{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:48:25Z","timestamp":1792806505985,"version":"4.5.0"},"reference-count":54,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>The recent introduction of the Woven EndoBridge (WEB) has presented an alternative treatment modality for intracranial bifurcation and wide-neck aneurysms with a growing body of literature evaluating its efficacy. However, no previous systematic review has focused on comparing WEB with previously using endovascular approaches, specifically primary coiling (PC) and stent-assisted coiling (SAC). Herein, the authors present the first systematic review summarizing available literature to reach a consensus regarding the safety and effectiveness of WEB.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>A systematic review of articles identified through a search of PubMed, Embase, Scopus, and Web of Science was conducted. Studies were included if they compared WEB with PC or SAC from any aspect for intracranial aneurysms. Risk of bias was assessed using the Risk of Bias in Non-Randomized Studies\u2013of Interventions tool. Meta-analyses of the outcomes based on stent use and rupture status were performed.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>A total of 16 studies were included. The three endovascular approaches were comparable in terms of baseline characteristics except for older age and smaller aneurysm neck in the PC group (p &lt; 0.05). Moreover, the follow-up duration was shorter in the WEB group (p &lt; 0.05). Although the WEB group demonstrated lower complete and adequate immediate occlusion rates (p &lt; 0.01), the rates at follow-up evaluations were comparable with SAC and PC (p = 0.61 and p = 0.27, respectively). The WEB group experienced significantly fewer unfavorable neurological outcomes than the SAC group (p = 0.04), while comparable to the PC group (p = 0.36). Retreatment rates were comparable between WEB and coiling (p = 0.92). The WEB group had fewer hemorrhagic and thromboembolic complications (p &lt; 0.01 and p = 0.01, respectively), with similar neurological and procedure-related complications compared with combined PC and SAC groups. Lastly, mortality was comparable among the different endovascular approaches.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>This study provides evidence on the noninferiority of WEB compared with PC and SAC in terms of angiographic outcomes. Meanwhile, our findings on lower complication rates, cost, and improved operative aspects associated with WEB establish this novel endovascular treatment as a safe and effective alternative for the treatment of bifurcation and wide-neck aneurysms.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2024.2.jns232531","type":"journal-article","created":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T03:02:01Z","timestamp":1715396521000},"page":"1026-1039","source":"Crossref","is-referenced-by-count":14,"title":["Comparison between Woven EndoBridge and coiling with and without stent assistance for intracranial bifurcation and wide-neck aneurysms: a comprehensive systematic review and meta-analysis"],"prefix":"10.3171","volume":"141","author":[{"given":"Seyed Farzad","family":"Maroufi","sequence":"first","affiliation":[{"name":"Neurosurgical Research Network (NRN), Universal Scientific Education and Research Network (USERN), Tehran, Iran;"},{"name":"Department of Neurosurgery, Tehran University of Medical Sciences, Tehran, Iran;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Sadegh","family":"Fallahi","sequence":"additional","affiliation":[{"name":"Neurosurgical Research Network (NRN), Universal Scientific Education and Research Network (USERN), Tehran, Iran;"},{"name":"Department of Neurosurgery, Tehran University of Medical Sciences, Tehran, Iran;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Waqas","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elad I.","family":"Levy","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"},{"name":"Department of Neurosurgery, Gates Vascular Institute at Kaleida Health, Buffalo;"},{"name":"Jacobs Institute, Buffalo; and"},{"name":"Radiology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo;"},{"name":"Canon Stroke and Vascular Research Center, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"8","key":"b1","series-title":"Stroke","first-page":"e523","article-title":"Coiling of intracranial aneurysms: a systematic review on initial occlusion and reopening and retreatment rates","volume":"40","author":"Ferns SP","year":"2009","unstructured":"Ferns SP, Sprengers ME, van Rooij WJ,  Coiling of intracranial aneurysms: a systematic review on initial occlusion and reopening and retreatment rates. 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