{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:43:15Z","timestamp":1785422595816,"version":"3.56.0"},"reference-count":64,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>The concept of hybrid therapy as separation surgery, followed by stereotactic radiation therapy or stereotactic body radiation therapy, is becoming the new standard of care in the management of metastatic epidural spinal cord compressions (MESCCs). Nevertheless, this new concept remains a form of palliative treatment, and surgical efforts to minimize morbidity and prolong survival serve to maximize palliation. Such strategies include short-segment fixation with cement augmentation, described as 1 level above and below the index level of the MESCC (single vertebral body level). The use of carbon fiber\u2013reinforced polyetheretherketone (CFRP) instrumentation has allowed precise contouring in radiation planning and earlier detection of tumor recurrence, while being biomechanically comparable to standard titanium instrumentation. Therefore, the authors wanted to explore the feasibility of short-segment cement-augmented CFRP instrumentation for patients with spinal metastasis requiring separation surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A retrospective review was conducted from April 2022 to May 2024. Inclusion criteria were as follows: 1) patients who had open separation surgery for MESCC, 2) with short-segment cement-augmented CFRP instrumentation (defined as 1 level above and below the index disease level), 3) who underwent postoperative radiation therapy, with 4) a minimum 6 months of survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Twenty-eight patients met the inclusion criteria. The mean survival was 14.9 months, mean radiographic follow-up was 7.9 months, median estimated blood loss was 300 ml, and mean operative time was 214 minutes. There were no cement- or hardware-related complications. There were 3 cases of postoperative kyphosis, one of which was symptomatic, but all were managed nonoperatively. One patient required a reoperation for repair of a CSF leak.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Short-segment cement-augmented fixation is a feasible strategy in open separation surgery for MESCC. This is the first clinical study to incorporate the use of CFRP instrumentation in such a surgical strategy. Additional studies with larger sample sizes and longer durations of follow-up would support both the durability and potential survival benefit over titanium instrumentation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2025.2.focus24994","type":"journal-article","created":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T06:39:44Z","timestamp":1746081584000},"page":"E9","source":"Crossref","is-referenced-by-count":5,"title":["Separation surgery with cement-augmented short-segment fixation for spinal metastasis: early experience with carbon fiber\u2013reinforced polyetheretherketone instrumentation"],"prefix":"10.3171","volume":"58","author":[{"given":"Anas","family":"Bardeesi","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, The Ohio State University Wexner Medical Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth","family":"Wilson","sequence":"additional","affiliation":[{"name":"The Ohio State University College of Medicine; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Ward","sequence":"additional","affiliation":[{"name":"The Ohio State University College of Medicine; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Damante","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The Ohio State University Wexner Medical Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua D.","family":"Palmer","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, The James Cancer Hospital at The Ohio State University Wexner Medical Center, Columbus, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The Ohio State University Wexner Medical Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Bradley","family":"Elder","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The Ohio State University Wexner Medical Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikram B.","family":"Chakravarthy","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The Ohio State University Wexner Medical Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"4","key":"b1","series-title":"Neurol Clin","first-page":"825","article-title":"Metastatic epidural spinal cord compression","volume":"9","author":"Grant R","year":"1991","unstructured":"Grant R, Papadopoulos SM, Greenberg HS. Metastatic epidural spinal cord compression. Neurol Clin. 1991;9(4):825\u2013841."},{"issue":"5","key":"b2","series-title":"Lancet Neurol","first-page":"459","article-title":"Metastatic epidural spinal cord compression","volume":"7","author":"Cole JS","year":"2008","unstructured":"Cole JS, Patchell RA. Metastatic epidural spinal cord compression. Lancet Neurol. 2008;7(5):459\u2013466."},{"issue":"11","key":"b3","series-title":"Ann Transl Med","first-page":"386","article-title":"Narrative review-diagnosing and managing malignant epidural spinal cord compression: an evidence-based approach","volume":"11","author":"Akanda ZZ","year":"2023","unstructured":"Akanda ZZ, McKay MJ. Narrative review-diagnosing and managing malignant epidural spinal cord compression: an evidence-based approach. Ann Transl Med. 2023;11(11):386."},{"issue":"8","key":"b4","series-title":"J Bone Joint Surg Br","first-page":"1054","article-title":"The surgical management of metastatic epidural compression of the spinal cord","volume":"92","author":"Quraishi NA","year":"2010","unstructured":"Quraishi NA, Gokaslan ZL, Boriani S. The surgical management of metastatic epidural compression of the spinal cord. J Bone Joint Surg Br. 2010;92(8):1054\u20131060."},{"issue":"11","key":"b5","series-title":"Eur Spine J","first-page":"1970","article-title":"Surgery improves pain, function and quality of life in patients with spinal metastases: a prospective study on 118 patients","volume":"20","author":"Quan GM","year":"2011","unstructured":"Quan GM, Vital JM, Aurouer N,  Surgery improves pain, function and quality of life in patients with spinal metastases: a prospective study on 118 patients. Eur Spine J. 2011;20(11):1970\u20131978."},{"issue":"10","key":"b6","series-title":"Nat Rev Clin Oncol","first-page":"590","article-title":"The role of radiotherapy for metastatic epidural spinal cord compression","volume":"7","author":"Rades D","year":"2010","unstructured":"Rades D, Abrahm JL. The role of radiotherapy for metastatic epidural spinal cord compression. Nat Rev Clin Oncol. 2010;7(10):590\u2013598."},{"issue":"3","key":"b7","series-title":"J Neurosurg Spine","first-page":"207","article-title":"Local disease control for spinal metastases following \"separation surgery\" and adjuvant hypofractionated or high-dose single-fraction stereotactic radiosurgery: outcome analysis in 186 patients","volume":"18","author":"Laufer I","year":"2013","unstructured":"Laufer I, Iorgulescu JB, Chapman T,  Local disease control for spinal metastases following \"separation surgery\" and adjuvant hypofractionated or high-dose single-fraction stereotactic radiosurgery: outcome analysis in 186 patients. J Neurosurg Spine. 2013;18(3):207\u2013214."},{"issue":"4","key":"b8","series-title":"J Neurosurg Spine","first-page":"409","article-title":"Stereotactic radiosurgery for spinal metastases with or without separation surgery","volume":"22","author":"Bate BG","year":"2015","unstructured":"Bate BG, Khan NR, Kimball BY, Gabrick K, Weaver J. Stereotactic radiosurgery for spinal metastases with or without separation surgery. J Neurosurg Spine. 2015;22(4):409\u2013415."},{"issue":"2","key":"b9","series-title":"Neurosurg Clin N Am","first-page":"191","article-title":"Hybrid therapy for spinal metastases","volume":"31","author":"Rothrock R","year":"2020","unstructured":"Rothrock R, Pennington Z, Ehresman J,  Hybrid therapy for spinal metastases. Neurosurg Clin N Am. 2020;31(2):191\u2013200."},{"issue":"3","key":"b10","series-title":"Oper Neurosurg (Hagerstown)","first-page":"310","article-title":"Hybrid therapy for metastatic epidural spinal cord compression: technique for separation surgery and spine radiosurgery","volume":"16","author":"Barzilai O","year":"2019","unstructured":"Barzilai O, Laufer I, Robin A, Xu R, Yamada Y, Bilsky MH. Hybrid therapy for metastatic epidural spinal cord compression: technique for separation surgery and spine radiosurgery. Oper Neurosurg (Hagerstown). 2019;16(3):310\u2013318."},{"key":"b11","series-title":"J Bone Oncol","first-page":"100320","article-title":"Separation surgery for metastatic epidural spinal cord compression: a qualitative review","volume":"25","author":"Di Perna G","year":"2020","unstructured":"Di Perna G, Cofano F, Mantovani C,  Separation surgery for metastatic epidural spinal cord compression: a qualitative review. J Bone Oncol. 2020;25:100320."},{"key":"b12","series-title":"J Oncol","first-page":"7904740","article-title":"Treatment of spinal metastases with epidural cord compression through corpectomy and reconstruction via the traditional open approach versus the mini-open approach: a multicenter retrospective study","volume":"2019","author":"Zhou X","year":"2019","unstructured":"Zhou X, Cui H, He Y, Qiu G, Zhou D, Liu Y. Treatment of spinal metastases with epidural cord compression through corpectomy and reconstruction via the traditional open approach versus the mini-open approach: a multicenter retrospective study. J Oncol. 2019;2019:7904740."},{"issue":"2","key":"b13","series-title":"Neurosurg Focus Video","first-page":"V11","article-title":"MIS technique for separation surgery in lumbar spine metastatic disease","volume":"10","author":"Martins Coelho Junior VP","year":"2024","unstructured":"Martins Coelho Junior VP, Dhaliwal JS, Chakravarthy VB. MIS technique for separation surgery in lumbar spine metastatic disease. Neurosurg Focus Video. 2024;10(2):V11."},{"issue":"6","key":"b14","series-title":"Oper Neurosurg (Hagerstown)","first-page":"606","article-title":"Minimally invasive separation surgery for metastases in the vertebral column: a technical report","volume":"18","author":"Vega RA","year":"2020","unstructured":"Vega RA, Traylor JI, Habib A, Rhines LD, Tatsui CE, Rao G. Minimally invasive separation surgery for metastases in the vertebral column: a technical report. Oper Neurosurg (Hagerstown). 2020;18(6):606\u2013613."},{"issue":"19","key":"b15","series-title":"Spine (Phila Pa 1976)","first-page":"E1126","article-title":"Short limited fusion versus long fusion with deformity correction for spinal stenosis with balanced de novo degenerative lumbar scoliosis: a meta-analysis of direct comparative studies","volume":"42","author":"Lee CH","year":"2017","unstructured":"Lee CH, Chung CK, Sohn MJ, Kim CH. Short limited fusion versus long fusion with deformity correction for spinal stenosis with balanced de novo degenerative lumbar scoliosis: a meta-analysis of direct comparative studies. Spine (Phila Pa 1976). 2017;42(19):E1126\u2013E1132."},{"key":"b16","series-title":"World Neurosurg","first-page":"e611","article-title":"Short-segment versus long-segment spinal fusion constructs for the treatment of adult degenerative scoliosis: a comparison of clinical outcomes","volume":"171","author":"Ledesma JA","year":"2023","unstructured":"Ledesma JA, Tran K, Lambrechts MJ,  Short-segment versus long-segment spinal fusion constructs for the treatment of adult degenerative scoliosis: a comparison of clinical outcomes. World Neurosurg. 2023;171:e611\u2013e619."},{"issue":"2","key":"b17","series-title":"J Korean Neurosurg Soc","first-page":"189","article-title":"Bone cement-augmented percutaneous screw fixation for malignant spinal metastases: is it feasible?","volume":"60","author":"Kim P","year":"2017","unstructured":"Kim P, Kim SW. Bone cement-augmented percutaneous screw fixation for malignant spinal metastases: is it feasible?. J Korean Neurosurg Soc. 2017;60(2):189\u2013194."},{"issue":"7","key":"b18","series-title":"Spine J","first-page":"1609","article-title":"Short-segment percutaneous pedicle screw fixation with cement augmentation for tumor-induced spinal instability","volume":"15","author":"Moussazadeh N","year":"2015","unstructured":"Moussazadeh N, Rubin DG, McLaughlin L, Lis E, Bilsky MH, Laufer I. Short-segment percutaneous pedicle screw fixation with cement augmentation for tumor-induced spinal instability. Spine J. 2015;15(7):1609\u20131617."},{"issue":"5","key":"b19","series-title":"Oper Neurosurg (Hagerstown)","first-page":"593","article-title":"Utility of cement augmentation via percutaneous fenestrated pedicle screws for stabilization of cancer-related spinal instability","volume":"16","author":"Barzilai O","year":"2019","unstructured":"Barzilai O, McLaughlin L, Lis E, Reiner AS, Bilsky MH, Laufer I. Utility of cement augmentation via percutaneous fenestrated pedicle screws for stabilization of cancer-related spinal instability. Oper Neurosurg (Hagerstown). 2019;16(5):593\u2013599."},{"issue":"5","key":"b20","series-title":"Neurosurg Focus","first-page":"E11","article-title":"Short-segment cement-augmented fixation in open separation surgery of metastatic epidural spinal cord compression: initial experience","volume":"50","author":"Newman WC","year":"2021","unstructured":"Newman WC, Amin AG, Villavieja J, Laufer I, Bilsky MH, Barzilai O. Short-segment cement-augmented fixation in open separation surgery of metastatic epidural spinal cord compression: initial experience. Neurosurg Focus. 2021;50(5):E11."},{"issue":"9","key":"b21","series-title":"Spine J","first-page":"1850","article-title":"The incidence and patterns of hardware failure after separation surgery in patients with spinal metastatic tumors","volume":"14","author":"Amankulor NM","year":"2014","unstructured":"Amankulor NM, Xu R, Iorgulescu JB,  The incidence and patterns of hardware failure after separation surgery in patients with spinal metastatic tumors. Spine J. 2014;14(9):1850\u20131859."},{"issue":"2","key":"b22","series-title":"Adv Radiother Nucl Med","first-page":"3130","article-title":"Emerging role of carbon fiber-reinforced polyetheretherketone instrumentation in spinal oncology: a systematic review","volume":"2","author":"Ward J","year":"2024","unstructured":"Ward J, Wilson S, Eaton RG, Coelho V, Xu DS, Chakravarthy VB. Emerging role of carbon fiber-reinforced polyetheretherketone instrumentation in spinal oncology: a systematic review. Adv Radiother Nucl Med. 2024;2(2):3130."},{"key":"b23","series-title":"World Neurosurg","first-page":"294","article-title":"Radiolucent carbon fiber-reinforced pedicle screws for treatment of spinal tumors: advantages for radiation planning and follow-up imaging","volume":"105","author":"Ringel F","year":"2017","unstructured":"Ringel F, Ryang YM, Kirschke JS,  Radiolucent carbon fiber-reinforced pedicle screws for treatment of spinal tumors: advantages for radiation planning and follow-up imaging. World Neurosurg. 2017;105:294\u2013301."},{"issue":"1","key":"b24","series-title":"titanium. J Neurooncol","first-page":"155","article-title":"Impact of instrumentation material on local recurrence: a case-matched series using carbon fiber-PEEK vs","volume":"171","author":"Ward J","year":"2025","unstructured":"Ward J, Damante M, Wilson S,  Impact of instrumentation material on local recurrence: a case-matched series using carbon fiber-PEEK vs. titanium. J Neurooncol. 2025;171(1):155\u2013162."},{"issue":"6","key":"b25","series-title":"Neurosurgery","first-page":"1354","article-title":"Treatment of thoracolumbar burst fractures with polymethyl methacrylate vertebroplasty and short-segment pedicle screw fixation","volume":"53","author":"Cho DY","year":"2003","unstructured":"Cho DY, Lee WY, Sheu PC. Treatment of thoracolumbar burst fractures with polymethyl methacrylate vertebroplasty and short-segment pedicle screw fixation. Neurosurgery. 2003;53(6):1354\u20131361."},{"issue":"1","key":"b26","series-title":"BMC Musculoskelet Disord","first-page":"203","article-title":"Hybrid kyphoplasty with short-versus intermediate- and long-segment pedicle screw fixations for the management of thoracolumbar burst fractures","volume":"25","author":"Chou KN","year":"2024","unstructured":"Chou KN, Wang PW, Chung MH, Ju DT. Hybrid kyphoplasty with short-versus intermediate- and long-segment pedicle screw fixations for the management of thoracolumbar burst fractures. BMC Musculoskelet Disord. 2024;25(1):203."},{"issue":"3","key":"b27","series-title":"J Neurooncol","first-page":"705","article-title":"Early versus late construct failure in spine metastatic disease: implications for surgical strategy and oncologic outcome","volume":"171","author":"Kreatsoulas D","year":"2025","unstructured":"Kreatsoulas D, George A, Kolawole S,  Early versus late construct failure in spine metastatic disease: implications for surgical strategy and oncologic outcome. J Neurooncol. 2025;171(3):705\u2013714."},{"issue":"21","key":"b28","series-title":"Cancers (Basel)","first-page":"5275","article-title":"CFR-PEEK Pedicle screw instrumentation for spinal neoplasms: a single center experience on safety and efficacy","volume":"14","author":"Joerger AK","year":"2022","unstructured":"Joerger AK, Seitz S, Lange N,  CFR-PEEK Pedicle screw instrumentation for spinal neoplasms: a single center experience on safety and efficacy. Cancers (Basel). 2022;14(21):5275."},{"issue":"2","key":"b29","series-title":"J Spinal Disord Tech","first-page":"E28","article-title":"Polymethylmethacrylate augmentation of pedicle screws increases the initial fixation in osteoporotic spine patients","volume":"25","author":"Sawakami K","year":"2012","unstructured":"Sawakami K, Yamazaki A, Ishikawa S, Ito T, Watanabe K, Endo N. Polymethylmethacrylate augmentation of pedicle screws increases the initial fixation in osteoporotic spine patients. J Spinal Disord Tech. 2012;25(2):E28\u2013E35."},{"issue":"6","key":"b30","series-title":"J Spinal Disord Tech","first-page":"305","article-title":"Polymethylmethacrylate augmentation of cannulated pedicle screws for fixation in osteoporotic spines and comparison of its clinical results and biomechanical characteristics with the needle injection method","volume":"26","author":"Chang MC","year":"2013","unstructured":"Chang MC, Kao HC, Ying SH, Liu CL. Polymethylmethacrylate augmentation of cannulated pedicle screws for fixation in osteoporotic spines and comparison of its clinical results and biomechanical characteristics with the needle injection method. J Spinal Disord Tech. 2013;26(6):305\u2013315."},{"key":"b31","series-title":"World Neurosurg","first-page":"61","article-title":"Radiolucent carbon fiber-reinforced implants for treatment of spinal tumors-clinical, radiographic, and dosimetric considerations","volume":"152","author":"Takayanagi A","year":"2021","unstructured":"Takayanagi A, Siddiqi I, Ghanchi H,  Radiolucent carbon fiber-reinforced implants for treatment of spinal tumors-clinical, radiographic, and dosimetric considerations. World Neurosurg. 2021;152:61\u201370."},{"key":"b32","series-title":"J Clin Neurosci","first-page":"106","article-title":"Carbon fiber reinforced vs titanium implants for fixation in spinal metastases: a comparative clinical study about safety and effectiveness of the new \"carbon-strategy.\"","volume":"75","author":"Cofano F","year":"2020","unstructured":"Cofano F, Di Perna G, Monticelli M,  Carbon fiber reinforced vs titanium implants for fixation in spinal metastases: a comparative clinical study about safety and effectiveness of the new \"carbon-strategy.\". J Clin Neurosci. 2020;75:106\u2013111."},{"issue":"4","key":"b1","series-title":"Neurol Clin","first-page":"825","article-title":"Metastatic epidural spinal cord compression","volume":"9","author":"Grant R","year":"1991","unstructured":"Grant R, Papadopoulos SM, Greenberg HS. Metastatic epidural spinal cord compression. Neurol Clin. 1991;9(4):825\u2013841."},{"issue":"5","key":"b2","series-title":"Lancet Neurol","first-page":"459","article-title":"Metastatic epidural spinal cord compression","volume":"7","author":"Cole JS","year":"2008","unstructured":"Cole JS, Patchell RA. Metastatic epidural spinal cord compression. Lancet Neurol. 2008;7(5):459\u2013466."},{"issue":"11","key":"b3","series-title":"Ann Transl Med","first-page":"386","article-title":"Narrative review-diagnosing and managing malignant epidural spinal cord compression: an evidence-based approach","volume":"11","author":"Akanda ZZ","year":"2023","unstructured":"Akanda ZZ, McKay MJ. Narrative review-diagnosing and managing malignant epidural spinal cord compression: an evidence-based approach. Ann Transl Med. 2023;11(11):386."},{"issue":"8","key":"b4","series-title":"J Bone Joint Surg Br","first-page":"1054","article-title":"The surgical management of metastatic epidural compression of the spinal cord","volume":"92","author":"Quraishi NA","year":"2010","unstructured":"Quraishi NA, Gokaslan ZL, Boriani S. The surgical management of metastatic epidural compression of the spinal cord. J Bone Joint Surg Br. 2010;92(8):1054\u20131060."},{"issue":"11","key":"b5","series-title":"Eur Spine J","first-page":"1970","article-title":"Surgery improves pain, function and quality of life in patients with spinal metastases: a prospective study on 118 patients","volume":"20","author":"Quan GM","year":"2011","unstructured":"Quan GM, Vital JM, Aurouer N,  Surgery improves pain, function and quality of life in patients with spinal metastases: a prospective study on 118 patients. Eur Spine J. 2011;20(11):1970\u20131978."},{"issue":"10","key":"b6","series-title":"Nat Rev Clin Oncol","first-page":"590","article-title":"The role of radiotherapy for metastatic epidural spinal cord compression","volume":"7","author":"Rades D","year":"2010","unstructured":"Rades D, Abrahm JL. The role of radiotherapy for metastatic epidural spinal cord compression. Nat Rev Clin Oncol. 2010;7(10):590\u2013598."},{"issue":"3","key":"b7","series-title":"J Neurosurg Spine","first-page":"207","article-title":"Local disease control for spinal metastases following \"separation surgery\" and adjuvant hypofractionated or high-dose single-fraction stereotactic radiosurgery: outcome analysis in 186 patients","volume":"18","author":"Laufer I","year":"2013","unstructured":"Laufer I, Iorgulescu JB, Chapman T,  Local disease control for spinal metastases following \"separation surgery\" and adjuvant hypofractionated or high-dose single-fraction stereotactic radiosurgery: outcome analysis in 186 patients. J Neurosurg Spine. 2013;18(3):207\u2013214."},{"issue":"4","key":"b8","series-title":"J Neurosurg Spine","first-page":"409","article-title":"Stereotactic radiosurgery for spinal metastases with or without separation surgery","volume":"22","author":"Bate BG","year":"2015","unstructured":"Bate BG, Khan NR, Kimball BY, Gabrick K, Weaver J. Stereotactic radiosurgery for spinal metastases with or without separation surgery. J Neurosurg Spine. 2015;22(4):409\u2013415."},{"issue":"2","key":"b9","series-title":"Neurosurg Clin N Am","first-page":"191","article-title":"Hybrid therapy for spinal metastases","volume":"31","author":"Rothrock R","year":"2020","unstructured":"Rothrock R, Pennington Z, Ehresman J,  Hybrid therapy for spinal metastases. Neurosurg Clin N Am. 2020;31(2):191\u2013200."},{"issue":"3","key":"b10","series-title":"Oper Neurosurg (Hagerstown)","first-page":"310","article-title":"Hybrid therapy for metastatic epidural spinal cord compression: technique for separation surgery and spine radiosurgery","volume":"16","author":"Barzilai O","year":"2019","unstructured":"Barzilai O, Laufer I, Robin A, Xu R, Yamada Y, Bilsky MH. Hybrid therapy for metastatic epidural spinal cord compression: technique for separation surgery and spine radiosurgery. 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Treatment of spinal metastases with epidural cord compression through corpectomy and reconstruction via the traditional open approach versus the mini-open approach: a multicenter retrospective study. J Oncol. 2019;2019:7904740."},{"issue":"2","key":"b13","series-title":"Neurosurg Focus Video","first-page":"V11","article-title":"MIS technique for separation surgery in lumbar spine metastatic disease","volume":"10","author":"Martins Coelho Junior VP","year":"2024","unstructured":"Martins Coelho Junior VP, Dhaliwal JS, Chakravarthy VB. MIS technique for separation surgery in lumbar spine metastatic disease. Neurosurg Focus Video. 2024;10(2):V11."},{"issue":"6","key":"b14","series-title":"Oper Neurosurg (Hagerstown)","first-page":"606","article-title":"Minimally invasive separation surgery for metastases in the vertebral column: a technical report","volume":"18","author":"Vega RA","year":"2020","unstructured":"Vega RA, Traylor JI, Habib A, Rhines LD, Tatsui CE, Rao G. Minimally invasive separation surgery for metastases in the vertebral column: a technical report. Oper Neurosurg (Hagerstown). 2020;18(6):606\u2013613."},{"issue":"19","key":"b15","series-title":"Spine (Phila Pa 1976)","first-page":"E1126","article-title":"Short limited fusion versus long fusion with deformity correction for spinal stenosis with balanced de novo degenerative lumbar scoliosis: a meta-analysis of direct comparative studies","volume":"42","author":"Lee CH","year":"2017","unstructured":"Lee CH, Chung CK, Sohn MJ, Kim CH. Short limited fusion versus long fusion with deformity correction for spinal stenosis with balanced de novo degenerative lumbar scoliosis: a meta-analysis of direct comparative studies. Spine (Phila Pa 1976). 2017;42(19):E1126\u2013E1132."},{"key":"b16","series-title":"World Neurosurg","first-page":"e611","article-title":"Short-segment versus long-segment spinal fusion constructs for the treatment of adult degenerative scoliosis: a comparison of clinical outcomes","volume":"171","author":"Ledesma JA","year":"2023","unstructured":"Ledesma JA, Tran K, Lambrechts MJ,  Short-segment versus long-segment spinal fusion constructs for the treatment of adult degenerative scoliosis: a comparison of clinical outcomes. World Neurosurg. 2023;171:e611\u2013e619."},{"issue":"2","key":"b17","series-title":"J Korean Neurosurg Soc","first-page":"189","article-title":"Bone cement-augmented percutaneous screw fixation for malignant spinal metastases: is it feasible?","volume":"60","author":"Kim P","year":"2017","unstructured":"Kim P, Kim SW. Bone cement-augmented percutaneous screw fixation for malignant spinal metastases: is it feasible?. 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Utility of cement augmentation via percutaneous fenestrated pedicle screws for stabilization of cancer-related spinal instability. Oper Neurosurg (Hagerstown). 2019;16(5):593\u2013599."},{"issue":"5","key":"b20","series-title":"Neurosurg Focus","first-page":"E11","article-title":"Short-segment cement-augmented fixation in open separation surgery of metastatic epidural spinal cord compression: initial experience","volume":"50","author":"Newman WC","year":"2021","unstructured":"Newman WC, Amin AG, Villavieja J, Laufer I, Bilsky MH, Barzilai O. Short-segment cement-augmented fixation in open separation surgery of metastatic epidural spinal cord compression: initial experience. 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