{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T20:08:40Z","timestamp":1772827720181,"version":"3.50.1"},"reference-count":86,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Tethered cord syndrome (TCS) is a significant cause of debilitation in patients with spinal dysraphisms or tumors. Management of TCS has historically centered on intradural detethering surgery, which is associated with a substantial risk of retethering, symptom recurrence, and repeat surgery. Vertebral column resection (VCR) has recently gained popularity as a treatment option via spinal shortening, but the literature on long-term outcomes is sparse. The objective of this study was to explore long-term clinical outcomes in a series of patients undergoing VCR for recurrent TCS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A retrospective review was conducted of all consecutive patients undergoing VCR for recurrent TCS at a single center between 2014 and 2024. Demographic and radiological characteristics were recorded, including spinal column height reduction as well as symptom improvement rates regarding sensorimotor dysfunction, pain, and incontinence at the latest follow-up. Intra- and postoperative complications were noted, and pre- and postoperative symptomology was compared using McNemar\u2019s test at a significance level of p &lt; 0.05 to identify improvements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Twenty surgeries in 19 patients (median age 19 years) involving 10 males (52.6%) were assessed. The most common etiology of TCS was lipomyelomeningocele (n = 7, 36.8%), followed by lipoma (n = 6, 31.6%). Patients underwent a mean of 3.4 previous detethering procedures. Osteotomy was most commonly performed at the L1 level (n = 11, 55.0%), and the mean spinal column height reduction was 16.5 mm. At a mean follow-up of 43.1 (range 12\u2013101) months, resolution of symptoms was observed in 10 patients with back pain (71.4%; p = 0.043), 10 patients with leg pain (66.7%; p = 0.004), 9 patients with lower extremity weakness (75.0%; p = 0.008), 4 patients with urinary incontinence (44.4%; p = 0.371), and 1 patient with fecal incontinence (33.3%; p &gt; 0.99). Complications included a CSF leak in 1 patient and repeat VCR in 1 patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>These results suggest that in select patients with recurrent TCS, VCR represents a treatment option with high rates of symptomatic improvement and a relatively low risk of retethering as observed over several years of follow-up. These results add to the body of literature supporting VCR and provide a compelling basis for future prospectively designed studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2024.10.spine24453","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T21:07:35Z","timestamp":1738962455000},"page":"633-640","source":"Crossref","is-referenced-by-count":0,"title":["Posterior vertebral column resection for recurrent tethered cord syndrome: a 10-year case series"],"prefix":"10.3171","volume":"42","author":[{"given":"Harshal A.","family":"Shah","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam M.","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon A.","family":"Santhumayor","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Golub","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roee","family":"Ber","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel M.","family":"Sciubba","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark A.","family":"Mittler","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaun D.","family":"Rodgers","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J.","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"Lefkowitz","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, North Shore University Hospital\/Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"2","key":"b1","series-title":"Neurosurg Clin N Am","first-page":"311","article-title":"Pathophysiology of tethered cord syndrome","volume":"6","author":"Yamada S","year":"1995","unstructured":"Yamada S, Iacono RP, Andrade T, Mandybur G, Yamada BS. 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