{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:16:01Z","timestamp":1792642561401,"version":"4.5.0"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","license":[{"start":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T00:00:00Z","timestamp":1626048000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,12]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Ehlers-Danlos syndrome (EDS) and its connective tissue laxity often result in high-grade lumbosacral spondylolisthesis. Patients present with debilitating symptoms and neurological deficits. Reports of surgical techniques in non-EDS patients for the treatment of high-grade lumbosacral spondylolisthesis mainly described an open approach, multilevel fusions, and multiple stages with different circumferential approaches. Sagittal adjusting screws (SASs) can be used in a minimally invasive (MI) fashion, allowing intraoperative reduction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 17-year-old female with EDS presented to the authors\u2019 institute with severe lower back and left L5 radicular pain in 2017. She presented with a left foot drop and difficulty ambulating. Magnetic resonance imaging showed grade IV L5\u2013S1 spondylolisthesis. She underwent lumbar fusion for intractable back pain with radiculopathy. Intraoperatively, percutaneous SASs and extension towers were used to distract the L5\u2013S1 disc space and reduce the spondylolisthesis. MI transforaminal lumbar interbody fusion was completed with significant symptomatic relief postoperatively. The patient was discharged to home 3 days postoperatively. Routine follow-up visits up to 3 years later demonstrated solid fusion radiographically and favorable patient-reported outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>The authors used SASs in a MI approach to successfully correct and stabilize grade IV spondylolisthesis in an EDS patient with a favorable long-term patient-reported outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case21196","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T03:03:10Z","timestamp":1626058990000},"source":"Crossref","is-referenced-by-count":1,"title":["Sagittal adjusting screws for the correction of grade IV spondylolisthesis in a patient with Ehlers-Danlos syndrome: illustrative case"],"prefix":"10.3171","volume":"2","author":[{"given":"Jake","family":"Jasinski","sequence":"first","affiliation":[{"name":"Division of Neurosurgery, Ascension Providence Hospital, College of Human Medicine, Michigan State University, Southfield, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doris","family":"Tong","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Ascension Providence Hospital, College of Human Medicine, Michigan State University, Southfield, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Connor","family":"Hanson","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Ascension Providence Hospital, College of Human Medicine, Michigan State University, Southfield, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teck","family":"Soo","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Ascension Providence Hospital, College of Human Medicine, Michigan State University, Southfield, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"4","key":"b1","series-title":"World J Clin Cases","doi-asserted-by":"publisher","first-page":"532","DOI":"10.12998\/wjcc.v7.i4.532","article-title":"Anterior cervical corpectomy decompression and fusion for cervical kyphosis in a girl with Ehlers-Danlos syndrome: a case report","volume":"7","author":"Fang H","year":"2019","unstructured":"Fang H, Liu P-F, Ge C,  Anterior cervical corpectomy decompression and fusion for cervical kyphosis in a girl with Ehlers-Danlos syndrome: a case report. World J Clin Cases. 2019;7(4):532\u2013537.10.12998\/wjcc.v7.i4.532"},{"issue":"6","key":"b2","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1097\/00007632-199603150-00014","article-title":"Surgical treatment of severe L5-S1 spondylolisthesis in children and adolescents. Results of intraoperative reduction, posterior interbody fusion, and segmental pedicle fixation","volume":"21","author":"Fabris DA","year":"1996","unstructured":"Fabris DA, Costantini S, Nena U. Surgical treatment of severe L5-S1 spondylolisthesis in children and adolescents. Results of intraoperative reduction, posterior interbody fusion, and segmental pedicle fixation. Spine (Phila Pa 1976). 1996;21(6):728\u2013733.10.1097\/00007632-199603150-0001428928499"},{"issue":"7","key":"b3","series-title":"J Bone Joint Surg Am","doi-asserted-by":"publisher","first-page":"960","DOI":"10.2106\/00004623-198769070-00002","article-title":"Long-term follow-up of patients with grade-III and IV spondylolisthesis. Treatment with and without posterior fusion","volume":"69","author":"Harris IE","year":"1987","unstructured":"Harris IE, Weinstein SL. Long-term follow-up of patients with grade-III and IV spondylolisthesis. Treatment with and without posterior fusion. J Bone Joint Surg Am. 1987;69(7):960\u2013969.10.2106\/00004623-198769070-0000231747221"},{"issue":"2","key":"b4","series-title":"Neurosurg Clin N Am","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.nec.2007.01.001","article-title":"Operative management of adult high-grade lumbosacral spondylolisthesis","volume":"18","author":"Acosta FL Jr","year":"2007","unstructured":"Acosta FL Jr, Ames CP, Chou D. Operative management of adult high-grade lumbosacral spondylolisthesis. Neurosurg Clin N Am. 2007;18(2):249\u2013254.10.1016\/j.nec.2007.01.001"},{"key":"b5","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"S49","DOI":"10.1097\/01.brs.0000155573.34179.7e","article-title":"Evaluation and management of high-grade spondylolisthesis in adults","volume":"30","author":"DeWald CJ","year":"2005","unstructured":"DeWald CJ, Vartabedian JE, Rodts MF, Hammerberg KW. Evaluation and management of high-grade spondylolisthesis in adults. Spine (Phila Pa 1976). 2005;30(6 suppl):S49\u2013S59.10.1097\/01.brs.0000155573.34179.7e28928499"},{"issue":"3","key":"b6","series-title":"Neurosurg Clin N Am","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.nec.2019.02.002","article-title":"High-grade lumbar spondylolisthesis","volume":"30","author":"Beck AW","year":"2019","unstructured":"Beck AW, Simpson AK. High-grade lumbar spondylolisthesis. Neurosurg Clin N Am. 2019;30(3):291\u2013298.10.1016\/j.nec.2019.02.00231747221"},{"issue":"5","key":"b7","series-title":"J Pediatr Orthop B","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1097\/01202412-200409000-00011","article-title":"Non-adjacent spondylolisthesis in Ehlers-Danlos syndrome","volume":"13","author":"Nematbakhsh A","year":"2004","unstructured":"Nematbakhsh A, Crawford AH. Non-adjacent spondylolisthesis in Ehlers-Danlos syndrome. J Pediatr Orthop B. 2004;13(5):336\u2013339.10.1097\/01202412-200409000-00011"},{"issue":"2","key":"b8","series-title":"J Spinal Disord Tech","doi-asserted-by":"publisher","first-page":"E41","DOI":"10.1097\/BSD.0b013e31829649fa","article-title":"A novel minimally invasive technique for the treatment of high-grade isthmic spondylolisthesis using a posterior transsacral rod","volume":"27","author":"Shedid D","year":"2014","unstructured":"Shedid D, Weil AG, Lieberman I. A novel minimally invasive technique for the treatment of high-grade isthmic spondylolisthesis using a posterior transsacral rod. J Spinal Disord Tech. 2014;27(2):E41\u2013E48.10.1097\/BSD.0b013e31829649fa"},{"key":"b9","article-title":"Medtronic Announces new screw for market-leading CD HORIZON solera spinal system","author":"Rocha V","unstructured":"Rocha V, Warren J. Medtronic Announces new screw for market-leading CD HORIZON solera spinal system. Medtronic. July 11, 2013. Accessed March 29, 2021. https:\/\/news.medtronic.com\/2013-07-11-Medtronic-Announces-New-Screw-for-Market-Leading-CD-HORIZON-R-SOLERA-R-Spinal-System"},{"issue":"2","key":"b10","series-title":"J Can Chiropr Assoc","first-page":"162","article-title":"High-grade spondylolytic spondylolisthesis","volume":"61","author":"Emary PC","year":"2017","unstructured":"Emary PC, Eberspaecher SA, Taylor JA. High-grade spondylolytic spondylolisthesis. J Can Chiropr Assoc. 2017;61(2):162\u2013166."},{"key":"b11","article-title":"Ehlers Danlos syndrome","author":"Miklovic T","unstructured":"Miklovic T, Sieg VC. Ehlers Danlos syndrome. StatPearls. 2021. Accessed March 29, 2021. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK549814\/"},{"key":"b12","series-title":"Surg Neurol Int","doi-asserted-by":"publisher","first-page":"416","DOI":"10.25259\/SNI_676_2020","article-title":"Pedicular lumbosacral spine fusion for adult\/adolescent lumbar developmental high-grade spondylolisthesis","volume":"11","author":"Elnokaly MA","year":"2020","unstructured":"Elnokaly MA, Adawi MM, Nabeel AM. Pedicular lumbosacral spine fusion for adult\/adolescent lumbar developmental high-grade spondylolisthesis. Surg Neurol Int. 2020;11:416.10.25259\/SNI_676_2020"},{"issue":"4","key":"b13","series-title":"J Spine Surg","doi-asserted-by":"publisher","first-page":"650","DOI":"10.21037\/jss-20-597","article-title":"Retrospective radiographic analysis of anterior lumbar fusion for high grade lumbar spondylolisthesis","volume":"6","author":"Kalani MA","year":"2020","unstructured":"Kalani MA, Kouloumberis P, Richards AE,  Retrospective radiographic analysis of anterior lumbar fusion for high grade lumbar spondylolisthesis. J Spine Surg. 2020;6(4):650\u2013658.10.21037\/jss-20-597"},{"issue":"2","key":"b14","series-title":"Orthop Traumatol Surg Res","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.otsr.2015.12.016","article-title":"Reduction and fusion in high-grade L5-S1 spondylolisthesis by a single posterior approach. Results in 50 patients","volume":"102","author":"Moreau S","year":"2016","unstructured":"Moreau S, Lonjon G, Guigui P,  Reduction and fusion in high-grade L5-S1 spondylolisthesis by a single posterior approach. Results in 50 patients. Orthop Traumatol Surg Res. 2016;102(2):233\u2013237.10.1016\/j.otsr.2015.12.016"},{"issue":"6","key":"b15","series-title":"Clin Orthop Relat Res","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1007\/s11999-013-3241-y","article-title":"Minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis and degenerative spondylosis: 5-year results","volume":"472","author":"Park Y","year":"2014","unstructured":"Park Y, Ha JW, Lee YT, Sung NY. Minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis and degenerative spondylosis: 5-year results. Clin Orthop Relat Res. 2014;472(6):1813\u20131823.10.1007\/s11999-013-3241-y"},{"issue":"6","key":"b16","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1227\/NEU.0000000000000913","article-title":"Surgical outcomes for minimally invasive vs open transforaminal lumbar interbody fusion: an updated systematic review and meta-analysis","volume":"77","author":"Khan NR","year":"2015","unstructured":"Khan NR, Clark AJ, Lee SL,  Surgical outcomes for minimally invasive vs open transforaminal lumbar interbody fusion: an updated systematic review and meta-analysis. Neurosurgery. 2015;77(6):847\u2013874.10.1227\/NEU.0000000000000913"},{"issue":"1","key":"b17","series-title":"J Orthop Surg Res","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1186\/s13018-019-1266-y","article-title":"Open versus minimally invasive TLIF: literature review and meta-analysis","volume":"14","author":"Hammad A","year":"2019","unstructured":"Hammad A, Wirries A, Ardeshiri A,  Open versus minimally invasive TLIF: literature review and meta-analysis. J Orthop Surg Res. 2019;14(1):229.10.1186\/s13018-019-1266-y"},{"issue":"4","key":"b1","series-title":"World J Clin Cases","doi-asserted-by":"publisher","first-page":"532","DOI":"10.12998\/wjcc.v7.i4.532","article-title":"Anterior cervical corpectomy decompression and fusion for cervical kyphosis in a girl with Ehlers-Danlos syndrome: a case report","volume":"7","author":"Fang H","year":"2019","unstructured":"Fang H, Liu P-F, Ge C,  Anterior cervical corpectomy decompression and fusion for cervical kyphosis in a girl with Ehlers-Danlos syndrome: a case report. World J Clin Cases. 2019;7(4):532\u2013537.10.12998\/wjcc.v7.i4.532"},{"issue":"6","key":"b2","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1097\/00007632-199603150-00014","article-title":"Surgical treatment of severe L5-S1 spondylolisthesis in children and adolescents. Results of intraoperative reduction, posterior interbody fusion, and segmental pedicle fixation","volume":"21","author":"Fabris DA","year":"1996","unstructured":"Fabris DA, Costantini S, Nena U. Surgical treatment of severe L5-S1 spondylolisthesis in children and adolescents. Results of intraoperative reduction, posterior interbody fusion, and segmental pedicle fixation. Spine (Phila Pa 1976). 1996;21(6):728\u2013733.10.1097\/00007632-199603150-00014"},{"issue":"7","key":"b3","series-title":"J Bone Joint Surg Am","doi-asserted-by":"publisher","first-page":"960","DOI":"10.2106\/00004623-198769070-00002","article-title":"Long-term follow-up of patients with grade-III and IV spondylolisthesis. Treatment with and without posterior fusion","volume":"69","author":"Harris IE","year":"1987","unstructured":"Harris IE, Weinstein SL. Long-term follow-up of patients with grade-III and IV spondylolisthesis. Treatment with and without posterior fusion. J Bone Joint Surg Am. 1987;69(7):960\u2013969.10.2106\/00004623-198769070-00002"},{"issue":"2","key":"b4","series-title":"Neurosurg Clin N Am","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.nec.2007.01.001","article-title":"Operative management of adult high-grade lumbosacral spondylolisthesis","volume":"18","author":"Acosta FL Jr","year":"2007","unstructured":"Acosta FL Jr, Ames CP, Chou D. Operative management of adult high-grade lumbosacral spondylolisthesis. Neurosurg Clin N Am. 2007;18(2):249\u2013254.10.1016\/j.nec.2007.01.001"},{"key":"b5","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"S49","DOI":"10.1097\/01.brs.0000155573.34179.7e","article-title":"Evaluation and management of high-grade spondylolisthesis in adults","volume":"30","author":"DeWald CJ","year":"2005","unstructured":"DeWald CJ, Vartabedian JE, Rodts MF, Hammerberg KW. Evaluation and management of high-grade spondylolisthesis in adults. Spine (Phila Pa 1976). 2005;30(6 suppl):S49\u2013S59.10.1097\/01.brs.0000155573.34179.7e"},{"issue":"3","key":"b6","series-title":"Neurosurg Clin N Am","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.nec.2019.02.002","article-title":"High-grade lumbar spondylolisthesis","volume":"30","author":"Beck AW","year":"2019","unstructured":"Beck AW, Simpson AK. High-grade lumbar spondylolisthesis. Neurosurg Clin N Am. 2019;30(3):291\u2013298.10.1016\/j.nec.2019.02.002"},{"issue":"5","key":"b7","series-title":"J Pediatr Orthop B","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1097\/01202412-200409000-00011","article-title":"Non-adjacent spondylolisthesis in Ehlers-Danlos syndrome","volume":"13","author":"Nematbakhsh A","year":"2004","unstructured":"Nematbakhsh A, Crawford AH. Non-adjacent spondylolisthesis in Ehlers-Danlos syndrome. J Pediatr Orthop B. 2004;13(5):336\u2013339.10.1097\/01202412-200409000-00011"},{"issue":"2","key":"b8","series-title":"J Spinal Disord Tech","doi-asserted-by":"publisher","first-page":"E41","DOI":"10.1097\/BSD.0b013e31829649fa","article-title":"A novel minimally invasive technique for the treatment of high-grade isthmic spondylolisthesis using a posterior transsacral rod","volume":"27","author":"Shedid D","year":"2014","unstructured":"Shedid D, Weil AG, Lieberman I. A novel minimally invasive technique for the treatment of high-grade isthmic spondylolisthesis using a posterior transsacral rod. J Spinal Disord Tech. 2014;27(2):E41\u2013E48.10.1097\/BSD.0b013e31829649fa"},{"key":"b9","article-title":"Medtronic Announces new screw for market-leading CD HORIZON solera spinal system","author":"Rocha V","unstructured":"Rocha V, Warren J. Medtronic Announces new screw for market-leading CD HORIZON solera spinal system. Medtronic. July 11, 2013. Accessed March 29, 2021. https:\/\/news.medtronic.com\/2013-07-11-Medtronic-Announces-New-Screw-for-Market-Leading-CD-HORIZON-R-SOLERA-R-Spinal-System"},{"issue":"2","key":"b10","series-title":"J Can Chiropr Assoc","first-page":"162","article-title":"High-grade spondylolytic spondylolisthesis","volume":"61","author":"Emary PC","year":"2017","unstructured":"Emary PC, Eberspaecher SA, Taylor JA. High-grade spondylolytic spondylolisthesis. J Can Chiropr Assoc. 2017;61(2):162\u2013166."},{"key":"b11","article-title":"Ehlers Danlos syndrome","author":"Miklovic T","unstructured":"Miklovic T, Sieg VC. Ehlers Danlos syndrome. StatPearls. 2021. Accessed March 29, 2021. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK549814\/"},{"key":"b12","series-title":"Surg Neurol Int","doi-asserted-by":"publisher","first-page":"416","DOI":"10.25259\/SNI_676_2020","article-title":"Pedicular lumbosacral spine fusion for adult\/adolescent lumbar developmental high-grade spondylolisthesis","volume":"11","author":"Elnokaly MA","year":"2020","unstructured":"Elnokaly MA, Adawi MM, Nabeel AM. Pedicular lumbosacral spine fusion for adult\/adolescent lumbar developmental high-grade spondylolisthesis. Surg Neurol Int. 2020;11:416.10.25259\/SNI_676_2020"},{"issue":"4","key":"b13","series-title":"J Spine Surg","doi-asserted-by":"publisher","first-page":"650","DOI":"10.21037\/jss-20-597","article-title":"Retrospective radiographic analysis of anterior lumbar fusion for high grade lumbar spondylolisthesis","volume":"6","author":"Kalani MA","year":"2020","unstructured":"Kalani MA, Kouloumberis P, Richards AE,  Retrospective radiographic analysis of anterior lumbar fusion for high grade lumbar spondylolisthesis. J Spine Surg. 2020;6(4):650\u2013658.10.21037\/jss-20-597"},{"issue":"2","key":"b14","series-title":"Orthop Traumatol Surg Res","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.otsr.2015.12.016","article-title":"Reduction and fusion in high-grade L5-S1 spondylolisthesis by a single posterior approach. Results in 50 patients","volume":"102","author":"Moreau S","year":"2016","unstructured":"Moreau S, Lonjon G, Guigui P,  Reduction and fusion in high-grade L5-S1 spondylolisthesis by a single posterior approach. Results in 50 patients. Orthop Traumatol Surg Res. 2016;102(2):233\u2013237.10.1016\/j.otsr.2015.12.016"},{"issue":"6","key":"b15","series-title":"Clin Orthop Relat Res","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1007\/s11999-013-3241-y","article-title":"Minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis and degenerative spondylosis: 5-year results","volume":"472","author":"Park Y","year":"2014","unstructured":"Park Y, Ha JW, Lee YT, Sung NY. Minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis and degenerative spondylosis: 5-year results. Clin Orthop Relat Res. 2014;472(6):1813\u20131823.10.1007\/s11999-013-3241-y"},{"issue":"6","key":"b16","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1227\/NEU.0000000000000913","article-title":"Surgical outcomes for minimally invasive vs open transforaminal lumbar interbody fusion: an updated systematic review and meta-analysis","volume":"77","author":"Khan NR","year":"2015","unstructured":"Khan NR, Clark AJ, Lee SL,  Surgical outcomes for minimally invasive vs open transforaminal lumbar interbody fusion: an updated systematic review and meta-analysis. Neurosurgery. 2015;77(6):847\u2013874.10.1227\/NEU.0000000000000913"},{"issue":"1","key":"b17","series-title":"J Orthop Surg Res","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1186\/s13018-019-1266-y","article-title":"Open versus minimally invasive TLIF: literature review and meta-analysis","volume":"14","author":"Hammad A","year":"2019","unstructured":"Hammad A, Wirries A, Ardeshiri A,  Open versus minimally invasive TLIF: literature review and meta-analysis. J Orthop Surg Res. 2019;14(1):229.10.1186\/s13018-019-1266-y"}],"container-title":["Journal of Neurosurgery: Case Lessons"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/2\/2\/article-CASE21196.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/2\/2\/article-CASE21196.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/2\/2\/article-CASE21196.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T14:52:58Z","timestamp":1770303178000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/2\/2\/article-CASE21196.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,12]]},"references-count":34,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3171\/case21196","relation":{},"ISSN":["2694-1902"],"issn-type":[{"value":"2694-1902","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,12]]}}}