning pituitary adenomas. Endocrine. 2021;72(3):915\u2013922.10.1007\/s12020-020-02554-4"},{"issue":"3","key":"b20","series-title":"Pituitary","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1007\/s11102-020-01108-1","article-title":"Cephalocaudal tumor diameter is a predictor of diabetes insipidus after endoscopic transsphenoidal surgery for non-functioning pituitary adenoma","volume":"24","author":"Oh H","year":"2021","unstructured":"Oh H, Cheun H, Kim YJ,  Cephalocaudal tumor diameter is a predictor of diabetes insipidus after endoscopic transsphenoidal surgery for non-functioning pituitary adenoma. Pituitary. 2021;24(3):303\u2013311.10.1007\/s11102-020-01108-1"},{"key":"b21","series-title":"Br J Neurosurg","article-title":"Subclinical hemorrhagic nonfunctionning pituitary adenoma: pituitary gland function status, endoscopic endonasal transsphenoidal surgery, and outcomes","author":"Wang M","unstructured":"Wang M, Jiang Y, Cai Y, Wu H, Peng Y. Subclinical hemorrhagic nonfunctionning pituitary adenoma: pituitary gland function status, endoscopic endonasal transsphenoidal surgery, and outcomes. Br J Neurosurg. Published online September 8, 2020. doi:10.1080\/02688697.2020.1815651"},{"issue":"4","key":"b22","series-title":"Curr Opin Pediatr","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1097\/MOP.0000000000000779","article-title":"Diagnosis and management of hypopituitarism","volume":"31","author":"Yeliosof O","year":"2019","unstructured":"Yeliosof O, Gangat M. Diagnosis and management of hypopituitarism. Curr Opin Pediatr. 2019;31(4):531\u2013536.10.1097\/MOP.0000000000000779"},{"issue":"10058","key":"b23","series-title":"Lancet","doi-asserted-by":"publisher","first-page":"2403","DOI":"10.1016\/S0140-6736(16)30053-8","article-title":"Hypopituitarism","volume":"388","author":"Higham CE","year":"2016","unstructured":"Higham CE, Johannsson G, Shalet SM. Hypopituitarism. Lancet. 2016;388(10058):2403\u20132415.10.1016\/S0140-6736(16)30053-8"},{"key":"b24","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"e851","DOI":"10.1016\/j.wneu.2017.11.125","article-title":"Risk factors and microbiology of meningitis and\/or bacteremia after transsphenoidal surgery for pituitary adenoma","volume":"110","author":"Jin Y","year":"2018","unstructured":"Jin Y, Liu X, Gao L,  Risk factors and microbiology of meningitis and\/or bacteremia after transsphenoidal surgery for pituitary adenoma. World Neurosurg. 2018;110:e851\u2013e863.10.1016\/j.wneu.2017.11.125"},{"issue":"2","key":"b25","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E5","DOI":"10.3171\/2019.5.FOCUS19269","article-title":"Risk factors for postoperative intracranial infections in patients with pituitary adenoma after endoscopic endonasal transsphenoidal surgery: pneumocephalus deserves further study","volume":"47","author":"Guo K","year":"2019","unstructured":"Guo K, Heng L, Zhang H, Ma L, Zhang H, Jia D. Risk factors for postoperative intracranial infections in patients with pituitary adenoma after endoscopic endonasal transsphenoidal surgery: pneumocephalus deserves further study. Neurosurg Focus. 2019;47(2):E5.10.3171\/2019.5.FOCUS19269"},{"issue":"1","key":"b26","series-title":"J Maxillofac Oral Surg","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1007\/s12663-018-1105-4","article-title":"Assessment of severity of illness and monitoring response to treatment of odontogenic space infection using serum prealbumin","volume":"18","author":"Adeosun PO","year":"2019","unstructured":"Adeosun PO, Fatusi OA, Adedeji TA. Assessment of severity of illness and monitoring response to treatment of odontogenic space infection using serum prealbumin. J Maxillofac Oral Surg. 2019;18(1):106\u2013111.10.1007\/s12663-018-1105-4"},{"issue":"2","key":"b27","series-title":"Int J Environ Res Public Health","doi-asserted-by":"publisher","first-page":"514","DOI":"10.3390\/ijerph8020514","article-title":"Hospital malnutrition: prevalence, identification and impact on patients and the healthcare system","volume":"8","author":"Barker LA","year":"2011","unstructured":"Barker LA, Gout BS, Crowe TC. Hospital malnutrition: prevalence, identification and impact on patients and the healthcare system. Int J Environ Res Public Health. 2011;8(2):514\u2013527.10.3390\/ijerph8020514"},{"issue":"4","key":"b28","series-title":"Neurosurg Clin N Am","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.nec.2019.05.011","article-title":"Sodium perturbations after pituitary surgery","volume":"30","author":"Yuen KCJ","year":"2019","unstructured":"Yuen KCJ, Ajmal A, Correa R, Little AS. Sodium perturbations after pituitary surgery. Neurosurg Clin N Am. 2019;30(4):515\u2013524.10.1016\/j.nec.2019.05.011"},{"issue":"4","key":"b29","series-title":"J Clin Med","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.3390\/jcm3041199","article-title":"Incidence, etiology and outcomes of hyponatremia after transsphenoidal surgery: experience with 344 consecutive patients at a single tertiary center","volume":"3","author":"Barber S","year":"2014","unstructured":"Barber S, Liebelt B, Baskin DJJ. Incidence, etiology and outcomes of hyponatremia after transsphenoidal surgery: experience with 344 consecutive patients at a single tertiary center. J Clin Med. 2014;3(4):1199\u20131219.10.3390\/jcm3041199"},{"key":"b30","series-title":"Kidney Int Suppl","first-page":"S12","article-title":"Severe hyponatremia after transsphenoidal surgery for pituitary adenomas","volume":"64","author":"Boehnert M","year":"1998","unstructured":"Boehnert M, Hensen J, Henig A, Fahlbusch R, Gross P, Buchfelder M. Severe hyponatremia after transsphenoidal surgery for pituitary adenomas. Kidney Int Suppl. 1998;64:S12\u2013S14."},{"issue":"5","key":"b31","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1093\/neuros\/nyaa148","article-title":"Diabetes insipidus after endoscopic transsphenoidal surgery","volume":"87","author":"Burke WT","year":"2020","unstructured":"Burke WT, Cote DJ, Penn DL, Iuliano S, McMillen K, Laws ER. Diabetes insipidus after endoscopic transsphenoidal surgery. Neurosurgery. 2020;87(5):949\u2013955.10.1093\/neuros\/nyaa148"},{"issue":"4","key":"b1","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E19","DOI":"10.3171\/2020.7.FOCUS20524","article-title":"Clinical characteristics and outcomes in elderly patients undergoing transsphenoidal surgery for nonfunctioning pituitary adenoma","volume":"49","author":"Pereira MP","year":"2020","unstructured":"Pereira MP, Oh T, Joshi RS,  Clinical characteristics and outcomes in elderly patients undergoing transsphenoidal surgery for nonfunctioning pituitary adenoma. Neurosurg Focus. 2020;49(4):E19.10.3171\/2020.7.FOCUS20524"},{"issue":"6","key":"b2","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E13","DOI":"10.3171\/2020.3.FOCUS20114","article-title":"Clinical characteristics and outcomes of null-cell versus silent gonadotroph adenomas in a series of 1166 pituitary adenomas from a single institution","volume":"48","author":"Haddad A","year":"2020","unstructured":"Haddad A, Young J, Oh T,  Clinical characteristics and outcomes of null-cell versus silent gonadotroph adenomas in a series of 1166 pituitary adenomas from a single institution. Neurosurg Focus. 2020;48(6):E13.10.3171\/2020.3.FOCUS20114"},{"issue":"1","key":"b3","series-title":"Pituitary","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1007\/s11102-017-0839-1","article-title":"Preoperative risk factors for postoperative complications in endoscopic pituitary surgery: a systematic review","volume":"21","author":"Lobatto DJ","year":"2018","unstructured":"Lobatto DJ, de Vries F, Zamanipoor Najafabadi AH,  Preoperative risk factors for postoperative complications in endoscopic pituitary surgery: a systematic review. Pituitary. 2018;21(1):84\u201397.10.1007\/s11102-017-0839-1"},{"issue":"4","key":"b4","series-title":"Neurol India","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.4103\/0028-3886.266241","article-title":"Endoscopic versus microscopic pituitary adenoma surgery: a single-center study","volume":"67","author":"Pablo A","year":"2019","unstructured":"Pablo A, Sofia B, Maximiliano T,  Endoscopic versus microscopic pituitary adenoma surgery: a single-center study. Neurol India. 2019;67(4):1015\u20131021.10.4103\/0028-3886.266241"},{"issue":"8","key":"b5","series-title":"Mayo Clin Proc","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1016\/j.mayocp.2021.06.017","article-title":"Surgery for pituitary adenoma: endoscope versus microscope: does it make a difference?","volume":"96","author":"Chicoine MR","year":"2021","unstructured":"Chicoine MR. Surgery for pituitary adenoma: endoscope versus microscope: does it make a difference? Mayo Clin Proc. 2021;96(8):2020\u20132021.10.1016\/j.mayocp.2021.06.017"},{"issue":"1","key":"b6","series-title":"Sci Rep","doi-asserted-by":"publisher","first-page":"21942","DOI":"10.1038\/s41598-020-78823-z","article-title":"Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study","volume":"10","author":"M\u00f8ller MW","year":"2020","unstructured":"M\u00f8ller MW, Andersen MS, Glintborg D,  Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study. Sci Rep. 2020;10(1):21942.10.1038\/s41598-020-78823-z"},{"issue":"5","key":"b7","series-title":"J Neurosurg Spine","doi-asserted-by":"publisher","first-page":"549","DOI":"10.3171\/2018.3.SPINE171183","article-title":"Low preoperative serum prealbumin levels and the postoperative surgical site infection risk in elective spine surgery: a consecutive series","volume":"29","author":"Salvetti DJ","year":"2018","unstructured":"Salvetti DJ, Tempel ZJ, Goldschmidt E,  Low preoperative serum prealbumin levels and the postoperative surgical site infection risk in elective spine surgery: a consecutive series. J Neurosurg Spine. 2018;29(5):549\u2013552.10.3171\/2018.3.SPINE171183"},{"issue":"7","key":"b8","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1212\/WNL.0000000000001259","article-title":"Inflammation, negative nitrogen balance, and outcome after aneurysmal subarachnoid hemorrhage","volume":"84","author":"Badjatia N","year":"2015","unstructured":"Badjatia N, Monahan A, Carpenter A,  Inflammation, negative nitrogen balance, and outcome after aneurysmal subarachnoid hemorrhage. Neurology. 2015;84(7):680\u2013687.10.1212\/WNL.0000000000001259"},{"issue":"2","key":"b9","series-title":"Am J Surg","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.amjsurg.2010.06.021","article-title":"The C-reactive protein-to-prealbumin ratio predicts fistula closure","volume":"202","author":"Harriman S","year":"2011","unstructured":"Harriman S, Rodych N, Hayes P, Moser MAJ. The C-reactive protein-to-prealbumin ratio predicts fistula closure. Am J Surg. 2011;202(2):175\u2013178.10.1016\/j.amjsurg.2010.06.021"},{"issue":"4","key":"b10","series-title":"Surgery","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1067\/msy.1998.91365","article-title":"The C-reactive protein to prealbumin ratio correlates with the severity of multiple organ dysfunction","volume":"124","author":"Pinilla J","year":"1998","unstructured":"Pinilla J, Hayes P, Laverty W, Arnold C, Laxdal V. The C-reactive protein to prealbumin ratio correlates with the severity of multiple organ dysfunction. Surgery. 1998;124(4):799\u2013805.10.1067\/msy.1998.91365"},{"issue":"2","key":"b11","series-title":"Ann Surg Oncol","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1245\/s10434-016-5548-x","article-title":"Role of prealbumin as a powerful and simple index for predicting postoperative complications after gastric cancer surgery","volume":"24","author":"Zhou J","year":"2017","unstructured":"Zhou J, Hiki N, Mine S,  Role of prealbumin as a powerful and simple index for predicting postoperative complications after gastric cancer surgery. Ann Surg Oncol. 2017;24(2):510\u2013517.10.1245\/s10434-016-5548-x"},{"issue":"8","key":"b12","series-title":"Am Fam Physician","first-page":"1575","article-title":"Prealbumin: a marker for nutritional evaluation","volume":"65","author":"Beck FK","year":"2002","unstructured":"Beck FK, Rosenthal TC. Prealbumin: a marker for nutritional evaluation. Am Fam Physician. 2002;65(8):1575\u20131578."},{"issue":"12","key":"b13","series-title":"Clin Chem Lab Med","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1515\/CCLM.2002.232","article-title":"Transthyretin: its response to malnutrition and stress injury. clinical usefulness and economic implications","volume":"40","author":"Bernstein LH","year":"2002","unstructured":"Bernstein LH, Ingenbleek Y. Transthyretin: its response to malnutrition and stress injury. clinical usefulness and economic implications. Clin Chem Lab Med. 2002;40(12):1344\u20131348.10.1515\/CCLM.2002.232"},{"issue":"Suppl 3","key":"b14","series-title":"Intern Emerg Med","doi-asserted-by":"publisher","first-page":"S193","DOI":"10.1007\/s11739-012-0802-0","article-title":"Hypoalbuminemia","volume":"7","author":"Gatta A","year":"2012","unstructured":"Gatta A, Verardo A, Bolognesi MJ. Hypoalbuminemia. Intern Emerg Med. 2012;7Suppl 3:S193-S199.10.1007\/s11739-012-0802-0"},{"issue":"6","key":"b15","series-title":"J Clin Med","doi-asserted-by":"publisher","first-page":"775","DOI":"10.3390\/jcm8060775","article-title":"Nutritional laboratory markers in malnutrition","volume":"8","author":"Keller U","year":"2019","unstructured":"Keller U. Nutritional laboratory markers in malnutrition. J Clin Med. 2019;8(6):775.10.3390\/jcm8060775"},{"issue":"7","key":"b16","series-title":"JPEN J Parenter Enteral Nutr","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1177\/0148607114536735","article-title":"Impact of preoperative prealbumin on outcomes after cardiac surgery","volume":"39","author":"Yu P","year":"2015","unstructured":"Yu P, Cassiere H, Dellis S,  Impact of preoperative prealbumin on outcomes after cardiac surgery. JPEN J Parenter Enteral Nutr. 2015;39(7):870\u2013874.10.1177\/0148607114536735"},{"issue":"4 Special","key":"b17","series-title":"Pak J Pharm Sci","first-page":"1613","article-title":"Significance of retinol binding protein and prealbumin in neonatal nutritional evaluation","volume":"31","author":"Zhang Y","year":"2018","unstructured":"Zhang Y, Zhang M, Yang X,  Significance of retinol binding protein and prealbumin in neonatal nutritional evaluation. Pak J Pharm Sci. 2018;31(4 Special):1613\u20131616."},{"issue":"3","key":"b18","series-title":"Pituitary","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1007\/s11102-020-01112-5","article-title":"Pre-operative serum inflammation-based scores in patients with pituitary adenomas","volume":"24","author":"Marques P","year":"2021","unstructured":"Marques P, de Vries F, Dekkers OM,  Pre-operative serum inflammation-based scores in patients with pituitary adenomas. Pituitary. 2021;24(3):334\u2013350.10.1007\/s11102-020-01112-5"},{"issue":"3","key":"b19","series-title":"Endocrine","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1007\/s12020-020-02554-4","article-title":"Impact of age on postsurgical outcomes of nonfunctioning pituitary adenomas","volume":"72","author":"Biamonte E","year":"2021","unstructured":"Biamonte E, Betella N, Milani D,  Impact of age on postsurgical outcomes of nonfunctioning pituitary adenomas. Endocrine. 2021;72(3):915\u2013922.10.1007\/s12020-020-02554-4"},{"issue":"3","key":"b20","series-title":"Pituitary","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1007\/s11102-020-01108-1","article-title":"Cephalocaudal tumor diameter is a predictor of diabetes insipidus after endoscopic transsphenoidal surgery for non-functioning pituitary adenoma","volume":"24","author":"Oh H","year":"2021","unstructured":"Oh H, Cheun H, Kim YJ,  Cephalocaudal tumor diameter is a predictor of diabetes insipidus after endoscopic transsphenoidal surgery for non-functioning pituitary adenoma. Pituitary. 2021;24(3):303\u2013311.10.1007\/s11102-020-01108-1"},{"key":"b21","series-title":"Br J Neurosurg","article-title":"Subclinical hemorrhagic nonfunctionning pituitary adenoma: pituitary gland function status, endoscopic endonasal transsphenoidal surgery, and outcomes","author":"Wang M","unstructured":"Wang M, Jiang Y, Cai Y, Wu H, Peng Y. Subclinical hemorrhagic nonfunctionning pituitary adenoma: pituitary gland function status, endoscopic endonasal transsphenoidal surgery, and outcomes. Br J Neurosurg. Published online September 8, 2020. doi:10.1080\/02688697.2020.1815651"},{"issue":"4","key":"b22","series-title":"Curr Opin Pediatr","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1097\/MOP.0000000000000779","article-title":"Diagnosis and management of hypopituitarism","volume":"31","author":"Yeliosof O","year":"2019","unstructured":"Yeliosof O, Gangat M. Diagnosis and management of hypopituitarism. Curr Opin Pediatr. 2019;31(4):531\u2013536.10.1097\/MOP.0000000000000779"},{"issue":"10058","key":"b23","series-title":"Lancet","doi-asserted-by":"publisher","first-page":"2403","DOI":"10.1016\/S0140-6736(16)30053-8","article-title":"Hypopituitarism","volume":"388","author":"Higham CE","year":"2016","unstructured":"Higham CE, Johannsson G, Shalet SM. Hypopituitarism. Lancet. 2016;388(10058):2403\u20132415.10.1016\/S0140-6736(16)30053-8"},{"key":"b24","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"e851","DOI":"10.1016\/j.wneu.2017.11.125","article-title":"Risk factors and microbiology of meningitis and\/or bacteremia after transsphenoidal surgery for pituitary adenoma","volume":"110","author":"Jin Y","year":"2018","unstructured":"Jin Y, Liu X, Gao L,  Risk factors and microbiology of meningitis and\/or bacteremia after transsphenoidal surgery for pituitary adenoma. World Neurosurg. 2018;110:e851\u2013e863.10.1016\/j.wneu.2017.11.125"},{"issue":"2","key":"b25","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E5","DOI":"10.3171\/2019.5.FOCUS19269","article-title":"Risk factors for postoperative intracranial infections in patients with pituitary adenoma after endoscopic endonasal transsphenoidal surgery: pneumocephalus deserves further study","volume":"47","author":"Guo K","year":"2019","unstructured":"Guo K, Heng L, Zhang H, Ma L, Zhang H, Jia D. Risk factors for postoperative intracranial infections in patients with pituitary adenoma after endoscopic endonasal transsphenoidal surgery: pneumocephalus deserves further study. Neurosurg Focus. 2019;47(2):E5.10.3171\/2019.5.FOCUS19269"},{"issue":"1","key":"b26","series-title":"J Maxillofac Oral Surg","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1007\/s12663-018-1105-4","article-title":"Assessment of severity of illness and monitoring response to treatment of odontogenic space infection using serum prealbumin","volume":"18","author":"Adeosun PO","year":"2019","unstructured":"Adeosun PO, Fatusi OA, Adedeji TA. Assessment of severity of illness and monitoring response to treatment of odontogenic space infection using serum prealbumin. J Maxillofac Oral Surg. 2019;18(1):106\u2013111.10.1007\/s12663-018-1105-4"},{"issue":"2","key":"b27","series-title":"Int J Environ Res Public Health","doi-asserted-by":"publisher","first-page":"514","DOI":"10.3390\/ijerph8020514","article-title":"Hospital malnutrition: prevalence, identification and impact on patients and the healthcare system","volume":"8","author":"Barker LA","year":"2011","unstructured":"Barker LA, Gout BS, Crowe TC. Hospital malnutrition: prevalence, identification and impact on patients and the healthcare system. Int J Environ Res Public Health. 2011;8(2):514\u2013527.10.3390\/ijerph8020514"},{"issue":"4","key":"b28","series-title":"Neurosurg Clin N Am","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.nec.2019.05.011","article-title":"Sodium perturbations after pituitary surgery","volume":"30","author":"Yuen KCJ","year":"2019","unstructured":"Yuen KCJ, Ajmal A, Correa R, Little AS. Sodium perturbations after pituitary surgery. Neurosurg Clin N Am. 2019;30(4):515\u2013524.10.1016\/j.nec.2019.05.011"},{"issue":"4","key":"b29","series-title":"J Clin Med","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.3390\/jcm3041199","article-title":"Incidence, etiology and outcomes of hyponatremia after transsphenoidal surgery: experience with 344 consecutive patients at a single tertiary center","volume":"3","author":"Barber S","year":"2014","unstructured":"Barber S, Liebelt B, Baskin DJJ. Incidence, etiology and outcomes of hyponatremia after transsphenoidal surgery: experience with 344 consecutive patients at a single tertiary center. J Clin Med. 2014;3(4):1199\u20131219.10.3390\/jcm3041199"},{"key":"b30","series-title":"Kidney Int Suppl","first-page":"S12","article-title":"Severe hyponatremia after transsphenoidal surgery for pituitary adenomas","volume":"64","author":"Boehnert M","year":"1998","unstructured":"Boehnert M, Hensen J, Henig A, Fahlbusch R, Gross P, Buchfelder M. Severe hyponatremia after transsphenoidal surgery for pituitary adenomas. Kidney Int Suppl. 1998;64:S12\u2013S14."},{"issue":"5","key":"b31","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1093\/neuros\/nyaa148","article-title":"Diabetes insipidus after endoscopic transsphenoidal surgery","volume":"87","author":"Burke WT","year":"2020","unstructured":"Burke WT, Cote DJ, Penn DL, Iuliano S, McMillen K, Laws ER. Diabetes insipidus after endoscopic transsphenoidal surgery. Neurosurgery. 2020;87(5):949\u2013955.10.1093\/neuros\/nyaa148"}],"container-title":["Neurosurgical Focus"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/neurosurg-focus\/53\/6\/article-pE6.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/neurosurg-focus\/53\/6\/article-pE6.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/neurosurg-focus\/53\/6\/article-pE6.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T08:28:07Z","timestamp":1780129687000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/neurosurg-focus\/53\/6\/article-pE6.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":62,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/2022.9.focus22211","relation":{},"ISSN":["1092-0684"],"issn-type":[{"value":"1092-0684","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12]]}}}