{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:01:30Z","timestamp":1782864090687,"version":"3.54.5"},"reference-count":16,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"Surgically remediable epilepsy of the eloquent brain poses the added challenge of preserving function while curing disease. Long-standing epileptogenic lesions have tenacious seizure networks and significant functional reorganizations. Large multilobar lesions may involve multiple functional areas, thereby challenging the limits of functional brain mapping. In this video, the authors describe a dominant hemisphere fronto-parieto-temporo-occipital malformation of cortical development, involving the language, sensorimotor, and visual cortices, placing multiple eloquent cortical and subcortical regions at risk. They illustrate the technique of hexamodal mapping\/monitoring involving the language sensorimotor areas, optic radiation, auditory pathway, and ictal irritative zone for a multilobar resection, with good seizure outcome and function preservation.<\/jats:p>\n \n The video can be found here:\n https:\/\/stream.cadmore.media\/r10.3171\/2024.10.FOCVID24111<\/jats:ext-link>\n <\/jats:p>","DOI":"10.3171\/2024.10.focvid24111","type":"journal-article","created":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T01:13:49Z","timestamp":1735694029000},"page":"V4","source":"Crossref","is-referenced-by-count":0,"title":["Hexamodal awake brain mapping (language, sensorimotor, ictal, visual, auditory) for multilobar resection in a dominant hemisphere parieto-fronto-temporo-occipital cortical malformation with drug-resistant epilepsy"],"prefix":"10.3171","volume":"12","author":[{"given":"Lokesh V.","family":"Dasarathan","sequence":"first","affiliation":[{"name":"Department of Neurosurgery,"},{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George C.","family":"Vilanilam","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery,"},{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankush R.","family":"Parate","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Revikrishnan","family":"Sreekumar","sequence":"additional","affiliation":[{"name":"Department of Neuroanaesthesia, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita","family":"Vimala","sequence":"additional","affiliation":[{"name":"Department of Neuroanaesthesia, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manikandan","family":"Sethuraman","sequence":"additional","affiliation":[{"name":"Department of Neuroanaesthesia, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramshekhar N.","family":"Menon","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashalatha","family":"Radhakrishnan","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karamala Y.","family":"Manisha","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nandana","family":"Jayakumari","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajalakshmi","family":"Poyuran","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nandini S.","family":"Nair","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anees","family":"Chembakodan","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manju P.","family":"Mohan","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vipina V.","family":"Padmakumari","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayana L.","family":"Nair","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Vashishta","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandrasekharan","family":"Kesavadas","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bejoy","family":"Thomas","sequence":"additional","affiliation":[{"name":"R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishnakumar","family":"Kesavapisharady","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"5","key":"b1","series-title":"Neurosurgery","first-page":"919","article-title":"New philosophy, clinical pearls, and methods for intraoperative cognition mapping and monitoring \"\u00e0 la carte\" in brain tumor patients","volume":"88","author":"Duffau H","year":"2021","unstructured":"Duffau H. New philosophy, clinical pearls, and methods for intraoperative cognition mapping and monitoring \"\u00e0 la carte\" in brain tumor patients. Neurosurgery. 2021;88(5):919\u2013930."},{"issue":"6","key":"b2","series-title":"Neurosurg Focus","first-page":"E4","article-title":"Neurosurgery for eloquent lesions in children: state-of-the-art rationale and technical implications of perioperative neurophysiology","volume":"53","author":"Krieg SM","year":"2022","unstructured":"Krieg SM, Bernhard D, Ille S, Neurosurgery for eloquent lesions in children: state-of-the-art rationale and technical implications of perioperative neurophysiology. Neurosurg Focus. 2022;53(6):E4."},{"issue":"3","key":"b3","series-title":"J Neurosurg Sci","first-page":"113","article-title":"Indications and limits of intraoperative cortico-subcortical mapping in brain tumor surgery: an analysis of 101 consecutive cases","volume":"51","author":"Signorelli F","year":"2007","unstructured":"Signorelli F, Ruggeri F, Iofrida G, Indications and limits of intraoperative cortico-subcortical mapping in brain tumor surgery: an analysis of 101 consecutive cases. 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Neurosurg Focus. 2022;53(6):E4."},{"issue":"3","key":"b3","series-title":"J Neurosurg Sci","first-page":"113","article-title":"Indications and limits of intraoperative cortico-subcortical mapping in brain tumor surgery: an analysis of 101 consecutive cases","volume":"51","author":"Signorelli F","year":"2007","unstructured":"Signorelli F, Ruggeri F, Iofrida G, Indications and limits of intraoperative cortico-subcortical mapping in brain tumor surgery: an analysis of 101 consecutive cases. 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