{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:58:22Z","timestamp":1782176302102,"version":"3.54.5"},"reference-count":72,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>The aim of this study was to compare intra- and perioperative outcomes, complications, and magnitude of curve correction among patients with adolescent idiopathic scoliosis (AIS; 10\u201318 years old) and young adult idiopathic scoliosis (YAdIS; 19\u201340 years old).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A retrospective review of AIS and YAdIS patients who underwent primary corrective surgery at a single center was conducted. Demographic, radiographic, and operative data were collected at the pre- and perioperative periods. A 1:1 propensity score\u2013matched analysis was implemented to limit selection bias by controlling for gender, curve type, total instrumented levels, and main coronal Cobb angle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Two hundred thirty-six patients (144 with AIS, 92 with YAdIS) were identified. Following propensity score matching, 85 matched pairs were identified. Radiographically, AIS had greater flexible main thoracic (mean \u221223.7% \u00b1 14.1% vs \u221218.4% \u00b1 11.0%, p = 0.0155) and thoracolumbar\/lumbar curves (mean \u221232.0% \u00b1 16.6% vs \u201328.5% \u00b1 20.6%, p = 0.0229) preoperatively. The AIS group had a shorter operating room (OR) duration (mean 4.8 \u00b1 1.3 vs 5.3 \u00b1 1.5 hours, p = 0.0088), estimated blood loss (EBL; mean 654.7 \u00b1 330.7 vs 806.7 \u00b1 446.8 ml, p = 0.0092), and intraoperative transfusion rates (83.5% vs 96.5%, p = 0.0045). Postoperatively, the AIS patients had a lower rate of overall complications (9.4% vs 16.5%, p = 0.0412) and a lower transfusion rate (24.7% vs 40.0%, p = 0.0236). No differences in type of complication and hospital length of stay were observed (p &gt; 0.05). AIS patients had smaller mean T10\u201312 thoracic kyphosis (TK; 6.3\u00b0 \u00b1 4.8\u00b0 vs 9.0\u00b0 \u00b1 6.5\u00b0, p = 0.0242) and T1 pelvic angle (8.7\u00b0 \u00b1 8.2\u00b0 vs 11.5\u00b0 \u00b1 8.7\u00b0, p = 0.048) postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Patients with idiopathic scoliosis who undergo corrective surgery as adolescents had more flexible curves with shorter OR times, less EBL, and lower perioperative complication rates than young adults. Radiographic correction of the major coronal curve and of thoracic sagittal kyphosis was similar for both groups. Overall, AIS and YAdIS patients can expect generally successful operative outcomes and low complication rates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2025.3.spine241454","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T14:34:45Z","timestamp":1757687685000},"page":"443-452","source":"Crossref","is-referenced-by-count":2,"title":["Perioperative outcomes in adolescent versus young adult patients with idiopathic scoliosis: how different are they?"],"prefix":"10.3171","volume":"43","author":[{"given":"Alexandra C.","family":"Dionne","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Columbia University Irving Medical Center, New York;"},{"name":"Vagelos College of Physicians and Surgeons, Columbia University, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence G.","family":"Lenke","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Columbia University Irving Medical Center, New York;"},{"name":"The Och Spine Hospital, NewYork-Presbyterian, New York, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fthimnir M.","family":"Hassan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Columbia University Irving Medical Center, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin L.","family":"Reyes","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Columbia University Irving Medical Center, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chidebelum","family":"Nnake","sequence":"additional","affiliation":[{"name":"Vagelos College of Physicians and Surgeons, Columbia University, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Blanchard","sequence":"additional","affiliation":[{"name":"Vagelos College of Physicians and Surgeons, Columbia University, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Columbia University Irving Medical Center, New York;"},{"name":"New York Medical College, Touro University, Valhalla, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M.","family":"Lombardi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Columbia University Irving Medical Center, New York;"},{"name":"The Och Spine Hospital, NewYork-Presbyterian, New York, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeeshan M.","family":"Sardar","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Columbia University Irving Medical Center, New York;"},{"name":"The Och Spine Hospital, NewYork-Presbyterian, New York, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"2","key":"b1","series-title":"JAMA","first-page":"165","article-title":"Screening for adolescent idiopathic scoliosis: US Preventive Services Task Force recommendation statement","volume":"319","author":"Grossman DC","year":"2018","unstructured":"Grossman DC, Curry SJ, Owens DK,  Screening for adolescent idiopathic scoliosis: US Preventive Services Task Force recommendation statement. JAMA. 2018;319(2):165\u2013172."},{"key":"b2","series-title":"Preventive Services Task Force","article-title":"Screening for adolescent idiopathic scoliosis: a systematic evidence review for the U.S","author":"Dunn J","year":"2018","unstructured":"Dunn J, Henrikson NB, Morrison CC, Nguyen M, Blasi PR, Lin JS. Screening for adolescent idiopathic scoliosis: a systematic evidence review for the U.S. Preventive Services Task Force. 2018.Accessed April 28, 2025. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK493367\/"},{"issue":"1","key":"b3","series-title":"J Child Orthop","first-page":"3","article-title":"Epidemiology of adolescent idiopathic scoliosis","volume":"7","author":"Konieczny MR","year":"2013","unstructured":"Konieczny MR, Senyurt H, Krauspe R. Epidemiology of adolescent idiopathic scoliosis. J Child Orthop. 2013;7(1):3\u20139."},{"issue":"3","key":"b4","series-title":"Spine Deform","first-page":"643","article-title":"Outcomes for nighttime bracing in adolescent idiopathic scoliosis based on brace wear adherence","volume":"12","author":"Zapata KA","year":"2024","unstructured":"Zapata KA, Virostek D, Ma Y,  Outcomes for nighttime bracing in adolescent idiopathic scoliosis based on brace wear adherence. Spine Deform. 2024;12(3):643\u2013650."},{"key":"b5","series-title":"Physiotherapy","first-page":"46","article-title":"The effects of physiotherapeutic scoliosis-specific exercise on idiopathic scoliosis in children and adolescents: a systematic review and meta-analysis","volume":"121","author":"Ma K","year":"2023","unstructured":"Ma K, Wang C, Huang Y, Wang Y, Li D, He G. The effects of physiotherapeutic scoliosis-specific exercise on idiopathic scoliosis in children and adolescents: a systematic review and meta-analysis. Physiotherapy. 2023;121:46\u201357."},{"key":"b6","series-title":"Scoliosis","first-page":"6","article-title":"Surgical treatment of scoliosis: a review of techniques currently applied","volume":"3","author":"Maruyama T","year":"2008","unstructured":"Maruyama T, Takeshita K. Surgical treatment of scoliosis: a review of techniques currently applied. Scoliosis. 2008;3:6."},{"issue":"1","key":"b7","series-title":"Patient Saf Surg","first-page":"25","article-title":"Adolescent idiopathic scoliosis \u2013 to operate or not? A debate article","volume":"2","author":"Weiss HR","year":"2008","unstructured":"Weiss HR, Bess S, Wong MS, Patel V, Goodall D, Burger E. Adolescent idiopathic scoliosis \u2013 to operate or not? A debate article. Patient Saf Surg. 2008;2(1):25."},{"issue":"5","key":"b8","series-title":"Spine Deform","first-page":"1133","article-title":"Comparison of operative implications between adolescent and young adult idiopathic scoliosis patients from scoliosis research society mortality and morbidity database","volume":"10","author":"Kurra S","year":"2022","unstructured":"Kurra S, DeMercurio P, Lavelle WF. Comparison of operative implications between adolescent and young adult idiopathic scoliosis patients from scoliosis research society mortality and morbidity database. Spine Deform. 2022;10(5):1133\u20131138."},{"issue":"1","key":"b9","series-title":"Global Spine J","first-page":"81","article-title":"A comparison between the perioperative outcomes of female Adolescent Idiopathic Scoliosis (AIS) versus Adult Idiopathic Scoliosis (AdIS) following posterior spinal fusion: a propensity score matching analysis involving 425 patients","volume":"13","author":"Chan CYW","year":"2023","unstructured":"Chan CYW, Gani SMA, Chung WH, Chiu CK, Hasan MS, Kwan MK. A comparison between the perioperative outcomes of female Adolescent Idiopathic Scoliosis (AIS) versus Adult Idiopathic Scoliosis (AdIS) following posterior spinal fusion: a propensity score matching analysis involving 425 patients. Global Spine J. 2023;13(1):81\u201388."},{"issue":"5","key":"b10","series-title":"Cureus","first-page":"e8118","article-title":"Clinical outcomes of idiopathic scoliosis surgery: is there a difference between young adult patients and adolescent patients?","volume":"12","author":"Lavelle W","year":"2020","unstructured":"Lavelle W, Kurra S, Hu X, Lieberman I. Clinical outcomes of idiopathic scoliosis surgery: is there a difference between young adult patients and adolescent patients?. Cureus. 2020;12(5):e8118."},{"issue":"6","key":"b11","series-title":"Spine Deform","first-page":"1443","article-title":"Clinical and radiographic outcomes following correction of idiopathic scoliosis in adolescence vs young adulthood","volume":"11","author":"LaBarge ME","year":"2023","unstructured":"LaBarge ME, Chanbour H, Waddell WH,  Clinical and radiographic outcomes following correction of idiopathic scoliosis in adolescence vs young adulthood. Spine Deform. 2023;11(6):1443\u20131451."},{"issue":"7","key":"b12","series-title":"Eur Spine J","first-page":"2541","article-title":"Clinical differences in preoperative symptoms and surgical outcomes between early and late-teen patients with Lenke type 5C adolescent idiopathic scoliosis","volume":"32","author":"Banno T","year":"2023","unstructured":"Banno T, Yamato Y, Oba H,  Clinical differences in preoperative symptoms and surgical outcomes between early and late-teen patients with Lenke type 5C adolescent idiopathic scoliosis. Eur Spine J. 2023;32(7):2541\u20132549."},{"issue":"3","key":"b13","series-title":"Spine Deform","first-page":"665","article-title":"Posterior-only correction surgery for idiopathic scoliosis Lenke type 5c: differences of strategies and outcomes between adult patients and adolescent patients","volume":"11","author":"Pan X","year":"2023","unstructured":"Pan X, Qiao J, Liu Z,  Posterior-only correction surgery for idiopathic scoliosis Lenke type 5c: differences of strategies and outcomes between adult patients and adolescent patients. Spine Deform. 2023;11(3):665\u2013670."},{"issue":"1","key":"b14","series-title":"Ann Transl Med","first-page":"16","article-title":"Balance diagnostics after propensity score matching","volume":"7","author":"Zhang Z","year":"2019","unstructured":"Zhang Z, Kim HJ, Lonjon G, Zhu Y. Balance diagnostics after propensity score matching. Ann Transl Med. 2019;7(1):16."},{"issue":"1","key":"b15","series-title":"J Neurosurg Spine","first-page":"84","article-title":"Surgical treatment of young adults with idiopathic scoliosis","volume":"38","author":"Walker CT","year":"2023","unstructured":"Walker CT, Agarwal N, Eastlack RK,  Surgical treatment of young adults with idiopathic scoliosis. J Neurosurg Spine. 2023;38(1):84\u201390."},{"issue":"5","key":"b16","series-title":"JBJS","first-page":"702","article-title":"Idiopathic scoliosis: long-term follow-up and prognosis in untreated patients","volume":"63","author":"Weinstein SL","year":"1981","unstructured":"Weinstein SL, Zavala DC, Ponseti IV. Idiopathic scoliosis: long-term follow-up and prognosis in untreated patients. JBJS. 1981;63(5):702\u2013712."},{"issue":"2","key":"b17","series-title":"J Orthop Sci","first-page":"133","article-title":"Factors affecting curve flexibility in skeletally immature and mature idiopathic scoliosis","volume":"16","author":"Chen ZQ","year":"2011","unstructured":"Chen ZQ, Zhao YF, Bai YS,  Factors affecting curve flexibility in skeletally immature and mature idiopathic scoliosis. J Orthop Sci. 2011;16(2):133\u2013138."},{"issue":"19","key":"b18","series-title":"Spine (Phila Pa 1976)","first-page":"E1133","article-title":"Comparison of surgical outcome of adolescent idiopathic scoliosis and young adult idiopathic scoliosis: a match-pair analysis of 160 patients","volume":"42","author":"Zhu F","year":"2017","unstructured":"Zhu F, Bao H, Yan P,  Comparison of surgical outcome of adolescent idiopathic scoliosis and young adult idiopathic scoliosis: a match-pair analysis of 160 patients. 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Spine (Phila Pa 1976). 2002;27(21):2346\u20132349."},{"issue":"1","key":"b21","series-title":"BMC Musculoskelet Disord","first-page":"126","article-title":"Correlation between supine flexibility and postoperative correction in adolescent idiopathic scoliosis","volume":"24","author":"Zhang M","year":"2023","unstructured":"Zhang M, Chen W, Wang S, Du Y, Zhang J, Pu F. Correlation between supine flexibility and postoperative correction in adolescent idiopathic scoliosis. BMC Musculoskelet Disord. 2023;24(1):126."},{"issue":"21","key":"b22","series-title":"Spine (Phila Pa 1976)","first-page":"1483","article-title":"The effects of body mass index and spine flexibility on surgical outcomes for patients with adolescent idiopathic scoliosis","volume":"47","author":"Linden GS","year":"2022","unstructured":"Linden GS, Hresko MT, Cook D, Birch CM, Hedequist DJ, Hogue GD. The effects of body mass index and spine flexibility on surgical outcomes for patients with adolescent idiopathic scoliosis. 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JAMA. 2018;319(2):165\u2013172."},{"key":"b2","series-title":"Preventive Services Task Force","article-title":"Screening for adolescent idiopathic scoliosis: a systematic evidence review for the U.S","author":"Dunn J","year":"2018","unstructured":"Dunn J, Henrikson NB, Morrison CC, Nguyen M, Blasi PR, Lin JS. Screening for adolescent idiopathic scoliosis: a systematic evidence review for the U.S. Preventive Services Task Force. 2018.Accessed April 28, 2025. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK493367\/"},{"issue":"1","key":"b3","series-title":"J Child Orthop","first-page":"3","article-title":"Epidemiology of adolescent idiopathic scoliosis","volume":"7","author":"Konieczny MR","year":"2013","unstructured":"Konieczny MR, Senyurt H, Krauspe R. Epidemiology of adolescent idiopathic scoliosis. J Child Orthop. 2013;7(1):3\u20139."},{"issue":"3","key":"b4","series-title":"Spine Deform","first-page":"643","article-title":"Outcomes for nighttime bracing in adolescent idiopathic scoliosis based on brace wear adherence","volume":"12","author":"Zapata KA","year":"2024","unstructured":"Zapata KA, Virostek D, Ma Y,  Outcomes for nighttime bracing in adolescent idiopathic scoliosis based on brace wear adherence. Spine Deform. 2024;12(3):643\u2013650."},{"key":"b5","series-title":"Physiotherapy","first-page":"46","article-title":"The effects of physiotherapeutic scoliosis-specific exercise on idiopathic scoliosis in children and adolescents: a systematic review and meta-analysis","volume":"121","author":"Ma K","year":"2023","unstructured":"Ma K, Wang C, Huang Y, Wang Y, Li D, He G. The effects of physiotherapeutic scoliosis-specific exercise on idiopathic scoliosis in children and adolescents: a systematic review and meta-analysis. 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Patient Saf Surg. 2008;2(1):25."},{"issue":"5","key":"b8","series-title":"Spine Deform","first-page":"1133","article-title":"Comparison of operative implications between adolescent and young adult idiopathic scoliosis patients from scoliosis research society mortality and morbidity database","volume":"10","author":"Kurra S","year":"2022","unstructured":"Kurra S, DeMercurio P, Lavelle WF. Comparison of operative implications between adolescent and young adult idiopathic scoliosis patients from scoliosis research society mortality and morbidity database. Spine Deform. 2022;10(5):1133\u20131138."},{"issue":"1","key":"b9","series-title":"Global Spine J","first-page":"81","article-title":"A comparison between the perioperative outcomes of female Adolescent Idiopathic Scoliosis (AIS) versus Adult Idiopathic Scoliosis (AdIS) following posterior spinal fusion: a propensity score matching analysis involving 425 patients","volume":"13","author":"Chan CYW","year":"2023","unstructured":"Chan CYW, Gani SMA, Chung WH, Chiu CK, Hasan MS, Kwan MK. A comparison between the perioperative outcomes of female Adolescent Idiopathic Scoliosis (AIS) versus Adult Idiopathic Scoliosis (AdIS) following posterior spinal fusion: a propensity score matching analysis involving 425 patients. Global Spine J. 2023;13(1):81\u201388."},{"issue":"5","key":"b10","series-title":"Cureus","first-page":"e8118","article-title":"Clinical outcomes of idiopathic scoliosis surgery: is there a difference between young adult patients and adolescent patients?","volume":"12","author":"Lavelle W","year":"2020","unstructured":"Lavelle W, Kurra S, Hu X, Lieberman I. Clinical outcomes of idiopathic scoliosis surgery: is there a difference between young adult patients and adolescent patients?. Cureus. 2020;12(5):e8118."},{"issue":"6","key":"b11","series-title":"Spine Deform","first-page":"1443","article-title":"Clinical and radiographic outcomes following correction of idiopathic scoliosis in adolescence vs young adulthood","volume":"11","author":"LaBarge ME","year":"2023","unstructured":"LaBarge ME, Chanbour H, Waddell WH,  Clinical and radiographic outcomes following correction of idiopathic scoliosis in adolescence vs young adulthood. 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