{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T04:57:28Z","timestamp":1770353848238,"version":"3.49.0"},"reference-count":28,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"22","license":[{"start":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T00:00:00Z","timestamp":1622419200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,5,31]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Cavum trigeminale cephaloceles (CTCs) are characterized by a cystic appearance and extension of the posterolateral aspect of Meckel\u2019s cave into the superomedial portion of the petrous apex. A possible mechanism is a transient or sustained increase of intracranial pressure transmitted to Meckel\u2019s cave, leading to its secondary herniation, in the presence of predisposing local factors. The majority of CTCs are incidental findings. Among symptomatic cases, headache, trigeminal neuralgia, cerebrospinal fluid leak, vertigo, ataxia, facial numbness, hearing loss, diplopia, and other visual disturbances have been described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>The authors describe a case of an 18-month-old male patient referred to their hospital with drowsiness, vomiting, left cranial nerve VI palsy, and papilledema. Neuroradiological investigation revealed the presence of a CTC with a swollen aspect of the left pontine hemisection and indirect signs of intracranial hypertension. The patient was managed with implantation of a ventriculoperitoneal shunt.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>CTCs are rare lesions that are difficult to recognize on neuroimaging, in which they can be mistaken for tumoral or inflammatory lesions. The most frequent asymptomatic forms should be considered as \u201cleave-me-alone\u201d lesions. In cases of intracranial hypertension, according to a supposed theory on the origin of CTCs, the authors recommend treating only the intracranial hypertension instead of performing more invasive surgical procedures, especially in pediatric patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case21136","type":"journal-article","created":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T03:02:47Z","timestamp":1622430167000},"source":"Crossref","is-referenced-by-count":1,"title":["Cavum trigeminale cephalocele associated with intracranial hypertension in an 18-month-old child: illustrative case"],"prefix":"10.3171","volume":"1","author":[{"given":"Giovanni","family":"Miccoli","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Pediatric Neurosurgery Unit, Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy"},{"name":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, Division of Neurosurgery, University Federico II, Naples, Italy; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Cicala","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Division of Neuroradiology, Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Spennato","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Pediatric Neurosurgery Unit, Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia","family":"Imperato","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Pediatric Neurosurgery Unit, Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Ruggiero","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Pediatric Neurosurgery Unit, Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Cinalli","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Pediatric Neurosurgery Unit, Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"3","key":"b1","series-title":"Eur J Radiol","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1016\/j.ejrad.2007.01.010","article-title":"Petrous apex cephalocele and empty sella: is there any relation?","volume":"62","author":"Alorainy IA","year":"2007","unstructured":"Alorainy IA. 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