{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:13:52Z","timestamp":1791386032233,"version":"4.3.3"},"reference-count":37,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>This study aimed to investigate the impact of pelvic incidence (PI) and lumbar lordosis (LL) matching on health-related quality of life (HRQOL) outcomes in patients undergoing one- or two-level lumbar fusions for degenerative pathology. The study also examined changes in alignment and HRQOL over a 24-month follow-up period.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>A retrospective cohort study used data from a multicenter, prospectively collected database. Radiographic parameters were measured preoperatively and at 3-month and 24-month postoperative time points. Patients were categorized as having alignment (PI-LL \u2264 10\u00b0) or malalignment (PI-LL &gt; 10\u00b0) at all time points. The Oswestry Disability Index scores were collected at the same time points. Statistical analyses assessed differences in HRQOL scores and radiographic parameters between the aligned and malaligned groups.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Seventy-six patients were included. Both the aligned and malaligned groups showed improved HRQOL scores after surgery, but patients with proper alignment (PI-LL \u2264 10\u00b0) had significantly better HRQOL scores at the 24-month follow-up. Alignment remained stable from 3 months to 24 months postoperatively, with minimal movement between the aligned and malaligned groups.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>Proper PI-LL matching in one- and two-level lumbar fusions for degenerative pathology leads to improved HRQOL outcomes at the 24-month follow-up. Patients with maintained proper alignment after surgery experience continued improvement in disability levels. Surgeons should consider longer follow-up for patients who do not achieve proper alignment initially, as 24 months is crucial for assessing the consequences of malalignment in short-segment lumbar fusions.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2023.10.spine23689","type":"journal-article","created":{"date-parts":[[2024,1,6]],"date-time":"2024-01-06T04:14:11Z","timestamp":1704514451000},"page":"412-419","source":"Crossref","is-referenced-by-count":9,"title":["Is spinopelvic mismatch associated with increased disability at 2 years following short-segment lumbar fusions?"],"prefix":"10.3171","volume":"40","author":[{"given":"Devon","family":"LeFever","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Center for Neurosciences and Spine, Virginia Mason Franciscan Health, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip K.","family":"Louie","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Center for Neurosciences and Spine, Virginia Mason Franciscan Health, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aiyush","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Center for Neurosciences and Spine, Virginia Mason Franciscan Health, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Drolet","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Center for Neurosciences and Spine, Virginia Mason Franciscan Health, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venu M.","family":"Nemani","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Center for Neurosciences and Spine, Virginia Mason Franciscan Health, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Christophe","family":"Leveque","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Center for Neurosciences and Spine, Virginia Mason Franciscan Health, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"12","key":"b1","series-title":"Spine (Phila Pa 1976)","first-page":"1077","article-title":"Scoliosis Research Society\u2013Schwab adult spinal deformity classification: a validation study","volume":"37","author":"Schwab F","year":"2012","unstructured":"Schwab F, Ungar B, Blondel B,  Scoliosis Research Society\u2013Schwab adult spinal deformity classification: a validation study. 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