{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T02:47:34Z","timestamp":1794624454067,"version":"4.9.1"},"reference-count":45,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Pediatric achondroplasia is often associated with conditions requiring neurosurgical intervention, including CSF diversion and multilevel spinal decompression. However, there is a lack of clinical guidelines and reliable estimates of the benefits and risks of these interventions. This study aimed to summarize the literature on the neurosurgical management of pediatric achondroplasia patients in order to aid in determining optimal treatment and standardization of care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A systematic review of peer-reviewed studies with an objective diagnosis of achondroplasia, patient demographic information, and available data on neurosurgical interventions performed before 18 years of age for cervicomedullary compression, spinal stenosis, and hydrocephalus was performed. Study quality and risks of bias were assessed using standardized scores. Independent patient data on surgical indications, outcomes, reoperations, and complication risks were aggregated using means and percentages.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Of 204 records, 25 studies with 287 pediatric achondroplasia patients (mean age 25 \u00b1 36 months) treated for cervicomedullary compression (n = 153), spinal stenosis (n = 100), and obstructive hydrocephalus (n = 34) were evaluated. Symptomatic cervicomedullary compression occurred early in life (mean age 31 \u00b1 25 months), with apnea (48%), T2-weighted MRI cord signal (28%), myelopathy (27%), and delayed motor skills (15%) requiring foramen magnum decompression observed in 99% of patients, as well as cervical laminectomy in 65% of patients. Although 91% of treated patients had resolution of symptoms, 2% mortality, 9% reoperation, and 21% complication rates were reported. Spinal stenosis was treated in relatively older children (mean age 13 \u00b1 3 years) with laminectomy (23%), as well as with instrumented fusion (73%) for neurogenic claudication (59%), back pain (15%), and sciatica (8%). Although 95% of patients had symptom resolution after surgery, 17% reported complications and 18% required reoperation. Of the hydrocephalus patients (mean age 56 \u00b1 103 months), half were treated with endoscopic third ventriculostomy (ETV) and half had a shunt placed for progressive ventriculomegaly (66%), headaches (32%), and delayed cognitive development (4%). The shunted patients had a 3% mortality rate and an average of 1.5 shunt revisions per patient. None of the patients who underwent ETV as the primary procedure required a revision.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Neurosurgical intervention for pediatric achondroplasia conditions, including cervicomedullary compression, spinal stenosis, and hydrocephalus, is associated with high recovery rates and good outcomes. However, complications and reoperations are common. Further studies with follow-up into adulthood are needed to evaluate the long-term outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2023.6.peds23162","type":"journal-article","created":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T00:02:01Z","timestamp":1692403321000},"page":"597-606","source":"Crossref","is-referenced-by-count":15,"title":["Neurosurgical management of cervicomedullary compression, spinal stenosis, and hydrocephalus in pediatric achondroplasia: a systematic review"],"prefix":"10.3171","volume":"32","author":[{"given":"Oluwatoyin","family":"Akinnusotu","sequence":"first","affiliation":[{"name":"Meharry Medical College, Nashville, Tennessee; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert M.","family":"Isaacs","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Stone","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Bonfield","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"2","key":"b1","series-title":"Cell","first-page":"335","article-title":"Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia","volume":"78","author":"Shiang R","year":"1994","unstructured":"Shiang R, Thompson LM, Zhu YZ, . Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia. Cell. 1994;78(2):335\u2013342."},{"issue":"1","key":"b2","series-title":"Ann Neurol","first-page":"89","article-title":"Neurological basis of respiratory complications in achondroplasia","volume":"24","author":"Nelson FW","year":"1988","unstructured":"Nelson FW, Hecht JT, Horton WA, Butler IJ, Goldie WD, Miner M. Neurological basis of respiratory complications in achondroplasia. Ann Neurol. 1988;24(1):89\u201393."},{"issue":"1","key":"b3","series-title":"Horm Res Paediatr","first-page":"27","article-title":"Height outcome of recombinant human growth hormone treatment in achondroplasia children: a meta-analysis","volume":"86","author":"Miccoli M","year":"2016","unstructured":"Miccoli M, Bertelloni S, Massart F. Height outcome of recombinant human growth hormone treatment in achondroplasia children: a meta-analysis. Horm Res Paediatr. 2016;86(1):27\u201334."},{"key":"b4","series-title":"Human Achondroplasia: A Multidisciplinary Approach","first-page":"305","article-title":"Kyphosis and lumbar stenosis in achondroplasia","author":"Nelson MA","year":"1988","unstructured":"Nelson MA. Kyphosis and lumbar stenosis in achondroplasia. In: Human Achondroplasia: A Multidisciplinary Approach.Springer;1988:305-311."},{"issue":"3 suppl","key":"b5","series-title":"J Neurosurg","first-page":"166","article-title":"Cervicomedullary decompression for foramen magnum stenosis in achondroplasia","volume":"104","author":"Bagley CA","year":"2006","unstructured":"Bagley CA, Pindrik JA, Bookland MJ, Camara-Quintana JQ, Carson BS. Cervicomedullary decompression for foramen magnum stenosis in achondroplasia. J Neurosurg. 2006;104(3 suppl):166\u2013172."},{"issue":"5","key":"b6","series-title":"Int J Surg","first-page":"336","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"8","author":"Moher D","year":"2010","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg. 2010;8(5):336\u2013341."},{"key":"b7","series-title":"PROSPERO International Prospective Register of Systematic Reviews","article-title":"neurosurgical treatment outcomes of pediatric achondroplasia patients: a review of the literature","author":"Isaacs A","unstructured":"Isaacs A. neurosurgical treatment outcomes of pediatric achondroplasia patients: a review of the literature. CRD42023358077. PROSPERO International Prospective Register of Systematic Reviews.Accessed July 6, 2023.https:\/\/www.crd.york.ac.uk\/prospero\/#recordDetail"},{"key":"b8","series-title":"BMJ","first-page":"i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne JA","year":"2016","unstructured":"Sterne JA, Hernan MA, Reeves BC, . ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355:i4919."},{"key":"b9","series-title":"BMJ","first-page":"g5630","article-title":"A GRADE Working Group approach for rating the quality of treatment effect estimates from network meta-analysis","volume":"349","author":"Puhan MA","year":"2014","unstructured":"Puhan MA, Schunemann HJ, Murad MH, . A GRADE Working Group approach for rating the quality of treatment effect estimates from network meta-analysis. BMJ. 2014;349:g5630."},{"key":"b10","series-title":"R Foundation for Statistical Computing;","article-title":"R: A Language and Environment for Statistical Computing. Version 3.5.0","author":"R Development Core Team","year":"2018","unstructured":"R Development Core Team. R: A Language and Environment for Statistical Computing. Version 3.5.0. R Foundation for Statistical Computing; 2018."},{"issue":"11","key":"b11","series-title":"Eur Spine J","first-page":"2602","article-title":"The natural history of thoracolumbar kyphosis in achondroplasia","volume":"28","author":"Ahmed M","year":"2019","unstructured":"Ahmed M, El-Makhy M, Grevitt M. The natural history of thoracolumbar kyphosis in achondroplasia. Eur Spine J. 2019;28(11):2602\u20132607."},{"issue":"18","key":"b12","series-title":"Spine (Phila Pa 1976)","first-page":"2075","article-title":"Spinal arthrodesis with instrumentation for thoracolumbar kyphosis in pediatric achondroplasia","volume":"29","author":"Ain MC","year":"2004","unstructured":"Ain MC, Browne JA. Spinal arthrodesis with instrumentation for thoracolumbar kyphosis in pediatric achondroplasia. Spine (Phila Pa 1976).2004;29(18):2075\u20132080."},{"issue":"2","key":"b13","series-title":"Spine (Phila Pa 1976)","first-page":"197","article-title":"Postlaminectomy kyphosis in the skeletally immature achondroplast","volume":"31","author":"Ain MC","year":"2006","unstructured":"Ain MC, Shirley ED, Pirouzmanesh A, Hariri A, Carson BS. Postlaminectomy kyphosis in the skeletally immature achondroplast. Spine (Phila Pa 1976).2006;31(2):197\u2013201."},{"issue":"12","key":"b14","series-title":"Neurol Med Chir (Tokyo)","first-page":"902","article-title":"Intraoperative computed tomography for cervicomedullary decompression of foramen magnum stenosis in achondroplasia: two case reports","volume":"53","author":"Arishima H","year":"2013","unstructured":"Arishima H, Tsunetoshi K, Kodera T, Kitai R, Takeuchi H, Kikuta K. Intraoperative computed tomography for cervicomedullary decompression of foramen magnum stenosis in achondroplasia: two case reports. Neurol Med Chir (Tokyo). 2013;53(12):902\u2013906."},{"issue":"3","key":"b15","series-title":"J Neurosurg","first-page":"375","article-title":"Craniocervical decompression for cervicomedullary compression in pediatric patients with achondroplasia","volume":"73","author":"Aryanpur J","year":"1990","unstructured":"Aryanpur J, Hurko O, Francomano C, Wang H, Carson B. Craniocervical decompression for cervicomedullary compression in pediatric patients with achondroplasia. J Neurosurg. 1990;73(3):375\u2013382."},{"issue":"2 suppl","key":"b16","series-title":"J Neurosurg","first-page":"152","article-title":"Acute neurological deficit after minor trauma in an infant with achondroplasia and cervicomedullary compression. Case report and review of the literature","volume":"107","author":"Benglis DM","year":"2007","unstructured":"Benglis DM, Sandberg DI. Acute neurological deficit after minor trauma in an infant with achondroplasia and cervicomedullary compression. Case report and review of the literature. J Neurosurg. 2007;107(2 suppl):152\u2013155."},{"issue":"8","key":"b17","series-title":"J Pediatr Orthop","first-page":"780","article-title":"Spinal decompression in achondroplastic patients using high-speed drill versus ultrasonic bone curette: technical note and outcomes in 30 cases","volume":"34","author":"Bydon M","year":"2014","unstructured":"Bydon M, Macki M, Xu R, Ain MC, Ahn ES, Jallo GI. Spinal decompression in achondroplastic patients using high-speed drill versus ultrasonic bone curette: technical note and outcomes in 30 cases. J Pediatr Orthop. 2014;34(8):780\u2013786."},{"issue":"2","key":"b18","series-title":"Arch Dis Child","first-page":"180","article-title":"Achondroplasia Foramen Magnum Score: screening infants for stenosis","volume":"106","author":"Cheung MS","year":"2021","unstructured":"Cheung MS, Irving M, Cocca A, . Achondroplasia Foramen Magnum Score: screening infants for stenosis. Arch Dis Child. 2021;106(2):180\u2013184."},{"issue":"6 suppl","key":"b19","series-title":"Report of four cases. J Neurosurg","first-page":"504","article-title":"Dynamic cervicomedullary cord compression and alterations in cerebrospinal fluid dynamics in children with achondroplasia","volume":"107","author":"Danielpour M","year":"2007","unstructured":"Danielpour M, Wilcox WR, Alanay Y, Pressman BD, Rimoin DL. Dynamic cervicomedullary cord compression and alterations in cerebrospinal fluid dynamics in children with achondroplasia. Report of four cases. J Neurosurg. 2007;107(6 suppl):504\u2013507."},{"issue":"3 suppl","key":"b20","series-title":"J Neurosurg","first-page":"260","article-title":"The role of endoscopic third ventriculostomy in the treatment of triventricular hydrocephalus seen in children with achondroplasia","volume":"103","author":"Etus V","year":"2005","unstructured":"Etus V, Ceylan S. The role of endoscopic third ventriculostomy in the treatment of triventricular hydrocephalus seen in children with achondroplasia. J Neurosurg. 2005;103(3 suppl):260\u2013265."},{"issue":"3","key":"b21","series-title":"J Pediatr","first-page":"398","article-title":"Apnea as the sole manifestation of cord compression in achondroplasia","volume":"104","author":"Fremion AS","year":"1984","unstructured":"Fremion AS, Garg BP, Kalsbeck J. Apnea as the sole manifestation of cord compression in achondroplasia. J Pediatr. 1984;104(3):398\u2013401."},{"issue":"3","key":"b22","series-title":"J Neurosurg Pediatr","first-page":"268","article-title":"Hydrocephalus in achondroplasia: efficacy of endoscopic third ventriculostomy","volume":"29","author":"Kim J","year":"2022","unstructured":"Kim J, Patel VJ, El Ahmadieh TY, Olson DM, Swift DM. Hydrocephalus in achondroplasia: efficacy of endoscopic third ventriculostomy. 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Neurol Med Chir (Tokyo). 2010;50(12):1116\u20131118."},{"issue":"1","key":"b25","series-title":"J Neurosurg","first-page":"126","article-title":"Foramen magnum decompression in an infant with homozygous achondroplasia. Case report","volume":"70","author":"Moskowitz N","year":"1989","unstructured":"Moskowitz N, Carson B, Kopits S, Levitt R, Hart G. Foramen magnum decompression in an infant with homozygous achondroplasia. Case report. J Neurosurg. 1989;70(1):126\u2013128."},{"issue":"11","key":"b26","series-title":"Am J Med Genet A","first-page":"2540","article-title":"Natural history of achondroplasia: a retrospective review of longitudinal clinical data","volume":"182","author":"Okenfuss E","year":"2020","unstructured":"Okenfuss E, Moghaddam B, Avins AL. Natural history of achondroplasia: a retrospective review of longitudinal clinical data. Am J Med Genet A. 2020;182(11):2540\u20132551."},{"issue":"4","key":"b27","series-title":"J Pediatr","first-page":"522","article-title":"Cervicomedullary compression in young patients with achondroplasia: value of comprehensive neurologic and respiratory evaluation","volume":"110","author":"Reid CS","year":"1987","unstructured":"Reid CS, Pyeritz RE, Kopits SE, . Cervicomedullary compression in young patients with achondroplasia: value of comprehensive neurologic and respiratory evaluation. J Pediatr. 1987;110(4):522\u2013530."},{"issue":"8","key":"b28","series-title":"Childs Nerv Syst","first-page":"1295","article-title":"Pathogenesis of hydrocephalus in achondroplastic dwarfs: a review and presentation of a case followed for 22 years","volume":"35","author":"Rekate HL","year":"2019","unstructured":"Rekate HL. Pathogenesis of hydrocephalus in achondroplastic dwarfs: a review and presentation of a case followed for 22 years. Childs Nerv Syst. 2019;35(8):1295\u20131301."},{"issue":"11","key":"b29","series-title":"Childs Nerv Syst","first-page":"2275","article-title":"Polysomnography as an indicator for cervicomedullary decompression to treat foramen magnum stenosis in achondroplasia","volume":"34","author":"Sano M","year":"2018","unstructured":"Sano M, Takahashi N, Nagasaki K, Oishi M, Yoshimura J, Fujii Y. Polysomnography as an indicator for cervicomedullary decompression to treat foramen magnum stenosis in achondroplasia. Childs Nerv Syst. 2018;34(11):2275\u20132281."},{"issue":"5 suppl","key":"b30","series-title":"J Neurosurg","first-page":"372","article-title":"Spinal stenosis surgery in pediatric patients with achondroplasia","volume":"106","author":"Sciubba DM","year":"2007","unstructured":"Sciubba DM, Noggle JC, Marupudi NI, . Spinal stenosis surgery in pediatric patients with achondroplasia. J Neurosurg. 2007;106(5 suppl):372\u2013378."},{"issue":"12","key":"b31","series-title":"Childs Nerv Syst","first-page":"3907","article-title":"Endoscopic third ventriculostomy for hydrocephalus in a patient with achondroplasia: a case report and literature review","volume":"37","author":"Shoda K","year":"2021","unstructured":"Shoda K, Ohe N, Sasai H, Miyai M, Ohnishi H, Iwama T. Endoscopic third ventriculostomy for hydrocephalus in a patient with achondroplasia: a case report and literature review. Childs Nerv Syst. 2021;37(12):3907\u20133911."},{"issue":"1","key":"b32","series-title":"Am J Med Genet A","first-page":"182","article-title":"Craniocervical junction issues after infancy in achondroplasia","volume":"185","author":"Smid CJ","year":"2021","unstructured":"Smid CJ, Legare JM, Modaff P, Pauli RM. Craniocervical junction issues after infancy in achondroplasia. Am J Med Genet A. 2021;185(1):182\u2013189."},{"issue":"1","key":"b33","series-title":"J Neurosurg Pediatr","first-page":"73","article-title":"Endoscopic third ventriculostomy in hydrocephalus associated with achondroplasia","volume":"9","author":"Swift D","year":"2012","unstructured":"Swift D, Nagy L, Robertson B. Endoscopic third ventriculostomy in hydrocephalus associated with achondroplasia. J Neurosurg Pediatr. 2012;9(1):73\u201381."},{"issue":"2","key":"b34","series-title":"Radiology","first-page":"515","article-title":"Pediatric patients with achondroplasia: CT evaluation of the craniocervical junction","volume":"164","author":"Wang H","year":"1987","unstructured":"Wang H, Rosenbaum AE, Reid CS, Zinreich SJ, Pyeritz RE. Pediatric patients with achondroplasia: CT evaluation of the craniocervical junction. Radiology. 1987;164(2):515\u2013519."},{"issue":"4","key":"b35","series-title":"Childs Brain","first-page":"205","article-title":"Hydrocephalus and achondroplasia. A study of 25 observations","volume":"7","author":"Pierre-Kahn A","year":"1980","unstructured":"Pierre-Kahn A, Hirsch JF, Renier D, Metzger J, Maroteaux P. Hydrocephalus and achondroplasia. A study of 25 observations. Childs Brain. 1980;7(4):205\u2013219."},{"issue":"6","key":"b36","series-title":"Childs Nerv Syst","first-page":"345","article-title":"Hydrocephalus and chronically increased intracranial pressure in achondroplasia","volume":"13","author":"Erdin\u00e7ler P","year":"1997","unstructured":"Erdin\u00e7ler P, Dashti R, Kaynar MY, Canbaz B, Ciplak N, Kuday C. Hydrocephalus and chronically increased intracranial pressure in achondroplasia. Childs Nerv Syst. 1997;13(6):345\u2013348."},{"key":"b37","first-page":"1065","article-title":"Hydrocephalus in achondroplasia and venous hypertension","author":"Ramachandran S","year":"2019","unstructured":"Ramachandran S, Steinbok P. Hydrocephalus in achondroplasia and venous hypertension. In: Cinalli G, \u00d6zek MM, Sainte-Rose C, eds. 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