{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,20]],"date-time":"2025-07-20T03:45:43Z","timestamp":1752983143708,"version":"3.30.1"},"reference-count":50,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>Leiomyosarcoma (LMS) is a rare, aggressive soft-tissue sarcoma that seldom spreads to the bone. The spine can be either the site of LMS osseous metastases or the primary tumor site. The optimal treatment option for spinal LMS is still unclear. The authors present a cohort of patients with spinal LMS treated with either upfront surgery or upfront CyberKnife stereotactic radiosurgery (SRS).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>The authors retrospectively studied the clinical and radiological outcomes of 17 patients with spinal LMS treated at their institution between 2004 and 2020. Either surgery or SRS was used as the upfront treatment. The clinical and radiological outcomes were assessed. A systematic review of the literature was also conducted.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Of the 17 patients (20 spinal lesions), 12 (70.6%) were female. The median patient age was 61 years (range 41\u201380 years). Ten patients had upfront surgery for their spinal lesions, and 7 had upfront CyberKnife radiosurgery. The median follow-up was 11 months (range 0.3\u2013130 months). The median overall survival (OS) for the entire cohort was 13 months (range 0.3\u201397 months). In subgroup analysis, the median OS was lower for the surgical group (13 months, range 0.3\u201350 months), while the median OS for the SRS group was 15 months (range 5\u201397 months) (p = 0.5). Forty percent (n = 4) of those treated with surgery presented with local recurrence at a median of 6.7 months (range 0.3\u201336 months), while only 14% (n = 1) of those treated with CyberKnife radiosurgery had local recurrence after 5 months. Local tumor control (LTC) rates at the 6-, 12-, and 18-month follow-ups were 72%, 58%, and 43%, respectively, for the SRS group and 40%, 30%, and 20%, respectively, for the surgery group (p &lt; 0.05). The literature review included 35 papers with 70 patients harboring spinal LMS; only 2 patients were treated with SRS. The literature review confirms the clinical and radiological outcomes of the surgical group, while data on SRS are anecdotal.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>The authors present the largest series in the literature of spinal LMS and the first on SRS for spinal LMS. This study shows that LTC is statistically significantly better in patients receiving upfront SRS instead of surgery. The OS does not appear different between the two groups.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2023.10.spine23666","type":"journal-article","created":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T01:44:34Z","timestamp":1703900674000},"page":"485-497","source":"Crossref","is-referenced-by-count":1,"title":["Surgery and stereotactic radiosurgery for spinal leiomyosarcoma: a single-institution retrospective series and systematic review"],"prefix":"10.3171","volume":"40","author":[{"given":"Aroosa","family":"Zamarud","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neelan J.","family":"Marianayagam","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vashisht","family":"Sekar","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Testa","sequence":"additional","affiliation":[{"name":"Medicine, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Park","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulas","family":"Yener","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamra-Lee","family":"McCleary","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly H.","family":"Yoo","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Emrich","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armine","family":"Tayag","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louisa","family":"Ustrzynski","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erqi","family":"Pollom","sequence":"additional","affiliation":[{"name":"Radiation Oncology,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Soltys","sequence":"additional","affiliation":[{"name":"Radiation Oncology,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[{"name":"Radiation Oncology,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg","family":"Charville","sequence":"additional","affiliation":[{"name":"Pathology, Stanford University, Stanford, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen","family":"Ganjoo","sequence":"additional","affiliation":[{"name":"Medicine, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven D.","family":"Chang","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Meola","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"2","key":"b1","series-title":"Arch Bone Jt Surg","first-page":"106","article-title":"Prevalence of malignant soft tissue tumors in extremities: an epidemiological study in syria","volume":"2","author":"Reshadi H","year":"2014","unstructured":"Reshadi H, Rouhani A, Mohajerzadeh S, Moosa M, Elmi A. Prevalence of malignant soft tissue tumors in extremities: an epidemiological study in syria. Arch Bone Jt Surg. 2014;2(2):106\u2013110."},{"key":"b2","article-title":"StatPearls","author":"Mangla A","year":"2022","unstructured":"Mangla A, Yadav U. Leiomyosarcoma. In: StatPearls. StatPearls Publishing;2022.Accessed October 25, 2023.https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK551667\/"},{"key":"b3","series-title":"Sarcoma","first-page":"6806932","article-title":"Bone metastases in patients with leiomyosarcoma: a retrospective analysis of survival and surgical management","volume":"2022","author":"LiBrizzi CL","year":"2022","unstructured":"LiBrizzi CL, Vankara A, Meyer CF, Levin AS, Morris CD. Bone metastases in patients with leiomyosarcoma: a retrospective analysis of survival and surgical management. Sarcoma. 2022;2022:6806932."},{"issue":"4","key":"b4","series-title":"J Gynecol Oncol","first-page":"306","article-title":"Metastatic pattern of uterine leiomyosarcoma: retrospective analysis of the predictors and outcome in 113 patients","volume":"25","author":"Tirumani SH","year":"2014","unstructured":"Tirumani SH, Deaver P, Shinagare AB,  Metastatic pattern of uterine leiomyosarcoma: retrospective analysis of the predictors and outcome in 113 patients. J Gynecol Oncol. 2014;25(4):306\u2013312."},{"issue":"2","key":"b5","series-title":"J Neurosurg Spine","first-page":"178","article-title":"Leiomyosarcoma metastases to the spine. Case series and review of the literature","volume":"6","author":"Elhammady MS","year":"2007","unstructured":"Elhammady MS, Manzano GR, Lebwohl N, Levi AD. Leiomyosarcoma metastases to the spine. Case series and review of the literature. J Neurosurg Spine. 2007;6(2):178\u2013183."},{"issue":"4","key":"b6","series-title":"World J Oncol","first-page":"182","article-title":"Metastatic leiomyosarcoma to the spine complicated with thrombocytopenia","volume":"3","author":"Shirzadi A","year":"2012","unstructured":"Shirzadi A, Drazin D, Shirzadi N,  Metastatic leiomyosarcoma to the spine complicated with thrombocytopenia. World J Oncol. 2012;3(4):182\u2013186."},{"issue":"1","key":"b7","series-title":"J Neurosurg Spine","first-page":"131","article-title":"Postoperative survival and functional outcomes for patients with metastatic gynecological cancer to the spine: case series and review of the literature","volume":"24","author":"Liu A","year":"2016","unstructured":"Liu A, Sankey EW, Goodwin CR,  Postoperative survival and functional outcomes for patients with metastatic gynecological cancer to the spine: case series and review of the literature. J Neurosurg Spine. 2016;24(1):131\u2013144."},{"issue":"7","key":"b8","series-title":"Am J Clin Oncol","first-page":"681","article-title":"Outcome after surgery for extremity soft tissue sarcoma in patients presenting with metastasis at diagnosis","volume":"41","author":"Krishnan CK","year":"2018","unstructured":"Krishnan CK, Kim HS, Park JW, Han I. Outcome after surgery for extremity soft tissue sarcoma in patients presenting with metastasis at diagnosis. Am J Clin Oncol. 2018;41(7):681\u2013686."},{"issue":"4","key":"b9","series-title":"J Neurosurg Spine","first-page":"409","article-title":"Stereotactic radiosurgery for spinal metastases with or without separation surgery","volume":"22","author":"Bate BG","year":"2015","unstructured":"Bate BG, Khan NR, Kimball BY, Gabrick K, Weaver J. Stereotactic radiosurgery for spinal metastases with or without separation surgery. J Neurosurg Spine. 2015;22(4):409\u2013415."},{"issue":"6","key":"b10","series-title":"Oncologist","first-page":"744","article-title":"The NOMS framework: approach to the treatment of spinal metastatic tumors","volume":"18","author":"Laufer I","year":"2013","unstructured":"Laufer I, Rubin DG, Lis E,  The NOMS framework: approach to the treatment of spinal metastatic tumors. Oncologist. 2013;18(6):744\u2013751."},{"issue":"1","key":"b11","series-title":"J Neurosurg Spine","first-page":"87","article-title":"Local disease control after decompressive surgery and adjuvant high-dose single-fraction radiosurgery for spine metastases","volume":"13","author":"Moulding HD","year":"2010","unstructured":"Moulding HD, Elder JB, Lis E,  Local disease control after decompressive surgery and adjuvant high-dose single-fraction radiosurgery for spine metastases. J Neurosurg Spine. 2010;13(1):87\u201393."},{"issue":"22","key":"b12","series-title":"Spine (Phila Pa 1976)","first-page":"E1221","article-title":"A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine Oncology Study Group","volume":"35","author":"Fisher CG","year":"2010","unstructured":"Fisher CG, DiPaola CP, Ryken TC,  A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine Oncology Study Group. Spine (Phila Pa 1976). 2010;35(22):E1221\u2013E1229."},{"issue":"1","key":"b13","series-title":"J Neurosurg Spine","first-page":"87","article-title":"Local control and toxicity outcomes of stereotactic radiosurgery for spinal metastases of gastrointestinal origin","volume":"33","author":"Sandhu N","year":"2020","unstructured":"Sandhu N, Benson KRK, Kumar KA,  Local control and toxicity outcomes of stereotactic radiosurgery for spinal metastases of gastrointestinal origin. J Neurosurg Spine. 2020;33(1):87\u201394."},{"issue":"2","key":"b14","series-title":"J Neurosurg Spine","first-page":"172","article-title":"Total en bloc spondylectomy for spinal metastases in thyroid carcinoma","volume":"14","author":"Demura S","year":"2011","unstructured":"Demura S, Kawahara N, Murakami H,  Total en bloc spondylectomy for spinal metastases in thyroid carcinoma. J Neurosurg Spine. 2011;14(2):172\u2013176."},{"issue":"9486","key":"b15","series-title":"Lancet","first-page":"643","article-title":"Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial","volume":"366","author":"Patchell RA","year":"2005","unstructured":"Patchell RA, Tibbs PA, Regine WF,  Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet. 2005;366(9486):643\u2013648."},{"issue":"71","key":"b16","series-title":"BMJ","first-page":"n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page MJ","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM,  The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. 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Neuroradiology. 1995;37(6):465\u2013467."},{"issue":"10","key":"b19","series-title":"Spine (Phila Pa 1976).","first-page":"987","article-title":"Spinal manifestation of metastasizing leiomyosarcoma","volume":"24","author":"Nanassis K","year":"1999","unstructured":"Nanassis K, Alexiadou-Rudolf C, Tsitsopoulos P. Spinal manifestation of metastasizing leiomyosarcoma. Spine (Phila Pa 1976).1999;24(10):987\u2013989."},{"issue":"1","key":"b20","series-title":"Neuropathology","first-page":"60","article-title":"Primary leiomyosarcoma of the cervical spine causing spontaneous compression fracture: report of an autopsy case","volume":"20","author":"Ochiai H","year":"2000","unstructured":"Ochiai H, Yamakawa Y, Fukushima T, Yamada H, Hayashi T. Primary leiomyosarcoma of the cervical spine causing spontaneous compression fracture: report of an autopsy case. Neuropathology. 2000;20(1):60\u201364."},{"issue":"2","key":"b21","series-title":"Spine (Phila Pa 1976)","first-page":"E42","article-title":"Leiomyosarcoma of the lumbar spine: case report","volume":"27","author":"Nishida J","year":"2002","unstructured":"Nishida J, Kato S, Shiraishi H,  Leiomyosarcoma of the lumbar spine: case report. Spine (Phila Pa 1976). 2002;27(2):E42\u2013E46."},{"issue":"12","key":"b22","series-title":"Spine (Phila Pa 1976)","first-page":"E301","article-title":"Thoracic paravertebral leiomyosarcoma: rare but it does occur","volume":"27","author":"Aksoy DY","year":"2002","unstructured":"Aksoy DY, Altundag MK, Durusu M,  Thoracic paravertebral leiomyosarcoma: rare but it does occur. Spine (Phila Pa 1976). 2002;27(12):E301\u2013E303."},{"issue":"3","key":"b23","series-title":"J Clin Neurosci","first-page":"325","article-title":"Paraparesis due to spinal leiomyosarcoma lesion in the thoracic spine accompanied by two leiomyosarcoma lesions in the back and the thigh over an interval of 4 years","volume":"9","author":"Ido K","year":"2002","unstructured":"Ido K, Matsuoka H, Yoshida M, Urushidani H. Paraparesis due to spinal leiomyosarcoma lesion in the thoracic spine accompanied by two leiomyosarcoma lesions in the back and the thigh over an interval of 4 years. J Clin Neurosci. 2002;9(3):325\u2013328."},{"issue":"1","key":"b24","series-title":"Pathol Int","first-page":"73","article-title":"Primary leiomyosarcoma of the vertebra: case report and review of the literature","volume":"54","author":"Sasaguri T","year":"2004","unstructured":"Sasaguri T, Tanimoto A, Kimura S,  Primary leiomyosarcoma of the vertebra: case report and review of the literature. Pathol Int. 2004;54(1):73\u201376."},{"issue":"2","key":"b25","series-title":"Neurosurgery","first-page":"E372","article-title":"Primary extradural epithelioid leiomyosarcoma of the cervical spine: case report and literature review","volume":"57","author":"Marshman LA","year":"2005","unstructured":"Marshman LA, Pollock JR, King A, Chawda SJ. Primary extradural epithelioid leiomyosarcoma of the cervical spine: case report and literature review. Neurosurgery. 2005;57(2):E372."},{"issue":"5","key":"b26","series-title":"J Neurosurg Spine","first-page":"441","article-title":"Primary paraspinal leiomyosarcoma invading the cervical spinal canal successfully treated with surgery, radiotherapy, and chemotherapy. Case report","volume":"6","author":"Lehman NL","year":"2007","unstructured":"Lehman NL, Jacobs CD, Holsten PA,  Primary paraspinal leiomyosarcoma invading the cervical spinal canal successfully treated with surgery, radiotherapy, and chemotherapy. Case report. 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J Clin Neurosci. 2013;20(9):1309\u20131312."},{"issue":"1","key":"b31","series-title":"Oncol Lett","first-page":"263","article-title":"Leiomyosarcoma metastatic to the cervical spine causing a C6 compression fracture: a case report","volume":"8","author":"Sun Z","year":"2014","unstructured":"Sun Z, Wang H, Yang H, Jiang W. Leiomyosarcoma metastatic to the cervical spine causing a C6 compression fracture: a case report. Oncol Lett. 2014;8(1):263\u2013265."},{"issue":"5","key":"b32","series-title":"J Neurosurg Spine","first-page":"607","article-title":"Treatment of recurrent metastatic uterine leiomyosarcoma of the spine: a multimodality approach using resection, radiosurgery, and chemotherapy","volume":"23","author":"Strong MJ","year":"2015","unstructured":"Strong MJ, Rosenlof T, Padmanabha S, Weiner RS, Morgan LR, Ware MI. Treatment of recurrent metastatic uterine leiomyosarcoma of the spine: a multimodality approach using resection, radiosurgery, and chemotherapy. J Neurosurg Spine. 2015;23(5):607\u2013612."},{"issue":"6","key":"b33","series-title":"Interv Neuroradiol","first-page":"742","article-title":"Delayed vertebral body collapse after stereotactic radiosurgery and radiofrequency ablation: case report with histopathologic-MRI correlation","volume":"21","author":"Wallace AN","year":"2015","unstructured":"Wallace AN, Vyhmeister R, Hsi AC, Robinson CG, Chang RO, Jennings JW. Delayed vertebral body collapse after stereotactic radiosurgery and radiofrequency ablation: case report with histopathologic-MRI correlation. Interv Neuroradiol. 2015;21(6):742\u2013749."},{"issue":"2","key":"b34","series-title":"Clin Neuroradiol","first-page":"229","article-title":"MR imaging findings of a leiomyosarcoma of the thoracic spine: a case report","volume":"26","author":"Tahara K","year":"2016","unstructured":"Tahara K, Yamashita K, Hiwatashi A,  MR imaging findings of a leiomyosarcoma of the thoracic spine: a case report. 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Eur Spine J. 2019;28(suppl 2):41-50."},{"issue":"4","key":"b42","series-title":"J Spinal Cord Med","first-page":"643","article-title":"Primary leiomyosarcoma of cervical spine invading the vertebra without obvious osteoclasia: case report and literature review","volume":"45","author":"Sun H","year":"2022","unstructured":"Sun H, Zhuang M, Cheng D, Zhu C, Liu Z, Qiu X. Primary leiomyosarcoma of cervical spine invading the vertebra without obvious osteoclasia: case report and literature review. J Spinal Cord Med. 2022;45(4):643\u2013647."},{"issue":"1","key":"b43","series-title":"Korean J Gastroenterol","first-page":"57","article-title":"Synchronous primary leiomyosarcoma in the thoracic vertebra and the liver","volume":"74","author":"Kim YK","year":"2019","unstructured":"Kim YK, Kim JA, Ryu SH,  Synchronous primary leiomyosarcoma in the thoracic vertebra and the liver. 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