{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:01:23Z","timestamp":1790388083928,"version":"4.1.0"},"reference-count":37,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Meralgia paresthetica (MP) is a neuropathy of the lateral femoral cutaneous nerve (LFCN) manifested by burning pain, allodynia, and sensory loss in the anterolateral thigh. While simple decompression is commonly performed in patients who do not respond to nonoperative measures, LFCN transposition is an alternative technique for which rates of symptomatic relief and surgical complications are presently poorly understood. The authors report the largest prospective case series of outcomes from a series of consecutive patients who underwent LFCN transposition for refractory MP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Patients with idiopathic MP who underwent LFCN transposition by a single surgeon between 2017 and 2024 were prospectively recruited for the study and followed up for a minimum of 1 year postoperatively. Patients with prior ipsilateral decompression or traumatic\/iatrogenic etiology were excluded. The primary outcome was improvement in preoperative symptoms, including pain by numeric rating scale (NRS), burning, allodynia, and hypesthesia. Secondary outcomes included rates of postoperative complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      The authors identified 51 surgically treated patients, of whom 37 met final inclusion criteria. The mean age was 52.5 \u00b1 10.7 years, and the mean BMI was 34.1 \u00b1 7.3 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      . Preoperatively, 73.0% of patients reported burning, 56.8% reported allodynia, and 97.3% had hypesthesia. The mean total operative duration was 116.8 minutes with a skin-to-nerve time of 8.5 minutes. At a mean follow-up of 14.9 months, 66.7% of patients experienced resolution or improvement in burning, 61.9% had improvement in allodynia, and 47.2% reported improved hypesthesia. The mean reduction in the NRS pain score was 6.5 \u00b1 2.8 points, with 89.2% of patients reporting improvement in \u2265 50% of preoperative pain by the final follow-up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>In the largest prospective study of LFCN transposition to date, patients with refractory noniatrogenic MP experienced meaningful improvement in preoperative symptoms, with the most common postsurgical complication being superficial surgical site infection managed nonoperatively.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2026.2.jns251875","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:39Z","timestamp":1784073639000},"page":"1-11","source":"Crossref","is-referenced-by-count":0,"title":["Clinical outcomes following transposition of the lateral femoral cutaneous nerve for meralgia paresthetica: a prospective case series"],"prefix":"10.3171","author":[{"given":"Darius","family":"Ansari","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, University of Wisconsin Hospital and Clinics, Madison; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amruth K. V.","family":"Addanki","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Wisconsin Hospital and Clinics, Madison; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Eslami","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Wisconsin Hospital and Clinics, Madison; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amgad S.","family":"Hanna","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Wisconsin Hospital and Clinics, Madison; and"},{"name":"Department of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"1","key":"b1","series-title":"J Neurosurg","first-page":"76","article-title":"Management of meralgia paresthetica","volume":"74","author":"Williams PH","year":"1991","unstructured":"Williams PH, Trzil KP. Management of meralgia paresthetica. J Neurosurg. 1991;74(1):76\u201380. doi:10.3171\/jns.1991.74.1.0076"},{"issue":"1","key":"b2","series-title":"Neurosurg Rev","first-page":"54","article-title":"Diagnosis and treatment of meralgia paresthetica between 2005 and 2018: a national cohort study","volume":"46","author":"Sch\u00f6nberg B","year":"2023","unstructured":"Sch\u00f6nberg B, Pigorsch M, Huscher D,  Diagnosis and treatment of meralgia paresthetica between 2005 and 2018: a national cohort study. Neurosurg Rev. 2023;46(1):54. doi:10.1007\/s10143-023-01962-0"},{"issue":"16","key":"b3","series-title":"Neurology","first-page":"1538","article-title":"Meralgia paresthetica: relation to obesity, advanced age, and diabetes mellitus","volume":"77","author":"Parisi TJ","year":"2011","unstructured":"Parisi TJ, Mandrekar J, Dyck PJ, Klein CJ. Meralgia paresthetica: relation to obesity, advanced age, and diabetes mellitus. Neurology. 2011;77(16):1538\u20131542. doi:10.1212\/WNL.0b013e318233b356"},{"issue":"3","key":"b4","series-title":"J Neurol","first-page":"294","article-title":"Incidence rates and determinants in meralgia paresthetica in general practice","volume":"251","author":"van Slobbe AM","year":"2004","unstructured":"van Slobbe AM, Bohnen AM, Bernsen RM, Koes BW, Bierma-Zeinstra SM. Incidence rates and determinants in meralgia paresthetica in general practice. J Neurol. 2004;251(3):294\u2013297. doi:10.1007\/s00415-004-0310-x"},{"issue":"5","key":"b5","series-title":"Muscle Nerve","first-page":"646","article-title":"Anatomy of the lateral femoral cutaneous nerve relevant to clinical findings in meralgia paresthetica","volume":"55","author":"Lee SH","year":"2017","unstructured":"Lee SH, Shin KJ, Gil YC, Ha TJ, Koh KS, Song WC. Anatomy of the lateral femoral cutaneous nerve relevant to clinical findings in meralgia paresthetica. Muscle Nerve. 2017;55(5):646\u2013650. doi:10.1002\/mus.25382"},{"issue":"2","key":"b6","series-title":"J Neurosurg","first-page":"496","article-title":"Transposition of the lateral femoral cutaneous nerve","volume":"130","author":"Hanna A","year":"2019","unstructured":"Hanna A. Transposition of the lateral femoral cutaneous nerve. J Neurosurg. 2019;130(2):496\u2013501. doi:10.3171\/2017.8.JNS171120"},{"issue":"3","key":"b7","series-title":"Clin Anat","first-page":"409","article-title":"Lateral femoral cutaneous nerve transposition: renaissance of an old concept in the light of new anatomy","volume":"30","author":"Hanna AS","year":"2017","unstructured":"Hanna AS. Lateral femoral cutaneous nerve transposition: renaissance of an old concept in the light of new anatomy. Clin Anat. 2017;30(3):409\u2013412. doi:10.1002\/ca.22849"},{"key":"b8","series-title":"J Clin Neurosci","first-page":"111469","article-title":"Comprehensive analysis of surgical treatments for meralgia paraesthetica: case series and meta-analysis encompassing results of decompression vs neurectomy","volume":"139","author":"Fortuniak J","year":"2025","unstructured":"Fortuniak J, Hupa\u0142o M, Jask\u00f3lski DJ, Szmyd B. Comprehensive analysis of surgical treatments for meralgia paraesthetica: case series and meta-analysis encompassing results of decompression vs neurectomy. J Clin Neurosci. 2025;139:111469. doi:10.1016\/j.jocn.2025.111469"},{"issue":"1","key":"b9","series-title":"Ann Surg","first-page":"85","article-title":"An osteoplastic neurolysis operation for the cure of meralgia paresthetica","volume":"113","author":"Lee FC","year":"1941","unstructured":"Lee FC. An osteoplastic neurolysis operation for the cure of meralgia paresthetica. Ann Surg. 1941;113(1):85\u201394. doi:10.1097\/00000658-194101000-00012"},{"key":"b10","series-title":"J Neurosurg","first-page":"341","article-title":"Meralgia paresthetica. An anatomical and surgical study","volume":"19","author":"Keegan JJ","year":"1962","unstructured":"Keegan JJ, Holyoke EA. Meralgia paresthetica. An anatomical and surgical study. J Neurosurg. 1962;19:341\u2013345. doi:10.3171\/jns.1962.19.4.0341"},{"issue":"3","key":"b11","series-title":"J Neurosurg","first-page":"492","article-title":"Suprainguinal ligament approach for surgical treatment of meralgia paresthetica. Technical note","volume":"70","author":"Aldrich EF","year":"1989","unstructured":"Aldrich EF, van den Heever CM. Suprainguinal ligament approach for surgical treatment of meralgia paresthetica. Technical note. J Neurosurg. 1989;70(3):492\u2013494. doi:10.3171\/jns.1989.70.3.0492"},{"issue":"9695","key":"b12","series-title":"Lancet","first-page":"1105","article-title":"No surgical innovation without evaluation: the IDEAL recommendations","volume":"374","author":"McCulloch P","year":"2009","unstructured":"McCulloch P, Altman DG, Campbell WB,  No surgical innovation without evaluation: the IDEAL recommendations. Lancet. 2009;374(9695):1105\u20131112. doi:10.1016\/S0140-6736(09)61116-8"},{"issue":"17","key":"b13","series-title":"Neurology","first-page":"1551","article-title":"Chronic meralgia paresthetica and neurectomy: a clinical pathologic study","volume":"82","author":"Berini SE","year":"2014","unstructured":"Berini SE, Spinner RJ, Jentoft ME,  Chronic meralgia paresthetica and neurectomy: a clinical pathologic study. Neurology. 2014;82(17):1551\u20131555. doi:10.1212\/WNL.0000000000000367"},{"issue":"1","key":"b14","series-title":"Neurosurg Focus Video","first-page":"V8","article-title":"Lateral femoral cutaneous nerve transposition","volume":"8","author":"Greeneway GP","year":"2023","unstructured":"Greeneway GP, Page PS, Ammanuel SG, Hanna AS. Lateral femoral cutaneous nerve transposition. Neurosurg Focus Video. 2023;8(1):V8. doi:10.3171\/2022.10.FOCVID2289"},{"issue":"3","key":"b15","series-title":"Oper Neurosurg","first-page":"402","article-title":"Preoperative ultrasound-guided wire localization of the lateral femoral cutaneous nerve","volume":"13","author":"Hanna AS","year":"2017","unstructured":"Hanna AS, Ehlers ME, Lee KS. Preoperative ultrasound-guided wire localization of the lateral femoral cutaneous nerve. Oper Neurosurg. 2017;13(3):402\u2013408. doi:10.1093\/ons\/opw009"},{"issue":"1","key":"b16","series-title":"Oper Neurosurg","first-page":"104","article-title":"Lateral femoral cutaneous nerve transposition with ultrasound-guided wire localization: 2-dimensional operative video","volume":"26","author":"Staniszewski T","year":"2024","unstructured":"Staniszewski T, Buckley N, Hanna AS. Lateral femoral cutaneous nerve transposition with ultrasound-guided wire localization: 2-dimensional operative video. Oper Neurosurg. 2024;26(1):104\u2013105. doi:10.1227\/ons.0000000000000903"},{"issue":"9","key":"b17","series-title":"PLoS One","first-page":"e0203345","article-title":"Predictive value of a diagnostic block in focal nerve injury with neuropathic pain when surgery is considered","volume":"13","author":"Malessy MJA","year":"2018","unstructured":"Malessy MJA, de Boer R, Mu\u00f1oz Romero I,  Predictive value of a diagnostic block in focal nerve injury with neuropathic pain when surgery is considered. PLoS One. 2018;13(9):e0203345. doi:10.1371\/journal.pone.0203345"},{"issue":"1","key":"b18","series-title":"Bioinformatics","first-page":"112","article-title":"MissForest - non-parametric missing value imputation for mixed-type data","volume":"28","author":"Stekhoven DJ","year":"2012","unstructured":"Stekhoven DJ, B\u00fchlmann P. MissForest - non-parametric missing value imputation for mixed-type data. Bioinformatics. 2012;28(1):112\u2013118. doi:10.1093\/bioinformatics\/btr597"},{"issue":"12","key":"b19","series-title":"Stat Med","first-page":"1981","article-title":"Application of the McNemar test to non-independent matched pair data","volume":"10","author":"Eliasziw M","year":"1991","unstructured":"Eliasziw M, Donner A. Application of the McNemar test to non-independent matched pair data. Stat Med. 1991;10(12):1981\u20131991. doi:10.1002\/sim.4780101211"},{"issue":"5","key":"b20","series-title":"J Neurosurg","first-page":"1552","article-title":"Dynamic decompression of the lateral femoral cutaneous nerve to treat meralgia paresthetica: technique and results","volume":"131","author":"Malessy MJA","year":"2019","unstructured":"Malessy MJA, Eekhof J, Pondaag W. Dynamic decompression of the lateral femoral cutaneous nerve to treat meralgia paresthetica: technique and results. J Neurosurg. 2019;131(5):1552\u20131560. doi:10.3171\/2018.9.JNS182004"},{"issue":"6","key":"b21","series-title":"J Korean Neurosurg Soc","first-page":"363","article-title":"Neurolysis for meralgia paresthetica","volume":"51","author":"Son BC","year":"2012","unstructured":"Son BC, Kim DR, Kim IS, Hong JT, Sung JH, Lee SW. Neurolysis for meralgia paresthetica. J Korean Neurosurg Soc. 2012;51(6):363\u2013366. doi:10.3340\/jkns.2012.51.6.363"},{"issue":"1","key":"b22","series-title":"Surg Neurol","first-page":"19","article-title":"Neurolysis for meralgia paresthetica: an operative series of 45 cases","volume":"63","author":"Siu TL","year":"2005","unstructured":"Siu TL, Chandran KN. Neurolysis for meralgia paresthetica: an operative series of 45 cases. Surg Neurol. 2005;63(1):19\u201323. doi:10.1016\/j.surneu.2004.07.035"},{"issue":"1","key":"b23","series-title":"Neurosurgery","first-page":"63","article-title":"Operative treatment of meralgia paresthetica: transection versus neurolysis","volume":"37","author":"van Eerten PV","year":"1995","unstructured":"van Eerten PV, Polder TW, Broere CA. Operative treatment of meralgia paresthetica: transection versus neurolysis. Neurosurgery. 1995;37(1):63\u201365. doi:10.1227\/00006123-199507000-00009"},{"issue":"Suppl 1","key":"b24","series-title":"Surg Infect (Larchmt)","first-page":"S7","article-title":"Risk factors for surgical site infection","volume":"7","author":"Cheadle WG","year":"2006","unstructured":"Cheadle WG. Risk factors for surgical site infection. Surg Infect (Larchmt). 2006;7 Suppl 1:S7\u2013S11. doi:10.1089\/sur.2006.7.s1-7"},{"issue":"1","key":"b25","series-title":"Acta Orthop","first-page":"87","article-title":"Bacterial colonization and resistance patterns in 133 patients undergoing a primary hip- or knee replacement in Southern Sweden","volume":"84","author":"Stef\u00e1nsd\u00f3ttir A","year":"2013","unstructured":"Stef\u00e1nsd\u00f3ttir A, Johansson \u00c5, Lidgren L, Wagner P, W-Dahl A. Bacterial colonization and resistance patterns in 133 patients undergoing a primary hip- or knee replacement in Southern Sweden. Acta Orthop. 2013;84(1):87\u201391. doi:10.3109\/17453674.2013.773120"},{"issue":"8","key":"b26","series-title":"J Hand Surg Am","first-page":"766","article-title":"What is a surgical site infection after carpal tunnel release?","volume":"49","author":"Sandefur EP","year":"2024","unstructured":"Sandefur EP, Beck JH, Vest MO, Yu-Shan AA, Vaughn NH, Apel PJ. What is a surgical site infection after carpal tunnel release? J Hand Surg Am. 2024;49(8):766\u2013771. doi:10.1016\/j.jhsa.2023.12.014"},{"issue":"1","key":"b27","series-title":"Acta Med Port","first-page":"55","article-title":"Monitoring antibiotic consumption in the surgery and orthopaedics","volume":"19","author":"Caldeira L","year":"2006","unstructured":"Caldeira L, Teixeira I, Vieira I,  Monitoring antibiotic consumption in the surgery and orthopaedics. Article in Portugese. Acta Med Port. 2006;19(1):55\u201366."},{"issue":"6","key":"b28","series-title":"J Neurosurg","first-page":"2020","article-title":"Letter to the Editor. Meralgia paresthetica: what to do?","volume":"132","author":"Hanna A","year":"2020","unstructured":"Hanna A. Letter to the Editor. Meralgia paresthetica: what to do? J Neurosurg. 2020;132(6):2020\u20132021. doi:10.3171\/2019.10.JNS192708"},{"issue":"5","key":"b29","series-title":"Acta Neurochir (Wien)","first-page":"931","article-title":"Evaluating the evidence: is neurolysis or neurectomy a better treatment for meralgia paresthetica?","volume":"159","author":"Payne R","year":"2017","unstructured":"Payne R, Seaman S, Sieg E, Langan S, Harbaugh K, Rizk E. Evaluating the evidence: is neurolysis or neurectomy a better treatment for meralgia paresthetica? Acta Neurochir (Wien). 2017;159(5):931\u2013936. doi:10.1007\/s00701-017-3136-x"},{"key":"b30","series-title":"Clin Neurol Neurosurg","first-page":"7","article-title":"Comparison of effectiveness of different surgical treatments for meralgia paresthetica: results of a prospective observational study and protocol for a randomized controlled trial","volume":"134","author":"de Ruiter GC","year":"2015","unstructured":"de Ruiter GC, Kloet A. Comparison of effectiveness of different surgical treatments for meralgia paresthetica: results of a prospective observational study and protocol for a randomized controlled trial. Clin Neurol Neurosurg. 2015;134:7\u201311. doi:10.1016\/j.clineuro.2015.04.007"},{"issue":"5","key":"b31","series-title":"Muscle Nerve","first-page":"659","article-title":"Lateral femoral cutaneous neuropathy and its surgical treatment: a report of 167 cases","volume":"36","author":"Benezis I","year":"2007","unstructured":"Benezis I, Boutaud B, Leclerc J, Fabre T, Durandeau A. Lateral femoral cutaneous neuropathy and its surgical treatment: a report of 167 cases. Muscle Nerve. 2007;36(5):659\u2013663. doi:10.1002\/mus.20868"},{"issue":"8","key":"b32","series-title":"Nervenarzt","first-page":"614","article-title":"Meralgia paraesthetica and its surgical treatment","volume":"66","author":"Antoniadis G","year":"1995","unstructured":"Antoniadis G, Braun V, Rath S, Moese G, Richter HP. Meralgia paraesthetica and its surgical treatment. Article in German. Nervenarzt. 1995;66(8):614\u2013617."},{"key":"b33","series-title":"World Neurosurg","first-page":"e830","article-title":"Suprainguinal re-resection of the lateral femoral cutaneous nerve in persistence or recurrence of meralgia paresthetica after previous transection: results of a case series","volume":"155","author":"de Ruiter GCW","year":"2021","unstructured":"de Ruiter GCW, Clahsen PC, Oosterhuis JWA. Suprainguinal re-resection of the lateral femoral cutaneous nerve in persistence or recurrence of meralgia paresthetica after previous transection: results of a case series. World Neurosurg. 2021;155:e830\u2013e835. doi:10.1016\/j.wneu.2021.09.022"},{"key":"b34","series-title":"West J Surg Obstet Gynecol","first-page":"390","article-title":"Meralgia paresthetica; new causal observations","volume":"54","author":"Mack EW","year":"1946","unstructured":"Mack EW. Meralgia paresthetica; new causal observations. West J Surg Obstet Gynecol. 1946;54:390."},{"issue":"2","key":"b35","series-title":"Oper Neurosurg","first-page":"174","article-title":"Preoperative ultrasound-guided localization of the lateral femoral cutaneous nerve: from guide wire to novel clip","volume":"27","author":"Koueik J","year":"2024","unstructured":"Koueik J, Bethel JA, Lee KS, Tuite MJ, Hanna AS. Preoperative ultrasound-guided localization of the lateral femoral cutaneous nerve: from guide wire to novel clip. Oper Neurosurg. 2024;27(2):174\u2013179. doi:10.1227\/ons.0000000000001072"},{"issue":"10","key":"b36","series-title":"Acta Neurochir (Wien)","first-page":"1765","article-title":"Decision making in the surgical treatment of meralgia paresthetica: neurolysis versus neurectomy","volume":"154","author":"de Ruiter GC","year":"2012","unstructured":"de Ruiter GC, Wurzer JA, Kloet A. Decision making in the surgical treatment of meralgia paresthetica: neurolysis versus neurectomy. Acta Neurochir (Wien). 2012;154(10):1765\u20131772. doi:10.1007\/s00701-012-1431-0"},{"issue":"15","key":"b37","series-title":"CMAJ","first-page":"1638","article-title":"Registration of observational studies: is it time?","volume":"182","author":"Williams RJ","year":"2010","unstructured":"Williams RJ, Tse T, Harlan WR, Zarin DA. Registration of observational studies: is it time? CMAJ. 2010;182(15):1638\u20131642. doi:10.1503\/cmaj.092252"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/aop\/article-10.3171-2026.2.JNS251875\/article-10.3171-2026.2.JNS251875.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/aop\/article-10.3171-2026.2.JNS251875\/article-10.3171-2026.2.JNS251875.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T01:46:38Z","timestamp":1790387198000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/aop\/article-10.3171-2026.2.JNS251875\/article-10.3171-2026.2.JNS251875.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,1]]},"references-count":37,"URL":"https:\/\/doi.org\/10.3171\/2026.2.jns251875","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,1]]}}}