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Magnetic resonance imaging (MRI) and computed tomography of the skull showed an endonasal infection, which had already destroyed the frontal skull base and caused a large frontal intracranial abscess. The second patient was a 29-year-old woman with multiple pre-existing conditions, who was initially admitted to the hospital due to a COVID-19 infection and later developed a hemiparesis of the right side. Here, the MRI scan showed an abscess configuration in the left motor cortex. In both cases, rapid therapy was performed by surgical clearance and abscess evacuation followed by antifungal, antidiabetic, and further supportive treatment for several weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>Both cases are indicative of a possible correlation of mucormycosis in the setting of severe immunosuppression involved with COVID-19, both iatrogenic with the use of steroids and previous medical history. Furthermore, young and supposedly healthy patients can also be affected by this rare disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case21567","type":"journal-article","created":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T06:04:21Z","timestamp":1656914661000},"source":"Crossref","is-referenced-by-count":0,"title":["Intracerebral mucormycosis after COVID-19: illustrative cases"],"prefix":"10.3171","volume":"3","author":[{"given":"Amin I.","family":"Nohman","sequence":"first","affiliation":[{"name":"Clinic of Neurosurgery, University Hospital Heidelberg, Baden-W\u00fcrttemberg, Germany; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meltem","family":"Ivren","sequence":"additional","affiliation":[{"name":"Clinic of Neurosurgery, University Hospital Heidelberg, Baden-W\u00fcrttemberg, Germany; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Klein","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Medical Microbiology and Hygiene, University Hospital Heidelberg, Baden-W\u00fcrttemberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elham","family":"Khatamzas","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Medical Microbiology and Hygiene, University Hospital Heidelberg, Baden-W\u00fcrttemberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Unterberg","sequence":"additional","affiliation":[{"name":"Clinic of Neurosurgery, University Hospital Heidelberg, Baden-W\u00fcrttemberg, Germany; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Giese","sequence":"additional","affiliation":[{"name":"Clinic of Neurosurgery, University Hospital Heidelberg, Baden-W\u00fcrttemberg, Germany; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","article-title":"Coronavirus (COVID-19) Dashboard","unstructured":"World Health Organization. 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