{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T09:07:15Z","timestamp":1779527235668,"version":"3.53.1"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:p>MR-guided focused ultrasound (MRgFUS) has proven its efficacy and safety for the treatment of essential tremor (ET) and\/or Parkinson\u2019s disease (PD). However, having a cardiac pacemaker has been considered an exclusion criterion for the use of MRgFUS. Only 2 patients with a cardiac pacemaker treated with MRgFUS have been previously reported, both treated using 1.5-T MRI. In this paper, the authors present their experience performing 3-T MRgFUS thalamotomy in 4 patients with an implanted cardiac pacemaker. Treatments were uneventful regarding complications or severe side effects. MRgFUS using 3-T MRI was found to be an efficient and safe treatment for ET and\/or PD in patients with an MRI-compatible pacemaker.<\/jats:p>","DOI":"10.3171\/2024.6.focus24171","type":"journal-article","created":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T09:09:09Z","timestamp":1725181749000},"page":"E5","source":"Crossref","is-referenced-by-count":2,"title":["3-T MR-guided focused ultrasound thalamotomy for tremor in patients with a cardiac pacemaker: case series and review of the literature"],"prefix":"10.3171","volume":"57","author":[{"given":"Lain H.","family":"Gonzalez-Quarante","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Clinica Universidad de Navarra, Pamplona;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Gonzalez-Crespo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Clinica Universidad de Navarra, Pamplona;"},{"name":"Department of Neurosurgery, Hospital Universitario Germans Trias I Pujol, Badalona, Barcelona;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alana","family":"Arcadi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Clinica Universidad de Navarra, Pamplona;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Macias-de-la-Corte","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Clinica Universidad de Navarra, Pamplona;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iciar","family":"Aviles-Olmos","sequence":"additional","affiliation":[{"name":"Department of Neurology, Clinica Universidad de Navarra, Pamplona;"},{"name":"IdiSNA, Instituto de Investigaci\u00f3n Sanitaria de Navarra, Pamplona, Spain; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos A.","family":"Sanchez-Catasus","sequence":"additional","affiliation":[{"name":"Department of Neurology, Clinica Universidad de Navarra, Pamplona;"},{"name":"Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Cacho-Asenjo","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care, Clinica Universidad de Navarra, Pamplona;"},{"name":"IdiSNA, Instituto de Investigaci\u00f3n Sanitaria de Navarra, Pamplona, Spain; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Honorato-Cia","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care, Clinica Universidad de Navarra, Pamplona;"},{"name":"IdiSNA, Instituto de Investigaci\u00f3n Sanitaria de Navarra, Pamplona, Spain; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Martinez-Simon","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care, Clinica Universidad de Navarra, Pamplona;"},{"name":"IdiSNA, Instituto de Investigaci\u00f3n Sanitaria de Navarra, Pamplona, Spain; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arantza","family":"Gorospe","sequence":"additional","affiliation":[{"name":"Department of Neurology, Clinica Universidad de Navarra, Pamplona;"},{"name":"IdiSNA, Instituto de Investigaci\u00f3n Sanitaria de Navarra, Pamplona, Spain; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Martin-Bastida","sequence":"additional","affiliation":[{"name":"Department of Neurology, Clinica Universidad de Navarra, Pamplona;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Corral-Alonso","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Clinica Universidad de Navarra, Pamplona;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C.","family":"Rodriguez-Oroz","sequence":"additional","affiliation":[{"name":"Department of Neurology, Clinica Universidad de Navarra, Pamplona;"},{"name":"IdiSNA, Instituto de Investigaci\u00f3n Sanitaria de Navarra, Pamplona, Spain; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Guridi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Clinica Universidad de Navarra, Pamplona;"},{"name":"IdiSNA, Instituto de Investigaci\u00f3n Sanitaria de Navarra, Pamplona, Spain; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"7","key":"B1","series-title":"N Engl J Med","first-page":"640","article-title":"A pilot study of focused ultrasound thalamotomy for essential tremor","volume":"369","author":"Elias WJ","year":"2013","unstructured":"Elias WJ, Huss D, Voss T,  A pilot study of focused ultrasound thalamotomy for essential tremor. 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J Neurol Neurosurg Psychiatry. 2021;92(5):549\u2013554."},{"issue":"12","key":"B4","series-title":"JAMA Neurol","first-page":"1412","article-title":"Safety and efficacy of focused ultrasound thalamotomy for patients with medication-refractory, tremor-dominant Parkinson disease: a randomized clinical trial","volume":"74","author":"Bond AE","year":"2017","unstructured":"Bond AE, Shah BB, Huss DS,  Safety and efficacy of focused ultrasound thalamotomy for patients with medication-refractory, tremor-dominant Parkinson disease: a randomized clinical trial. 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Feasibility of magnetic resonance-guided focused ultrasound thalamotomy for essential tremor in the setting of prior craniotomy. Oper Neurosurg (Hagerstown). 2022;22(2):61\u201365."},{"issue":"3","key":"B9","series-title":"Mov Disord Clin Pract","first-page":"339","article-title":"Magnetic resonance imaging-guided focused ultrasound thalamotomy for Parkinson\u2019s disease with cardiac pacemaker: a case report","volume":"5","author":"Ito H","year":"2018","unstructured":"Ito H, Fukutake S, Yamamoto K,  Magnetic resonance imaging-guided focused ultrasound thalamotomy for Parkinson\u2019s disease with cardiac pacemaker: a case report. Mov Disord Clin Pract. 2018;5(3):339\u2013340."},{"issue":"3","key":"B10","series-title":"Rev Esp Cardiol (Engl Ed)","first-page":"183","article-title":"Magnetic resonance in patients with cardiovascular devices. 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Mov Disord Clin Pract. 2021;8(5):701\u2013708."},{"issue":"6","key":"B12","series-title":"Mov Disord","first-page":"1015","article-title":"Magnetic resonance-guided focused ultrasound (MRgFUS)-thalamotomy for essential tremor: lesion location and clinical outcomes","volume":"39","author":"Arcadi A","year":"2024","unstructured":"Arcadi A, Aviles-Olmos I, Gonzalez-Quarante LH,  Magnetic resonance-guided focused ultrasound (MRgFUS)-thalamotomy for essential tremor: lesion location and clinical outcomes. Mov Disord. 2024;39(6):1015\u20131025."},{"issue":"1","key":"B13","series-title":"Public Health Rep","first-page":"42","article-title":"The epidemiology of pacemaker implantation in the United States","volume":"110","author":"Silverman BG","year":"1995","unstructured":"Silverman BG, Gross TP, Kaczmarek RG, Hamilton P, Hamburger S. The epidemiology of pacemaker implantation in the United States. 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Phys Med. 2005;21(1):5\u201313."},{"issue":"7","key":"B1","series-title":"N Engl J Med","first-page":"640","article-title":"A pilot study of focused ultrasound thalamotomy for essential tremor","volume":"369","author":"Elias WJ","year":"2013","unstructured":"Elias WJ, Huss D, Voss T,  A pilot study of focused ultrasound thalamotomy for essential tremor. N Engl J Med. 2013;369(7):640\u2013648."},{"issue":"8","key":"B2","series-title":"N Engl J Med","first-page":"730","article-title":"A randomized trial of focused ultrasound thalamotomy for essential tremor","volume":"375","author":"Elias WJ","year":"2016","unstructured":"Elias WJ, Lipsman N, Ondo WG,  A randomized trial of focused ultrasound thalamotomy for essential tremor. 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JAMA Neurol. 2017;74(12):1412\u20131418."},{"issue":"2","key":"B5","series-title":"J Neurosurg","first-page":"417","article-title":"Magnetic resonance-guided focused ultrasound thalamotomy for essential tremor: a 5-year single-center experience","volume":"133","author":"Sinai A","year":"2019","unstructured":"Sinai A, Nassar M, Eran A,  Magnetic resonance-guided focused ultrasound thalamotomy for essential tremor: a 5-year single-center experience. J Neurosurg. 2019;133(2):417\u2013424."},{"issue":"4","key":"B6","series-title":"Stereotact Funct Neurosurg","first-page":"263","article-title":"Focused ultrasound thalamotomy with dentato-rubro-thalamic tractography in patients with spinal cord stimulators and cardiac pacemakers","volume":"98","author":"Buch VP","year":"2020","unstructured":"Buch VP, McShane BJ, Beatson N,  Focused ultrasound thalamotomy with dentato-rubro-thalamic tractography in patients with spinal cord stimulators and cardiac pacemakers. Stereotact Funct Neurosurg. 2020;98(4):263\u2013269."},{"issue":"4","key":"B7","series-title":"Oper Neurosurg (Hagerstown)","first-page":"376","article-title":"Focused ultrasound thalamotomy for essential tremor in the setting of a ventricular shunt: technical report","volume":"17","author":"Yang AI","year":"2019","unstructured":"Yang AI, Chaibainou H, Wang S,  Focused ultrasound thalamotomy for essential tremor in the setting of a ventricular shunt: technical report. Oper Neurosurg (Hagerstown). 2019;17(4):376\u2013381."},{"issue":"2","key":"B8","series-title":"Oper Neurosurg (Hagerstown)","first-page":"61","article-title":"Feasibility of magnetic resonance-guided focused ultrasound thalamotomy for essential tremor in the setting of prior craniotomy","volume":"22","author":"Wathen C","year":"2022","unstructured":"Wathen C, Yang AI, Hitti FL, Henry L, Chaibainou H, Baltuch GH. 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Mov Disord Clin Pract. 2021;8(5):701\u2013708."},{"issue":"6","key":"B12","series-title":"Mov Disord","first-page":"1015","article-title":"Magnetic resonance-guided focused ultrasound (MRgFUS)-thalamotomy for essential tremor: lesion location and clinical outcomes","volume":"39","author":"Arcadi A","year":"2024","unstructured":"Arcadi A, Aviles-Olmos I, Gonzalez-Quarante LH,  Magnetic resonance-guided focused ultrasound (MRgFUS)-thalamotomy for essential tremor: lesion location and clinical outcomes. Mov Disord. 2024;39(6):1015\u20131025."},{"issue":"1","key":"B13","series-title":"Public Health Rep","first-page":"42","article-title":"The epidemiology of pacemaker implantation in the United States","volume":"110","author":"Silverman BG","year":"1995","unstructured":"Silverman BG, Gross TP, Kaczmarek RG, Hamilton P, Hamburger S. The epidemiology of pacemaker implantation in the United States. Public Health Rep. 1995;110(1):42\u201346."},{"issue":"4","key":"B14","series-title":"Pacing Clin Electrophysiol","first-page":"326","article-title":"Current clinical issues for MRI scanning of pacemaker and defibrillator patients","volume":"28","author":"Kalin R","year":"2005","unstructured":"Kalin R, Stanton MS. Current clinical issues for MRI scanning of pacemaker and defibrillator patients. Pacing Clin Electrophysiol. 2005;28(4):326\u2013328."},{"issue":"9","key":"B15","series-title":"Cureus","first-page":"e3374","article-title":"The utility of magnetic resonance imaging-compatible pacemakers in neurosurgical patients","volume":"10","author":"Basil G","year":"2018","unstructured":"Basil G, Madhavan K, Komotar RJ, Carrillo R, Levi AD. The utility of magnetic resonance imaging-compatible pacemakers in neurosurgical patients. 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