{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T13:19:41Z","timestamp":1782220781153,"version":"3.54.5"},"reference-count":42,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Venous sinus stent placement is an increasingly common endovascular technique for treating medically refractory symptoms related to idiopathic intracranial hypertension (IIH). Given that data suggest that a considerable number of patients experience symptom relapse or recurrence, understanding prognosticators of treatment failure is of particular interest.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The authors performed a single-center retrospective review of the medical records of surgically naive patients with IIH who underwent unilateral transverse sinus stent (TSS) placement. Pre-stent clinical, anatomical, and manometric variables were evaluated against post-stent outcomes to determine significant predictors of unfavorable outcomes after treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Forty-two surgically naive patients with IIH underwent unilateral TSS insertion between April 2011 and February 2024. At a mean follow-up of 41 months, 47.6% had ongoing symptoms, 38.1% received escalated medical therapy, 23.8% underwent stent restenosis, and 23.8% underwent procedural retreatment. Younger age at the time of initial stent insertion was associated with post-stent operative retreatment (OR 1.15, p = 0.04), while lower pre-stent BMI predicted resolution of papilledema (OR 0.84, p = 0.003). Higher pre-stent BMI and lower pre-stent pressure gradients were associated with several unfavorable outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Modifiable and unmodifiable risk factors may impact TSS durability for IIH. Larger multicenter studies are warranted to stratify risk for futile TSS outcomes and characterize the ideal IIH candidate for therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2025.10.focus25866","type":"journal-article","created":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T05:51:53Z","timestamp":1767246713000},"page":"E11","source":"Crossref","is-referenced-by-count":2,"title":["Influence of clinical, anatomical, and manometric factors on unilateral transverse sinus stent placement for idiopathic intracranial hypertension"],"prefix":"10.3171","volume":"60","author":[{"given":"Bobak F.","family":"Khalili","sequence":"first","affiliation":[{"name":"Department of Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shehbaz","family":"Ansari","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology & Nuclear Medicine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Chojnacki","sequence":"additional","affiliation":[{"name":"Rush Medical College,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krunal","family":"Patel","sequence":"additional","affiliation":[{"name":"Rush Medical College,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fae B.","family":"Kayarian","sequence":"additional","affiliation":[{"name":"Department of Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bichun","family":"Ouyang","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Webster","family":"Crowley","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"21","key":"b1","series-title":"Circulation","first-page":"e661","article-title":"Indications for the performance of intracranial endovascular neurointerventional procedures: a scientific statement from the American Heart Association","volume":"137","author":"Eskey CJ","year":"2018","unstructured":"Eskey CJ, Meyers PM, Nguyen TN,  Indications for the performance of intracranial endovascular neurointerventional procedures: a scientific statement from the American Heart Association. Circulation. 2018;137(21):e661\u2013e689. doi:10.1161\/CIR.0000000000000567"},{"issue":"9","key":"b2","series-title":"Neurology","first-page":"402","article-title":"National trends of cerebral venous sinus stenting for the treatment of idiopathic intracranial hypertension","volume":"101","author":"Khunte M","year":"2023","unstructured":"Khunte M, Chen H, Colasurdo M, Chaturvedi S, Malhotra A, Gandhi D. National trends of cerebral venous sinus stenting for the treatment of idiopathic intracranial hypertension. Neurology. 2023;101(9):402\u2013406. doi:10.1212\/WNL.0000000000207245"},{"key":"b3","series-title":"J Neurointerv Surg","article-title":"Transverse venous sinus stenting versus cerebrospinal fluid shunting in idiopathic intracranial hypertension: a multi-institutional and multinational database study","author":"Intrapiromkul J","unstructured":"Intrapiromkul J, Rai AT, Lakhani DA. Transverse venous sinus stenting versus cerebrospinal fluid shunting in idiopathic intracranial hypertension: a multi-institutional and multinational database study. J Neurointerv Surg. Published online June 27, 2025. doi:10.1136\/jnis-2025-023699"},{"key":"b4","series-title":"J Neurol Sci","first-page":"122948","article-title":"Venous sinus stenting for idiopathic intracranial hypertension: an updated meta-analysis","volume":"459","author":"Azzam AY","year":"2024","unstructured":"Azzam AY, Mortezaei A, Morsy MM,  Venous sinus stenting for idiopathic intracranial hypertension: an updated meta-analysis. 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Predicting the need for retreatment in venous sinus stenting for idiopathic intracranial hypertension. J Neurointerv Surg. 2021;13(6):574\u2013579. doi:10.1136\/neurintsurg-2020-016550"},{"key":"b7","series-title":"Headache","article-title":"Baseline factors associated with post-stenting intracranial pressure in patients with idiopathic intracranial hypertension with venous sinus stenosis","author":"Song S","unstructured":"Song S, Tu K, He J,  Baseline factors associated with post-stenting intracranial pressure in patients with idiopathic intracranial hypertension with venous sinus stenosis. Headache. Published online May 30, 2025. doi:10.1111\/head.14975"},{"issue":"10","key":"b8","series-title":"Neurology","first-page":"1492","article-title":"Diagnostic criteria for idiopathic intracranial hypertension","volume":"59","author":"Friedman DI","year":"2002","unstructured":"Friedman DI, Jacobson DM. Diagnostic criteria for idiopathic intracranial hypertension. 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J Neuroophthalmol. 2024;44(4):502\u2013506. doi:10.1097\/WNO.0000000000002055"},{"issue":"7","key":"b16","series-title":"J Neurointerv Surg","first-page":"587","article-title":"A unifying theory explaining venous sinus stenosis and recurrent stenosis following venous sinus stenting in patients with idiopathic intracranial hypertension","volume":"13","author":"Fargen KM","year":"2021","unstructured":"Fargen KM. A unifying theory explaining venous sinus stenosis and recurrent stenosis following venous sinus stenting in patients with idiopathic intracranial hypertension. 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