{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T15:29:45Z","timestamp":1772724585870,"version":"3.50.1"},"reference-count":50,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Although anterior temporal lobectomy (ATL) has the highest efficacy for temporal lobe epilepsy (TLE), there is currently a trend toward performing minimally invasive surgery (MIS) for TLE. However, the MIS methods, such as laser thermocoagulation, have been used at the expense of efficacy. Functional ATL (FATL), which involves functional disconnection instead of anatomical resection and was designed by the authors, resolves this problem. This study aimed to evaluate seizure outcomes of FATL as an MIS for TLE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A consecutive case series of FATLs for ATL was conducted between 2020 and 2022. FATL was scheduled after standard presurgical evaluations of TLE and applied the same criteria as standard ATL. Seizure outcomes were categorized by Engel classifications, with at least 2 years of follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Forty-nine patients with TLE who underwent FATL were included in the case series. The mean follow-up duration was 31.9 (range 24\u201342) months. Freedom from disabling seizures (Engel class I) occurred in 36 patients (73.5%) and significant improvement (Engel class I\u2013II) occurred in 44 (89.8%) after surgery. The rate of complete freedom from all seizures (Engel class Ia) was 77.6% at 1 year after surgery and 69.4% at 2 years. No deaths or permanent morbidities after FATL were recorded. The complication rate was 2.0%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>FATL incorporates a change from anatomical resection to functional disconnection without brain shift. As a keyhole surgery, the FATL incision is barely visible, with a better cosmetic appearance than ATL. FATL has the MIS quality as well as excellent seizure outcomes similar to those of ATL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2024.10.jns241152","type":"journal-article","created":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T09:06:38Z","timestamp":1742634398000},"page":"755-764","source":"Crossref","is-referenced-by-count":2,"title":["Functional anterior temporal lobectomy for temporal lobe epilepsy: from anatomical resection to functional disconnection"],"prefix":"10.3171","volume":"143","author":[{"given":"Yong","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutao","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"},{"name":"Center of Brain Science, The First Affiliated Hospital of Xi\u2019an Jiaotong University; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"},{"name":"Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi\u2019an Jiaotong University, Xi\u2019an, Shaanxi, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huanfa","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anqing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"},{"name":"Center of Brain Science, The First Affiliated Hospital of Xi\u2019an Jiaotong University; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haohao","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"},{"name":"Center of Brain Science, The First Affiliated Hospital of Xi\u2019an Jiaotong University; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaobo","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"},{"name":"Center of Brain Science, The First Affiliated Hospital of Xi\u2019an Jiaotong University; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changwang","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Clinical Research Center for Refractory Epilepsy of Shaanxi Province, and"},{"name":"Center of Brain Science, The First Affiliated Hospital of Xi\u2019an Jiaotong University; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Epilepsy Res Treat","first-page":"630853","article-title":"A review of the epidemiology of temporal lobe epilepsy","volume":"2012","author":"T\u00e9llez-Zenteno JF","year":"2012","unstructured":"T\u00e9llez-Zenteno JF, Hern\u00e1ndez-Ronquillo L. A review of the epidemiology of temporal lobe epilepsy. Epilepsy Res Treat. 2012;2012:630853."},{"issue":"3","key":"b2","series-title":"Lancet Neurol","first-page":"173","article-title":"Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy","volume":"1","author":"Pitk\u00e4nen A","year":"2002","unstructured":"Pitk\u00e4nen A, Sutula TP. Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy. Lancet Neurol. 2002;1(3):173\u2013181."},{"issue":"2","key":"b3","series-title":"Epileptic Disord","first-page":"137","article-title":"How many adults with temporal epilepsy have a mild course and do not require epilepsy surgery?","volume":"18","author":"Hern\u00e1ndez-Ronquillo L","year":"2016","unstructured":"Hern\u00e1ndez-Ronquillo L, Buckley S, Ladino LD,  How many adults with temporal epilepsy have a mild course and do not require epilepsy surgery?. Epileptic Disord. 2016;18(2):137-147."},{"issue":"6","key":"b4","series-title":"Cochrane Database Syst Rev","first-page":"CD010541","article-title":"Surgery for epilepsy","volume":"6","author":"West S","year":"2019","unstructured":"West S, Nevitt SJ, Cotton J,  Surgery for epilepsy. Cochrane Database Syst Rev. 2019;6(6):CD010541."},{"issue":"5","key":"b5","series-title":"N Engl J Med","first-page":"311","article-title":"A randomized, controlled trial of surgery for temporal-lobe epilepsy","volume":"345","author":"Wiebe S","year":"2001","unstructured":"Wiebe S, Blume WT, Girvin JP, Eliasziw M. A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med. 2001;345(5):311-318."},{"issue":"9","key":"b6","series-title":"JAMA","first-page":"922","article-title":"Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial","volume":"307","author":"Engel J Jr","year":"2012","unstructured":"Engel J Jr, McDermott MP, Wiebe S,  Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. JAMA. 2012;307(9):922-930."},{"issue":"10","key":"b7","series-title":"Neurology","first-page":"e1404","article-title":"Cost-effectiveness of surgery for drug-resistant temporal lobe epilepsy in the US","volume":"95","author":"Sheikh SR","year":"2020","unstructured":"Sheikh SR, Kattan MW, Steinmetz M, Singer ME, Udeh BL, Jehi L. Cost-effectiveness of surgery for drug-resistant temporal lobe epilepsy in the US. Neurology. 2020;95(10):e1404-e1416."},{"issue":"4","key":"b8","series-title":"AMA Arch Neurol Psychiatry","first-page":"491","article-title":"Surgical therapy of temporal lobe seizures","volume":"64","author":"Penfield W","year":"1950","unstructured":"Penfield W, Flanigin H. Surgical therapy of temporal lobe seizures. AMA Arch Neurol Psychiatry. 1950;64(4):491-500."},{"issue":"2","key":"b9","series-title":"Stereotact Funct Neurosurg","first-page":"69","article-title":"Complications after anterior temporal lobectomy for medically intractable epilepsy: a systematic review and meta-analysis","volume":"97","author":"Brotis AG","year":"2019","unstructured":"Brotis AG, Giannis T, Kapsalaki E, Dardiotis E, Fountas KN. Complications after anterior temporal lobectomy for medically intractable epilepsy: a systematic review and meta-analysis. Stereotact Funct Neurosurg. 2019;97(2):69-82."},{"key":"b10","series-title":"Front Neurol","first-page":"722478","article-title":"Severity grading, risk factors and prediction model of complications after epilepsy surgery: a large-scale and retrospective study","volume":"12","author":"Liu Y","year":"2021","unstructured":"Liu Y, Wu H, Li H,  Severity grading, risk factors and prediction model of complications after epilepsy surgery: a large-scale and retrospective study. Front Neurol. 2021;12:722478."},{"issue":"Pt A","key":"b11","series-title":"Epilepsy Behav","first-page":"57","article-title":"History of surgery for temporal lobe epilepsy","volume":"70","author":"Asadi-Pooya AA","year":"2017","unstructured":"Asadi-Pooya AA, Rostami C. History of surgery for temporal lobe epilepsy. Epilepsy Behav. 2017;70(Pt A):57-60."},{"issue":"11","key":"b12","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1138","article-title":"Systematic review and network meta-analysis of resective surgery for mesial temporal lobe epilepsy","volume":"89","author":"Jain P","year":"2018","unstructured":"Jain P, Tomlinson G, Snead C, Sander B, Widjaja E. Systematic review and network meta-analysis of resective surgery for mesial temporal lobe epilepsy. J Neurol Neurosurg Psychiatry. 2018;89(11):1138-1144."},{"issue":"5","key":"b13","series-title":"J Neurosurg","first-page":"1089","article-title":"Selective amygdalohippocampectomy versus anterior temporal lobectomy in the management of mesial temporal lobe epilepsy: a meta-analysis of comparative studies","volume":"119","author":"Hu WH","year":"2013","unstructured":"Hu WH, Zhang C, Zhang K, Meng FG, Chen N, Zhang JG. Selective amygdalohippocampectomy versus anterior temporal lobectomy in the management of mesial temporal lobe epilepsy: a meta-analysis of comparative studies. J Neurosurg. 2013;119(5):1089-1097."},{"key":"b14","series-title":"Front Neurol","first-page":"777845","article-title":"Resective, ablative and radiosurgical interventions for drug resistant mesial temporal lobe epilepsy: a systematic review and meta-analysis of outcomes","volume":"12","author":"Marathe K","year":"2021","unstructured":"Marathe K, Alim-Marvasti A, Dahele K,  Resective, ablative and radiosurgical interventions for drug resistant mesial temporal lobe epilepsy: a systematic review and meta-analysis of outcomes. Front Neurol. 2021;12:777845."},{"issue":"1","key":"b15","series-title":"Neurosurg Rev","first-page":"89","article-title":"Multivariate analysis of seizure outcomes after resective surgery for focal epilepsy: a single-center study on 833 patients","volume":"46","author":"Meng Q","year":"2023","unstructured":"Meng Q, Liu Y, Ren Y,  Multivariate analysis of seizure outcomes after resective surgery for focal epilepsy: a single-center study on 833 patients. Neurosurg Rev. 2023;46(1):89."},{"issue":"1","key":"b16","series-title":"Oper Neurosurg (Hagerstown)","first-page":"111","article-title":"Functional anterior temporal lobectomy for temporal lobe epilepsy: a novel, alternative, and less invasive therapy","volume":"24","author":"Liu Y","year":"2023","unstructured":"Liu Y, Ren Y, Meng Q,  Functional anterior temporal lobectomy for temporal lobe epilepsy: a novel, alternative, and less invasive therapy. Oper Neurosurg (Hagerstown). 2023;24(1):111\u2013118."},{"issue":"Pt 9","key":"b17","series-title":"Brain","first-page":"2018","article-title":"Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence","volume":"127","author":"McIntosh AM","year":"2004","unstructured":"McIntosh AM, Kalnins RM, Mitchell LA, Fabinyi GC, Briellmann RS, Berkovic SF. Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence. Brain. 2004;127(Pt 9):2018-2030."},{"key":"b18","series-title":"Epilepsy Behav","first-page":"24","article-title":"Minimally invasive surgical approaches for temporal lobe epilepsy","volume":"47","author":"Chang EF","year":"2015","unstructured":"Chang EF, Englot DJ, Vadera S. Minimally invasive surgical approaches for temporal lobe epilepsy. Epilepsy Behav. 2015;47:24\u201333."},{"key":"b19","series-title":"Front Neurol","first-page":"833293","article-title":"Long-term outcome of temporal lobe epilepsy surgery in 621 patients with hippocampal sclerosis: clinical and surgical prognostic factors","volume":"13","author":"Pereira Dalio MTR","year":"2022","unstructured":"Pereira Dalio MTR, Velasco TR, Feitosa IDF,  Long-term outcome of temporal lobe epilepsy surgery in 621 patients with hippocampal sclerosis: clinical and surgical prognostic factors. Front Neurol. 2022;13:833293."},{"issue":"9","key":"b20","series-title":"Healthcare (Basel)","first-page":"1156","article-title":"Long-term neuropsychological outcomes following temporal lobe epilepsy surgery: an update of the literature","volume":"9","author":"Alexandratou I","year":"2021","unstructured":"Alexandratou I, Patrikelis P, Messinis L,  Long-term neuropsychological outcomes following temporal lobe epilepsy surgery: an update of the literature. Healthcare (Basel). 2021;9(9):1156."},{"issue":"6","key":"b21","series-title":"Neurosurgery","first-page":"1531","article-title":"Temporal lobotomy in the surgical management of epilepsy: technical report","volume":"54","author":"Smith JR","year":"2004","unstructured":"Smith JR, VanderGriff A, Fountas K. Temporal lobotomy in the surgical management of epilepsy: technical report. Neurosurgery. 2004;54(6):1531-1536."},{"issue":"3","key":"b22","series-title":"Article in French. Neurochirurgie","first-page":"297","article-title":"Temporal disconnection as an alternative treatment for intractable temporal lobe epilepsy: techniques, complications and results","volume":"54","author":"Chabard\u00e8s S","year":"2008","unstructured":"Chabard\u00e8s S, Minotti L, Hamelin S,  Temporal disconnection as an alternative treatment for intractable temporal lobe epilepsy: techniques, complications and results. Article in French. Neurochirurgie. 2008;54(3):297-302."},{"issue":"12","key":"b23","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1378","article-title":"Long-term outcome of surgical disconnection of the epileptic zone as an alternative to resection for nonlesional mesial temporal epilepsy","volume":"84","author":"Massager N","year":"2013","unstructured":"Massager N, Tugendhaft P, Depondt C,  Long-term outcome of surgical disconnection of the epileptic zone as an alternative to resection for nonlesional mesial temporal epilepsy. J Neurol Neurosurg Psychiatry. 2013;84(12):1378-1383."},{"issue":"2","key":"b24","series-title":"Neurol Res","first-page":"164","article-title":"Comparison of seizure outcomes and safety between anterior temporal lobotomy and lobectomy in patients with temporal lobe epilepsy","volume":"42","author":"Yang X","year":"2020","unstructured":"Yang X, Liu Q, Yang Q,  Comparison of seizure outcomes and safety between anterior temporal lobotomy and lobectomy in patients with temporal lobe epilepsy. Neurol Res. 2020;42(2):164-169."},{"key":"b25","series-title":"Front Neurol","first-page":"580221","article-title":"Side of lesions predicts surgical outcomes in patients with drug-resistant temporal lobe epilepsy secondary to focal cortical dysplasia type IIIa","volume":"11","author":"He X","year":"2020","unstructured":"He X, Liu D, Yang Z, Zhang J, Li S, Yang Z. Side of lesions predicts surgical outcomes in patients with drug-resistant temporal lobe epilepsy secondary to focal cortical dysplasia type IIIa. Front Neurol. 2020;11:580221."},{"key":"b1","series-title":"Epilepsy Res Treat","first-page":"630853","article-title":"A review of the epidemiology of temporal lobe epilepsy","volume":"2012","author":"T\u00e9llez-Zenteno JF","year":"2012","unstructured":"T\u00e9llez-Zenteno JF, Hern\u00e1ndez-Ronquillo L. A review of the epidemiology of temporal lobe epilepsy. Epilepsy Res Treat. 2012;2012:630853."},{"issue":"3","key":"b2","series-title":"Lancet Neurol","first-page":"173","article-title":"Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy","volume":"1","author":"Pitk\u00e4nen A","year":"2002","unstructured":"Pitk\u00e4nen A, Sutula TP. Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy. Lancet Neurol. 2002;1(3):173\u2013181."},{"issue":"2","key":"b3","series-title":"Epileptic Disord","first-page":"137","article-title":"How many adults with temporal epilepsy have a mild course and do not require epilepsy surgery?","volume":"18","author":"Hern\u00e1ndez-Ronquillo L","year":"2016","unstructured":"Hern\u00e1ndez-Ronquillo L, Buckley S, Ladino LD,  How many adults with temporal epilepsy have a mild course and do not require epilepsy surgery?. Epileptic Disord. 2016;18(2):137-147."},{"issue":"6","key":"b4","series-title":"Cochrane Database Syst Rev","first-page":"CD010541","article-title":"Surgery for epilepsy","volume":"6","author":"West S","year":"2019","unstructured":"West S, Nevitt SJ, Cotton J,  Surgery for epilepsy. Cochrane Database Syst Rev. 2019;6(6):CD010541."},{"issue":"5","key":"b5","series-title":"N Engl J Med","first-page":"311","article-title":"A randomized, controlled trial of surgery for temporal-lobe epilepsy","volume":"345","author":"Wiebe S","year":"2001","unstructured":"Wiebe S, Blume WT, Girvin JP, Eliasziw M. A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med. 2001;345(5):311-318."},{"issue":"9","key":"b6","series-title":"JAMA","first-page":"922","article-title":"Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial","volume":"307","author":"Engel J Jr","year":"2012","unstructured":"Engel J Jr, McDermott MP, Wiebe S,  Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. JAMA. 2012;307(9):922-930."},{"issue":"10","key":"b7","series-title":"Neurology","first-page":"e1404","article-title":"Cost-effectiveness of surgery for drug-resistant temporal lobe epilepsy in the US","volume":"95","author":"Sheikh SR","year":"2020","unstructured":"Sheikh SR, Kattan MW, Steinmetz M, Singer ME, Udeh BL, Jehi L. Cost-effectiveness of surgery for drug-resistant temporal lobe epilepsy in the US. Neurology. 2020;95(10):e1404-e1416."},{"issue":"4","key":"b8","series-title":"AMA Arch Neurol Psychiatry","first-page":"491","article-title":"Surgical therapy of temporal lobe seizures","volume":"64","author":"Penfield W","year":"1950","unstructured":"Penfield W, Flanigin H. Surgical therapy of temporal lobe seizures. AMA Arch Neurol Psychiatry. 1950;64(4):491-500."},{"issue":"2","key":"b9","series-title":"Stereotact Funct Neurosurg","first-page":"69","article-title":"Complications after anterior temporal lobectomy for medically intractable epilepsy: a systematic review and meta-analysis","volume":"97","author":"Brotis AG","year":"2019","unstructured":"Brotis AG, Giannis T, Kapsalaki E, Dardiotis E, Fountas KN. Complications after anterior temporal lobectomy for medically intractable epilepsy: a systematic review and meta-analysis. Stereotact Funct Neurosurg. 2019;97(2):69-82."},{"key":"b10","series-title":"Front Neurol","first-page":"722478","article-title":"Severity grading, risk factors and prediction model of complications after epilepsy surgery: a large-scale and retrospective study","volume":"12","author":"Liu Y","year":"2021","unstructured":"Liu Y, Wu H, Li H,  Severity grading, risk factors and prediction model of complications after epilepsy surgery: a large-scale and retrospective study. Front Neurol. 2021;12:722478."},{"issue":"Pt A","key":"b11","series-title":"Epilepsy Behav","first-page":"57","article-title":"History of surgery for temporal lobe epilepsy","volume":"70","author":"Asadi-Pooya AA","year":"2017","unstructured":"Asadi-Pooya AA, Rostami C. History of surgery for temporal lobe epilepsy. Epilepsy Behav. 2017;70(Pt A):57-60."},{"issue":"11","key":"b12","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1138","article-title":"Systematic review and network meta-analysis of resective surgery for mesial temporal lobe epilepsy","volume":"89","author":"Jain P","year":"2018","unstructured":"Jain P, Tomlinson G, Snead C, Sander B, Widjaja E. Systematic review and network meta-analysis of resective surgery for mesial temporal lobe epilepsy. J Neurol Neurosurg Psychiatry. 2018;89(11):1138-1144."},{"issue":"5","key":"b13","series-title":"J Neurosurg","first-page":"1089","article-title":"Selective amygdalohippocampectomy versus anterior temporal lobectomy in the management of mesial temporal lobe epilepsy: a meta-analysis of comparative studies","volume":"119","author":"Hu WH","year":"2013","unstructured":"Hu WH, Zhang C, Zhang K, Meng FG, Chen N, Zhang JG. Selective amygdalohippocampectomy versus anterior temporal lobectomy in the management of mesial temporal lobe epilepsy: a meta-analysis of comparative studies. J Neurosurg. 2013;119(5):1089-1097."},{"key":"b14","series-title":"Front Neurol","first-page":"777845","article-title":"Resective, ablative and radiosurgical interventions for drug resistant mesial temporal lobe epilepsy: a systematic review and meta-analysis of outcomes","volume":"12","author":"Marathe K","year":"2021","unstructured":"Marathe K, Alim-Marvasti A, Dahele K,  Resective, ablative and radiosurgical interventions for drug resistant mesial temporal lobe epilepsy: a systematic review and meta-analysis of outcomes. Front Neurol. 2021;12:777845."},{"issue":"1","key":"b15","series-title":"Neurosurg Rev","first-page":"89","article-title":"Multivariate analysis of seizure outcomes after resective surgery for focal epilepsy: a single-center study on 833 patients","volume":"46","author":"Meng Q","year":"2023","unstructured":"Meng Q, Liu Y, Ren Y,  Multivariate analysis of seizure outcomes after resective surgery for focal epilepsy: a single-center study on 833 patients. Neurosurg Rev. 2023;46(1):89."},{"issue":"1","key":"b16","series-title":"Oper Neurosurg (Hagerstown)","first-page":"111","article-title":"Functional anterior temporal lobectomy for temporal lobe epilepsy: a novel, alternative, and less invasive therapy","volume":"24","author":"Liu Y","year":"2023","unstructured":"Liu Y, Ren Y, Meng Q,  Functional anterior temporal lobectomy for temporal lobe epilepsy: a novel, alternative, and less invasive therapy. Oper Neurosurg (Hagerstown). 2023;24(1):111\u2013118."},{"issue":"Pt 9","key":"b17","series-title":"Brain","first-page":"2018","article-title":"Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence","volume":"127","author":"McIntosh AM","year":"2004","unstructured":"McIntosh AM, Kalnins RM, Mitchell LA, Fabinyi GC, Briellmann RS, Berkovic SF. Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence. Brain. 2004;127(Pt 9):2018-2030."},{"key":"b18","series-title":"Epilepsy Behav","first-page":"24","article-title":"Minimally invasive surgical approaches for temporal lobe epilepsy","volume":"47","author":"Chang EF","year":"2015","unstructured":"Chang EF, Englot DJ, Vadera S. Minimally invasive surgical approaches for temporal lobe epilepsy. Epilepsy Behav. 2015;47:24\u201333."},{"key":"b19","series-title":"Front Neurol","first-page":"833293","article-title":"Long-term outcome of temporal lobe epilepsy surgery in 621 patients with hippocampal sclerosis: clinical and surgical prognostic factors","volume":"13","author":"Pereira Dalio MTR","year":"2022","unstructured":"Pereira Dalio MTR, Velasco TR, Feitosa IDF,  Long-term outcome of temporal lobe epilepsy surgery in 621 patients with hippocampal sclerosis: clinical and surgical prognostic factors. Front Neurol. 2022;13:833293."},{"issue":"9","key":"b20","series-title":"Healthcare (Basel)","first-page":"1156","article-title":"Long-term neuropsychological outcomes following temporal lobe epilepsy surgery: an update of the literature","volume":"9","author":"Alexandratou I","year":"2021","unstructured":"Alexandratou I, Patrikelis P, Messinis L,  Long-term neuropsychological outcomes following temporal lobe epilepsy surgery: an update of the literature. Healthcare (Basel). 2021;9(9):1156."},{"issue":"6","key":"b21","series-title":"Neurosurgery","first-page":"1531","article-title":"Temporal lobotomy in the surgical management of epilepsy: technical report","volume":"54","author":"Smith JR","year":"2004","unstructured":"Smith JR, VanderGriff A, Fountas K. Temporal lobotomy in the surgical management of epilepsy: technical report. Neurosurgery. 2004;54(6):1531-1536."},{"issue":"3","key":"b22","series-title":"Article in French. Neurochirurgie","first-page":"297","article-title":"Temporal disconnection as an alternative treatment for intractable temporal lobe epilepsy: techniques, complications and results","volume":"54","author":"Chabard\u00e8s S","year":"2008","unstructured":"Chabard\u00e8s S, Minotti L, Hamelin S,  Temporal disconnection as an alternative treatment for intractable temporal lobe epilepsy: techniques, complications and results. Article in French. Neurochirurgie. 2008;54(3):297-302."},{"issue":"12","key":"b23","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1378","article-title":"Long-term outcome of surgical disconnection of the epileptic zone as an alternative to resection for nonlesional mesial temporal epilepsy","volume":"84","author":"Massager N","year":"2013","unstructured":"Massager N, Tugendhaft P, Depondt C,  Long-term outcome of surgical disconnection of the epileptic zone as an alternative to resection for nonlesional mesial temporal epilepsy. J Neurol Neurosurg Psychiatry. 2013;84(12):1378-1383."},{"issue":"2","key":"b24","series-title":"Neurol Res","first-page":"164","article-title":"Comparison of seizure outcomes and safety between anterior temporal lobotomy and lobectomy in patients with temporal lobe epilepsy","volume":"42","author":"Yang X","year":"2020","unstructured":"Yang X, Liu Q, Yang Q,  Comparison of seizure outcomes and safety between anterior temporal lobotomy and lobectomy in patients with temporal lobe epilepsy. Neurol Res. 2020;42(2):164-169."},{"key":"b25","series-title":"Front Neurol","first-page":"580221","article-title":"Side of lesions predicts surgical outcomes in patients with drug-resistant temporal lobe epilepsy secondary to focal cortical dysplasia type IIIa","volume":"11","author":"He X","year":"2020","unstructured":"He X, Liu D, Yang Z, Zhang J, Li S, Yang Z. Side of lesions predicts surgical outcomes in patients with drug-resistant temporal lobe epilepsy secondary to focal cortical dysplasia type IIIa. Front Neurol. 2020;11:580221."}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/143\/3\/article-p755.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/143\/3\/article-p755.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/143\/3\/article-p755.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T14:29:18Z","timestamp":1772720958000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/143\/3\/article-p755.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,1]]},"references-count":50,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/2024.10.jns241152","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,1]]}}}