{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T12:28:58Z","timestamp":1750681738102,"version":"3.28.2"},"reference-count":20,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>Patients with pulsatile tinnitus (PT) are often referred for digital subtraction angiography (DSA) to exclude cranial dural arteriovenous fistula (DAVF). Because DSA is not without risk, the authors studied the sensitivity and specificity of an automated detection algorithm that analyses external ear canal sound measurements to evaluate the presence of DAVF in PT patients.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>Between 2015 and 2021, external ear canal sound measurements of 72 PT patients were collected prospectively at our tertiary tinnitus clinic preceding referral of these patients to the neurosurgical department for counseling about DSA. The measurements were analyzed with an algorithm that objectifies a pulsatile sound as a PT coherence index (PTCI) per frequency band.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Ultimately, DSA was performed in 49 PT patients. DAVF was revealed in 15 patients (31%). PTCI cutoff values of 0.7 (at 250 Hz) and 0.6 (at 1000 Hz) resulted in sensitivity of 100% (78%\u2013100%) and specificities of 62% (44%\u201378%) and 68% (49%\u201383%), respectively, for detecting DAVF on DSA.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>Analysis of external ear canal sound measurements in PT patients showed 100% sensitivity for detecting DAVF on DSA. This analysis can potentially be used as a screening tool to help clinicians and PT patients to decide on the necessity of DSA. Retrospectively, the use of sound measurement in our cohort would have narrowed the indication for DSA to 23 of 49 cases (47%) without missing a DAVF.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2023.10.jns231255","type":"journal-article","created":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T01:22:56Z","timestamp":1702084976000},"page":"1700-1706","source":"Crossref","is-referenced-by-count":1,"title":["Performance of ear canal sound measurements in detecting dural arteriovenous fistulas"],"prefix":"10.3171","volume":"140","author":[{"given":"Sander W. J.","family":"Ubbink","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\/Head and Neck Surgery,"},{"name":"Graduate School of Medical Sciences (Behavioral Cognitive Neuroscience), and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Marc C.","family":"van Dijk","sequence":"additional","affiliation":[{"name":"Graduate School of Medical Sciences (Behavioral Cognitive Neuroscience), and"},{"name":"Department of Neurosurgery, University of Groningen, University Medical Center, Groningen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rutger","family":"Hofman","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\/Head and Neck Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pim","family":"van Dijk","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\/Head and Neck Surgery,"},{"name":"Graduate School of Medical Sciences (Behavioral Cognitive Neuroscience), and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"suppl","key":"b1","series-title":"Otolaryngol Head Neck Surg","first-page":"144","article-title":"Neuroradiologic assessment of pulsatile tinnitus","volume":"139","author":"Kircher ML","year":"2008","unstructured":"Kircher ML, Standring RT, Leonetti JP. Neuroradiologic assessment of pulsatile tinnitus. Otolaryngol Head Neck Surg. 2008;139(suppl):144."},{"issue":"3","key":"b2","series-title":"J Speech Hear Disord","first-page":"439","article-title":"Characterization of tinnitus by tinnitus patients","volume":"55","author":"Stouffer JL","year":"1990","unstructured":"Stouffer JL, Tyler RS. Characterization of tinnitus by tinnitus patients. J Speech Hear Disord. 1990;55(3):439-453."},{"issue":"6","key":"b3","series-title":"J Assoc Res Otolaryngol","first-page":"609","article-title":"Too blind to see the elephant? Why neuroscientists ought to be interested in tinnitus","volume":"22","author":"Knipper M","year":"2021","unstructured":"Knipper M, Mazurek B, van Dijk P, Schulze H. Too blind to see the elephant? Why neuroscientists ought to be interested in tinnitus. 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