{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T05:19:48Z","timestamp":1793769588926,"version":"4.6.1"},"reference-count":45,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>Lumbar disc herniation (LDH) is rare in young adults. The present study aimed to evaluate the clinical outcomes of full-endoscopic lumbar discectomy (FELD) for LDH in young adults and to determine the risk factors that predict unfavorable outcomes of FELD for LDH in young adults.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>A retrospective two-center cohort study was performed between January 2015 and October 2021 at the authors\u2019 institutions. Clinical outcomes were assessed using the visual analog scale (VAS) for low-back pain and leg pain and the Oswestry Disability Index (ODI). The modified Macnab criteria were used to evaluate clinical efficacy at the last follow-up, and the global outcomes were classified into 4 groups, namely excellent, good, fair, and poor. The fair and poor groups were defined as unfavorable outcomes.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>One hundred ninety-nine patients were analyzed in this study (mean age 18.5 years, mean BMI 25.1 kg\/m<jats:sup>2<\/jats:sup>, male\/female sex ratio 2.8). The duration from the onset of symptoms to the operation was in general prolonged with age. The VAS and ODI scores significantly improved after surgery. A total of 17 of 195 single-segment cases had unfavorable outcomes based on the modified Macnab criteria. Lateral disc herniation (OR 3.72, 95% CI 1.14\u201312.12, p = 0.029) and high preoperative VAS score (OR 1.98, 95% CI 1.13\u20133.46, p = 0.017) were identified as risk factors for unfavorable outcomes after FELD.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>FELD for LDH in young adults is safe and effective. Preoperative VAS score and lateral disc herniation are risk factors of nonfavorable outcomes after surgery and may be a useful index for surgical procedure selection.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2024.4.spine231011","type":"journal-article","created":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T01:59:11Z","timestamp":1719626351000},"page":"369-377","source":"Crossref","is-referenced-by-count":6,"title":["Full-endoscopic lumbar discectomy for lumbar disc herniation in young adults: 199 consecutive cases treated by a single surgeon with a mean 3.7-year follow-up"],"prefix":"10.3171","volume":"41","author":[{"given":"Fei","family":"Feng","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rugang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Beijing Ditan Hospital, Capital Medical University, Chaoyang District, Beijing; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huajun","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingjia","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoguang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Haidian District, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"2","key":"b1","series-title":"J Back Musculoskeletal Rehabil","first-page":"323","article-title":"The substantial clinical benefit of comprehensively considering low back pain and radiating pain caused by lumbar intervertebral disc herniation","volume":"35","author":"Jeon SH","year":"2022","unstructured":"Jeon SH, Yang YM, Lee YJ, Kim MR, Kim EJ, Ha IH. 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