{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T09:04:46Z","timestamp":1780131886467,"version":"3.54.0"},"reference-count":106,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Surgery for cervical spondylotic myelopathy (CSM) aims to halt disease progression. However, some patients will also ultimately note relief from their myelopathic symptoms. This study aimed to identify factors that predict improvement from moderate or severe myelopathy to mild or no myelopathy through an analysis of preoperative clinical and demographic data. Predictive models were developed to identify patients likely to achieve durable relief from myelopathy 24 months after surgery for CSM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Data were obtained from the Quality Outcomes Database (QOD) CSM dataset, a prospective registry cohort of 1085 patients from the 14 Spine CORe\u2122 sites. Patients were excluded if they were younger than 18 years, were missing baseline or 24-month modified Japanese Orthopaedic Association scale (mJOA) scores, or had baseline mJOA score &gt; 14. The remaining patients were partitioned into a training (n = 467) or test (n = 117) set. Logistic regression and random forest models, with and without principal component analysis, were trained to predict whether patients achieved mild\/no myelopathy at 24 months, which was defined as an mJOA score of 15 or greater.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Overall, 584 patients (47.1% female) with moderate to severe myelopathy met the prespecified inclusion criteria, with a mean \u00b1 SD age of 61.7 \u00b1 11.2 years, body mass index (BMI) 30.3 \u00b1 6.3 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , and preoperative mJOA score 11.2 \u00b1 2.4. At 24 months, 45% of patients (n = 263) had mJOA score &gt; 14. There were no significant differences in performance between models with area under the receiver operating characteristic curve (AUROC) near 0.63 and area under the precision-recall curve (AUPRC) near 0.56. Significant positive predictors of postoperative relief from myelopathy in both the models and sensitivity analysis were symptom duration \u2264 12 months (OR 1.88, 95% CI 1.20\u20132.94, p &lt; 0.01) and participation in activities outside the home (OR 2.19, 95% CI 1.12\u20134.27, p = 0.02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>In a large prospective registry cohort of patients operated on for CSM, consistent factors associated with myelopathic symptom relief at 24 months were symptom duration \u2264 12 months and participation in activities outside the home. The finding that longer symptom duration was associated with a decreased propensity for relief from myelopathic symptoms suggests that earlier surgery may be beneficial for patients with moderate to severe myelopathy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2025.12.focus25932","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:31:06Z","timestamp":1777635066000},"page":"E3","source":"Crossref","is-referenced-by-count":0,"title":["Predictors of long-term myelopathy relief in patients with moderate to severe cervical spondylotic myelopathy following surgery: a Spine CORe\u2122 analysis of QOD data"],"prefix":"10.3171","volume":"60","author":[{"given":"Joshua S.","family":"Fuller","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, Columbia University Vagelos College of Physicians and Surgeons, The Och Spine Hospital at NewYork-Presbyterian, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harrison J.","family":"Howell","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Columbia University Vagelos College of Physicians and Surgeons, The Och Spine Hospital at NewYork-Presbyterian, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan J.","family":"Winans","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Columbia University Vagelos College of Physicians and Surgeons, The Och Spine Hospital at NewYork-Presbyterian, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praveen V.","family":"Mummaneni","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California, San Francisco, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dean","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Columbia University Vagelos College of Physicians and Surgeons, The Och Spine Hospital at NewYork-Presbyterian, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad","family":"Bydon","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Chicago, Illinois;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica F.","family":"Bisson","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Utah, Salt Lake City, Utah;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher I.","family":"Shaffrey","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Duke University, Durham, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oren N.","family":"Gottfried","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Duke University, Durham, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony L.","family":"Asher","sequence":"additional","affiliation":[{"name":"Neuroscience Institute, Carolinas Healthcare System and Carolina Neurosurgery & Spine Associates, Charlotte, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domagoj","family":"Coric","sequence":"additional","affiliation":[{"name":"Neuroscience Institute, Carolinas Healthcare System and Carolina Neurosurgery & Spine Associates, Charlotte, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric A.","family":"Potts","sequence":"additional","affiliation":[{"name":"Goodman Campbell Brain and Spine, Indianapolis, Indiana;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin T.","family":"Foley","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Tennessee, Semmes Murphey Neurologic and Spine Institute, Memphis, Tennessee;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Y.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Miami, Florida;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Ming","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Weill Cornell Medical Center, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Virk","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Weill Cornell Medical Center, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Knightly","sequence":"additional","affiliation":[{"name":"Atlantic Neurosurgical Specialists, Morristown, New Jersey;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott A.","family":"Meyer","sequence":"additional","affiliation":[{"name":"Atlantic Neurosurgical Specialists, Morristown, New Jersey;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Tennessee, Semmes Murphey Neurologic and Spine Institute, Memphis, Tennessee;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheerag D.","family":"Upadhyaya","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, UNC Chapel Hill, North Carolina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Po","family":"Yen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Virginia, Charlottesville, Virginia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan S.","family":"Uribe","sequence":"additional","affiliation":[{"name":"Barrow Neurological Institute, Phoenix, Arizona; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis M.","family":"Tumial\u00e1n","sequence":"additional","affiliation":[{"name":"Barrow Neurological Institute, Phoenix, Arizona; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay D.","family":"Turner","sequence":"additional","affiliation":[{"name":"Barrow Neurological Institute, Phoenix, Arizona; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regis W.","family":"Haid","sequence":"additional","affiliation":[{"name":"Atlanta Brain and Spine Care, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew K.","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Columbia University Vagelos College of Physicians and Surgeons, The Och Spine Hospital at NewYork-Presbyterian, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"4","key":"b1","series-title":"Neuroscientist","first-page":"409","article-title":"Cervical spondylotic myelopathy: the clinical phenomenon and the current pathobiology of an increasingly prevalent and devastating disorder","volume":"19","author":"Kalsi-Ryan S","year":"2013","unstructured":"Kalsi-Ryan S, Karadimas SK, Fehlings MG. 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Surg Neurol. 2009;71(1):66\u201369. doi:10.1016\/j.surneu.2008.02.045"},{"issue":"1","key":"b5","series-title":"Eur Spine J","first-page":"78","article-title":"The modified Japanese Orthopaedic Association scale: establishing criteria for mild, moderate and severe impairment in patients with degenerative cervical myelopathy","volume":"26","author":"Tetreault L","year":"2017","unstructured":"Tetreault L, Kopjar B, Nouri A,  The modified Japanese Orthopaedic Association scale: establishing criteria for mild, moderate and severe impairment in patients with degenerative cervical myelopathy. Eur Spine J. 2017;26(1):78\u201384. doi:10.1007\/s00586-016-4660-8"},{"issue":"5","key":"b6","series-title":"Spine (Phila Pa 1976)","first-page":"392","article-title":"Predictors of surgical outcome in cervical spondylotic myelopathy","volume":"38","author":"Karpova A","year":"2013","unstructured":"Karpova A, Arun R, Davis AM,  Predictors of surgical outcome in cervical spondylotic myelopathy. 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J Neurosurg Spine. 2022;37(1):41\u201348. doi:10.3171\/2021.12.SPINE21874"},{"key":"b15","series-title":"World Neurosurg","first-page":"e436","article-title":"Differences in patient-reported outcomes between anterior and posterior approaches for treatment of cervical spondylotic myelopathy: a Quality Outcomes Database analysis","volume":"160","author":"Wilkerson CG","year":"2022","unstructured":"Wilkerson CG, Sherrod BA, Alvi MA,  Differences in patient-reported outcomes between anterior and posterior approaches for treatment of cervical spondylotic myelopathy: a Quality Outcomes Database analysis. World Neurosurg. 2022;160:e436\u2013e441. doi:10.1016\/j.wneu.2022.01.049"},{"issue":"5","key":"b16","series-title":"J Neurosurg Spine","first-page":"604","article-title":"Do class III obese patients achieve similar outcomes and satisfaction to nonobese patients following surgery for cervical myelopathy? 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Clin Spine Surg. 2024;37(3):E137\u2013E146. doi:10.1097\/BSD.0000000000001557"},{"issue":"1","key":"b26","series-title":"Neurosurg Focus","first-page":"E4","article-title":"Defining cervical spondylotic myelopathy surgical endotypes using comorbidity clustering: a Quality Outcomes Database cervical spondylotic myelopathy study","volume":"59","author":"Yang E","year":"2025","unstructured":"Yang E, Howell H, Mummaneni PV,  Defining cervical spondylotic myelopathy surgical endotypes using comorbidity clustering: a Quality Outcomes Database cervical spondylotic myelopathy study. Neurosurg Focus. 2025;59(1):E4. doi:10.3171\/2025.4.FOCUS25207"},{"issue":"3","key":"b27","series-title":"J Stat Soft","first-page":"1","article-title":"mice: Multivariate Imputation by Chained Equations in R","volume":"45","author":"Buuren SV","year":"2011","unstructured":"Buuren SV, Groothuis-Oudshoorn K. mice: Multivariate Imputation by Chained Equations in R. 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BMC Med Inform Decis Mak. 2022;22(1):270. doi:10.1186\/s12911-022-02016-z"},{"issue":"2","key":"b30","series-title":"J Stat Soft","first-page":"1","article-title":"carat: an R Package for Covariate-Adaptive Randomization in Clinical Trials","volume":"107","author":"Ma W","year":"2023","unstructured":"Ma W, Ye X, Tu F, Hu F. carat: an R Package for Covariate-Adaptive Randomization in Clinical Trials. J Stat Soft. 2023;107(2):1\u201347. doi:10.18637\/jss.v107.i02"},{"key":"b31","article-title":"fastDummies: fast creation of dummy (binary) columns and rows from categorical variables. R package version 1.7.4","author":"Kaplan J","unstructured":"Kaplan J. fastDummies: fast creation of dummy (binary) columns and rows from categorical variables. R package version 1.7.4. 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