{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:37:11Z","timestamp":1792809431041,"version":"4.5.0"},"reference-count":24,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>The incidence of vestibular schwannoma (VS) diagnosis among octogenarians has increased due to longer life expectancy and greater MRI accessibility and utilization. Stereotactic radiosurgery (SRS) offers a safe management strategy for these patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The authors retrospectively analyzed the data of octogenarians with VS managed with SRS across 27 institutions, assessing clinical and audiological outcomes, including survival rates, tumor control responses, complications, and posttreatment functional outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Among 309 octogenarians with VS managed with single-fraction SRS, overall survival was 97.8% at 1 year, 88.5% at 3 years, and 78.1% at 5 years; the corresponding progression-free survival rates were 95.8%, 81.1%, and 71.1%, respectively. In competing risk analysis, tumor progression occurred in 5.2% of patients by 5 years, whereas death without progression reached 19.8%. Tumor control was achieved in 94.8% at 3 and 5 years. At last imaging follow-up (median 33.5 months, IQR 14\u201360 months), 29.1% showed volume regression. Communicating hydrocephalus developed in 4.2% and was successfully managed with CSF diversion. Age, sex, tumor volume, Koos grade, and margin dose were not significant predictors of patient survival or tumor progression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Single-fraction SRS is a safe and effective management modality for octogenarians with VS, providing durable tumor control with minimal morbidity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2026.2.jns252486","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:02:21Z","timestamp":1785888141000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["The role of stereotactic radiosurgery in the management of vestibular schwannoma in octogenarians: an international multi-institutional study"],"prefix":"10.3171","author":[{"given":"Hussam","family":"Abou-Al-Shaar","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh;"},{"name":"Vivian L. Smith Department of Neurosurgery, University of Texas Health Science Center at Houston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahem","family":"Albalkhi","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Othman","family":"Bin-Alamer","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffery R.","family":"Head","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arka N.","family":"Mallela","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney E.","family":"Wegner","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Allegheny Health Network Cancer Institute, Pittsburgh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trent","family":"Kite","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Allegheny Health Network, Pittsburgh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean S.","family":"Mahase","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Penn State Cancer Institute and College of Medicine, Hershey;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara","family":"Nolan","sequence":"additional","affiliation":[{"name":"Penn State College of Medicine, Hershey;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad E.","family":"Zacharia","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Penn State Health, Hershey, Pennsylvania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bailey","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Penn State Health, Hershey, Pennsylvania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Chia","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei;"},{"name":"School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huai-Che","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei;"},{"name":"School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg N.","family":"Bowden","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Alberta, Edmonton, Alberta, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bardia","family":"Hajikarimloo","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Southern California, Los Angeles;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Southern California, Los Angeles;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University of Southern California, Los Angeles, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Amezquita-Contreras","sequence":"additional","affiliation":[{"name":"Vivian L. 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Arch Otolaryngol Head Neck Surg. 2005;131(3):241\u2013244. doi:10.1001\/archotol.131.3.241"},{"key":"b4","series-title":"Clin Epidemiol","first-page":"981","article-title":"Epidemiology of vestibular schwannomas\u2014prospective 40-year data from an unselected national cohort","volume":"11","author":"Reznitsky M","year":"2019","unstructured":"Reznitsky M, Petersen MMBS, West N, Stangerup SE, Cay\u00e9-Thomasen P. Epidemiology of vestibular schwannomas\u2014prospective 40-year data from an unselected national cohort. Clin Epidemiol. 2019;11:981\u2013986. doi:10.2147\/CLEP.S218670"},{"issue":"3","key":"b5","series-title":"Otolaryngol Head Neck Surg","first-page":"440","article-title":"The changing landscape of vestibular schwannoma management in the United States\u2014a shift toward conservatism","volume":"153","author":"Carlson ML","year":"2015","unstructured":"Carlson ML, Habermann EB, Wagie AE,  The changing landscape of vestibular schwannoma management in the United States\u2014a shift toward conservatism. Otolaryngol Head Neck Surg. 2015;153(3):440\u2013446. doi:10.1177\/0194599815590105"},{"issue":"9","key":"b6","series-title":"Otol Neurotol","first-page":"e1358","article-title":"Surgical outcomes after conservative resection of vestibular schwannoma in the elderly","volume":"42","author":"Luryi AL","year":"2021","unstructured":"Luryi AL, Babu S, Bojrab DI, Kveton JF, Schutt CA. Surgical outcomes after conservative resection of vestibular schwannoma in the elderly. Otol Neurotol. 2021;42(9):e1358\u2013e1361. doi:10.1097\/MAO.0000000000003251"},{"issue":"5","key":"b7","series-title":"Neurosurgery","first-page":"1099","article-title":"Vestibular schwannoma stereotactic radiosurgery in octogenarians: case series","volume":"93","author":"Head JR","year":"2023","unstructured":"Head JR, Bin-Alamer O, Wei Z,  Vestibular schwannoma stereotactic radiosurgery in octogenarians: case series. Neurosurgery. 2023;93(5):1099\u20131105. doi:10.1227\/neu.0000000000002552"},{"key":"b8","series-title":"Survival Analysis with Python","author":"Nag A","year":"2021","unstructured":"Nag A. Survival Analysis with Python. Auerbach Publications;2021. doi:10.1201\/9781003255499"},{"issue":"3","key":"b9","series-title":"Ann Transl Med","first-page":"47","article-title":"Survival analysis in the presence of competing risks","volume":"5","author":"Zhang Z","year":"2017","unstructured":"Zhang Z. Survival analysis in the presence of competing risks. Ann Transl Med. 2017;5(3):47. doi:10.21037\/atm.2016.08.62"},{"issue":"1","key":"b10","series-title":"Biometrics","first-page":"73","article-title":"Maximally selected rank statistics","volume":"48","author":"Lausen B","year":"1992","unstructured":"Lausen B, Schumacher M. Maximally selected rank statistics. Biometrics. 1992;48(1):73\u201385. doi:10.2307\/2532740"},{"issue":"1","key":"b11","series-title":"Biometrika","first-page":"239","article-title":"Partial residuals for the proportional hazards regression model","volume":"69","author":"Schoenfeld D","year":"1982","unstructured":"Schoenfeld D. Partial residuals for the proportional hazards regression model. Biometrika. 1982;69(1):239\u2013241. doi:10.1093\/biomet\/69.1.239"},{"issue":"1","key":"b12","series-title":"J Radiosurgery SBRT","first-page":"5","article-title":"Stereotactic radiosurgery for vestibular schwannoma: International Stereotactic Radiosurgery Society (ISRS) Practice Guideline","volume":"5","author":"Tsao MN","year":"2017","unstructured":"Tsao MN, Sahgal A, Xu W,  Stereotactic radiosurgery for vestibular schwannoma: International Stereotactic Radiosurgery Society (ISRS) Practice Guideline. J Radiosurgery SBRT. 2017;5(1):5\u201324."},{"issue":"6","key":"b13","series-title":"Neurosurgery","first-page":"1130","article-title":"Long-term hearing outcome after radiosurgery for vestibular schwannoma: a systematic review and meta-analysis","volume":"92","author":"Balossier A","year":"2023","unstructured":"Balossier A, Tuleasca C, Delsanti C,  Long-term hearing outcome after radiosurgery for vestibular schwannoma: a systematic review and meta-analysis. 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J Neurosurg. 2005;103(1):59\u201363. doi:10.3171\/jns.2005.103.1.0059"},{"issue":"4","key":"b17","series-title":"Otol Neurotol","first-page":"547","article-title":"The natural history of vestibular schwannoma","volume":"27","author":"Stangerup SE","year":"2006","unstructured":"Stangerup SE, Caye-Thomasen P, Tos M, Thomsen J. The natural history of vestibular schwannoma. Otol Neurotol. 2006;27(4):547\u2013552. doi:10.1097\/01.mao.0000217356.73463.e7"},{"issue":"2","key":"b18","series-title":"J Neurooncol","first-page":"247","article-title":"Long term results of primary radiosurgery for vestibular schwannomas","volume":"145","author":"Johnson S","year":"2019","unstructured":"Johnson S, Kano H, Faramand A,  Long term results of primary radiosurgery for vestibular schwannomas. J Neurooncol. 2019;145(2):247\u2013255. doi:10.1007\/s11060-019-03290-0"},{"key":"b19","first-page":"58","article-title":"Surgical treatment of vestibular schwannoma: does age matter? 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