{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T20:40:01Z","timestamp":1784320801048,"version":"3.55.0"},"reference-count":108,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Chordomas are locally aggressive neoplasms of the spine or skull base that arise from embryonic remnants of the notochord. Intradural chordomas represent a rare subset of these neoplasms, and few studies have described intradural chordomas in the spine. This review evaluates the presentation, management, and outcomes of intradural spinal chordomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A systematic review of PubMed\/MEDLINE, EMBASE, Cochrane Library, Scopus, and Web of Science was performed. Studies describing at least 1 case of intradural chordomas anywhere in the spine were included. Extracted details included presenting symptoms, radiological findings, treatment course, follow-up, and disease progression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Thirty-one studies, with a total of 41 patients, were included in this review. Seventy-six percent (31\/41) of patients had primary intradural tumors, whereas 24% (10\/41) presented with metastasis. The most common signs and symptoms were pain (n = 27, 66%); motor deficits (n = 20, 49%); sensory deficits (n = 17, 42%); and gait disturbance (n = 10, 24%). The most common treatment for intradural chordoma was resection and postoperative radiotherapy. Sixty-six percent (19\/29) of patients reported improvement or complete resolution of symptoms after surgery. The recurrence rate was 37% (10\/27), and the complication rate was 25% (6\/24). The median progression-free survival was 24 months (range 4\u201372 months). Four patient deaths were reported. The median follow-up time was 12 months (range 13 days\u201384 months).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Treatment of intradural spinal chordomas primarily involves resection and radiotherapy. A significant challenge and complication in management is spinal tumor seeding after resection, with 9 studies proposing seeding as a mechanism of tumor metastasis in 11 cases. Factors such as tumor size, Ki-67 positivity, and distant metastasis may correlate with worse outcomes and demonstrate potential as prognostic indicators for intradural spinal chordomas. Further research is needed to improve understanding of this tumor and develop optimal treatment paradigms for these patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2024.2.focus2419","type":"journal-article","created":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T04:50:36Z","timestamp":1714798236000},"page":"E14","source":"Crossref","is-referenced-by-count":3,"title":["Characterizing the presentation, management, and clinical outcomes of patients with intradural spinal chordomas: a systematic review"],"prefix":"10.3171","volume":"56","author":[{"given":"Max A.","family":"Saint-Germain","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Kramer","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carly","family":"Weber-Levine","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Jiang","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdel-Hameed","family":"Al-Mistarehi","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin J.","family":"Redmond","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"},{"name":"Radiation Oncology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Orthopedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chetan","family":"Bettegowda","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Theodore","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Lubelski","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"12","key":"b1","series-title":"Eur Spine J","first-page":"3043","article-title":"Chordoma: a systematic review of the epidemiology and clinical prognostic factors predicting progression-free and overall survival","volume":"27","author":"Bakker SH","year":"2018","unstructured":"Bakker SH, Jacobs WCH, Pondaag W,  Chordoma: a systematic review of the epidemiology and clinical prognostic factors predicting progression-free and overall survival. Eur Spine J. 2018;27(12):3043\u20133058."},{"issue":"6","key":"b2","series-title":"J Natl Compr Canc Netw","first-page":"726","article-title":"Diagnosis and treatment of chordoma","volume":"11","author":"Williams BJ","year":"2013","unstructured":"Williams BJ, Raper DM, Godbout E,  Diagnosis and treatment of chordoma. J Natl Compr Canc Netw. 2013;11(6):726\u2013731."},{"issue":"1","key":"b3","series-title":"Cancer Causes Control","first-page":"1","article-title":"Chordoma: incidence and survival patterns in the United States, 1973-1995","volume":"12","author":"McMaster ML","year":"2001","unstructured":"McMaster ML, Goldstein AM, Bromley CM, Ishibe N, Parry DM. Chordoma: incidence and survival patterns in the United States, 1973-1995. Cancer Causes Control. 2001;12(1):1\u201311."},{"issue":"4","key":"b4","series-title":"Int J Cancer","first-page":"E508","article-title":"Incidence and survival of malignant bone sarcomas in England 1979-2007","volume":"131","author":"Whelan J","year":"2012","unstructured":"Whelan J, McTiernan A, Cooper N,  Incidence and survival of malignant bone sarcomas in England 1979-2007. Int J Cancer. 2012;131(4):E508\u2013E517."},{"key":"b5","series-title":"BMC Cancer","first-page":"22","article-title":"Chordoma: clinical characteristics, management and prognosis of a case series of 25 patients","volume":"10","author":"Ferraresi V","year":"2010","unstructured":"Ferraresi V, Nuzzo C, Zoccali C,  Chordoma: clinical characteristics, management and prognosis of a case series of 25 patients. BMC Cancer. 2010;10:22."},{"issue":"5","key":"b6","series-title":"Am J Clin Pathol","first-page":"765","article-title":"A clinicopathologic study of metastasis","volume":"72","author":"Chambers PW","year":"1979","unstructured":"Chambers PW, Schwinn CP. Chordoma. A clinicopathologic study of metastasis. Am J Clin Pathol. 1979;72(5):765\u2013776."},{"issue":"3","key":"b7","series-title":"Cancer","first-page":"735","article-title":"Chordoma of the mobile spine. A clinicopathologic analysis of 40 patients","volume":"71","author":"Bjornsson J","year":"1993","unstructured":"Bjornsson J, Wold LE, Ebersold MJ, Laws ER. Chordoma of the mobile spine. A clinicopathologic analysis of 40 patients. 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J Neurosurg","first-page":"236","article-title":"Spinal chordoma of the terminal filum","volume":"96","author":"Bayar MA","year":"2002","unstructured":"Bayar MA, Erdem Y, Tanyel O, Ozturk K, Buharali Z. Spinal chordoma of the terminal filum. Case report. J Neurosurg. 2002;96(2 Suppl):236\u2013238."},{"issue":"3","key":"b17","series-title":"Clin Neuropathol","first-page":"169","article-title":"Primary intradural chordoma: report on three cases and review of the literature","volume":"29","author":"Bergmann M","year":"2010","unstructured":"Bergmann M, Abdalla Y, Neubauer U, Schildhaus HU, Probst-Cousin S. Primary intradural chordoma: report on three cases and review of the literature. 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Chin Med J (Engl). 2008;121(12):1150\u20131152."},{"issue":"11","key":"b25","series-title":"Neurol Med Chir (Tokyo)","first-page":"930","article-title":"Simultaneous discovery of cranial and spinal intradural chordomas: case report","volume":"54","author":"Kawanabe Y","year":"2014","unstructured":"Kawanabe Y, Ueda S, Sasaki N, Hoshimaru M. Simultaneous discovery of cranial and spinal intradural chordomas: case report. Neurol Med Chir (Tokyo). 2014;54(11):930\u2013935."},{"issue":"1","key":"b26","series-title":"AJNR Am J Neuroradiol","first-page":"193","article-title":"Intradural metastases of chordoma","volume":"10","author":"Krol G","year":"1989","unstructured":"Krol G, Sze G, Arbit E, Marcove R, Sundaresan N. Intradural metastases of chordoma. 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