{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:02:50Z","timestamp":1787025770573,"version":"build-2736575974"},"reference-count":26,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,1]]},"abstract":"<jats:p>Magnetic resonance\u2013guided focused ultrasound (MRgFUS) is one of the newest surgical treatments for essential tremor (ET). During this procedure, a lesion is created within the thalamus to mitigate tremor. Targeting is done using a combination of stereotaxy, MR tractography, and sublesional heating, with tremor assessed during the procedure to gauge therapeutic effectiveness. Currently, tremor assessments are done qualitatively, but this approach requires the tremor change to be above a subjective threshold and provides no objective record of surgical tremor progression. Here, the authors present and demonstrate an MR-compatible accelerometer with custom MATLAB analysis code and graphical user interface to record, visualize, and quantify tremor in near real-time. Results can be exported and saved for future review. This method was used in 20 surgeries, with patients experiencing a 50.7% (95% CI \u221264.1% to \u221237.3%) improvement in the treated limb per the Clinical Rating Scale for Tremor. This method does not interrupt the surgery and is quantitative. As research on optimizing MRgFUS treatment for ET continues\u2014for example, the refinement of targeting during sublesional sonications\u2014such quantifying and recording of tremor changes will provide rapid and objective feedback.<\/jats:p>","DOI":"10.3171\/2024.1.jns231830","type":"journal-article","created":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T21:22:50Z","timestamp":1713561770000},"page":"1088-1095","source":"Crossref","is-referenced-by-count":3,"title":["An intraoperative accelerometry and real-time analysis tool for magnetic resonance\u2013guided focused ultrasound thalamotomy"],"prefix":"10.3171","volume":"141","author":[{"given":"Catherine A.","family":"Swytink-Binnema","sequence":"first","affiliation":[{"name":"Departments of Clinical Neurosciences and"},{"name":"Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Coreas","sequence":"additional","affiliation":[{"name":"Departments of Clinical Neurosciences and"},{"name":"Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Pichardo","sequence":"additional","affiliation":[{"name":"Departments of Clinical Neurosciences and"},{"name":"Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada; and"},{"name":"Hotchkiss Brain Institute, University of Calgary, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Bruce","family":"Pike","sequence":"additional","affiliation":[{"name":"Departments of Clinical Neurosciences and"},{"name":"Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada; and"},{"name":"Hotchkiss Brain Institute, University of Calgary, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zelma H. T.","family":"Kiss","sequence":"additional","affiliation":[{"name":"Departments of Clinical Neurosciences and"},{"name":"Hotchkiss Brain Institute, University of Calgary, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"5","key":"b1","series-title":"Mov Disord","first-page":"534","article-title":"How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor","volume":"25","author":"Louis ED","year":"2010","unstructured":"Louis ED, Ferreira JJ. How common is the most common adult movement disorder? 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