{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T14:52:40Z","timestamp":1794322360562,"version":"4.9.0"},"reference-count":68,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>The aim of this study was to investigate the global variability in intraoperative neurosurgical management strategies for fetal spina bifida surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>All prenatal fetal spina bifida surgery centers identified through the International Society of Prenatal Diagnosis website and previous literature were invited to participate in an online survey addressing various aspects of the surgery, including fetal selection criteria, surgical technique, and common intraoperative challenges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Thirty-four centers (72%) responded to the survey, more than half of whom perform fewer than 10 surgeries annually (56%). The most common earliest gestational age (GA) for fetal surgery was 23 (36%, n = 12\/33), ranging from &lt; 21 weeks (9%, n = 3) to &gt; 24 weeks (9%, n = 3). The latest GA for surgery varied from &lt; 26 weeks (24%, n = 8) to 30 weeks (3%, n = 1), with the majority setting a cutoff at 26 weeks (50%, n = 17). Open fetal surgery is the predominant method in 76% of centers (n = 26), followed by a hybrid approach (laparotomy with fetoscopy on the uterus; 29%, n = 10) and fully percutaneous fetoscopic surgery (15%, n = 5). Filum terminale dissection is performed in 58% (n = 19\/33) of centers and placode tubularization in 46% (n = 15\/33). Myofascial flaps are routinely used in 55% of the centers (n = 18\/33). When primary skin closure is not possible, 39% (n = 13\/33) will use releasing side cuts and one-third of all centers will use acellular dermal matrix grafts (33.3%, n = 11\/33). Extensive skin defects and suboptimal fetal access were commonly cited as the most significant intraoperative challenges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>There is variability in the fetal inclusion criteria and intraoperative management of fetal spina bifida across centers. This variability emphasizes the need for more research on best practices as well as standardized outcome reporting (ideally through \"core outcomes\") to allow for comparison between centers. Identified challenges, such as difficulties in skin closure, highlight specific areas for future innovations in the field.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2024.10.peds24412","type":"journal-article","created":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T22:45:46Z","timestamp":1745016346000},"page":"3-10","source":"Crossref","is-referenced-by-count":4,"title":["Global variability in fetal spina bifida surgery: a survey of neurosurgical strategies"],"prefix":"10.3171","volume":"36","author":[{"given":"Charlotte C.","family":"Kik","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Mount Sinai Hospital, and University of Toronto, Ontario, Canada;"},{"name":"Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yada","family":"Kunpalin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Mount Sinai Hospital, and University of Toronto, Ontario, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhaya V.","family":"Kulkarni","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Hospital for Sick Children, and University of Toronto, Ontario, Canada;"},{"name":"Ontario Fetal Centre, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip L. J.","family":"DeKoninck","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochem K. H.","family":"Spoor","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Van Mieghem","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Mount Sinai Hospital, and University of Toronto, Ontario, Canada;"},{"name":"Ontario Fetal Centre, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"11","key":"b1","series-title":"N Engl J Med","first-page":"993","article-title":"A randomized trial of prenatal versus postnatal repair of myelomeningocele","volume":"364","author":"Adzick NS","year":"2011","unstructured":"Adzick NS, Thom EA, Spong CY,  A randomized trial of prenatal versus postnatal repair of myelomeningocele. 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