{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T20:44:12Z","timestamp":1789418652305,"version":"build-2803163510"},"reference-count":23,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>The Contour Neurovascular System (CNS) is a novel intrasaccular flow-disrupting device for the treatment of intracranial aneurysms. This study presents the authors\u2019 institutional experience and midterm follow-up results with this device.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS <\/jats:title>\n<jats:p>Seventy-six consecutive patients (mean \u00b1 SD age 58.9 \u00b1 12.4 years) were treated with the CNS for 76 aneurysms (63 unruptured, 10 recurrent, and 3 ruptured). Aneurysm characteristics, procedural details, and clinical\/angiographic outcomes were retrospectively evaluated.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>The most common aneurysm locations were the basilar tip in 25 (32.9%) cases and the anterior communicating artery in 22 (28.9%). There were 18 (23.7%) sidewall aneurysms. The mean \u00b1 SD aneurysm width was 5.6 \u00b1 2.5 mm, and 68 (89.5%) aneurysms were wide-necked. The CNS was successfully implanted in 68 (89.5%) aneurysms, with 11 cases of additional coiling and 1 case each of additional stent and balloon. There were 3 (3.9%) thromboembolic events, of which 1 (1.3%) was symptomatic (a major ischemic stroke) and resulted in morbidity. There were no hemorrhagic events or deaths. At last available follow-up (mean 12 months), 32\/56 (57.1%) aneurysms were completely occluded, 16\/56 (28.6%) had neck remnants, and 8\/56 (14.3%) had an aneurysm remnant. Three (5.4%) aneurysms were retreated.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>The use of the CNS was safe and feasible but proper aneurysm selection appears to be required, which may be facilitated with increasing operator experience and further study of this device. Similar to other intrasaccular flow disrupters, midterm complete occlusion rates are moderate but may increase with longer follow-up.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/2024.5.jns232852","type":"journal-article","created":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T01:27:29Z","timestamp":1723858049000},"page":"1-9","source":"Crossref","is-referenced-by-count":8,"title":["Safety and efficacy of the Contour Neurovascular System for intracranial aneurysm treatment: a retrospective analysis of 76 patients"],"prefix":"10.3171","author":[{"given":"Alexandra","family":"Radomi","sequence":"first","affiliation":[{"name":"Department of Neuroradiology, University Hospital Munich (LMU), Munich, Germany; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Goertz","sequence":"additional","affiliation":[{"name":"Department of Radiology and Neuroradiology, University of Cologne, Faculty of Medicine and University Hospital, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Forbrig","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University Hospital Munich (LMU), Munich, Germany; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muriel","family":"Pflaeging","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University Hospital Munich (LMU), Munich, Germany; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Kabbasch","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University Hospital Munich (LMU), Munich, Germany; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Liebig","sequence":"additional","affiliation":[{"name":"Department of Radiology and Neuroradiology, University of Cologne, Faculty of Medicine and University Hospital, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"6","key":"b1","series-title":"J Neurointerv Surg","first-page":"552","article-title":"Aneurysm treatment with the Woven EndoBridge (WEB) device in the combined population of two prospective, multicenter series: 5-year follow-up","volume":"15","author":"Pierot L","year":"2023","unstructured":"Pierot L, Szikora I, Barreau X,  Aneurysm treatment with the Woven EndoBridge (WEB) device in the combined population of two prospective, multicenter series: 5-year follow-up. 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Neurointervention. 2021;16(3):211\u2013221."},{"issue":"3","key":"b4","series-title":"Neurosurgery","first-page":"270","article-title":"The safety and effectiveness of the Contour Neurovascular System (Contour) for the treatment of bifurcation aneurysms: the CERUS study","volume":"90","author":"Liebig T","year":"2022","unstructured":"Liebig T, Killer-Oberpfalzer M, Gal G,  The safety and effectiveness of the Contour Neurovascular System (Contour) for the treatment of bifurcation aneurysms: the CERUS study. Neurosurgery. 2022;90(3):270\u2013277."},{"issue":"10","key":"b5","series-title":"J Neurointerv Surg","first-page":"987","article-title":"Endovascular treatment of wide-necked intracranial aneurysms using the novel Contour Neurovascular System: a single-center safety and feasibility study","volume":"12","author":"Akhunbay-Fudge CY","year":"2020","unstructured":"Akhunbay-Fudge CY, Deniz K, Tyagi AK, Patankar T. 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