{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T01:54:18Z","timestamp":1793498058600,"version":"4.5.0"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>Low-field portable MRI (pMRI) is a recent technological advancement with potential for broad applications. Compared with conventional MRI, pMRI is less resource-intensive with regard to operational costs and scan time. The application of pMRI in neurosurgical oncology has not been previously described. The goal of this study was to demonstrate the efficacy of pMRI in assessing optic nerve decompression after endoscopic endonasal surgery for sellar and suprasellar pathologies.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>Patients who underwent endoscopic endonasal surgery for sellar and suprasellar lesions at a single institution and for whom pMRI and routine MRI were performed postoperatively were retrospectively reviewed to compare the two imaging systems. To assess the relative resolution of pMRI compared with MRI, the distance from the optic chiasm to the top of the third ventricle was measured, and the measurements were compared between paired equivalent slices on T2-weighted coronal images. The inter- and intrarater correlations were analyzed.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Twelve patients were included in this study (10 with pituitary adenomas and 2 with craniopharyngiomas) with varying degrees of optic chiasm compression on preoperative imaging. Measurements were averaged across raters before calculating agreement between pMRI and MRI, which demonstrated significant interrater reliability (intraclass correlation coefficient [ICC] = 0.78, p &lt; 0.01). Agreement between raters within the pMRI measurements was also significantly reliable (ICC = 0.93, p &lt; 0.01). Finally, a linear mixed-effects model was specified to demonstrate that MRI measurement could be predicted using the pMRI measurement with the patient and rater set as random effects (pMRI \u03b2 coefficient = 0.80, p &lt; 0.01).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>The results of this study suggest that resolution of pMRI is comparable to that of conventional MRI in assessing the optic chiasm position in relation to the third ventricle. Portable MRI sufficiently demonstrates decompression of the optic chiasm after endoscopic endonasal surgery. It can be an alternative strategy in cases in which cost, scan-time considerations, or lack of intraoperative MRI availability may preclude the ability to assess adequate optic nerve decompression after endoscopic endonasal surgery for sellar and suprasellar lesions.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2023.5.jns23174","type":"journal-article","created":{"date-parts":[[2023,6,18]],"date-time":"2023-06-18T09:02:51Z","timestamp":1687078971000},"page":"1664-1670","source":"Crossref","is-referenced-by-count":8,"title":["Portable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions"],"prefix":"10.3171","volume":"139","author":[{"given":"Christopher S.","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Yale School of Medicine, New Haven;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Layton A.","family":"Lamsam","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Yale School of Medicine, New Haven;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vineetha","family":"Yadlapalli","sequence":"additional","affiliation":[{"name":"Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale School of Medicine, New Haven;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nethra","family":"Parasuram","sequence":"additional","affiliation":[{"name":"Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale School of Medicine, New Haven;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercy","family":"Mazurek","sequence":"additional","affiliation":[{"name":"Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale School of Medicine, New Haven;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isha","family":"Chavva","sequence":"additional","affiliation":[{"name":"Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale School of Medicine, New Haven;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dheeraj","family":"Lalwani","sequence":"additional","affiliation":[{"name":"Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale School of Medicine, New Haven;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Zabinska","sequence":"additional","affiliation":[{"name":"Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale School of Medicine, New Haven;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Schiff","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Yale School of Medicine, New Haven;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Peter","family":"Manes","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology, Yale School of Medicine, New Haven, Connecticut; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenia M.","family":"Vining","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology, Yale School of Medicine, New Haven, Connecticut; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan A.","family":"Rimmer","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology, Yale School of Medicine, New Haven, Connecticut; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Taylor","family":"Kimberly","sequence":"additional","affiliation":[{"name":"Department of Neurology, Division of Neurocritical Care, Massachusetts General Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin N.","family":"Sheth","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Yale School of Medicine, New Haven;"},{"name":"Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale School of Medicine, New Haven;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sacit Bulent","family":"Omay","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Yale School of Medicine, New Haven;"},{"name":"Department of Surgery, Division of Otolaryngology, Yale School of Medicine, New Haven, Connecticut; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"16","key":"b1","series-title":"Sci Adv","first-page":"eabp9307","article-title":"Detection of stroke by portable, low-field MRI: a milestone in medical imaging","volume":"8","author":"Basser P","year":"2022","unstructured":"Basser P. Detection of stroke by portable, low-field MRI: a milestone in medical imaging. Sci Adv. 2022;8(16):eabp9307."},{"key":"b2","series-title":"Neuroimage","first-page":"118210","article-title":"Emerging ethical issues raised by highly portable MRI research in remote and resource-limited international settings","volume":"238","author":"Shen FX","year":"2021","unstructured":"Shen FX, Wolf SM, Bhavnani S,  Emerging ethical issues raised by highly portable MRI research in remote and resource-limited international settings. Neuroimage. 2021;238:118210."},{"issue":"1","key":"b3","series-title":"Nat Commun","first-page":"5119","article-title":"Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage","volume":"12","author":"Mazurek MH","year":"2021","unstructured":"Mazurek MH, Cahn BA, Yuen MM,  Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage. Nat Commun. 2021;12(1):5119."},{"issue":"16","key":"b4","series-title":"Sci Adv","first-page":"eabm3952","article-title":"Portable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic stroke","volume":"8","author":"Yuen MM","year":"2022","unstructured":"Yuen MM, Prabhat AM, Mazurek MH,  Portable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic stroke. Sci Adv. 2022;8(16):eabm3952."},{"issue":"4","key":"b5","series-title":"Neurosurgery","first-page":"799","article-title":"Novel, compact, intraoperative magnetic resonance imaging-guided system for conventional neurosurgical operating rooms","volume":"48","author":"Hadani M","year":"2001","unstructured":"Hadani M, Spiegelman R, Feldman Z, Berkenstadt H, Ram Z. Novel, compact, intraoperative magnetic resonance imaging-guided system for conventional neurosurgical operating rooms. Neurosurgery. 2001;48(4):799\u2013809."},{"issue":"5","key":"b6","series-title":"J Neurosurg","first-page":"1115","article-title":"Intracranial navigation by using low-field intraoperative magnetic resonance imaging: preliminary experience","volume":"97","author":"Kanner AA","year":"2002","unstructured":"Kanner AA, Vogelbaum MA, Mayberg MR, Weisenberger JP, Barnett GH. Intracranial navigation by using low-field intraoperative magnetic resonance imaging: preliminary experience. J Neurosurg. 2002;97(5):1115\u20131124."},{"issue":"2","key":"b7","series-title":"Childs Nerv Syst","first-page":"108","article-title":"Use of a compact intraoperative low-field magnetic imager in pediatric neurosurgery","volume":"21","author":"Samdani AF","year":"2005","unstructured":"Samdani AF, Schulder M, Catrambone JE, Carmel PW. Use of a compact intraoperative low-field magnetic imager in pediatric neurosurgery. Childs Nerv Syst. 2005;21(2):108\u2013114."},{"issue":"1","key":"b8","series-title":"Neurosurgery","first-page":"63","article-title":"Transsphenoidal pituitary macroadenomas resection guided by PoleStar N20 low-field intraoperative magnetic resonance imaging: comparison with early postoperative high-field magnetic resonance imaging","volume":"65","author":"Wu JS","year":"2009","unstructured":"Wu JS, Shou XF, Yao CJ,  Transsphenoidal pituitary macroadenomas resection guided by PoleStar N20 low-field intraoperative magnetic resonance imaging: comparison with early postoperative high-field magnetic resonance imaging. Neurosurgery. 2009;65(1):63\u201371."},{"issue":"2","key":"b9","series-title":"J Magn Reson Imaging","first-page":"372","article-title":"Low-field MRI of stroke: challenges and opportunities","volume":"54","author":"Bhat SS","year":"2021","unstructured":"Bhat SS, Fernandes TT, Poojar P,  Low-field MRI of stroke: challenges and opportunities. J Magn Reson Imaging. 2021;54(2):372\u2013390."},{"key":"b10","series-title":"Mult Scler Relat Disord","first-page":"102903","article-title":"Low-field portable brain MRI in CNS demyelinating disease","volume":"51","author":"Mateen FJ","year":"2021","unstructured":"Mateen FJ, Cooley CZ, Stockmann JP, Rice DR, Vogel AC, Wald LL. Low-field portable brain MRI in CNS demyelinating disease. Mult Scler Relat Disord. 2021;51:102903."},{"issue":"4","key":"b11","series-title":"Neurosurg Clin N Am","first-page":"413","article-title":"Intraoperative MRI for pituitary adenomas","volume":"30","author":"Jones PS","year":"2019","unstructured":"Jones PS, Swearingen B. Intraoperative MRI for pituitary adenomas. Neurosurg Clin N Am. 2019;30(4):413\u2013420."},{"issue":"6","key":"b12","series-title":"J Neurol Surg B Skull Base","first-page":"646","article-title":"The value of intraoperative magnetic resonance imaging in endoscopic endonasal resection of pituitary adenoma","volume":"83","author":"Patel A","year":"2022","unstructured":"Patel A, Dastagirzada Y, Benjamin C,  The value of intraoperative magnetic resonance imaging in endoscopic endonasal resection of pituitary adenoma. J Neurol Surg B Skull Base. 2022;83(6):646\u2013652."},{"issue":"4","key":"b13","series-title":"Pituitary","first-page":"644","article-title":"Impact of intraoperative magnetic resonance imaging on gross total resection, extent of resection, and residual tumor volume in pituitary surgery: systematic review and meta-analysis","volume":"24","author":"Staartjes VE","year":"2021","unstructured":"Staartjes VE, Togni-Pogliorini A, Stumpo V, Serra C, Regli L. Impact of intraoperative magnetic resonance imaging on gross total resection, extent of resection, and residual tumor volume in pituitary surgery: systematic review and meta-analysis. Pituitary. 2021;24(4):644\u2013656."},{"issue":"3","key":"b14","series-title":"J Neurosurg","first-page":"518","article-title":"Intraoperative magnetic resonance imaging and early prognosis for vision after transsphenoidal surgery for sellar lesions","volume":"115","author":"Berkmann S","year":"2011","unstructured":"Berkmann S, Fandino J, Zosso S, Killer HE, Remonda L, Landolt H. Intraoperative magnetic resonance imaging and early prognosis for vision after transsphenoidal surgery for sellar lesions. J Neurosurg. 2011;115(3):518\u2013527."},{"issue":"2","key":"b15","series-title":"Pituitary","first-page":"155","article-title":"Transsphenoidal resection of pituitary adenomas in an intraoperative MRI unit","volume":"2","author":"Martin CH","year":"1999","unstructured":"Martin CH, Schwartz R, Jolesz F, Black PM. Transsphenoidal resection of pituitary adenomas in an intraoperative MRI unit. Pituitary. 1999;2(2):155\u2013162."},{"issue":"1","key":"b16","series-title":"J Magn Reson Imaging","first-page":"136","article-title":"Intra-operative MR guidance during trans-sphenoidal pituitary resection: preliminary results","volume":"13","author":"Pergolizzi RS Jr","year":"2001","unstructured":"Pergolizzi RS Jr, Nabavi A, Schwartz RB,  Intra-operative MR guidance during trans-sphenoidal pituitary resection: preliminary results. J Magn Reson Imaging. 2001;13(1):136\u2013141."},{"key":"b17","series-title":"World Neurosurg","first-page":"184","article-title":"Impact of intraoperative magnetic resonance imaging on short-term and long-term outcomes after transsphenoidal resection of pituitary adenoma: a systematic review and meta-analysis","volume":"167","author":"Zhang JJY","year":"2022","unstructured":"Zhang JJY, Lim JX, Lee KS, Kirollos RW, Rao JP. Impact of intraoperative magnetic resonance imaging on short-term and long-term outcomes after transsphenoidal resection of pituitary adenoma: a systematic review and meta-analysis. World Neurosurg. 2022;167:184\u2013194.e16."},{"issue":"4","key":"b18","series-title":"Acta Neurochir (Wien)","first-page":"639","article-title":"Intraoperative MRI and endocrinological outcome of transsphenoidal surgery for non-functioning pituitary adenoma","volume":"154","author":"Berkmann S","year":"2012","unstructured":"Berkmann S, Fandino J, M\u00fcller B, Remonda L, Landolt H. Intraoperative MRI and endocrinological outcome of transsphenoidal surgery for non-functioning pituitary adenoma. Acta Neurochir (Wien). 2012;154(4):639\u2013647."},{"issue":"1","key":"b19","series-title":"World Neurosurg","first-page":"99","article-title":"Impact of ultra-low-field intraoperative magnetic resonance imaging on extent of resection and frequency of tumor recurrence in 104 surgically treated nonfunctioning pituitary adenomas","volume":"79","author":"Hlavica M","year":"2013","unstructured":"Hlavica M, Bellut D, Lemm D, Schmid C, Bernays RL. Impact of ultra-low-field intraoperative magnetic resonance imaging on extent of resection and frequency of tumor recurrence in 104 surgically treated nonfunctioning pituitary adenomas. World Neurosurg. 2013;79(1):99\u2013109."},{"issue":"3","key":"b20","series-title":"Acta Neurochir (Wien)","first-page":"485","article-title":"Application of low-field intraoperative magnetic resonance imaging in transsphenoidal surgery for pituitary adenomas: technical points to improve the visibility of the tumor resection margin","volume":"155","author":"Kim EH","year":"2013","unstructured":"Kim EH, Oh MC, Kim SH. Application of low-field intraoperative magnetic resonance imaging in transsphenoidal surgery for pituitary adenomas: technical points to improve the visibility of the tumor resection margin. Acta Neurochir (Wien). 2013;155(3):485\u2013493."},{"issue":"4","key":"b21","series-title":"Acta Neurochir (Wien)","first-page":"325","article-title":"Visual recovery following optic nerve decompression for chronic compressive neuropathy","volume":"151","author":"Bulters DO","year":"2009","unstructured":"Bulters DO, Shenouda E, Evans BT, Mathad N, Lang DA. Visual recovery following optic nerve decompression for chronic compressive neuropathy. Acta Neurochir (Wien). 2009;151(4):325\u2013334."},{"key":"b22","series-title":"Prog Retin Eye Res","first-page":"100765","article-title":"Visual loss and recovery in chiasmal compression","volume":"73","author":"Danesh-Meyer HV","year":"2019","unstructured":"Danesh-Meyer HV, Yoon JJ, Lawlor M, Savino PJ. Visual loss and recovery in chiasmal compression. Prog Retin Eye Res. 2019;73:100765."},{"issue":"6","key":"b23","series-title":"J Neurosurg","first-page":"717","article-title":"Transsphenoidal decompression of the optic nerve and chiasm. Visual results in 62 patients","volume":"46","author":"Laws ER Jr","year":"1977","unstructured":"Laws ER Jr, Trautmann JC, Hollenhorst RW Jr. Transsphenoidal decompression of the optic nerve and chiasm. Visual results in 62 patients. J Neurosurg. 1977;46(6):717\u2013722."},{"issue":"3","key":"b24","series-title":"J Neurosurg","first-page":"381","article-title":"Intraoperative magnetic resonance imaging during transsphenoidal surgery","volume":"95","author":"Fahlbusch R","year":"2001","unstructured":"Fahlbusch R, Ganslandt O, Buchfelder M, Schott W, Nimsky C. Intraoperative magnetic resonance imaging during transsphenoidal surgery. J Neurosurg. 2001;95(3):381\u2013390."},{"issue":"2","key":"b25","series-title":"Eur J Endocrinol","first-page":"239","article-title":"Transsphenoidal surgery in acromegaly investigated by intraoperative high-field magnetic resonance imaging","volume":"153","author":"Fahlbusch R","year":"2005","unstructured":"Fahlbusch R, Keller Bv, Ganslandt O, Kreutzer J, Nimsky C. Transsphenoidal surgery in acromegaly investigated by intraoperative high-field magnetic resonance imaging. Eur J Endocrinol. 2005;153(2):239\u2013248."},{"issue":"5","key":"b26","series-title":"Neurosurg Focus","first-page":"E12","article-title":"Intraoperative magnetic resonance imaging in pituitary macroadenoma surgery: an assessment of visual outcome","volume":"23","author":"Jones J","year":"2007","unstructured":"Jones J, Ruge J. Intraoperative magnetic resonance imaging in pituitary macroadenoma surgery: an assessment of visual outcome. Neurosurg Focus. 2007;23(5):E12."},{"issue":"1","key":"b27","series-title":"Neurosurgery","first-page":"105","article-title":"Intraoperative high-field magnetic resonance imaging in transsphenoidal surgery of hormonally inactive pituitary macroadenomas","volume":"59","author":"Nimsky C","year":"2006","unstructured":"Nimsky C, von Keller B, Ganslandt O, Fahlbusch R. Intraoperative high-field magnetic resonance imaging in transsphenoidal surgery of hormonally inactive pituitary macroadenomas. Neurosurgery. 2006;59(1):105\u2013114."},{"issue":"2","key":"b28","series-title":"Eur J Radiol","first-page":"299","article-title":"Imaging of the optic nerve","volume":"74","author":"Becker M","year":"2010","unstructured":"Becker M, Masterson K, Delavelle J, Viallon M, Vargas MI, Becker CD. Imaging of the optic nerve. Eur J Radiol. 2010;74(2):299\u2013313."},{"issue":"3","key":"b29","series-title":"Clin Radiol","first-page":"156","article-title":"A comparison of CT and MRI in the assessment of the pituitary and parasellar region","volume":"43","author":"Guy RL","year":"1991","unstructured":"Guy RL, Benn JJ, Ayers AB,  A comparison of CT and MRI in the assessment of the pituitary and parasellar region. Clin Radiol. 1991;43(3):156\u2013161."},{"issue":"7","key":"b30","series-title":"J Magn Reson Imaging","first-page":"e65","article-title":"Accessible magnetic resonance imaging: a review","volume":"49","author":"Geethanath S","year":"2019","unstructured":"Geethanath S, Vaughan JT Jr. Accessible magnetic resonance imaging: a review. J Magn Reson Imaging. 2019;49(7):e65\u2013e77."},{"issue":"1","key":"b31","series-title":"Sci Rep","first-page":"5690","article-title":"Development of a mobile low-field MRI scanner","volume":"12","author":"Deoni SCL","year":"2022","unstructured":"Deoni SCL, Medeiros P, Deoni AT,  Development of a mobile low-field MRI scanner. Sci Rep. 2022;12(1):5690."},{"issue":"5","key":"b32","series-title":"AJNR Am J Neuroradiol","first-page":"670","article-title":"Implementation of a low-field portable MRI scanner in a resource-constrained environment: our experience in Malawi","volume":"43","author":"Chetcuti K","year":"2022","unstructured":"Chetcuti K, Chilingulo C, Goyal MS,  Implementation of a low-field portable MRI scanner in a resource-constrained environment: our experience in Malawi. AJNR Am J Neuroradiol. 2022;43(5):670\u2013674."},{"key":"b33","series-title":"Advanced Analytics","article-title":"Handbook of Inter-Rater Reliability. The Definitive Guide to Measuring the Extent of Agreement Among Raters","author":"Gwet KL","year":"2014","unstructured":"Gwet KL. Handbook of Inter-Rater Reliability. The Definitive Guide to Measuring the Extent of Agreement Among Raters. 4th ed. Advanced Analytics; 2014."},{"issue":"3","key":"b34","series-title":"Radiology","first-page":"e220522","article-title":"Quantitative brain morphometry of portable low-field-strength MRI using super-resolution machine learning","volume":"306","author":"Iglesias JE","year":"2023","unstructured":"Iglesias JE, Schleicher R, Laguna S,  Quantitative brain morphometry of portable low-field-strength MRI using super-resolution machine learning. Radiology. 2023;306(3):e220522."}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/139\/6\/article-p1664.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/139\/6\/article-p1664.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/139\/6\/article-p1664.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T10:43:55Z","timestamp":1716029035000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/139\/6\/article-p1664.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,1]]},"references-count":34,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/2023.5.jns23174","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,1]]}}}