{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T15:08:36Z","timestamp":1780412916194,"version":"3.54.1"},"reference-count":68,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Minimally invasive MRI-guided laser interstitial thermal therapy (MRgLITT) is an approach increasingly recognized as an effective tool for treating epileptic foci. Recent literature reports that stereotactic laser amygdalohippocampotomy (SLAH) for mesial temporal lobe epilepsy (MTLE) results in seizure-freedom rates comparable to those of analogous open selective amygdalohippocampectomy with a potentially more favorable neurocognitive adverse effect profile. However, many SLAH series show heterogenous results. The authors\u2019 objectives were to present the largest experience to date using a single MRI-compatible targeting platform (ClearPoint) for SLAH to treat MTLE and to report their analysis of accuracy and intraoperative factors correlated to complications and initial outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The authors retrospectively collected data from all consecutive patients who underwent SLAH for MTLE using a single MRI-compatible targeting platform (ClearPoint) for SLAH at Emory University between June 2013 and October 2019. Univariable analysis, including the Student t-test, 1-way ANOVA, chi-square test, and Wilcoxon rank-sum test, was used to assess the relationship between surgical characteristics and outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>The authors analyzed a total of 91 patients who underwent 97 procedures with 114 total trajectories between June 2013 and October 2019. All patients had a diagnosis of MTLE, as determined by scalp or intracranial EEG, with a mean \u00b1 SD age at surgery of 42.8 \u00b1 12.9 years and a mean seizure onset age of 19.3 \u00b1 14.7 years. The mean number of trajectories was 1.39 \u00b1 0.6 (range 1\u20133), with an overall mean target error of 1.2 \u00b1 1.0 mm (range 0.1\u20134.7 mm). Target errors improved significantly over time, demonstrating a learning effect. Entry-to-target distance was 106.5 \u00b1 11.5 mm (range 62.6\u2013127.3 mm) and did not correlate to error. At the 12-month follow-up, 46 (50.5%) had an Engel score I, 21 (23.1%) had an Engel score II, 16 (17.6%) had an Engel score III, 5 (5.5%) had an Engel score IV, and 3 were lost to follow-up. Of the 66 patients who had mesial temporal sclerosis (MTS), 38 (56%) had Engel score I, 15 (23%) had score II, 9 (14%) had score III, and 3 (4.5%) had score IV at 12 months, with 1 lost to follow-up. Of the 25 patients without MTS, 8 (32%) had Engel score I, 6 (24%) had score II, 7 (28%) had score III, and 2 (8.0%) had score IV at 12 months, with 2 lost to follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>The authors present the largest single-center experience using an MRI-compatible targeting platform for initial SLAH to treat MTLE. This technique results in safe laser ablation of epileptogenic tissue, with seizure outcomes comparable to those reported for open procedures. Further work is needed to validate its advantages over existing stereotactic approaches and the impact of multiple minimally invasive procedures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2024.12.jns241158","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T21:51:42Z","timestamp":1746827502000},"page":"708-717","source":"Crossref","is-referenced-by-count":1,"title":["Accuracy and initial outcomes for stereotactic laser amygdalohippocampotomy using a fully MRI-compatible platform"],"prefix":"10.3171","volume":"143","author":[{"given":"Yifei","family":"Sun","sequence":"first","affiliation":[{"name":"Marnix E. Heersink School of Medicine, University of Alabama at Birmingham, Alabama;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faical","family":"Isbaine","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Emory University, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Nicole","family":"Bentley","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Alabama at Birmingham, Alabama;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Emory University, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yarema B.","family":"Bezchlibnyk","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Emory University, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert E.","family":"Gross","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Robert Wood Johnson Medical School and Rutgers Health New Jersey Medical School, Newark, New Jersey; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon T.","family":"Willie","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Epilepsy Res","first-page":"131","article-title":"MR-guided laser ablation for the treatment of hypothalamic hamartomas","volume":"142","author":"Curry DJ","year":"2018","unstructured":"Curry DJ, Raskin J, Ali I, Wilfong AA. MR-guided laser ablation for the treatment of hypothalamic hamartomas. Epilepsy Res. 2018;142:131\u2013134."},{"issue":"4","key":"b2","series-title":"Neurosurg Focus","first-page":"E11","article-title":"Stereotactic laser ablation as treatment for brain metastases that recur after stereotactic radiosurgery: a multiinstitutional experience","volume":"41","author":"Ali MA","year":"2016","unstructured":"Ali MA, Carroll KT, Rennert RC,  Stereotactic laser ablation as treatment for brain metastases that recur after stereotactic radiosurgery: a multiinstitutional experience. 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Elsevier;2015:375-403."},{"issue":"4","key":"b18","series-title":"J Neurosurg","first-page":"1165","article-title":"Improved operative efficiency using a real-time MRI-guided stereotactic platform for laser amygdalohippocampotomy","volume":"128","author":"Ho AL","year":"2018","unstructured":"Ho AL, Sussman ES, Pendharkar AV,  Improved operative efficiency using a real-time MRI-guided stereotactic platform for laser amygdalohippocampotomy. J Neurosurg. 2018;128(4):1165\u20131172."},{"issue":"12","key":"b19","series-title":"Int J Surg","first-page":"1500","article-title":"Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration","volume":"12","author":"Vandenbroucke JP","year":"2014","unstructured":"Vandenbroucke JP, von Elm E, Altman DG,  Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. Int J Surg. 2014;12(12):1500\u20131524."},{"key":"b20","article-title":"R: A language and environment for statistical computing. R Foundation for Statistical Computing","unstructured":". R: A language and environment for statistical computing. R Foundation for Statistical Computing. Accessed December 23, 2024. https:\/\/www.R-project.org"},{"key":"b21","series-title":"Neurosurgery","first-page":"233","article-title":"202 Role of repeat ablation to treat seizure recurrence following stereotactic laser amygdalohippocampotomy","volume":"62","author":"Willie JT","year":"2015","unstructured":"Willie JT, Gross RE. 202 Role of repeat ablation to treat seizure recurrence following stereotactic laser amygdalohippocampotomy. Neurosurgery. 2015;62:233\u2013234."},{"key":"b22","series-title":"Front Neurol","first-page":"654668","article-title":"Surgical outcomes and EEG prognostic factors after stereotactic laser amygdalohippocampectomy for mesial temporal lobe epilepsy","volume":"12","author":"Wu S","year":"2021","unstructured":"Wu S, Issa NP, Lacy M,  Surgical outcomes and EEG prognostic factors after stereotactic laser amygdalohippocampectomy for mesial temporal lobe epilepsy. Front Neurol. 2021;12:654668."},{"issue":"10","key":"b23","series-title":"Epilepsia","first-page":"2344","article-title":"Two-trajectory laser amygdalohippocampotomy: anatomic modeling and initial seizure outcomes","volume":"62","author":"Liu DD","year":"2021","unstructured":"Liu DD, Lauro PM, Phillips RK III,  Two-trajectory laser amygdalohippocampotomy: anatomic modeling and initial seizure outcomes. Epilepsia. 2021;62(10):2344\u20132356."},{"key":"b24","series-title":"Epilepsy Res","first-page":"135","article-title":"A neurosurgeon\u2019s view: laser interstitial thermal therapy of mesial temporal lobe structures","volume":"142","author":"Bezchlibnyk YB","year":"2018","unstructured":"Bezchlibnyk YB, Willie JT, Gross RE. A neurosurgeon\u2019s view: laser interstitial thermal therapy of mesial temporal lobe structures. Epilepsy Res. 2018;142:135\u2013139."},{"issue":"2","key":"b25","series-title":"J Neurosurg Pediatr","first-page":"214","article-title":"Accuracy of robot-assisted stereotactic MRI-guided laser ablation in children with epilepsy","volume":"32","author":"Lee KS","year":"2023","unstructured":"Lee KS, Seunarine KK, Barnes N, Tahir MZ, Varadkar SM, Tisdall MM. Accuracy of robot-assisted stereotactic MRI-guided laser ablation in children with epilepsy. J Neurosurg Pediatr. 2023;32(2):214\u2013222."},{"issue":"3","key":"b26","series-title":"J Neurosurg Pediatr","first-page":"297","article-title":"Accuracy of robot-assisted versus optical frameless navigated stereoelectroencephalography electrode placement in children","volume":"23","author":"Sharma JD","year":"2019","unstructured":"Sharma JD, Seunarine KK, Tahir MZ, Tisdall MM. Accuracy of robot-assisted versus optical frameless navigated stereoelectroencephalography electrode placement in children. J Neurosurg Pediatr. 2019;23(3):297\u2013302."},{"issue":"3","key":"b27","series-title":"J Robot Surg","first-page":"1013","article-title":"A comparison between robot-guided and stereotactic frame-based stereoelectroencephalography (SEEG) electrode implantation for drug-resistant epilepsy","volume":"17","author":"Yao Y","year":"2023","unstructured":"Yao Y, Hu W, Zhang C,  A comparison between robot-guided and stereotactic frame-based stereoelectroencephalography (SEEG) electrode implantation for drug-resistant epilepsy. J Robot Surg. 2023;17(3):1013\u20131020."},{"issue":"4","key":"b28","series-title":"Ann Palliat Med","first-page":"3699","article-title":"How can the accuracy of SEEG be increased?\u2014an analysis of the accuracy of multilobe-spanning SEEG electrodes based on a frameless stereotactic robot-assisted system","volume":"10","author":"Lu C","year":"2021","unstructured":"Lu C, Chen S, An Y,  How can the accuracy of SEEG be increased?\u2014an analysis of the accuracy of multilobe-spanning SEEG electrodes based on a frameless stereotactic robot-assisted system. Ann Palliat Med. 2021;10(4):3699\u20133705."},{"issue":"4","key":"b29","series-title":"Stereotact Funct Neurosurg","first-page":"255","article-title":"Mechanisms and risk factors contributing to visual field deficits following stereotactic laser amygdalohippocampotomy","volume":"97","author":"Voets NL","year":"2019","unstructured":"Voets NL, Alvarez I, Qiu D,  Mechanisms and risk factors contributing to visual field deficits following stereotactic laser amygdalohippocampotomy. Stereotact Funct Neurosurg. 2019;97(4):255\u2013265."},{"key":"b30","series-title":"Seizure","first-page":"228","article-title":"Comparisons of the seizure-free outcome and visual field deficits between anterior temporal lobectomy and selective amygdalohippocampectomy: a systematic review and meta-analysis","volume":"81","author":"Xu K","year":"2020","unstructured":"Xu K, Wang X, Guan Y,  Comparisons of the seizure-free outcome and visual field deficits between anterior temporal lobectomy and selective amygdalohippocampectomy: a systematic review and meta-analysis. Seizure. 2020;81:228\u2013235."},{"key":"b31","series-title":"Epilepsy Behav","first-page":"108529","article-title":"Patient preferences pertaining to treatment options for drug-resistant focal epilepsy","volume":"127","author":"Sinha SR","year":"2022","unstructured":"Sinha SR, Yang JC, Wallace MJ, Grover K, Johnson FR, Reed SD. Patient preferences pertaining to treatment options for drug-resistant focal epilepsy. Epilepsy Behav. 2022;127:108529."},{"issue":"10","key":"b32","series-title":"Epilepsia","first-page":"2078","article-title":"(Re)defining success in epilepsy surgery: the importance of relative seizure reduction in patient-reported quality of life","volume":"60","author":"Sheikh S","year":"2019","unstructured":"Sheikh S, Thompson N, Bingaman W, Gonzalez-Martinez J, Najm I, Jehi L. (Re)defining success in epilepsy surgery: the importance of relative seizure reduction in patient-reported quality of life. Epilepsia. 2019;60(10):2078\u20132085."},{"key":"b33","series-title":"Epilepsy Behav","first-page":"108659","article-title":"Open surgery or laser interstitial thermal therapy for low-grade epilepsy-associated tumors of the temporal lobe: a single-institution consecutive series","volume":"130","author":"Hedaya AA","year":"2022","unstructured":"Hedaya AA, Hewitt KC, Hu R,  Open surgery or laser interstitial thermal therapy for low-grade epilepsy-associated tumors of the temporal lobe: a single-institution consecutive series. Epilepsy Behav. 2022;130:108659."},{"key":"b34","series-title":"Epilepsy Behav","first-page":"109669","article-title":"Comparison of minimally invasive to standard temporal lobectomy approaches to epilepsy surgery: seizure relief and visual confrontation naming outcomes","volume":"155","author":"Hageboutros K","year":"2024","unstructured":"Hageboutros K, Hewitt KC, Lee GP,  Comparison of minimally invasive to standard temporal lobectomy approaches to epilepsy surgery: seizure relief and visual confrontation naming outcomes. 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