{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:05:50Z","timestamp":1782864350966,"version":"3.54.5"},"reference-count":20,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p>This video article presents a case study of a 70-year-old male with medically refractory essential tremor treated with magnetic resonance\u2013guided focused ultrasound (MRgFUS). Following an initial successful ablation of the right thalamus, the patient underwent left-sided thalamotomy. After two tractography-guided sonications, the authors observed a significant reduction in his right-hand tremor with no immediate side effects. Postprocedure evaluation revealed sustained tremor reduction with minimal side effects, showcasing bilateral MRgFUS as an effective, noninvasive option for essential tremor management.<\/jats:p>\n                  <jats:p>\n                    The video can be found here:\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/stream.cadmore.media\/r10.3171\/2024.7.FOCVID2483\">https:\/\/stream.cadmore.media\/r10.3171\/2024.7.FOCVID2483<\/jats:ext-link>\n                  <\/jats:p>","DOI":"10.3171\/2024.7.focvid2483","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T09:20:40Z","timestamp":1727774440000},"page":"V2","source":"Crossref","is-referenced-by-count":2,"title":["Four-tract tractography: multiparametric direct targeting of the dentatorubrothalamic tract"],"prefix":"10.3171","volume":"11","author":[{"given":"Andreas","family":"Seas","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina;"},{"name":"Department of Biomedical Engineering, Duke Pratt School of Engineering, Durham, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina","family":"Hon","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne","family":"Todd","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavya R.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Radiology, Transcranial Focused Ultrasound Laboratory and Program, UTSW Medical Center, Dallas, Texas;"},{"name":"Departments of Radiology, Neuroradiology and Neuro-intervention Section and"},{"name":"Neurological Surgery, UTSW Medical Center, Dallas, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivanand P.","family":"Lad","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Harward","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"8","key":"b1","series-title":"N Engl J Med","first-page":"730","article-title":"A randomized trial of focused ultrasound thalamotomy for essential tremor","volume":"375","author":"Elias WJ","year":"2016","unstructured":"Elias WJ, Lipsman N, Ondo WG,  A randomized trial of focused ultrasound thalamotomy for essential tremor. N Engl J Med. 2016;375(8):730\u2013739."},{"issue":"2","key":"b2","series-title":"Neurosurg Focus","first-page":"E3","article-title":"Transcranial magnetic resonance imaging-guided focused ultrasound thalamotomy for tremor: technical note","volume":"44","author":"Wang TR","year":"2018","unstructured":"Wang TR, Bond AE, Dallapiazza RF,  Transcranial magnetic resonance imaging-guided focused ultrasound thalamotomy for tremor: technical note. Neurosurg Focus. 2018;44(2):E3."},{"issue":"6","key":"b3","series-title":"Brain Commun","first-page":"fcac273","article-title":"Focused ultrasound using a novel targeting method four-tract tractography for magnetic resonance-guided high-intensity focused ultrasound targeting","volume":"4","author":"Feltrin FS","year":"2022","unstructured":"Feltrin FS, Chopra R, Pouratian N,  Focused ultrasound using a novel targeting method four-tract tractography for magnetic resonance-guided high-intensity focused ultrasound targeting. Brain Commun. 2022;4(6):fcac273."},{"issue":"4","key":"b4","series-title":"Brain Commun","first-page":"fcad165","article-title":"Improving tremor response to focused ultrasound thalamotomy","volume":"5","author":"Holcomb JM","year":"2023","unstructured":"Holcomb JM, Chopra R, Feltrin FS,  Improving tremor response to focused ultrasound thalamotomy. Brain Commun. 2023;5(4):fcad165."},{"issue":"9","key":"b5","series-title":"J Neurol Neurosurg Psychiatry","first-page":"927","article-title":"Bilateral staged magnetic resonance-guided focused ultrasound thalamotomy for the treatment of essential tremor: a case series study","volume":"92","author":"Mart\u00ednez-Fern\u00e1ndez R","year":"2021","unstructured":"Mart\u00ednez-Fern\u00e1ndez R, Mahendran S, Pineda-Pardo JA,  Bilateral staged magnetic resonance-guided focused ultrasound thalamotomy for the treatment of essential tremor: a case series study. J Neurol Neurosurg Psychiatry. 2021;92(9):927\u2013931."},{"issue":"11","key":"b6","series-title":"Mov Disord","first-page":"2653","article-title":"Bilateral Focused Ultrasound Thalamotomy for Essential Tremor (BEST-FUS Phase 2 Trial)","volume":"36","author":"Iorio-Morin C","year":"2021","unstructured":"Iorio-Morin C, Yamamoto K, Sarica C,  Bilateral Focused Ultrasound Thalamotomy for Essential Tremor (BEST-FUS Phase 2 Trial). Mov Disord. 2021;36(11):2653\u20132662."},{"issue":"1","key":"b7","series-title":"Mov Disord Clin Pract (Hoboken)","first-page":"60","article-title":"Comparison of the Fahn-Tolosa-Marin Clinical Rating Scale and the Essential Tremor Rating Assessment Scale","volume":"5","author":"Ondo W","year":"2017","unstructured":"Ondo W, Hashem V, LeWitt PA,  Comparison of the Fahn-Tolosa-Marin Clinical Rating Scale and the Essential Tremor Rating Assessment Scale. Mov Disord Clin Pract (Hoboken). 2017;5(1):60-65."},{"issue":"11","key":"b8","series-title":"Neurology","first-page":"1717","article-title":"Scale for the assessment and rating of ataxia: development of a new clinical scale","volume":"66","author":"Schmitz-H\u00fcbsch T","year":"2006","unstructured":"Schmitz-H\u00fcbsch T, du Montcel ST, Baliko L,  Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology. 2006;66(11):1717\u20131720."},{"issue":"12","key":"b9","series-title":"Brain Sci","first-page":"1015","article-title":"Selecting the most effective DBS contact in essential tremor patients based on individual tractography","volume":"10","author":"Petry-Schmelzer JN","year":"2020","unstructured":"Petry-Schmelzer JN, Dembek TA, Steffen JK,  Selecting the most effective DBS contact in essential tremor patients based on individual tractography. Brain Sci. 2020;10(12):1015."},{"key":"b10","series-title":"Parkinsons Dis","first-page":"8124624","article-title":"MRI-guided focused ultrasound in Parkinson\u2019s disease: a review","volume":"2017","author":"Schlesinger I","year":"2017","unstructured":"Schlesinger I, Sinai A, Zaaroor M. MRI-guided focused ultrasound in Parkinson\u2019s disease: a review. Parkinsons Dis. 2017;2017:8124624."},{"issue":"8","key":"b1","series-title":"N Engl J Med","first-page":"730","article-title":"A randomized trial of focused ultrasound thalamotomy for essential tremor","volume":"375","author":"Elias WJ","year":"2016","unstructured":"Elias WJ, Lipsman N, Ondo WG,  A randomized trial of focused ultrasound thalamotomy for essential tremor. 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Mov Disord Clin Pract (Hoboken). 2017;5(1):60-65."},{"issue":"11","key":"b8","series-title":"Neurology","first-page":"1717","article-title":"Scale for the assessment and rating of ataxia: development of a new clinical scale","volume":"66","author":"Schmitz-H\u00fcbsch T","year":"2006","unstructured":"Schmitz-H\u00fcbsch T, du Montcel ST, Baliko L,  Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology. 2006;66(11):1717\u20131720."},{"issue":"12","key":"b9","series-title":"Brain Sci","first-page":"1015","article-title":"Selecting the most effective DBS contact in essential tremor patients based on individual tractography","volume":"10","author":"Petry-Schmelzer JN","year":"2020","unstructured":"Petry-Schmelzer JN, Dembek TA, Steffen JK,  Selecting the most effective DBS contact in essential tremor patients based on individual tractography. 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Parkinsons Dis. 2017;2017:8124624."}],"container-title":["Neurosurgical Focus: Video"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/neurosurg-focus-video\/11\/2\/article-pV2.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/neurosurg-focus-video\/11\/2\/article-pV2.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/neurosurg-focus-video\/11\/2\/article-pV2.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T23:41:43Z","timestamp":1782862903000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/neurosurg-focus-video\/11\/2\/article-pV2.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":20,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3171\/2024.7.focvid2483","relation":{},"ISSN":["2643-5217"],"issn-type":[{"value":"2643-5217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}